Clinical trials: Attachments
Pelvic Organ Prolapse
Long-term Evaluation of the Efficacy and Safety of Splentis for the Treatment of Primary Apical Pelvic Organ Prolapse
This prospective, multi center cohort trial aims to evaluate the efficacy and safety of hysteropexy using Splentis via the vaginal route in primary uterine prolapse
- Trial name
- SAXO (NCT05042453)
- Testing
- Splentis® POP Tissue Anchoring System
- Where
- 7 sites in Germany
- Volunteers
- 140 people
- Sponsor
- Promedon
Degeneration of Lumbar Intervertebral Disc
Comparison of the Aspen Device Versus Pedicle Screws for Supplemental Posterior Fixation in Lumbar Interbody Fusion
The purpose of this clinical investigation is to evaluate the Aspen™ device compared to pedicle screw instrumentation for posterior fixation in the treatment of patients with degenerative disc disease and/or spondylolisthesis.
- Trial name
- NCT01549366
- Testing
- Aspen Spinous Process Fixation Device, Pedicle Screws
- Where
- 3 sites in United States
- Volunteers
- 64 people
- Sponsor
- Zimmer Biomet
Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis
Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy
The purpose of this study is to evaluate the safety and preliminary efficacy of NeoFuse in subjects with a diagnosis of degenerative disc disease (DDD) at 2 or more adjacent cervical vertebral levels between C3-C4 to C7-T1.
- Conditions
- Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT01097486
- Testing
- NeoFuse, Allograft
- Where
- 8 sites in United States
- Volunteers
- 24 people
- Sponsor
- Mesoblast, Ltd.
Migraine Disorders
Efficacy, Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS Versus Placebo in the Treatment of a Single Attack of Acute Migraine Headache
Efficacy, Safety, Tolerability and Pharmacokinetics of BIBN 4096 BS in patients with a single acute migraine attack with or without aura
- Trial name
- NCT02198339
- Testing
- BIBN 4096 BS
- Volunteers
- 126 people
- Sponsor
- Boehringer Ingelheim
Ventral Hernia
Tacks Versus Glue for Mesh Fixation in Laparoscopic Ventral Hernia Repair Treating Defects Between 2 and 5 cm Width
In laparoscopic ventral hernia repair, an abundance of methods has been developed to fix the mesh to the abdominal wall, including sutures (non-absorbable or absorbable), staples (non-absorbable or absorbable), clips, tacks…
- Trial name
- NCT03429374
- Testing
- Liquiband Fix8, Absorbable tack
- Where
- 11 sites in Belgium
- Volunteers
- 16 people
- Sponsor
- Duomed
Degenerative Disc Disease, Degenerative Spondylolisthesis
Evaluation Of Spinelink® Fixation In The Treatment Of Degenerative Spondylolisthesis And Spinal Instability
The purpose of this open, multi-center study is to prospectively collect outcome data on patients who are having lumbar spinal fusion surgery with implantation of the SpineLink® system.
- Trial name
- NCT00726310
- Testing
- SpineLink® , SpineLink® II
- Where
- 2 sites in United States
- Volunteers
- 202 people
- Sponsor
- Zimmer Biomet
Dental Implants, Dental Prosthesis Failure
Attachment Systems for Implant Overdenture
The aim of this randomized controlled trial is to compare peri-implant tissue health, number of complications, and patient's preference between two unsplinted overdenture attachments.
- Trial name
- NCT03640910
- Testing
- OT Equators® (Rhein83), Locator® (Zest)
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Rhein 83 Srl
Heart Failure, Congestive
Evaluation of the Safety and Effectiveness of the OPTIMIZER System in Subjects With Heart Failure: FIX-HF-5
The purpose of this study is to determine whether treatment with the OPTIMIZER System is safe and effective in patients with moderate to severe heart failure symptoms.
- Trial name
- NCT00112125
- Testing
- OPTIMIZER System
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- Impulse Dynamics
Degenerative Disc Disease
Titanium Surgical Mesh and MOSS-Miami Screws for Lumbar Fusion.
The purpose of this study is to determine the clinical success of DePuy Spine Titanium Surgical Mesh with MOSS Miami Spinal Fixation System Pedicle Screws in the treatment of one or two levels of degenerative disc disease of the…
- Trial name
- NCT00215319
- Testing
- Lumbar I/F with cage and pedicle screws
- Where
- 2 sites in United States
- Volunteers
- 139 people
- Sponsor
- DePuy Spine
Cataract
A Comparison of the Diagnostic Confidence and Image Quality Between the Eyoto Theia (RDSL) and a Predicate Device.
A clinical study has been identified as a requirement for the RDSL (Theia). This study involves a clinical comparison of the imaging from the RDSL with that of a predicate device.
- Trial name
- NCT05783583
- Testing
- Remote Digital Slit Lamp
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Eyoto Group Ltd
Wounds and Injuries
Clinical Investigation of Two Different Wound Dressings
The primary objective of this investigation is to evaluate changes on Peri-Wound skin from baseline to termination when using two different wound dressings The secondary objectives are to evaluate pain before, during, and after…
- Trial name
- NCT02904200
- Testing
- Silicon adhesive dressing, Acrylic adhesive dressing
- Where
- 2 sites in Sweden
- Volunteers
- 2 people
- Sponsor
- Molnlycke Health Care AB
Spinal Disease
A Feasibility Study to Evaluate the TURRIS Facet Fusion System in Lumbar Spinal Surgery
This is a prospective, exploratory study to verify intra-operative handling and safety and to collect preliminary short-term safety and efficacy data of the Turris® Facet Fuser, a small bioresorbable device for the immediate…
- Trial name
- NCT02294669
- Testing
- Turris Facet Fuser
- Where
- 2 sites in Switzerland
- Volunteers
- 3 people
- Sponsor
- SpineWelding AG
Lumbar Disc Disease
Study of the Long-Term Outcomes of Posterior Spinal Fixation With the Karma Device
The primary objective of this clinical study is to measure fusion rate in patients at 12 months following lumbar fusion in combination with posterior fixation using the Karma® device.
- Trial name
- NCT04984213
- Testing
- Karma Posterior Fixation Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spinal Elements
Femur Fractures
The CHINA TFNA Study
This is a prospective, multicenter, randomized, controlled, two-arm, non-inferiority study which will be conducted in China to support registration of a cephalomedullary nailing system (TFNA) that currently is available globally.
- Trial name
- TFNA (NCT03635320)
- Testing
- TFNA, PFNA-II
- Where
- 9 sites in China
- Volunteers
- 188 people
- Sponsor
- Synthes GmbH
Irritable Bowel Syndrome (IBS)
qQ-lab Daily-IBS for Irritable Bowel Syndrome
Primary purpose: To assess satisfaction with overall improvement in symptoms, including individual bowel symptoms, after 4 weeks of administration of gQ-lab to patients with irritable bowel syndrome (IBS).
- Trial name
- NCT03964103
- Testing
- gQ-lab daily
- Volunteers
- 100 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Dental Implant Placement
Supracrestal Tissue Attachment Dimensions & Peri-implant Health
Decision making in regards to the 3D implant positioning in partially edentulous sites is a complex process particularly when there are adjacent teeth present.
- Trial name
- NCT05552768
- Testing
- Bone level-driven placement, Biological width-driven placement guidelines
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MIS Implant Technologies, Ltd