Clinical trials: Autism Spectrum Disorders
Autism Spectrum Disorder
Building Resilience and Appropriate Independence in Young Adults With Autism
This study evaluates the effects of a 12-week life-skills resilience curriculum for young adults with autism. The project utilizes a cohort single arm design.
- Trial name
- NCT03842332
- Testing
- Life Skills and Resilience Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Reducing Challenging Behaviors in Children With Autism Through Digital Health
School-based behavioral approaches to managing challenging behaviors in children with ASD are limited by three key factors: 1) children with ASD often have difficulties communicating their emotions; 2) it is challenging to…
- Trial name
- NCT05277194
- Testing
- KeepCalm app
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder
Community-based Adaptive Autism Intervention for Toddlers
The proposed study (CAIT: Community-based Adaptive Autism Intervention for Toddlers) aims to determine the most optimal sequence of interventions for improving the social- communicative, language and cognitive outcomes of…
- Trial name
- CAIT (NCT04283045)
- Testing
- JASPER, JASPER Plus+
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Effects of Lactobacillus Plantarum PS128 in Children With ASD
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that can cause significant social, communication and behavioral deficits. Probiotics are regarded as active microorganisms.
- Trial name
- NCT05307744
- Testing
- PS128
- Where
- Taiwan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
Preliminary Efficacy of Occupational Therapy Integrating Horses on Self-regulation in Youth With Autism
The goal of this clinical trial is to learn about occupational therapy integrating horses for autistic youth. The main questions it aims to answer are: Does occupational therapy integrating horses improve self-regulation in…
- Trial name
- NCT05846932
- Testing
- OTEE HORS, OT Clinic
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Autism Spectrum Disorder, Anxiety
Specifying and Treating Anxiety in Autism Research
In the Specifying and Treating the Anxiety Phenotype in Autism Spectrum Disorder (STAAR) study, we conducted a16-week randomized comparative treatment trial of the Behavioral Intervention for Anxiety in Children with Autism…
- Trial name
- STAAR (NCT03279471)
- Testing
- Sertraline, CBT/BIACA
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Davis
Autism Spectrum Disorder, EEG With Periodic Abnormalities
Safety and Efficacy of tPBM for Epileptiform Activity in Autism
For this study, the proposed intervention will be noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM) - to the brains of autistic children with abnormal EEGs with epileptiform discharges or…
- Conditions
- Autism Spectrum Disorder, EEG With Periodic Abnormalities, Epilepsy, Neurodevelopmental Disorders
- Trial name
- tPBM (NCT06352372)
- Testing
- noninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Richard Frye
Autism Spectrum Disorder, Gastrointestinal Symptoms
Combination Probiotic: BB-12 With LGG (Different Doses) in Treating Children With Autism Spectrum Disorder
This protocol is a blinded randomized controlled study of the effects of BB-12 with LGG at different doses in 70 healthy children with autism spectrum disorders at lower and higher doses over an 56-day period and a 28- day…
- Trial name
- NCT03514784
- Testing
- BB-12 with LGG (Higher Dose), BB-12 with LGG (Lower Dose)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Autism Spectrum Disorder, Mental Disorders
Physiological Mechanisms of Therapeutic Horseback Riding Intervention Effects in a Psychiatric Population of ASD Youth
This randomized control trial (RCT) seeks to assess the mechanisms underlying Therapeutic Horseback Riding's (THR) previously observed significant positive effects on ASD youth, particularly those with co-occurring psychiatric…
- Trial name
- NCT04606966
- Testing
- Therapeutic Horseback Riding, Barn Activity, Hybrid
- Where
- 2 sites in United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism, Autism Spectrum Disorder
First CRUSH: Piloting the Preliminary Feasibility and Acceptability of the Competence in Romance and Understanding Sexual Health (CRUSH) Curriculum
The goal of this clinical trial is to learn about the feasibility and acceptability of a behavioral intervention in designed to provide sexual education and improve the behavioral skills of autistic adults for intimate…
- Trial name
- NCT05910658
- Testing
- Competence in Romance and Understanding Sexual Health (CRUSH)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder
Expediting Access to Services for Equity
The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for Black toddlers under the age of 4 after…
- Trial name
- EASE (NCT06291246)
- Testing
- Virtual Family Navigation, Educational Materials
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder, Implementation Science
Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement With Mental Health Services for Youth With Autism
This project, Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement with Mental Health Services for Youth with Autism (ATTAIN NAV) is focused on adapting and implementing family…
- Conditions
- Autism Spectrum Disorder, Implementation Science, Mental Health, Behavioral Health
- Trial name
- ATTAIN NAV (NCT05344378)
- Testing
- ATTAIN NAV Technology-Enhanced Family Navigation Model
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 6, who have been diagnosed with moderate to severe autism.
- Trial name
- TPBMASD (NCT04660552)
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- JelikaLite LLC
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children - Open Label Study (TPBMASDOL)
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 7, who have been diagnosed with moderate to severe autism.
- Trial name
- NCT06359080
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- JelikaLite LLC
Autism Spectrum Disorder
Effect of a Wide Spectrum Nutritional Supplement on Mitochondrial Function in Children With Autism Spectrum Disorder
The objective of this study is to evaluate the metabolic effects of a comprehensive wide-spectrum supplement for children with ASD to determine whether it physiologically targets mitochondrial pathways known to be abnormal in…
- Trial name
- NCT03835117
- Testing
- Wide-spectrum nutritional supplement
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Rossignol Medical Center
Autism, Autism Spectrum Disorder
hCT-MSC in Children With Autism Spectrum Disorder
The purpose of this Phase II study is to determine the efficacy of human umbilical cord tissue-derived mesenchymal stromal cells (hCT-MSC) for improving social communication abilities in children with autism spectrum disorder…
- Trial name
- IMPACT (NCT04089579)
- Testing
- Cord Tissue Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Joanne Kurtzberg, MD
Autism Spectrum Disorder
Improving Dental Care and Oral Health in Children With Autism Spectrum Disorder
A randomized controlled trial (at sites) comparing the efficacy of the established AIR-P Dental Toolkit (control condition) to a combined regimen involving the Dental Toolkit and parent-mediated behavioral intervention…
- Trial name
- NCT03003221
- Testing
- AIR-P Dental Toolkit, Parent Training
- Where
- 2 sites in United States
- Volunteers
- 119 people
- Sponsor
- University of California, Irvine
Autism Spectrum Disorder
Care Improving Cognition for ADolescents on the Autism Spectrum
This is a validation study to evaluate the acceptability, feasibility and impact of CICADAS (Care Improving Cognition for ADolescents on the Autism Spectrum), a clinician-assisted, digital application that aims to prime the brain…
- Trial name
- CICADAS (NCT04562688)
- Testing
- CICADAS only, PEERS + CICADAS and then no-contact, PEERS + Active Comparator and then no-contact
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Posit Science Corporation
Autism Spectrum Disorder
HEARTS R34 Feasibility Study, Autistic Participants
The goal of this randomized clinical trial is to test whether the 6 sessions HEARTS Healthy Relationships classes increases the satisfaction that autistic adults feel about their friendships and dating relationships compared to a…
- Trial name
- HEARTS-R34 (NCT05608083)
- Testing
- HEARTS classes, Online discussion group
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Boston University Charles River Campus
Autism, Autism Spectrum Disorder
Intranasal Vasopressin Treatment in Children With Autism
The purpose of this clinical trial is to investigate the effectiveness of vasopressin nasal spray for treating symptoms associated with autism.
- Conditions
- Autism, Autism Spectrum Disorder, ASD
- Trial name
- NCT03204786
- Testing
- Vasopressin (USP) Injectable Solution [Vasostrict]
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Stanford University