Clinical trials: Attention, open to volunteers
Attention-Deficit/Hyperactivity Disorder (ADHD)
Treating Young Children With Attention Deficit Hyperactivity Disorder
This project will evaluate the effectiveness of Methylphenidate versus Guanfacine in treating Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 3 through 5 years (inclusive), as measured by clinician rating of…
- Trial name
- TYCA (NCT07300956)
- Testing
- Guanfacine (GUA), Methylphenidate (MPH)
- Where
- 5 sites in United States
- Volunteers
- 370 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Mesenteric Ischemia
Blood Flow and Oxygenation in the Portal Vein in Subjects With Chronic Narrowing of the Blood Vessels to the Gut
In this study the investigators will, with an Magnetic Resonance Imaging (MRI) method, measure the oxygen content in the portal vein, which conduct the blood from the guts to the liver.
- Trial name
- NCT07182669
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
ADHD
Virtual Reality Attention Management
Problems with distraction are widespread in the 21st century, but for people with developmental delays or behavioral challenges they can have more damaging effects.
- Trial name
- VRAM (NCT03221244)
- Testing
- VR Treatment, VR Active Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Basic Science: Visual Attention in Healthy Participants, Basic Science: Neural Representations of Location
Probing the Role of Feature Dimension Maps in Visual Cognition: Impact of Task Demands and Spatial Attention (Expt 2.2)
How does one know what to look at in a scene? Imagine a "Where's Waldo" game - it's challenging to find Waldo because there are many 'salient' locations in the picture, each vying for one's attention.
- Trial name
- NCT07572630
- Testing
- Stimulus properties: task-defining feature
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Fibromyalgia Syndrome, Disease Burden
Fibromyalgia Disease Burden in Mothers of Children With Attention-Deficit/Hyperactivity Disorder
In this study, the investigators aimed to evaluate the impact of having a child diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) on parental disease burden in mothers diagnosed with Fibromyalgia Syndrome (FMS).
- Conditions
- Fibromyalgia Syndrome, Disease Burden, Attention-Deficit/Hyperactivity Disorder
- Trial name
- NCT07327775
- Testing
- Disease Burden
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sultan 1. Murat State Hospital
Hydrocephaly, CSF Shunts
Cefazolin Antibiotic Prophylaxis in Ventricular Shunt Surgery: Determination of Cerebrospinal Fluid Concentration During Valve Implantation
The objective is to determine the concentration of cefazolin in the cerebrospinal fluid after a recommended antiobiotic prophylaxis by 2g of cefazolin.
- Conditions
- Hydrocephaly, CSF Shunts, Antibiotic Prophylaxis
- Trial name
- CC -PIV (NCT07067736)
- Testing
- Cefazolin antibiotic prophylaxis
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Central Nervous System (CNS) Metastases, Breast Cancer
A Phase II Observational Clinical Study on the Relationship Between Cerebrospinal Fluid Drug Concentration and Efficacy of Trastuzumab Deruxtecan in Central Nervous System Metastatic Breast Cancer
Approximately 5-15% breast cancer patients develop brain metastases. Current local treatments (surgery/radiotherapy) are associated with significant complications, and systemic treatments have limited efficacy.
- Trial name
- BCBM006 (NCT07653893)
- Testing
- No Interventions
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fudan University
ADHD
Central Executive Training and Parent Training for ADHD
The goal of the current project is to combine two evidence- based treatments for school-aged children with ADHD: Central Executive Training (CET) and Behavioral Parent Training (BPT).
- Trial name
- NCT05492422
- Testing
- Central Executive Training (CET), Behavioral Parent Training (BPT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Florida State University
Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD)
Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT (Full Scale RCT)
Interventions for parents of children with NDD face two pivotal challenges. Firstly, many overlook the consequential influence of parenting stress, symptoms of parental anxiety and depression on the well-being of parent-child…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD), Attention Deficit Disorder With Hyperactivity (ADHD)
- Trial name
- NCT06779422
- Testing
- Pai.ACT, Positive parenting advice
- Where
- Hong Kong
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Myopia, Myopia Progression
The Effectiveness and Safety of Two Low-concentration Atropine Sulfate Eye Drops (0.01%/0.02%) for Delaying the Pediatric Myopia Progression
The clinical trial aims to test the effectiveness and safety of two low-dose atropine sulfate eye drops for delaying myopia progression in children and adolescents.
- Trial name
- NCT06708156
- Testing
- Atropine sulfate eye drops 0.01%, Atropine sulfate eye drops 0.02%
- Where
- 25 sites in China
- Volunteers
- 606 people
- Sponsor
- Oupushifang Pharmaceutical Technology Co., Ltd.
Zinc Concentration in DBS
Nourishing for Knowledge: Fish Powder in School Meals in Malawi
Background: This randomized controlled trial (RCT) is a research component of a Food and Agriculture Organization of the United Nations (FAO) project in Malawi.
- Trial name
- FAO/LUANAR (NCT07085871)
- Testing
- Fish Powder
- Where
- 3 sites in Malawi
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Food and Agriculture Organization of the United Nations (FAO)
Perceived Stress, Positive and Negative Affect
Efficacy of Interactive Audio-based Mindfulness ChatGPT-Powered Intervention on Well-being
Brief mindfulness intervention is a short form is a form of short-duration practice, typically delivered for around 30 minutes or less (Howarth et al., 2019).
- Conditions
- Perceived Stress, Positive and Negative Affect, State Anxiety, Self Control
- Trial name
- NCT07333365
- Testing
- Interactive Mindfulness Breathing ChatGPT-Powered Intervention, Interactive Mind Wandering ChatGPT-Powered Intervention, Mindfulness Breathing Audio-only
- Where
- Singapore
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Singapore Management University
Attention Deficit Hyperactivity Disorder
R61/33 - VR Study Phase 4
The goal of this larger parallel group randomized trial is to test the impact of a virtual reality program for improving the ability of emerging adults (age 18-25) with attention deficit hyperactivity disorder (ADHD) to stay…
- Trial name
- NCT07169760
- Testing
- Meta Quest 3 VR Headset with noise cancelling headphones
- Where
- 2 sites in United States
- Volunteers
- 252 people
- Sponsor
- Rutgers, The State University of New Jersey
ADHD
Identification of Early Biomarkers of Pre-school ADHD
ADHD affects around 5% of children and manifests itself as hyperactivity, attention difficulties and motor control and balance problems.
- Trial name
- Bio-PreTDAH (NCT07440992)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ADHD - Attention Deficit Disorder With Hyperactivity
Retail-Grade Weighted Blanket Effectiveness on ADHD-related Sleep Disturbances (BEAD)
The goal of this clinical trial is to investigate if a commercially available (retail-grade) weighted blanket can improve sleep in children with Attention Deficit Hyperactivity Disorder (ADHD) and sleep disturbances.
- Trial name
- Sweet BEAD (NCT07588659)
- Testing
- Sleep Intervention with weighted device
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
ADHD - Attention Deficit Disorder With Hyperactivity
Study of the Nutritional, Inflammatory, and Metabolic Endophenotypes of Attention-Deficit/Hyperactivity Disorder (ADHD)
This study aims to better understand the biological mechanisms involved in attention deficit hyperactivity disorder (ADHD) and to clarify why some children and adolescents respond well to methylphenidate (MPH)-the most commonly…
- Trial name
- ANIME (NCT07417878)
- Testing
- Clinical and Biological Evaluation - ADHD Cases, Clinical and Biological Evaluation - Controls
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
ADHD
Impact of Stimulants and In-Scanner Motion on Attentive Task Performance in ADHD (ADHD_NFB)
The goal of this interventional study is to learn the effects that stimulant medication prescribed to ADHD individuals has in their performance of attentive tasks, as measured by images and data collected through neuroimaging…
- Trial name
- ADHD_NFB (NCT06779825)
- Testing
- fMRI Neurofeedback attention task
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Children's Hospital
Thyroid Associated Ophthalmopathies, Eye Tracking
Eye Tracking Study on Eye Movement Function and Visual Attention Patterns in Patients With Thyroid-Associated Ophthalmopathy
This study focuses on eye health and visual function in patients with Thyroid-Associated Ophthalmopathy (TAO), a condition that often causes bulging eyes and restricted eye movement.
- Trial name
- TAO-A (NCT07381413)
- Testing
- Non-invasive Eye Tracking Assessment
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity
Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
The goal of this action research project is to develop and implement nature- and activity-based group interventions across health care, school and leisure settings in Southern Norway.
- Conditions
- Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity, Autism, Tourette Syndrome
- Trial name
- NCT07203469
- Testing
- Universal approach, Selective approach, Outdoor therapy
- Where
- 2 sites in Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Brain Tumor, Pediatric
Irradiation in Paediatrics: Neurocognition, Neuroimaging and Evaluation of Memory and Attention
This is a prospective, open-label, multicentric study designed to correlate the dose delivered to the hippocampus with declarative memory deficits 2 years after radiotherapy treatment in a paediatric population who had received…
- Trial name
- IPANEMA (NCT06599879)
- Testing
- Neuropsychological assessments:
- Where
- 14 sites in France
- Volunteers
- 130 people
- Sponsor
- Institut Claudius Regaud