Clinical trials: Arthroplasty
Deep Vein Thrombosis
Multimodal DVT Protocol in Tourniquet-less Total Knee Arthroplasty
The Cothera VPulse(tm) mechanical compression device (MCD) combines rapid intermittent sequential compression with cold therapy and is designed for single patient use in the home. Additionally, it can track patient compliance.
- Trial name
- NCT02102828
- Testing
- extended compression, Aspirin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- TriHealth Inc.
Knee Osteoarthritis
Evaluation of the Effect of SURGICEL® Powder in TKA
The study subjects are patients in our hospital's orthopedics department undergoing unilateral primary total knee arthroplasty (TKA) due to primary osteoarthritis.
- Trial name
- NCT06608992
- Testing
- SURGICEL® Powder
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Peking University Third Hospital
Knee Arthropathy, Knee Osteoarthritis
NLR and PLR Levels Following IPACK Block in Knee Arthroplasty
Effect of iPACK block on NLR and PLR following knee arthroplasty
- Conditions
- Knee Arthropathy, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT06304298
- Testing
- 0.9% Sodium Chloride Injection, Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Anesthesia Morbidity, Osteoarthritis, Knee
Evaluation of Anesthetic Techniques in Outpatient Total Joint Replacement Surgery in an Integrated Health Care Delivery System
The study is a retrospective cohort study of adult patients undergoing outpatient primary unilateral total knee or total hip replacement surgeries from 2017 to 2019 assessing for difference in anesthetic techniques and outcomes.
- Conditions
- Anesthesia Morbidity, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04203732
- Testing
- Anesthesia Type
- Where
- United States
- Volunteers
- 12,466 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hip Arthroplasty Replacement, Hip Arthroplasty, Total
Health-GIS Platform for Hip Replacement Rehabilitation Coordination
This study tests whether a mobile phone app with mapping technology can help patients find rehabilitation services faster after hip replacement surgery.
- Conditions
- Hip Arthroplasty Replacement, Hip Arthroplasty, Total, Rehabilitation, Hip Osteoarthritis
- Trial name
- NCT07201116
- Testing
- Health-GIS Rehabilitation Coordination Platform, Standard Rehabilitation Referral
- Where
- Kazakhstan
- Volunteers
- 142 people
- Sponsor
- Tulip Medicine
Arthropathy of Knee, Arthropathy of Hip
Results of the Application of the Clinical Pathway of Intensified Recovery Surgery for Adults in the Processes of Total Knee and Hip Replacement at the Maz Hospital
The investigators are going to study all the patients who have undergone surgery at the MAZ hospital from 2019 to the present for knee replacement and hip replacement.
- Trial name
- NCT05338255
- Where
- Spain
- Volunteers
- 534 people
- Sponsor
- Universidad de Zaragoza
Osteoarthritis, Knee
Study of the KinexConnect Telerehabilitation System (KCTRS)
A randomized, single-blind study comparing telerehabilitation at home with continuous passive motion (CPM) and a tablet-based patient engagement application (KinexConnect) versus traditional outpatient physical therapy (PT)…
- Trial name
- KCTRS (NCT04191798)
- Testing
- Telerehabilitation using the KinexConnect system for rehabilitation after TKA., Traditional outpatient PT for rehabilitation after TKA.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kinex Medical Company, LLC
Hip Osteoarthritis
Usability and Effectiveness of ReHub in Patients After Total Hip Arthroplasty
This is a randomized, non-blinded, parallel assignment, clinical trial for the evaluation of usability and effectiveness of ReHub, a telerehabilitation system made up of a cloud platform and an exercise kit with smart sensors…
- Trial name
- REHIP (NCT04176315)
- Testing
- Conventional Home-based Rehabilitation Plan, ReHub Home-based Rehabilitation Plan
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Bio-Sensing Solutions S.L. (DyCare)
Arthropathy of Hip, Hip Arthropathy
Pericapsular Nerve Group (PENG) Block Combined With Lateral Femoral Cutaneous Nerve (LFCN) Block or Wound Infiltration for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to compare two multimodal regional anesthesia strategies for postoperative analgesia in elective total hip arthroplasty (THA) performed via anterior approach.
- Conditions
- Arthropathy of Hip, Hip Arthropathy, Locoregional Anesthesia, Complication of Anesthesia
- Trial name
- Peng_lfcn/WI (NCT07284615)
- Testing
- PENG plus LFCN block, PENG plus WI
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Ospedale Edoardo Bassini
Total Knee Arthroplasty
Return Physical Activities After Total Knee Arthroplasty
The ability to resume physical activities, aerobic fitness and a healthy lifestyle without symptoms after total knee arthroplasty (TKA) remains unclear because studies show high rates of patient dissatisfaction.
- Trial name
- NCT04746144
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cincinnati Sportsmedicine Research and Education Foundation
Osteoarthritis
Fixation of OsseoTi™ Porous Structure Versus PPS (Porous Plasma Spray) Coating on the G7™ Acetabular Component for Primary Total Hip Arthroplasty
The primary objective of this project is to investigate, using RSA, acetabular implant migration of the OsseoTi™ G7 acetabular cup in comparison to conventional PPS coated G7 acetabular cup, and compare liner wear of thinnest…
- Trial name
- NCT02316704
- Testing
- THA with G7 PPS coted acetabular component, THA with G7 OsseoTi coted acetabular component
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 98 people
- Sponsor
- Hvidovre University Hospital
Delirium, Postoperative Complications
Postoperative Delirium in Hip Arthroplasty Patients
Identification of specific circulating microRNAs and microemboli formation (diagnosed by TC Doppler) in both delirious groups and nondelirious group will be our primary target.
- Trial name
- mRNAOrtho (NCT02323984)
- Testing
- miRNA Testing, Microemboli Monitoring, Delirium Assessment
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Ohio State University
Total Hip Replacements
An Exploration Into the Young Patients' (< 50 Years) Expectations Following Primary Total Hip Arthroplasty
This study seeks to explore between 6-7 patient participants' (18-50 years old inclusive) own expectations and hopes leading up to a THA, then to examine their own views on their recovery and rehabilitation post-operatively.
- Trial name
- YOUNG HIP (NCT04660149)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Bournemouth University
Osteoarthritis, Knee
A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty
The purpose of this research is to study how well the adductor canal pain catheters works after a total knee arthroplasty or replacement of the knee joint.
- Trial name
- NCT05053087
- Testing
- Ropivacaine Continuous Infusion, Ropivacaine Intermittent Bolus
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Knee Arthroplasty, Total, Osteoarthritis
Genicular Radiofrequency Ablation Efficacy in Achieving Total Knee Pain Reduction Trial
Given the benefits of genicular nerve radiofrequency ablation (RFA) in improving pain and functional status in non-surgical patients with knee osteoarthritis as well as the high prevalence of postoperative pain from total knee…
- Conditions
- Knee Arthroplasty, Total, Osteoarthritis, Radiologic Tibiofemoral Osteoarthritis
- Trial name
- NCT02947321
- Testing
- Genicular Nerve RFA
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vanderbilt University Medical Center
Knee Replacement Surgery
The Effect of Nasal Continuous Positive Airway Pressure (N-CPAP) on Arterial pCO2 During Spinal Anesthesia
The proposed study intends to investigate several aspects of the respiratory effects of intravenous sedation of patients undergoing spinal anesthesia for knee replacement surgery.
- Trial name
- NCT01622647
- Testing
- Nasal Continuous Positive Airway Pressure (NCPAP)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Pediatrix
Pain, Postoperative
Comparison of Outcomes Between Intraosseous Femoral and Tibial Injection in Simultaneous Bilateral Total Knee Arthroplasty Patients
In patients with osteoarthritis of the knee whose pain cannot be relieved by conservative treatment, total knee arthroplasty (TKA) is the operation that increases the quality of life for the patient.
- Trial name
- NCT06243575
- Testing
- Multimodal Intraosseous Femoral Injection, Multimodal Intraosseous Tibial Injection
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Arthroplasty, Replacement, Hip
Intraarticular Analgesia After Total Hip Arthroplasty, a Randomised Study
The purpose of this study is to determine whether wound infiltration with following single-shot bolus injection with local anesthetic and NASIDs are effective in the treatment of postoperative pain after total hip replacement…
- Trial name
- NCT00289419
- Testing
- Epidural Ropivacaine, morphine, Ropivacaine, Ketorolac and Adrenaline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Osteoarthritis, Knee, Patellofemoral Knee Arthroplasty
Study of Knee Replacements for Patellofemoral Osteoarthritis
This is a randomized comparison of PFA and TKR in treatment of isolated patellofemoral osteoarthritis.
- Trial name
- PFA/TKR (NCT01326156)
- Testing
- Knee arthroplasty
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Osteoarthritis
A Study on Rosa Roxburghii for Knee Replacement Recovery
This clinical trail is to investigates the effect of Rosa roxburghii juice freeze-dried powder on the recovery of patients undergoing total knee arthroplasty due to knee osteoarthritis.
- Trial name
- NCT07395856
- Testing
- Rosa roxburghii
- Volunteers
- 184 people
- Sponsor
- Shuguang Gao
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