Clinical trials: Arterial Pressure
Hypertension Complicated, Hypertrophy, Left Ventricular
Efficacy and Safety of Valsartan and Nebivolol/Valsartan in Hypertensive Patients With LVH
To assess the efficacy of Left Ventricular Hypertrophy (LVH) reduction and 24-hour blood pressure control of Valsartan 80mg or Nebivolol/Valsartan 5/80mg once daily as replacement therapy for currently treated or untreated…
- Conditions
- Hypertension Complicated, Hypertrophy, Left Ventricular, Blood Pressure
- Trial name
- BVreduce (NCT03180593)
- Testing
- Valsartan 80 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trinity Hypertension & Metabolic Research Institute
Overweight and Obesity, Pre-Diabetes
Stepping Into Lifestyle Changes
The purpose of this study is to promote healthy weight loss among African American women, age 30 or older, who are pre-diabetic and/or have high blood pressure and who live, work, or worship in select rural communities throughout…
- Conditions
- Overweight and Obesity, Pre-Diabetes, High Blood Pressure
- Trial name
- SILC (NCT05625321)
- Testing
- Educational Group Weight Loss Classes, Home Gardening Intervention
- Where
- 2 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Blood Pressure, Hypertension
Intervention With Riboflavin to Improve Vascular Health and ENdothelial Functioning in Genetically at- Risk Adults
High blood pressure is the leading risk factor for heart disease and stroke. Approximately 12% of the population have a particular genetic factor (known as the TT genotype) which increases the risk of high blood pressure.
- Trial name
- InteRVENE (NCT05488106)
- Testing
- Riboflavin 1.6mg/d, Riboflavin 5mg/d, Riboflavin 20mg/d
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Depression, Hypertension
Community-based Approach to Lowering Stress Through Mindfulness
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression.
- Trial name
- CALM-Chicago (NCT06987799)
- Testing
- Mindfulness-Based Stress Reduction (MBSR; CALM-Chicago Study)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Cardiovascular Diseases, Heart Diseases
Blood Pressure Tracking--Childhood to Young Adulthood
To extend analyses of blood pressure (BP) tracking to a period that spanned childhood and young adulthood. Data were used from the same cohort of 339 children who had been followed for nine to twelve years in a previous study.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005421
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension
Seasonal Variation of Ambulatory Blood Pressure
This is a prospective study to evaluate the change in 24 hour ambulatory blood pressure during winter and summer in well controlled treated hypertensives.
- Trial name
- NCT01119755
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- University of Athens
Hypertension, Cardiovascular Diseases
Effects of Cured Pork Peptides on Blood Pressure & Cardiovascular Risk Factors
Spanish dry-cured ham has been shown a source of antihypertensive peptides in mice. To date, no clinical study has been performed in humans to check the effects of bioactive peptides produced naturally during the processing of…
- Trial name
- PocPep-CVD (NCT02585089)
- Testing
- Spanish cured-pork ham, Cooked pork ham
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Resistant Hypertension
A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety
The goal of this clinical trial is to show the blood pressure lowering effect of aprocitentan, a new drug, when added to other anti-hypertensive drugs of patients with difficult to control (resistant) high blood pressure…
- Trial name
- PRECISION (NCT03541174)
- Testing
- Aprocitentan 12.5 mg, Aprocitentan 25 mg
- Where
- 159 sites in United States, Australia and 18 more
- Volunteers
- 730 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Right Heart Catheterization
The Nanowear Wearable System SimpleSense Validation Trial for Cardiac Output
The Nanowear SimpleSense study is a single center, prospective, non-randomized, feasibility, non- significant risk study The study will be done in 2 phases.
- Trial name
- NCT05629533
- Testing
- SimpleSense
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Nanowear Inc.
Hypertension
The Effect of Losartan and Losartan Plus Isosorbide Mononitrate on Central Blood Pressure Measurements (0954-317)
This study will qualify a functional model that can measure central blood pressure and vascular compliance effects through noninvasive means.
- Trial name
- NCT00943852
- Testing
- losartan potassium, Comparator: isosorbide mononitrate (ISMN), Comparator: losartan + ISMN
- Volunteers
- 13 people
- Sponsor
- Organon and Co
Childhood Cancer, Chronic Kidney Diseases
KIdney aNd blooD prESsure ouTcomes in Childhood Cancer Survivors (CCS)
Background: Childhood cancer survivors (CCS) are at elevated risk of chronic health conditions. Chemotherapies can cause recurrent acute kidney injury which may progress to kidney fibrosis, chronic kidney disease (CKD) or…
- Conditions
- Childhood Cancer, Chronic Kidney Diseases, Hypertension, Acute Kidney Injury
- Trial name
- KINDEST-CCS (NCT06153147)
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- The Hospital for Sick Children
Coronary Artery Disease., Aortic Valve Stenosis.
Cerebral Oxymetry at Elective Coronary and Valve Surgery.
Use of vasopressor to maintain Mean Arterial Pressure on Cardio Pulmonary Bypass can lead to decreased cerebral flow and oxygenation in individual patients and this can be detected by means of cerebral oxymetry.
- Conditions
- Coronary Artery Disease., Aortic Valve Stenosis., Aortic Valve Regurgitation.
- Trial name
- Co-HLM (NCT01940874)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Oslo University Hospital
Renal Insufficiency, Chronic, Hypertension
Supporting Self-Management of Healthy Behaviors in Diabetes, Kidney Disease, and Hypertension
The planned intervention, entitled, Supporting Self-Management of Health Behaviors to Optimize Health (SMART-HABITS for Health), aims to provide support for patients with chronic kidney disease (CKD), hypertension and diabetes by…
- Conditions
- Renal Insufficiency, Chronic, Hypertension, Diabetes
- Trial name
- NCT05565716
- Testing
- Support Person, Social Norms
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Pennsylvania
Blood Pressure
Adaptation and Implementation of a Cherokee-based Participatory Research Project to Reduce CVD Risk
This is a two phase project. Phase I is an online convenience sample to collect health and preference data for the intervention phase, as well as a partnership with community to co-create an intervention; Phase II.
- Trial name
- NCT06671652
- Testing
- Duyugoda igalenisodi (Starting again the right way)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Atherosclerosis
Aliskiren Effect on Aortic Plaque Progression
This study is being done to assess the effectiveness of short term (~9 months) Aliskiren/Placebo therapy to slow down the progression of atherosclerotic disease in thoracic and abdominal aorta.
- Trial name
- ALPINE (NCT01417104)
- Testing
- Aliskiren
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Ohio State University
Blood Pressure
Data Collection for Validation of an NIBP Algorithm in Pregnant Women
The purpose of the study is to collect per subject blood pressure data on the device's intended population as described in the International Organization for Standardization (ISO) Standard 81060-2:2018+A1:2020 Non-invasive…
- Trial name
- NCT05789849
- Testing
- Collecting blood pressure measurements with noninvasive blood pressure device
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- GE Healthcare
End Stage Renal Disease
Central Blood Pressure and Pulse Wave Velocity in Kidney Transplant Recipients
An observational cohort study will be conducted to non-invasively investigate central blood pressure and pulse wave velocity in children with kidney disease and controls.
- Trial name
- NCT04212143
- Testing
- there is no intervention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's National Research Institute
Blood Pressure
Study on Pressure Values Measured on Three Alternative Sites of the Lower Limbs Compared to the Arm
Non-invasive measurement of blood pressure is an instrument governed nursing routine care. The use of an automated oscillometric cuff is a common technique and validated if this is done on the arm with a suitable cuff, positioned…
- Trial name
- VALPARAISO (NCT02529735)
- Testing
- efficiency study
- Where
- 8 sites in France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Sud Francilien
Hypertension
Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)
Nitroprusside is used commonly in the Intensive Care Unit for long periods of time in order to reduce blood pressure. It is not known if the body compensates over time to the blood pressure lowering, and if when the nitroprusside…
- Trial name
- NCT00621816
- Testing
- nitroprusside
- Where
- 8 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hypertension
SPP100 (Aliskiren) Regimen in Patients With Severe Hypertension
Assessing the safety and efficacy of SPP100 (Aliskiren) regimen in patients with severe hypertension
- Trial name
- NCT00299806
- Testing
- Aliskiren
- Where
- Japan
- Volunteers
- 39 people
- Sponsor
- Novartis