Clinical trials: Asthma, completed
Severe Asthma
Follow-up of Children With Severe Asthma at Adult Age
Most of clinical cohorts focused on the course of asthma over time and on the different phenotypes of asthma have investigated children and adults separately. The passage from childhood to adulthood is scarcely explored.
- Trial name
- S2AEA (NCT05032209)
- Testing
- follow-up of children with severe asthma in adulthood
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
Stimulation of the Cervical Sympathetic Ganglion for Treatment of Asthma
The purpose of this study is to evaluate if stimulating the nerve involved with airway constriction, while undergoing procedures that are known to cause asthma exacerbations, decreases the level of asthma attack experienced.
- Trial name
- NCT01724307
- Testing
- Neurostimulation of stellate ganglion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Jonathan Parsons
Asthma, Moderate Asthma
Study of Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of REGN3500 in Adults With Moderate Asthma
Purpose of this study is to assess the safety and tolerability of multiple ascending subcutaneous doses of REGN3500 to moderate asthmatics.
- Trial name
- NCT02999711
- Testing
- REGN3500
- Where
- 3 sites in United Kingdom
- Volunteers
- 23 people
- Sponsor
- Regeneron Pharmaceuticals
Food; Allergy, Anaphylactic Shock, Asthma in Children
Omalizumab in Severe Asthmatics With Food Allergy
A prospective assessment of the impact of Omalizumab in terms of efficacy, safety, and quality of life (FA-QoL) in patients with moderate/severe asthma and history of anaphylaxis to peanut, tree nuts, fish, egg, milk, and/or…
- Trial name
- OSAFA (NCT06316414)
- Testing
- Omalizumab
- Where
- Italy
- Volunteers
- 65 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Asthma
A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Uncontrolled Severe Asthma
This is a Phase IIb, randomized, placebo-controlled, double-blind, multicenter, multi-arm study which will evaluate efficacy, safety, and pharmacokinetic of MSTT1041A compared with placebo as add-on therapy in participants with…
- Trial name
- NCT02918019
- Testing
- MSTT1041A
- Where
- 138 sites in United States, Argentina and 13 more
- Volunteers
- 517 people
- Sponsor
- Hoffmann-La Roche
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Asthma, Bronchial
Use of Montelukast to Treat Children With Mild to Moderate Acute Asthma
The primary objective of this study is to evaluate if children with acute asthma given a single dose of oral prednisolone with a subsequent daily five-day course of oral Montelukast will achieve a therapeutic failure rate at day…
- Trial name
- NCT00213252
- Testing
- Montelukast plus prednisolone, Prednisolone
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- The Hospital for Sick Children
Bronchiolitis, Pneumonia
National Observatory of Children Hospitalized for Acute Respiratory Distress or Lower Respiratory Tract Infections
This study is an observational, multicenter and prospective study for surveillance of case of hospitalised children acute respiratory distress or lower respiratory tract infections
- Conditions
- Bronchiolitis, Pneumonia, Asthma
- Trial name
- OVNI (NCT06112132)
- Where
- France
- Volunteers
- 1,827 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne
Asthma, Sleep Apnea Syndromes
Service Development: Assessing Non-attendance Rates in Outpatient Clinics
Many studies have shown a high non-attendance rate in hospital outpatient clinics. The investigators have found a non-attendance rate of 25% in their asthma clinics and would like to investigate whether a reminder phone call will…
- Conditions
- Asthma, Sleep Apnea Syndromes, Tuberculosis, COPD
- Trial name
- NCT00129649
- Testing
- Telephone reminder call
- Where
- United Kingdom
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Chronic Rhinosinusitis, Aspirin Exacerbated Respiratory Disease
Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease
Aspirin-Exacerbated Respiratory Disease, or AERD, consists of aspirin sensitivity, asthma and nasal polyps. It is currently managed by chronic steroid use, multiple endoscopic sinus surgeries and/or aspirin desensitization.
- Conditions
- Chronic Rhinosinusitis, Aspirin Exacerbated Respiratory Disease, Asthma, Aspirin Sensitivity
- Trial name
- NCT01778465
- Testing
- Low salicylate diet, Normal Diet
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Asthma
Efficacy of Symbicort pMDI Administered Once Daily in Adolescents and Adults During 12 Weeks - STEM
The purpose of this study is to compare a dose of Symbicort taken once daily with other dosage regimens of Symbicort , budesonide and placebo for the treatment of asthma in adolescents and adults
- Trial name
- NCT00652392
- Testing
- budesonide/formoterol
- Volunteers
- 750 people
- Sponsor
- AstraZeneca
Asthma, Distal Lung Inflammation
Mentored Patient-Oriented Research Career Development Award
Asthmatics have inflammation in the large airways (tubes through which air travels in and out of the lungs). The large airways are located in the central lung.
- Trial name
- NCT00203684
- Testing
- Flunisolide-HFA, Flunisolide-CFC
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Asthma, Healthy Volunteers
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of RV1729
RV1729 is a new medicine being developed for possible treatment of asthma and smoking related lung disease (also known as chronic obstructive pulmonary disease - COPD).
- Trial name
- NCT01813084
- Testing
- RV1729 single dose, RV1729: 14 day repeat dose
- Where
- 2 sites in United Kingdom
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Respivert Ltd
Severe Eosinophilic Asthma
Study to Characterise Patients Receiving Benralizumab in the Framework of an Individualized Access Program in Spain
Observational, retrospective study in adults (≥18 years) with severe asthma (maintenance treatment with high dose inhaled corticosteroids combined with long-acting agonist β2) and eosinophilic phenotype, who at the discretion of…
- Trial name
- ORBE (NCT04126499)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- AstraZeneca
Asthma
Therapeutic Equivalence Study of HCP0910 250/50 Mcg to Seretide 250 Diskus in Asthmatic Patients
The purpose of this study is to prove that HCP0910 is therapeutically equivalent to Seretide 250 Diskus when repeatedly dosed to Asthmatic patients.
- Trial name
- NCT01521455
- Testing
- HCP0910, Seretide Diskus
- Where
- 7 sites in South Korea
- Volunteers
- 56 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Asthma
Asthma and Quantifying Delivery Of Radio Labeled Aerosol
Introduction: Inhalation therapy has been established as an efficient route to treat asthma exacerbations, but coupled to noninvasive ventilation (NIV) remains quite challenging.
- Trial name
- NCT01823926
- Testing
- Noninvasive ventilation, Jet nebulizer, The vibrating mesh nebulizer (VMN)
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- Universidade Federal de Pernambuco
COVID-19, Coronavirus Infections
Audio Data Collection for Identification and Classification of Coughing
An open access study that will define and collect digital measures of coughing in multiple populations and public spaces using various means of audio data collection.
- Conditions
- COVID-19, Coronavirus Infections, Hay Fever, Asthma
- Trial name
- NCT04326309
- Where
- United States
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- HealthMode Inc.
Asthma Brittle
Exploring Asthma Exacerbations in Mepolizumab Treated Patients
This is a multicentre, observational study focusing on exacerbation events in patients with severe eosinophilic asthma on Mepolizumab.
- Trial name
- NCT03324230
- Where
- 4 sites in United Kingdom
- Volunteers
- 146 people
- Sponsor
- Queen's University, Belfast
Childhood Asthma, Passive Smoke Exposure
The Invisible Trigger: A Quasi-Experimental Study on the Effect of Passive Smoke Exposure and Counselling Intervention in Childhood Asthma
This study evaluates the effect of passive smoke exposure on childhood asthma and the role of structured counseling in reducing SHS exposure and improving asthma control.
- Trial name
- Asthma (NCT07069192)
- Testing
- Counselling
- Where
- Pakistan
- Volunteers
- 126 people
- Sponsor
- Foundation University Islamabad
Asthma, Sleep
Sleep Quality in High School Students With Asthma
The overall goal of this project is to develop and to preliminarily validate a novel intervention to be delivered in the high school setting that integrates two evidence-based, school-based interventions for urban adolescents…
- Conditions
- Asthma, Sleep, Asthma in Children
- Trial name
- NCT03073187
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Columbia University
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