Clinical trials: Atrophic Gastritis
Chronic Atrophic Gastritis (CAG)
Association of Sleep Quality With Pathologic Staging, Acupuncture Treatment in Patients With Chronic Atrophic Gastritis: a Cross-sectional Study
In order to inform clinical treatment decisions and maximize treatment outcomes, this observational study set out to examine the relationship between pathological severity and sleep quality in patients with CAG.
- Trial name
- NCT06912178
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yi Liang
Cancer Screening Tests
Blood Tests for Gastritis and Gastric Neoplasms
Helicobacter pylori infection rate is decreasing in younger population; however, biennial gastroscopy is still recommended for all Koreans aged between 40 and 75 years.
- Trial name
- NCT05883345
- Testing
- Serum blood test for Helicobacter pylori immunoglobulin G, pepsinogen, and gastrin-17 levels
- Where
- South Korea
- Volunteers
- 1,490 people
- Sponsor
- Konkuk University Medical Center
Gastric Cancer, Gastric (Stomach) Cancer
Gastric Cancer Endoscopic Screening in an Intermediate-risk Country - ROGCAS, a Dual-centre Pilot Program
Endoscopic screening of gastric cancer combined with screening colonoscopy
- Conditions
- Gastric Cancer, Gastric (Stomach) Cancer, Atrophic Gastritis, Intestinal Metaplasia of Gastric Mucosa
- Trial name
- ROGCAS (NCT06316882)
- Testing
- Screening endoscopy
- Where
- Portugal
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Unidade Local De Saúde Do Norte Alentejano
Atrophic Gastritis
Atrophic Gastritis Predicts the Risk of Gastric Cancer
Despite declining incidence rates, gastric cancer (GC) ranks the fourth leading cause of cancer-related mortality and the fifth most common cancer worldwide, with the highest incidence reported in Eastern Asia.
- Trial name
- NCT06203327
- Testing
- Esophagogastroscopy (OLGA 0-Ⅰ), Esophagogastroscopy (OLGA II), Esophagogastroscopy (OLGA III-IV)
- Where
- China
- Volunteers
- 2,042 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Atrophic Gastritis
Observation on the Efficacy of Radiofrequency Ablation for Patients With Moderate to Severe Gastric Atrophy With Enterosis With or Without Atrophy of Intraepithelial Neoplasia: An Observational Study
The aim of this observational study was to understand the effect of radiofrequency ablation on subjects with moderate to severe gastric atrophy with enterocolitis with or without low-grade intraepithelial neoplasia who underwent…
- Trial name
- NCT06751212
- Testing
- Radiofrequency ablation alone
- Volunteers
- 62 people
- Sponsor
- Xiuli Zuo
Chronic Atrophic Gastritis (CAG)
Correlation Among Various OLGA and OLGIM Stages, Digestive Symptom Scores, and Acupuncture Treatment in Patients with Chronic Atrophic Gastritis
Brief Summary Template for the Study: The goal of this observational study is to examine the relationship between digestive symptom scores, serum pepsinogen indices, and histopathological OLGA and OLGIM systematic staging of the…
- Trial name
- NCT06707701
- Testing
- acupuncture
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yi Liang
Chronic Atrophic Gastritis
Objective Study on Tongue Diagnosis of Chronic Atrophic Gastritis
Chronic atrophic gastritis with intestinal metaplasia or dysplasia is called precancerous lesions of gastric cancer ( PLGC ). It is an important stage in the transformation of normal mucosa to gastric cancer and is significantly…
- Trial name
- NCT06489132
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Gastric Cancer, Gastric Intestinal Metaplasia
Cytosponge for Gastric Intestinal Metaplasia
Gastric cancer has a very poor prognosis. The disease is often diagnosed at a late stage, when curative treatment options are limited or ineffective.
- Conditions
- Gastric Cancer, Gastric Intestinal Metaplasia, Gastric Atrophy
- Trial name
- CyGIM (NCT05657080)
- Testing
- Cytosponge-TFF3
- Where
- United Kingdom
- Volunteers
- 226 people
- Sponsor
- University of Cambridge
Chronic Atrophic Gastritis
Clinical Study of Umbilical Cord Blood Mononuclear Cell Therapy for the Treatment of Chronic Atrophic Gastritis
To evaluate the efficacy and safety of umbilical cord blood mononuclear cells in the treatment of chronic atrophic gastritis.
- Trial name
- NCT05808010
- Testing
- Mononuclear cells, Weifuchun+Hydrotalcite/L-Glutamine and Sodium Gualenate Granules
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong Provincial Hospital
Atrophic Gastritis, Artificial Intelligence
AI-assisted White Light Endoscopy to Identify the Kimura-Takemoto Classification of Atrophic Gastritis
Grading endoscopic atrophy according to the Kimura-Takemoto classification can assess the risk of gastric neoplasia development.
- Conditions
- Atrophic Gastritis, Artificial Intelligence, Endoscopy
- Trial name
- NCT05916014
- Testing
- Diagnostic Test: The diagnosis of Artificial Intelligence and endosopists
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shandong University
Atrophic Gastritis With Low-grade Intraepithelial Neoplasia
Fuzheng Nizeng Formula for Chronic Atrophic Gastritis With Low-grade Intraepithelial Neoplasia, a Multicenter Randomized Controlled Trial
Fuzheng Nizeng Formula (FZNZ) is derived from the classic formula Liujunzi Decoction. Former pilot study found that FZNZ promoted the recovery of gastric atrophy and relieve the relative symptoms.
- Trial name
- NCT06324825
- Testing
- Fuzhegn Nizeng Decoction, Moluodan granules
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University First Hospital
Chronic Atrophic Gastritis
Multi-omics Analyses on Etiology and Early Detection of Stomach Cancer Precursor Lesions
The overall aim is to utilize multi-omics approach to identify novel etiopathogenesis and early detection biomarkers for stomach cancer precursor lesions.
- Trial name
- NCT06267703
- Testing
- Metabolomic profiling
- Where
- Sweden
- Volunteers
- 12,599 people
- Sponsor
- Karolinska Institutet
CAG - Chronic Atrophic Gastritis, EGC - Early Gastric Cancer
LCI in Chronic Atrophic Gastritis and Early Gastric Cancer
Color change is a useful marker for the endoscopic identification of chronic atrophic gastritis (CAG) and gastric cancer (GC). Several histopathological studies have suggested a correlation between certain gastrointestinal…
- Trial name
- NCT06152263
- Testing
- Compare color information and mucosal microvascular density
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Stomach Neoplasm, Chronic Atrophic Gastritis
The Gastric HormonE BioMarkers of Preneoplastic Lesions Study
The goal of the study is to understand whether blood levels of hormones produced or metabolized in the stomach reflect the health of the stomach lining.
- Conditions
- Stomach Neoplasm, Chronic Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- GEM (NCT06085677)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Autoimmune Diseases, Helicobacter Pylori Gastritis
Pyloric or Pseudopyloric Metaplasia of the Corpus Mucosa in Autoimmune Gastritis
The study is aimed to investigate the different rates of pyloric/ pseudopyloric metaplasia or spasmolytic polypeptide-expressing metaplasia (SPEM) of corpus between autoimmune gastritis and H. pylori-infected non-ulcer dyspepsia.
- Conditions
- Autoimmune Diseases, Helicobacter Pylori Gastritis, Anemia, Pernicious, Metaplasia
- Trial name
- PM_in_AIG (NCT05238181)
- Testing
- Assess pyloric or pseudopyloric metaplasia of corpus by H&E stains, Assess pyloric or pseudopyloric metaplasia of corpus by TFF2 immunohistochemistry stains, The assessment of corpus-predominant gastritis index (CGI), Operative Link for Gastritis Assessment (OLGA), and Operative Link on Gastric Intestinal Metaplasia assessment (OLGIM)
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Cheng-Kung University Hospital
Gastric Cancer
Pilot Study of Stomach Cancer Early Detection and Prevention With Endoscopy
Screening esophagogastroduodenoscopy (EGD )provides three distinct opportunities to decrease gastric cancer (GC) morbidity and mortality.
- Trial name
- NCT05566899
- Testing
- esophagogastroduodenoscopy (EGD)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Gastric Cancer, Atrophic Gastritis
AG & IM in CA Stomach Protocol
This is a multi-center prospective case control study aiming to compare different methods of risk stratification models in predicting the risk of gastric cancer development.
- Conditions
- Gastric Cancer, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT04184960
- Testing
- Gastroscopy and gastric biopsies
- Where
- 4 sites in Hong Kong, Japan and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chronic Atrophic Gastritis
Treatment of Atrophic Gastritis After HP Eradication With Modified Liujunzi Decoction Based on Syndrome Differentiation
This is an observational cohort study of clinical efficacy study.The purpose of this topic is to evaluate the efficacy and safety of Modified Liujunzi Decoction based on syndrome differentiation in patients with chronic atrophic…
- Trial name
- NCT05388890
- Testing
- MLD, WFC
- Where
- China
- Volunteers
- 286 people
- Sponsor
- Peking University First Hospital
Gastric Cancer, Dysplasia Stomach
Endoscopic Surveillance on a High-risk Population for Gastric Cancer in Latin America: The ECHOS Cohort Study.
The goal of this observational study is to evaluate the risk factors associated with incident HGD/GA in patients with CAG with or without IM who are enrolled in endoscopic surveillance, as well as to compare GA incidence…
- Conditions
- Gastric Cancer, Dysplasia Stomach, Atrophic Gastritis, Helicobacter Pylori Infection
- Trial name
- ECHOS (NCT05969444)
- Where
- 2 sites in Chile
- Volunteers
- 685 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Helicobacter Pylori Infection, Atrophic Gastritis
Effect of H. Pylori Eradication on the Reversibility of Atrophic Gastritis and Intestinal Metaplasia in Korean Patients
Helicobacter pylori (H. pylori) infection has been associated with a development of atrophic gastritis and intestinal metaplasia. H.
- Conditions
- Helicobacter Pylori Infection, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT02691637
- Where
- South Korea
- Volunteers
- 1,450 people
- Sponsor
- Seoul National University Bundang Hospital