Clinical trials: Atrial Arrhythmia
Atrial Fibrillation or Pulmonary Embolism, Need of Long Term Oral Anticoagulation Therapy (OAT)
Rivaroxaban Compared to Vitamin K Antagonist Upon Development of Cardiovascular Calcification
The following trial hypothesis will be proved: In patients with atrial fibrillation and/ or pulmonary embolism standard anticoagulant treatment with coumadin/phenprocoumon is associated with accelerated coronary or valvular…
- Conditions
- Atrial Fibrillation or Pulmonary Embolism, Need of Long Term Oral Anticoagulation Therapy (OAT), Existent Coronary or Valvular Calcification, or Both and Agatston Score > 50 in at Least One Location
- Trial name
- NCT02066662
- Testing
- Rivaroxaban or Marcumar
- Where
- 3 sites in Germany
- Volunteers
- 192 people
- Sponsor
- RWTH Aachen University
Coronary Artery Disease, Atrial Fibrillation
Reviving Early Diagnosis of Cardiovascular Disease in the Utrecht Health Project
The goal of this randomized trial is to compare the diagnostic yield of a screen-like early diagnosis strategy to usual primary care to detect coronary artery disease (CAD), atrial fibrillation (AF), heart failure (HF), and/or…
- Conditions
- Coronary Artery Disease, Atrial Fibrillation, Heart Failure, Valvular Heart Disease
- Trial name
- RED-LRGP (NCT05775354)
- Testing
- Early diagnosis strategy
- Where
- Netherlands
- Volunteers
- 1,476 people
- Sponsor
- UMC Utrecht
Atrial Fibrillation
A Ring-type Wearable Device for Atrial Fibrillation Among Ambulatory Patients
This study investigates diagnostic performance of a ring-type wearable device for detecting atrial fibrillation. This is a prospective cohort registry study began after the date of IRB approval and until 31th Dec. 2023.
- Trial name
- NCT04024124
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Atrial Fibrillation, Oral Anticoagulation
Management of Patients With Atrial Fibrillation Undergoing Coronary Artery Stenting
Treatment of patients suffering from atrial fibrillation pose problems when percutaneous coronary intervention with stent implantation (PCI-S) is performed.
- Conditions
- Atrial Fibrillation, Oral Anticoagulation, Percutaneous Coronary Intervention
- Trial name
- AFCAS (NCT00596570)
- Testing
- PCI
- Where
- Finland
- Volunteers
- 996 people
- Sponsor
- University of Turku
Paroxysmal Atrial Fibrillation
Boston Scientific's Single Shot LUMINIZE RF Balloon Catheter in the Treatment of Symptomatic, Drug Refractory Paroxysmal Atrial Fibrillation
To establish the safety and effectiveness of the LUMINIZE RF Balloon Catheter System for treatment of symptomatic, drug refractory, recurrent, paroxysmal atrial fibrillation (PAF).
- Trial name
- VISUALISE AF (NCT03852420)
- Testing
- LUMINIZE RF Balloon Catheter
- Sponsor
- Boston Scientific Corporation
Atrial Fibrillation
Gene Expression Profiling in Subjects With Postoperative Atrial Fibrillation After Cardiac Surgery (GENEXPRO Surg)
Atrial fibrillation is a type of irregular heartbeat that is common after having heart surgery. There may be many different reasons why some people get atrial fibrillation after their heart surgery.
- Trial name
- NCT00833313
- Testing
- Atrial biopsy
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Brigham and Women's Hospital
Atrial Fibrillation
aMAZE Study: LAA Ligation Adjunctive to PVI for Persistent or Longstanding Persistent Atrial Fibrillation
This study is a prospective, multicenter, randomized (2:1) controlled study to evaluate the safety and effectiveness of the LARIAT System to percutaneously isolate and ligate the Left Atrial Appendage from the left atrium as an…
- Trial name
- aMAZE (NCT02513797)
- Testing
- LARIAT + PVI, Pulmonary Vein Isolation
- Where
- 53 sites in United States
- Volunteers
- 600 people
- Sponsor
- AtriCure, Inc.
Atrial Fibrillation, Stroke
DU-176b Phase 2 Dose Finding Study in Subjects With Non-valvular Atrial Fibrillation
This study will be conducted in male and female subjects aged 18 to 80 years, inclusive, with non-valvular AF and a CHADS2 Score of at least 1. Subjects will be treated on an outpatient basis.
- Trial name
- NCT00806624
- Testing
- DU-176b tablets, Warfarin tablets
- Where
- 4 sites in China, Singapore and 2 more
- Volunteers
- 234 people
- Sponsor
- Daiichi Sankyo Co., Ltd.
Atrial Fibrillation, Persistent
VOLTage Mapping in Atrial Fibrillation
The purpose of this study is to retrospectively analyze electroanatomical data collected during persistent atrial fibrillation ablation procedures, combined with pre-ablation cardiac CT data, in order to: define a new method for…
- Trial name
- VOLT-AF (NCT04832646)
- Testing
- atrial fibrillation ablation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Central Hospital, Nancy, France
Atrial Fibrillation, Venous Thromboses
Fearon Algorithm in Warfarin Patient Self-Management
This study aims to explore the feasibility of a novel, patient-specific algorithm for adjusting warfarin doses during chronic anticoagulation therapy.
- Conditions
- Atrial Fibrillation, Venous Thromboses, Heart Valve Diseases
- Trial name
- NCT03911661
- Testing
- Fearon warfarin dosing algorithm, Usual care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Atrial Fibrillation
Apixaban in Patients Who Undergo CIED Procedure- Randomized Pilot Study
This study is being done to determine if apixaban is more safe, when compared to warfarin, at reducing the risk of bleeding during CIED procedures.
- Trial name
- Apixaban (NCT02450682)
- Testing
- Apixaban, Warfarin
- Where
- United States
- Sponsor
- Mayo Clinic
Stroke, Ischemic
DELTA (Detecting and Predicting Atrial Fibrillation in Post-Stroke Patients)
Atrial Fibrillation (AF) is an abnormal heart rhythm. Because AF is often asymptomatic, it often remains undiagnosed in the early stages. Anticoagulant therapy greatly reduces the risks of stroke in patients diagnosed with AF.
- Trial name
- NCT05795842
- Testing
- wearable wristband model, Samsung Galaxy Watch 6, Standard of care extended ECG monitoring
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Emory University
Atrial Fibrillation
HERA FIb Registry for Patients With Atrial Fibrillation
The single-center HERA AFIb registry was created to assess real-world prevalence, demographic characteristics and management of patients with atrial fibrillation (AF) in the era of novel oral anticoagulant regimes (NOAC)…
- Trial name
- NCT05995561
- Testing
- no intervention is planned.
- Where
- Germany
- Volunteers
- 12,297 people
- Sponsor
- University Hospital Heidelberg
Tachyarrhythmia, Atypical Atrial Flutter
Outcome of Induced Atypical Atrial Flutter
Background: Atypical atrial flutter (AAF) is an increasingly relevant clinical problem. Despite advancements in mapping and ablation techniques, the general management of these patients remain challenging especially when mapping…
- Conditions
- Tachyarrhythmia, Atypical Atrial Flutter, Induction of Arryhthmia, Clinical Outcome
- Trial name
- NCT06323499
- Testing
- Induction of atypical atrial flutter
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- University Hospital, Essen
Atrial Fibrillation
Clinical Performance of Withings Move ECG Software for Atrial Fibrillation Detection
Withings Move ECG watch is designed to record ECG and detect automatically atrial fibrillation. The aim of this study is to validate the performance of Move ECG watch to detect atrial fibrillation compared to a reference 12-lead…
- Trial name
- ECG-SW1 (NCT04493749)
- Testing
- ECG measurement
- Where
- 3 sites in France
- Volunteers
- 234 people
- Sponsor
- Withings
Atrial Fibrillation, Arrhythmia
Telemetric Arrhythmia Diagnosis in Adults
The purpose of this study is to assess efficacy of prolonged Full Disclosure electrocardiogram (ECG) monitoring and signal analysis using advanced telemetric technology in comparison with a standard Holter ECG recording and an…
- Trial name
- TELEMARC1 (NCT01265758)
- Testing
- Prolonged telemetric Full Disclosure ECG recording.
- Where
- 2 sites in Poland
- Volunteers
- 360 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Atrial Fibrillation
Atrial Fibrillation Monitoring on Patients With Lymphoma After Chemotherapy
This prospective cohort study is to investigate the incidence of atrial fibrillation after chemotherapy by aplying wearable ECG recoder and the risk factors on patients with newly diagonsed lymphoma
- Trial name
- NCT05454878
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese PLA General Hospital
Atrial Fibrillation, Heart Failure, Diastolic
The Effect of Different Low-Level Tragus Stimulation Parameters On Autonomic Nervous System Function
Low level transcutaneous vagus nerve stimulation (LLTS) involves delivery of electrical impulses transcutaneously at the auricular branch of vagus nerve and it has been shown to have anti-inflammatory and anti-arrhythmic effects.
- Trial name
- LLT-SPANS (NCT04682704)
- Testing
- Parasym
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Atrial Fibrillation, Cathter Ablation
A Randomized Controlled Study of Ablation Pursuing Atrial Fibrillation Termination as a Procedural Endpoint in Patients With Persistent Atrial Fibrillation
This is a prospective, randomized, multi-center trial that aims to investigate whether termination of atrial fibrillation can be used as an ablation endpoint for persistent atrial fibrillation (PersAF).
- Conditions
- Atrial Fibrillation, Cathter Ablation, Endpoint
- Trial name
- NCT05921734
- Testing
- AF-termination Group, Prespecified-ablation Group
- Where
- 2 sites in China
- Volunteers
- 480 people
- Sponsor
- Shanghai Chest Hospital
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Warfarin for the first time…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947998
- Testing
- Rivaroxaban (Xarelto, Bay59-7939), Warfarin, Antiplatelet drugs
- Where
- United Kingdom
- Volunteers
- 50,299 people
- Sponsor
- Bayer