Clinical trials: Arthroplasty, Replacement
Total Knee Arthroplasty
Analysis of Patient Outcome Questionnaire Following Primary Knee Replacement
The intention is to explore whether there are factors which help us to understand why some patient outcomes are not successful and identify prediction factors for progression.
- Trial name
- NCT03132077
- Testing
- total knee arthroplasty
- Where
- United Kingdom
- Volunteers
- 1,301 people
- Sponsor
- University of Salford
Spinal Anesthesia, Total Knee Replacement Arthroplasty
ED50 and ED95 of Intrathecal Bupivacaine With or Without Epinephrine for Total Knee Replacement Arthroplasty
This prospective randomized double-blind dose-response study is aimed to investigate the ED50 and ED95 of intrathecal bupivacaine with or without epinephrine 100 mcg for total knee replacement arthroplasty.
- Trial name
- NCT01264575
- Testing
- intrathecal bupivacaine 6 mg with 100 mcg of epinephrine, intrathecal bupivacaine 7 mg with 100 mcg of epinephrine, intrathecal bupivacaine 8 mg with 100 mcg of epinephrine
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Seoul Medical Center
Arthroplasty, Replacement, Hip
Secur-Fit Advanced Outcomes Study
The goal of this study is to evaluate the Secur-Fit Advanced Hip Stem in primary total hip replacement surgery.
- Trial name
- NCT01917929
- Testing
- Secur-Fit Advanced Hip Stem
- Where
- 8 sites in United States
- Volunteers
- 326 people
- Sponsor
- Stryker Orthopaedics
Revision Total Knee Replacement
Early Outcome Assessment of Revision Total Knee Arthroplasty Using Metaphyseal Sleeves
Metaphyseal sleeves, through their design, could allow reconstruction of the knee in cases of severe bone loss by allowing rigid internal fixation and proper alignment of the extremity and components.
- Trial name
- NCT01156558
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Knee
Zero Degree Knee Positioner for Improved Earley Knee Extension Following Total Knee Arthroplasty
Studies have demonstrated that early rehabilitation interventions following knee arthroplasty (TKA) can shorten the time needed to regain baseline extension/full extension and gait mechanics.
- Trial name
- NCT05678231
- Testing
- Zero Degree Knee Positioner
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Prisma Health-Midlands
Osteoarthritis
Assessment of Conventional and Patient-specific Instrumentation in Total Knee Arthroplasty
This study will use a special type of x-ray called radiostereometric analysis (RSA) imaging to determine whether patient-specific instrumentation for total knee arthroplasty (replacement) has an effect on implant loosening…
- Trial name
- NCT02230215
- Testing
- Total Knee Arthroplasty with use of Visionaire Patient-Specific Instrumentation
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Resistance Training, Stroke
The Effect of Isokinetic Strengthening Training
Our participants will include 40 patients within one month of stroke, 43 patients who received total hip replacement or total knee replacement two to four weeks before.
- Conditions
- Resistance Training, Stroke, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT02938416
- Testing
- Isokinetic strengthening exercise, Isotonic strengthening exercise, isometric strengthening exercise
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- Taichung Veterans General Hospital
Total Knee Arthroplasty
The Analgesic Effect of Nitroglycerin Patch for Postoperative Pain After Total Knee Replacement
Patients who undergo general anestheesia for total knee arthroplasty pften have sever postoperative pain which hinders their rehabilitation.
- Trial name
- NCT00375362
- Testing
- Nitroderm patch
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Arthroplasty, Replacement, Knee
Silkeborg Knee Replacement Cohort Study
In this cohort study, we will investigate short and long term outcomes after knee replacement surgery and identify preoperative and early postoperative factors associated with long term outcome.
- Trial name
- NCT03411083
- Testing
- Total or unicompartmental knee replacement
- Where
- Denmark
- Volunteers
- 1,225 people
- Sponsor
- Central Jutland Regional Hospital
Recovery Following Primary Total Knee Arthroplasty
Independent Exercise Compared With Formal Rehabilitation Following Primary Total Knee Replacement
In this study we plan to compare the efficacy of independent exercises performed by the patients at home to formal rehabilitation therapy following primary total knee replacement.
- Trial name
- NCT01826305
- Testing
- Formal Rehabilitation Therapy, Independent Exercise Cohort
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, San Francisco
Spinal Anesthesia, Total Knee Arthroplasty
Low Dose Spinal Bupivacaine for Total Knee Replacement and Recovery Room Wait Time
This study plans to investigate whether a reduced dose of bupivacaine (a local anesthetic numbing drug) injected into the spinal space for a total knee replacement will result in a shorter time to discharge from the recovery room…
- Trial name
- NCT00537472
- Testing
- Low dose bupivicaine in spinal anesthetic, Standard dose bupivacaine in spinal anesthetic
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Queen's University
Arthroplasty, Knee Replacement
The Effectiveness of Combined Care for Knee Replacement Patients
The goal of this clinical trial is to compare the effectiveness of combined care guidance and general care guidance on pain scores, anxiety levels and joint mobility in patients undergoing total artificial knee replacement.
- Trial name
- NCT06393075
- Testing
- combined care guidance, general care guidance
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Total Knee Replacement
Novel Strategies for Personalized Clinical Decisions in Knee Arthroplasty
This study will compare the postoperative recovery of two patient cohorts who attended outpatient physical therapy at two clinics in the Greenville, South Carolina area.
- Trial name
- NCT05900453
- Testing
- Clinical decision support (CDS) tool
- Where
- United States
- Volunteers
- 675 people
- Sponsor
- University of Colorado, Denver
Osteoarthritis, Knee
Conventional Alignment System Versus Surgical Navigation System in Total Knee Arthroplasty
This is a randomized, controlled, blinded prospective study comparing the use of the usual cutting guides with a palm-sized digital surgical navigation system in unilateral total knee arthroplasty.
- Trial name
- NCT01797731
- Testing
- Digital hand-held surgical navigation system, Conventional tibial extramedullary alignment system
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Replacement
The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement
Total knee replacement (TKR) is associated postoperatively with considerable pain and analgesic requirement. Total knee replacement is routinely performed under spinal anaesthesia with intrathecal bupivacaine plus preservative…
- Trial name
- NCT01312415
- Testing
- Levobupivacaine, Intrathecal morphine
- Where
- Ireland
- Volunteers
- 42 people
- Sponsor
- Cork University Hospital
Arthroplasty, Replacement, Shoulder, Arthritis Shoulder
Three Year Outcomes After Shoulder Arthroplasty
The purpose of this multicenter observational cohort study is to evaluate three-year outcomes in adults who underwent anatomic or reverse total shoulder arthroplasty using a contemporary shoulder implant system.
- Conditions
- Arthroplasty, Replacement, Shoulder, Arthritis Shoulder, Rotator Cuff Arthropathy
- Trial name
- NCT07815535
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Vani Sabesan
Arthroplasty, Total Hip Replacement
Radiological Measurement of Femoral Stem Version Using Lateral Decubitus Method: A Prospective Study
The purpose of this study was to develop a radiological method to measure stem anteversion and to determine its validity and reliability.
- Trial name
- NCT02554149
- Testing
- Radiological measurement of femoral stem version
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Bundang Hospital
Arthroplasty, Replacement, Shoulder
Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR)
The purpose of this study is to evaluate whether augmentation of subscapularis repair with the Regeneten implant after anatomic total shoulder arthroplasty (TSA) can improve rates of subscapularis healing and improve clinical…
- Trial name
- NCT04861714
- Testing
- Regeneten, Standard repair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ohio State University
Temporomandibular Disorders (TMD), Temporomandibular Joint Ankylosis
Virtual Planning of Total Temporomandibular Joint Replacement
A total TMJ replacement surgery is currently planned based on the X-ray appearance of the facial X-ray. It is now possible to use either an individually designed TMJ prosthesis or a prosthesis with a standard appearance.
- Trial name
- NCT07373184
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University Hospital
Arthroplasty, Replacement, Knee, Nerve Block
Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA
The purpose of this study is to determine if patients undergoing a Total Knee Arthroplasty who receive a single shot Adductor Canal nerve block and local infiltration will have improved functional outcomes compared to individuals…
- Trial name
- ACB (NCT02218814)
- Testing
- Adductor Canal Block, Bupivacaine, Femoral Nerve Block, Bupivacaine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- George Macrinici
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