Clinical trials: Arthrosis, open to volunteers
Knee Osteoarthritis (OA), Total Knee Anthroplasty
Tourniquet Vs. No-Tourniquet Technique in Total Knee Arthroplasty at the University Hospital of the West Indies
The goal of this clinical trial is to determine whether performing total knee replacement surgery (total knee arthroplasty, TKA) without a tourniquet is clinically equivalent to performing the procedure with a tourniquet in…
- Trial name
- NCT07506434
- Testing
- pneumatic tourniquet
- Where
- Jamaica
- Volunteers
- 30 people
- Sponsor
- The University of The West Indies
Knee Osteoarthritis, Physical Activity Behaviour
Person-Centred Digital Rehabilitation for Knee Osteoarthritis
This study aims to improve our understanding of how people with knee osteoarthritis think about, regulate, and adapt their physical activity while participating in Joint Academy's digital osteoarthritis programme for knee…
- Trial name
- NCT07875647
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Mälardalen University
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association
ACL Injury, Knee Osteoarthritis
The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.
The anterior cruciate ligament (ACL) is the main stabilizer of the knee joint, as it controls anteroposterior and rotatory knee laxity.
- Conditions
- ACL Injury, Knee Osteoarthritis, Knee Injuries
- Trial name
- NCT06442319
- Testing
- Platelet-rich plasma
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina
Osteoarthritis, Knee
Is Non Surgical CaRE Using Treat to Target Multimodal meDIcal Strategies aBLE to Delay or Avoid Total Knee Replacement?
Knee is the most common site of osteoarthritis. Treatment of knee osteoarthritis starts with a full course of medical therapy, followed by surgery to replace the knee with a prosthesis if this strategy fails, or in advanced…
- Trial name
- INCREDIBLE (NCT06643845)
- Testing
- arthroplasty, Medical and non-medical treatments
- Where
- 21 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Brest
Knee Osteoarthritis
Allogenic Mesenchymal Stem Cell Intraarticular Injection for Knee Osteoarthritis Therapy
This phase I and II double blinded randomized clinical controlled trial investigates the safety and efficacy of intraarticular knee injection with allogenic adipose derived mesenchymal stem cells (AD-MSC), in patients suffering…
- Trial name
- STEMJOINT (NCT05933434)
- Testing
- Allogenic adipose derived mesenchymal stem cells (AD-MSC), Saline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aarhus University Hospital
Hip Osteoarthritis
Bone Marrow Aspirate Concentrate Versus Triamcinolone Injection For Hip Osteoarthritis
This is a single site, randomized single blinded, two arm study researching the effects of bone marrow aspirate concentrate (BMAC) versus Triamcinolone in patients with hip osteoarthritis.
- Trial name
- NCT04990128
- Testing
- Aspire Needle + Emcyte PureBMC, Triamcinolone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Rheumatoid Arthritis
Cardiovascular Risk Factors in Rheumatoid Arthritis Patients ( Comparison Between Seronegative and Seropositive Cases )
The goal of this observational study is to learn about the long-term effects rheumatoid arthritis (RA) on cardiovascular system.
- Trial name
- NCT06738264
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Osteoarthritis
Evaluation of the Safety of LipiodolⓇ Embolization in Symptomatic Digital Osteoarthritis Refractory to Conventional Treatment
The goal of this clinical trial is to evaluate the safety of arterial embolization using Lipiodol® in patients with symptomatic hand osteoarthritis refractory to conventional treatment.
- Trial name
- EMBARDI (NCT06611007)
- Testing
- embolization therapy
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Degenerative Joint Disease of Knee, Rheumatoid Arthritis
Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.
Degenerative knee joint diseases are characterized by chronic pain, inflammation, and functional impairment. In these conditions, mast cell density in the synovial membrane is increased, resulting in an excessive release of…
- Trial name
- NCT07680101
- Testing
- Adelmidrol 2% / Hyaluronic Acid 1%, micronized Palmitoylethanolamide (mPEA) 300mg + ultramicronized Palmitoylethanolamide (umPEA) 600mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita di Verona
Adhesive Capsulitis of the Shoulder
Effectiveness of Instrumental Rehabilitation in Patients With Adhesive Capsulitis
The aim of this study is to evaluate the effectiveness of robotic training compared to conventional rehabilitation in patients with AC.
- Trial name
- NCT06766448
- Testing
- robotic training, conventionnal rehabilitation
- Where
- Morocco
- Volunteers
- 70 people
- Sponsor
- Mohammed V Souissi University
Hip OA
Non-weight Bearing in Hip Joint With Accompanying Joint Pain Might Not Progress Radiographic OA
As we have previously reported, the primary cause of hip OA with accompanying joint pain might be bone alterations which can be microfracture.
- Trial name
- NCT02329093
- Testing
- To MRI-detecting bone signal changes in radiographic hip OA
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Osteoarthritis
Vitamin D With Omega-3 or Metformin in Osteoarthritis
To determine the efficacy of vitamin D with omega-3 or metformin for reducing knee symptoms and effusion synovitis in patients with symptomatic knee osteoarthritis.
- Trial name
- NCT06328426
- Testing
- Vitamin D, Omega-3, Metformin
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Arthritis, Rheumatoid (RA)
AI-Based Medical Data Analysis for Differentiating Inflammatory vs Degenerative Joint Diseases in Elderly Patients
This study aims to evaluate the diagnostic accuracy of AI-assisted imaging analysis in differentiating between inflammatory and degenerative joint diseases in elderly patients.
- Trial name
- NCT07153315
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University
Juvenile Idiopathic Arthritis (JIA), Childhood Rheumatic Diseases
Investigation of Catastrophizing of Pain Reported by Parents in JIA Patients
Juvenile idiopathic arthritis (JIA) is the primary rheumatic disease reported to affect the pediatric population. Research suggests that parents' thoughts and feelings about their child's pain, specifically with JIA diagnosis…
- Trial name
- NCT07185750
- Testing
- Questionnaire application for JIA cases and their parents
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Axial Spondyloarthritis
Assessing the Feasibility of the Patient-Reported Outcomes Based Model for Community Care of Patients With Axial Spondyloarthritis Via a Type 1 Pilot Hybrid Effectiveness-Implementation Trial Using the RE-AIM Framework
The goal of this clinical trial is to facilitate the implementation of PROMs-based care for patients with axial spondyloarthritis.
- Trial name
- PROMise-Pilot (NCT06968247)
- Testing
- PROMise Model of Care
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- Singapore General Hospital
Psoriatic Arthritis
Rewiring the Brain-Immune Axis for Chronic Pain Using Transcranial Magnetic Stimulation in Psoriatic Arthritis
Despite advances in immunomodulatory therapies, many Psoriatic arthritis (PsA) patients experience persistent pain unrelated to clinical active joint inflammation.
- Trial name
- REACT (NCT07403890)
- Testing
- Active Repetitive Transcranial Magnetic Stimulation (rTMS), Control Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- NHS Greater Glasgow and Clyde
Participants With Obesity and Knee Osteoarthritis
A Trial of Ribupatide Injection in Participants With Obesity and Knee Osteoarthritis
The study is being conducted to evaluate the efficacy and safety of Ribupatide Injection in participants with obesity and knee osteoarthritis, and to explore its improvement on knee joint structure.
- Trial name
- NCT07709910
- Testing
- Ribupatide Injection
- Where
- China
- Volunteers
- 382 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
PARKINSON DISEASE (Disorder), Rigidity
Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD
Axial rigidity and loss of spinal mobility commonly observed in Parkinson's disease (PD) lead to postural deformities and substantial reductions in trunk flexibility.
- Conditions
- PARKINSON DISEASE (Disorder), Rigidity, Temporomandibular Disorders (TMDs), Mobility
- Trial name
- NCT07850674
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
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