Clinical trials: Asthma Exacerbations
Acute Otitis Media (AOM), Strep Pharyngitis
Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma
This study evaluates the diagnostic performance, usability, and clinical utility of the Medentum Diagnostik platform, a multisensor device with integrated software and artificial intelligence, in pediatric patients with asthma…
- Conditions
- Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
- Trial name
- NCT07500532
- Testing
- Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medentum Innovations
Asthma, Asthma Attack
Optimisation of ASthma In Those With Uncontrolled Symptoms (OASIS)
A digital tool, called ReferID has been developed to facilitate the review of asthma patients. It aims to assist in the identification of patients with uncontrolled and/or severe asthma and to ensure a timely referral to…
- Conditions
- Asthma, Asthma Attack, Asthma Persistent, Covid19
- Trial name
- OASIS (NCT04941001)
- Testing
- ReferID
- Where
- United Kingdom
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Rhinovirus Infection in Asthma
Mechanisms of Rhinovirus Induced Asthma Exacerbations
We, the investigators, hypothesise that there are distinct gene profiles in rhinovirus-induced acute exacerbations of asthma. We further hypothesise that these changes in gene expression involve both known mediators of the asthma…
- Trial name
- NCT01159782
- Testing
- Rhinovirus infection
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Rhinovirus Infection in Asthma
Mechanisms of Interplay Between Allergy and Viruses in Asthma
The aim of this study is to investigate the mechanisms of interplay between allergy (IgE and Th2 mediated inflammation) and virus infection in the development of asthma, as well as the risk and severity of acute exacerbations of…
- Trial name
- NCT01773590
- Testing
- Rhinovirus Infection
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma Acute
Characterization of Natural Killer Cells in Severe Asthma Patients in Comparison With Control Subjects
Asthma is a common chronic bronchial disease affecting 300 million people worldwide. The disease can be severe when it is not managed properly or when it is not controlled by treatments.
- Trial name
- NKAS (NCT06015256)
- Testing
- blood sample
- Where
- France
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Asthma
Evaluation of Negative Inspiratory Flow in Children With Acute Asthma
There are different inhalers used for the treatment of asthma and they work differently and require different technique for the optimal drug delivery to the lungs. One of the inhalers is the Dry Powder Inhaler (DPI).
- Trial name
- NCT05762978
- Testing
- In-Check Dial, Inhaler Device
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Asthma Exacerbation, Emergency Department
Efficacy of High-Dose Continuous Intravenous Magnesium Sulfate Infusion vs Standard Intravenous Magnesium Sulfate Therapy in Status Asthmaticus in the ED
The goal of this clinical is to compare treatment outcomes between high dose continuous IV Magnesium and standard therapy in the management of acute exacerbation of asthma in the emergency department.
- Conditions
- Asthma Exacerbation, Emergency Department, Magnesuim Sulfate, High Dose
- Trial name
- HIMAG-ED-STAT (NCT07795970)
- Testing
- ้High-dose Magnesium sulphate, standard-dose Magnesium Sulfate
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Asthma
HFS in the Assessement and Management of Severe Asthma Attack Among Fifth Year Medical School Students
Bedside clinical case learning, such for respiratory distress, represent a challenge for medical teachers, especially in critical conditions.
- Trial name
- SimAG (NCT02776358)
- Testing
- High Fidelity Simulation, Video case
- Where
- Tunisia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Asthma Exacerbations
A Cohort Study of Risk Factors and Prognosis for Frequent Acute Asthma Exacerbations Phenotype
Acute asthma exacerbations are an important public health problem and a major cause of disease progression and healthcare burden for people with asthma. Frequent acute exacerbations are likely to be a distinct asthma phenotype.
- Trial name
- NCT06621056
- Testing
- not applicable for observational research
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital