Clinical trials: Arterial Stiffness, Blood Pressure
Sedentary Lifestyle, Blood Pressure
Blueberry Enhances Activity and Cognition Through Increased Vascular Efficiency
Recent evidence suggests that increased berry intake results in a variety of health benefits, across multiple health domains. This 3-month randomized, double-blind, placebo-controlled trial assess the effects of combining daily…
- Conditions
- Sedentary Lifestyle, Blood Pressure, Arterial Stiffness, Overweight and Obesity
- Trial name
- BEACTIVE (NCT04049162)
- Testing
- Blueberry Plus Exercise (BB-EX)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Duke University
Hypertension, Pre Hypertension
Breathing Exercises of CardioBreath Application on Autonomic and Vascular Function in Hypertension
Hypertension is one of the greatest public health challenges, affecting more than one billion people worldwide and representing a significant financial and public health burden.
- Trial name
- CardioBreath (NCT06917729)
- Testing
- CardioBreath
- Where
- 2 sites in Brazil
- Volunteers
- 66 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Essential Hypertension
Physical Activity, Air Pollution, and High Blood Pressure
The investigators are investigating the effects of traffic-related air pollution (TRAP) on the cardiovascular and pulmonary response to exercise in patients with hypertension using a real world randomized, crossover study design.
- Trial name
- NCT05092672
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of British Columbia
End-Stage Renal Disease
Vitamin D3 Supplementation in Dialysis Patients
Vitamin D deficiency is highly prevalent among dialysis patients, and has been associated with cardiovascular risk factors such as increased aortic pulse wave velocity, blood pressure, inflammation, and brain natriuretic peptide.
- Trial name
- NCT01312714
- Testing
- Cholecalciferol
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Regional Hospital Holstebro
Cardiovascular Risk Factor, Blood Pressure
Diurnal BP Patterns in Those at Increased Risk of CVD
In health, blood pressure (BP) falls at night by >10% compared with day-time values. This natural dipping pattern is important as without it there is an increased risk of cardiovascular disease (CVD).
- Conditions
- Cardiovascular Risk Factor, Blood Pressure, Arterial Stiffness, Chronic Kidney Diseases
- Trial name
- NCT04522765
- Testing
- Assessment of 24 hour blood pressure and arterial stiffness
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Healthy
Comparison of Dietary Fats on Vascular Parameters
The purpose of the study is to examine the effect of consuming 50g of fat from 5 different sources (coconut, canola, grapeseed, chia, and butter) on arterial stiffness, blood pressure and blood glucose levels.
- Trial name
- COIL (NCT01876394)
- Testing
- Coconut Oil, Canola Oil, Grapeseed Oil
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Hypertension
Blood Pressure Follow-up Study in Two Chinese Cohorts(C-BPCS)
Essential hypertension is a complex trait which results from interaction between environmental factors and genetic factors. The aim of this study is to investigate the effects of interaction between environmental factors and…
- Trial name
- C-BPCS (NCT02734472)
- Testing
- Incidence and risk factors of hypertension
- Where
- China
- Volunteers
- 5,298 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Primary Hypertension, Secondary Hypertension
HaemoDYNAMICs in Primary and Secondary Hypertension
The primary aim of the present study was to examine the haemodynamic changes in primary hypertension and secondary hypertension (renal diseases, endocrine diseases, obesity-associated hypertension) with a non-invasive…
- Conditions
- Primary Hypertension, Secondary Hypertension, Aortic Stenosis, Renal Insufficiency
- Trial name
- DYNAMIC (NCT01742702)
- Testing
- Nitroglycerin 0.25 mg (single dose, no longer given since January 2017), Salbutamol 400 µg (single dose, no longer given since January 2017), L-arginine (10 min infusion, no longer given since January 2017)
- Where
- 2 sites in Finland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tampere University
Prediabetes, Lipid Profile
How a Mediterranean Diet With Potatoes Impacts Heart and Metabolic Health in Adults With Pre-Diabetes
The goal of this clinical trial is to is to determine the effects of baked potato with the skin (BP) + nutrition education focused on adherence for a Mediterranean Dietary Pattern (MEDNE) on glycemic control, cardiometabolic…
- Conditions
- Prediabetes, Lipid Profile, Hypertension, Glycemic Control
- Trial name
- MEDPOT-PREDM (NCT06817252)
- Testing
- Mediterranean Diet Nutrition Education, Mediterranean Diet Nutrition Education with Baked White Potato
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Nevada, Las Vegas
End Stage Renal Disease, Peritoneal Dialysis
Relationship Between Blood Pressure and Pulse Wave Velocity Measurements in Peritoneal Dialysis
This study evaluates the relationship between Ambulatory Aortic and Branchial blood pressure vs Office blood pressure measurements with the changes in arterial stiffness indices, in long-term Peritoneal Dialysis (PD) patients.
- Conditions
- End Stage Renal Disease, Peritoneal Dialysis, Arterial Sclerosis
- Trial name
- NCT03607747
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Hypertension (Without Type 2 Diabetes Mellitus), High Blood Pressure
Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure
The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.
- Conditions
- Hypertension (Without Type 2 Diabetes Mellitus), High Blood Pressure, Male, Female
- Trial name
- NCT06735599
- Testing
- Wild Blueberry
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Georgia State University
Adenoma
Arterial Stiffness Index as a Predictor of Surgically Correctable Primary Aldosteronism
Our main objective is to assess whether aortic stiffness is a predictor of blood pressure response after surgery in patients with an aldosterone producing adenoma or a unilateral adrenal hyperplasia.
- Trial name
- NCT01190501
- Testing
- complier device
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Toulouse
Chronic Kidney Disease, Proteinuria
Sitaxsentan in Proteinuric Chronic Kidney Disease
Patients with chronic kidney disease (CKD) have higher blood pressures than the general population. They also tend to have protein leaking into the urine (proteinuria).
- Conditions
- Chronic Kidney Disease, Proteinuria, Blood Pressure
- Trial name
- NCT00817037
- Testing
- Sitaxsentan, Nifedipine
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Edinburgh
Kidney Transplantation
Impact of Arterial Stiffness and Central Aortic Blood Pressure on Kidney Transplant Outcomes
People with CKD have higher prevalence of cardiovascular disease. The mechanism behind this increased risk is complex but there is strong evidence that changes in arterial stiffness play a central role.
- Trial name
- NCT02000869
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Hypertension
International Registry for Ambulatory Blood Pressure and Arterial Stiffness Telemonitoring
This Registry is an investigator-initiated, international, multicenter, observational, prospective study aiming at: i) evaluating non-invasive 24-h ambulatory blood pressure and arterial stiffness estimates (through 24-h pulse…
- Trial name
- VASOTENS (NCT02577835)
- Testing
- Ambulatory blood pressure monitoring
- Where
- 24 sites in Argentina, Armenia and 8 more
- Volunteers
- 2,000 people
- Sponsor
- Italian Institute of Telemedicine
Type 1 Diabetes, Cardiovascular Complications
Vascular Complications in Children From T1D Diagnosis
Cardiovascular disease is a complication of type 1 diabetes (T1D), a life-long disease, usually diagnosed in childhood. The goal of this project is to determine the timing and factors leading to vascular damage in children from…
- Conditions
- Type 1 Diabetes, Cardiovascular Complications, Child, Adolescent
- Trial name
- NCT05790785
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of British Columbia
Arterial Hypertension
Physical Exercises Influence on Blood Pressure and Arterial Stiffness
Regular exercise is recommended as an adjuvant treatment in hypertensive subjects by both European and American guidelines. Crucially, however, there are no precise recommendations on the type of physical exercise and how it…
- Trial name
- NCT02844413
- Testing
- aerobic interval training
- Volunteers
- 60 people
- Sponsor
- Jagiellonian University
Arterial Stiffness, Blood Pressure
Korean Red Ginseng Rg3 Extract on Arterial Stiffness and Blood Pressure
The purpose of the study is to evaluate the acute effect of a standardized extract of KRG (Rg3-KRG) consisting of 30% total ginsenosides, including 10% Rg3 ginsenoside on arterial stiffness and blood pressure, as measured by the…
- Trial name
- KRAB (NCT01951443)
- Testing
- Ginseng, Wheat Bran
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Hypertension, Elderly
Predictive Values of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population
Introduction: High blood pressure especially systolic hypertension is a common condition in the elderly and is considered as a major determinant not only of cardiovascular (CV) morbidity and mortality, but also of several other…
- Conditions
- Hypertension, Elderly, Cardiovascular Mortality, Cognitive Impairment
- Trial name
- PARTAGE (NCT00901355)
- Where
- 6 sites in France, Italy
- Volunteers
- 1,130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France