Clinical trials: Atrial Fibrillation
Persistent Atrial Fibrillation
Optimized Ablation of the Posterior Wall in Persistent Atrial Fibrillation
The design of this study is an intervention, randomized, controlled study and contains three randomized groups：（1）PVI group；（2）PVI+PWI group;（3）PVI+PWI+EGM group.
- Trial name
- NCT07122336
- Testing
- PVI, PWI, EGM
- Where
- China
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Mitral Valve Insufficiency, Atrial Fibrillation
Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation
A large left atrial (LA) volume, which represents chronic diastolic dysfunction, is associated with a poor outcome, regardless of systolic function.
- Conditions
- Mitral Valve Insufficiency, Atrial Fibrillation, Heart Failure
- Trial name
- NCT01172184
- Testing
- Cardiac catheterization
- Where
- Taiwan
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Cardiovascular Diseases, Cardiac Arrhythmia
Solutions for Atrial Fibrillation Edvocacy (SAFE)
The aim of this demonstration project is to create an additional access point in the community at local pharmacies for atrial fibrillation screening, detection, and referral to physicians for follow-up and initiation of…
- Conditions
- Cardiovascular Diseases, Cardiac Arrhythmia, Atrial Fibrillation
- Trial name
- SAFE (NCT05067114)
- Testing
- Screening, detection and referral for atrial fibrillation
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- American Pharmacists Association Foundation
Atrial Fibrillation, Atrial Flutter
HeartBeam ECG Registry
The HeartBeam ECG Registry will collect ECG recordings acquired with the HeartBeam System with relevant clinical information in clinical settings.
- Conditions
- Atrial Fibrillation, Atrial Flutter, Bradycardia, Tachycardia
- Trial name
- NCT07501299
- Testing
- Electrocardiogram (ECG)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- HeartBeam, Inc.
Atrial Fibrillation
Improving the Quality of Care for Atrial Fibrillation by Promoting Patient-Centered Decision Making
The primary aim of this proposal is to determine the effectiveness of a decision support tool on improving the process of shared decision-making for treatment on nonvalvular atrial fibrillation (NVAF) compared to receipt of usual…
- Trial name
- AFIB (NCT00829478)
- Testing
- Decision Aid for Atrial Fibrillation, Usual Care
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- VA Connecticut Healthcare System
AF, Ablation of Atrial Fibrillation
Comparison of Different Electroporation Systems in the Ablation Treatment of Atrial Fibrillation
The participant is invited to participate in a clinical study comparing three different techniques for treating atrial fibrillation (AF) called electroporation systems.
- Trial name
- PFA Champion (NCT06646887)
- Testing
- Electroporation
- Where
- 2 sites in Croatia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Atrial Fibrillation, Atrial Flutter
Decreasing Hospital Admissions From the ED for AAFF
Acute atrial fibrillation and flutter (AAFF) is characterized by rapid heart rates with onset less than seven days. It's the most common type of palpitation treated in the Emergency Department (ED).
- Trial name
- RAFF-3 (NCT03627143)
- Testing
- KTI activities
- Where
- 12 sites in Canada
- Volunteers
- 846 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Typical Atrial Flutter, Risk Factors With Future Development of Atrial Flutter
Pulmonary Vein Isolation To Reduce Future Risk Of Atrial Fibrillation In Patients Undergoing Typical Flutter
The purpose is to compare long term occurrence of atrial arrhythmias including atrial fibrillation (AF) and thromboembolic complications including cerebrovascular events (CVE) in patients with typical atrial flutter (AFLT)…
- Trial name
- REDUCE AF (NCT01710150)
- Testing
- CTI ablation alone, CTI ablation and Pulmonary vein isolation (PVI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Atrial Fibrillation
Fish Oil for Reduction of Atrial Fibrillation After Cardiac Surgery
The primary objective of this study is to determine if omega-3 polyunsaturated fatty acids reduce atrial fibrillation and other outcomes after cardiac surgery.
- Trial name
- FISH (NCT00446966)
- Testing
- Omega Three Polyunsaturated fatty acids
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Chirag Sandesara
Systemic Inflammatory Response Syndrome
INFLACOR - Clinical and Genetic Predictors of Inflammation Related Complications After Heart Surgery
The aim of the study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of inflammatory response related complications in patients undergoing heart surgery with use of cardiopulmonary…
- Trial name
- INFLACOR (NCT01020409)
- Testing
- cardiac surgery with CPB use
- Where
- Poland
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Atrial Fibrillation, Atrial Flutter
Get With the Guidelines Atrial Fibrillation Registry
Get With The Guidelines-Atrial Fibrillation is designed to assist hospital care teams in consistently providing the latest evidence-based treatment for their AFib patients.
- Trial name
- GWTG-AF (NCT06245187)
- Testing
- GWTG Atrial Fibrillation program
- Where
- United States
- Volunteers
- 17,198 people, healthy volunteers welcome
- Sponsor
- American Heart Association
Atrial Fibrillation
Fed-Fasted, Single and Multiple Ascending Dose Trial of XEN-D0103
This study is an evaluation of the safety and tolerability of XEN-D0103 in healthy subjects. Part 1 assesses the safety, tolerability and blood levels of the ascending single doses of XEN-D0103.
- Trial name
- NCT02390258
- Testing
- 10mg XEN-D0103, 30mg XEN-D0103, 60mg XEN-D0103
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Xention Ltd
Persistent Atrial Fibrillation
PerAF: AF Termination vs Prespecified Ablation
The design of this study is an intervention, randomized, controlled study and contains two randomized groups：（1）AF-termination group；（2）Prespecified-ablation group.
- Trial name
- NCT06837441
- Testing
- Atrial Fibrillation Termination, Prespecified Ablation
- Where
- China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation, Obstructive Sleep Apnea
OSA Prevalence in Atrial Fibrillation Patients: Jordanian Study
Current Knowledge: Countless studies have been conducted to study the relationship between OSA and AF, and a significant association has been established between both diseases, owing to the numerous shared risk factors and a wide…
- Trial name
- NCT05990010
- Testing
- Berlin Questionnaire
- Where
- Jordan
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Murmur, Heart, Innocent Murmurs
Real-World Evaluation of Eko Algorithms in a Point of Care Setting
The purpose of this research is to prospectively test and validate the utility of Eko artificial intelligence (AI) plus Eko Murmur Analysis Software (EMAS) murmur characterization in algorithm in a real world, point-of-care…
- Conditions
- Murmur, Heart, Innocent Murmurs, Heart Murmurs, Pathologic Murmur
- Trial name
- NCT05459545
- Testing
- Use of Eko CORE and Eko CORE 500 electronic stethoscope
- Where
- 5 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Eko Devices, Inc.
Paroxysmal Atrial Fibrillation, Catheter Ablation Strategies
Unexcitability Along the Ablation as an Endpoint for Atrial Fibrillation Ablation
to assess the near-term (12 months) efficacy of pulmonary vein isolation.
- Trial name
- NCT01724437
- Testing
- catheter based pulmonary vein isolation
- Where
- Germany
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Atrial Fibrillation, Stroke
Anticoagulation With Rivaroxaban in Cardioversion -The ARC Study
The purpose of this study is to determine that a new drug called "Rivaroxaban®" is effective in preventing patients from forming clots after their heart rhythm has been reset by the cardiologist with an electrical device.
- Conditions
- Atrial Fibrillation, Stroke, Thrombo-embolism, Bleeding
- Trial name
- ARC (NCT01747746)
- Testing
- Rivaroxaban, Warfarin and Enoxaparin
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cook County Health
Drug Absorption
Influence of CPB and Mini CPB to the Absorption of the Metoprolol
Influence of perfusion, miniperfusion and off pump coronary artery bypass grafting to the absorbtion of metoprolol postoperatively, hypothesis in that miniperfusion and off pump surgery does not decrease absorbtion of the…
- Trial name
- Minimeto (NCT01728272)
- Testing
- blood concentration of metoprolol
- Where
- Finland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Atrial Fibrillation
Study to Assess the Safety, Tolerability, Pharmacokinetic of Thrv-1268
This is a single-center, randomized, double-blind, placebo-controlled study to be conducted in 2 parts: single ascending dose (SAD) incorporating a food effect arm and multiple ascending dose (MAD).
- Trial name
- NCT06507839
- Testing
- THRV-1268
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Thryv Therapeutics, Inc.
Atrial Fibrillation (AF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
An AI-ECG-Based Approach for Dynamic Assessment of Heart Failure Risk and Myocardial Recovery Following Atrial Fibrillation Ablation
Background Artificial intelligence-enabled electrocardiography (AI-ECG) has emerged as a promising digital biomarker for detecting latent myocardial dysfunction and predicting cardiovascular risk.
- Trial name
- NCT07708818
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital