Clinical trials: Auditory Perceptual Disorders
Analgesia
The Analgesic Effect of Auditory Inputs and Its Relation to Psychological and Neurobiological Mechanisms
The study investigates the analgesic effect of different auditory inputs. Employing a within-subject design, the study includes healthy participants that are exposed to thermal stimuli while listening to three different auditory…
- Trial name
- NCT03410563
- Testing
- Auditory inputs
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Central Auditory Disease, Auditory Processing Disorder, Central
taVNS Effect on Central Auditory Processing
The behavioral effects of vagus nerve stimulation (VNS) and observed activation in the auditory cortex with transcutaneous auricular VNS (taVNS) raise questions about their potential impact on auditory processing.
- Conditions
- Central Auditory Disease, Auditory Processing Disorder, Central, Auditory Processing Disorders, Vagus Nerve Stimulation
- Trial name
- NCT06970444
- Testing
- transcutaneous auricular vagus nerve stimulation (taVNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medipol University
Apraxia of Speech, Aphasia
Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech
Impaired speech production is a major obstacle to full participation in life roles by stroke survivors with aphasia and apraxia of speech.
- Conditions
- Apraxia of Speech, Aphasia, Cerebrovascular Accident
- Trial name
- NCT02094014
- Testing
- Normal Auditory Feedback, Masked Auditory Feedback, Altered Auditory Feedback
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Schizophrenia, Hallucinations
Transcranial Magnetic Stimulation for "Voices"
This study will determine the efficacy of MRI-guided transcranial magnetic stimulation (TMS)in reducing "voices" and other symptoms experienced by people with schizophrenia and schizoaffective disorder.
- Trial name
- NCT00308997
- Testing
- 1-hertz Repetitive Transcranial Magnetic Stimulation, Active 1-Hertz Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Yale University
Schizophrenia, Auditory Verbal Hallucinations
Neuronavigated rTMS for Treatment-Resistant Auditory Hallucinations
Auditory verbal hallucinations (AVH), such as hearing voices in the absence of an external sound source, are a common and distressing symptom of schizophrenia.
- Trial name
- fuNEEG (NCT07856368)
- Testing
- Neuronavigated repetitive transcranial magnetic stimulation (rTMS)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Psychiatric University Hospital, Zurich
Hallucinations, Auditory, Psychosis
Toward a Computationally-Informed, Personalized Treatment for Hallucinations
Auditory hallucinations are among the most distressing aspects of psychotic illness, and between 10 and 30% of people with hallucinations do not respond to antipsychotic medications.
- Trial name
- NCT04366518
- Testing
- Rivastigmine Transdermal System, Scopolamine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Yale University
Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature
Building a Computational Model of Auditory Hallucinations
Some people hear voices or sounds that other people cannot hear; these are called auditory hallucinations. The study aims to understand what is happening in the brain when this occurs and will use brain scans to learn more.
- Conditions
- Schizophrenia / Schizoaffective Disorder, Schizophrenia and Disorders With Psychotic Feature, Psychosis, SCHIZOPHRENIA 1 (Disorder)
- Trial name
- CLARITY WP1 (NCT07820553)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- King's College London
Schizophrenia
Bilateral Repetitive Transcranial Magnetic Stimulation for Auditory Hallucinations Original Study
This trial is designed to determine if administering repetitive transcranial magnetic stimulation (rTMS) simultaneously to two sites in the temporal lobes, one on the left and one on the right, produces greater improvements in…
- Trial name
- NCT00567281
- Testing
- Magstim Rapid 2 system triggering Magstim Super Rapid system, Magstim Rapid-2 system triggering Magstim Super Rapid system
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Unilateral Vocal Cord Paralysis, Central Auditory Processing Disorder
Early UVFP Management Based on Neurological Evidences (ION-UVFP) - Preliminary Study
The purpose of this preliminary study is to help clarify our hypotheses for the longitudinal study by investigating the relationship between vocal cord paralysis and central auditory processes and thus the interpretation of…
- Trial name
- NCT03966183
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Auditory Hallucinations
The Physalis Child : Identification of Cognitive and Emotional Factors
The aim of this study is to show presence of cognitive and emotional factors on the beginning and persistence of auditory hallucinations in non-psychotic children.
- Trial name
- NCT02567500
- Testing
- Patients with auditory hallucination, Patients without auditory hallucination
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fondation Lenval
Presbycusis
Computer-Based Auditory Rehabilitation
Hearing in noisy environments is a perceptual problem that is ubiquitous in modern industrialized societies. This particular listening context offers a particular challenge to individuals living with hearing impairment (30…
- Trial name
- NCT02147847
- Testing
- Video game based training 1, Video game based training 2
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Schizophrenia, Schizoaffective Disorder
Quantifying Abnormalities in Cortical Activation Associated With Auditory Hallucinations Using Functional Magnetic Resonance Imaging
The goal of the project is to characterize abnormalities in brain structure and function related to schizophrenia. The investigators will use advanced magnetic resonance imaging (MRI) techniques to measure the degree and…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Hallucinations
- Trial name
- NCT00288340
- Testing
- functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Refractory Schizophrenia
Repetitive Transcranial Magnetic Stimulation for Refractory Auditory Hallucinations in Schizophrenia
Studies using repetitive transcranial magnetic stimulation (rTMS) as a treatment for refractory auditory hallucinations (AH) in schizophrenia have shown promise.
- Trial name
- NCT01386918
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- Centre for Addiction and Mental Health
Verbal Auditory Hallucination, Psychotic Disorders
RELATE - Efficacy and Feasibility of a Cognitive Behavioural Module for Distressing Auditory Verbal Hallucinations
Auditory hallucinations (AH) are associated with distress and reduced functioning. Psychological interventions show some promising effects on psychopathology but have been less successful in reducing AH related distress, which…
- Conditions
- Verbal Auditory Hallucination, Psychotic Disorders, Psychosis, Schizophrenia
- Trial name
- RELATE (NCT04578314)
- Testing
- Relating Therapy, Treatment as usual
- Where
- 5 sites in Germany
- Volunteers
- 85 people
- Sponsor
- University of Hamburg-Eppendorf
Auditory Hallucination, Verbal, Treatment-resistant Schizophrenia
Comparaison of Avatar Therapy to Cognitive Behavioral Therapy in Schizophrenia With Treatment Refractory Hallucinations
Schizophrenia is associated with long-lasting health, social and financial burden for patients, families, caregivers and society.
- Trial name
- Phase3 (NCT04054778)
- Testing
- Avatar Therapy, Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Auditory Hallucinations, Schizophrenia
Neuro-VR: Augmenting a Virtual Reality-based Therapy With Biofeedback for Auditory Hallucinations
The primary goal of this pilot study is to examine the feasibility and acceptability of augmenting a Virtual Reality-based intervention for treating auditory hallucinations in schizophrenia with electroencephalogram (EEG)-based…
- Trial name
- Neuro-VR (NCT06628323)
- Testing
- Virtual Reality-based Intervention employing Neurofeedback, Virtual Reality-based Intervention
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Schizophrenia, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Schizophrenia Patients With Auditory Hallucinations
To investigate the treatment effect of continuous transcranial magnetic stimulation on schizophrenia patients with auditory hallucinations, and the underlying neural mechanism by functional MRI
- Conditions
- Schizophrenia, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging
- Trial name
- NCT02863094
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Schizophrenia
tDCS & Auditory Hallucinations in Schizophrenia
The aim of this study is to evaluate tDCS effects on schizophrenia symptoms, particularly on auditory verbal hallucinations. tDCS applied with cathodal (inhibitory) electrode over the left temporal parietal junction and anodal…
- Trial name
- NCT02227563
- Testing
- Active tDCS, control
- Where
- Israel
- Volunteers
- 3 people
- Sponsor
- Herzog Hospital
Auditory Hallucinations
CHALLENGE. A Randomised Clinical Trial Examining Virtual Reality Therapy
The study is a randomised, assessor-blinded parallel-groups superiority clinical trial, allocating a total of 266 patients to either the experimental intervention or standard intervention.
- Trial name
- NCT04661163
- Testing
- Psychotherapy
- Where
- Denmark
- Volunteers
- 270 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Schizophrenia, Auditory Hallucinations
A Pilot Double-blind Sham-controlled Trial of Repetitive Transcranial Magnetic Stimulation for Patients With Refractory Schizophrenia Treated With Clozapine
The primary outcome of this study is to evaluate the effects of low frequency subthreshold repetitive Transcranial Magnetic Stimulation applied to the left temporoparietal cortex of patients with refractory schizophrenia on the…
- Trial name
- NCT01015001
- Testing
- (1Hz) rTMS applied over the left temporoparietal cortex
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre