Clinical trials: Arterial Hypotension
Surgery
Permissive Hypotension After Cardiac Surgery
The objective of this pilot randomized controlled trial is to demonstrate the feasibility of implementing a pragmatic clinical trial randomizing patients to permissive hypotension versus usual care and to determine the impact of…
- Trial name
- PHACS (NCT06476613)
- Testing
- Permissive Hypotension
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Hypotension
Early Prediction of ICU Hypotension Using Machine Learning
This prospective observational study aims to develop and internally validate a machine learning model for the early prediction of hypotension in adult intensive care unit patients.
- Trial name
- ICU-HypoAI (NCT07627607)
- Testing
- Routine ICU Data Collection
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kutahya Health Sciences University
Hypotension, Ischemia
Phase III Study of Hemospan® for Treating Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for treatment of hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and…
- Trial name
- NCT00420277
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 22 sites in Belgium, Czechia and 3 more
- Volunteers
- 462 people
- Sponsor
- Sangart
Hypotension, Hypoxemia
Point of Care Ultrasound Evaluation in the Post-Anesthesia Unit
The purpose of this observational research study is to examine how point-of care ultrasound affects the workup and management of perioperative complications for specific clinical scenarios of low blood pressure (hypotension), low…
- Conditions
- Hypotension, Hypoxemia, Altered Mental Status, Urine Output Low
- Trial name
- NCT04410757
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Loma Linda University
Hypotension
HFR A-equilibrium on Cardiovascular Stability
Aim of the present randomized controlled multinational trial is the comparison of a novel biofeedback system on sodium profiling applied to a endogenous hemodiafiltration therapy, with the standard (no sodium profiling)…
- Trial name
- AIMS (NCT01414842)
- Testing
- Automated sodium profiling in endogenous hemodiafiltration, Standard sodium dialysate
- Where
- 12 sites in Belgium, France and 3 more
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera di Lecco
Hip Disease, Hypotension
Hypotension Probability Index in Anesthesia
The aim of the study is to investigate the value of the Hypotension Probability Index in reducing intraoperative hypotension in patients with primary hip replacement.
- Conditions
- Hip Disease, Hypotension, Surgery, Anesthesia
- Trial name
- NCT03663270
- Testing
- Hypotension probability index (HPI)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Giessen
Caesarean Section
The Pleth Variability Index and Hypotension at Caesarean Under Spinal.
During a caesarean section the blood pressure is usually measured every few minutes and it may fall too quickly to be detected in a timely fashion by this intermittent means.
- Trial name
- NCT02285569
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Post Operative Pain, Bradycardia
Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
To compare the immediate and postoperative analgesic efficacy of S-FICB and PENG block will be the objective. The use of ultrasonography in anesthesia has helped the anesthetist to see the nerve, needle and the distribution of…
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Femur Fracture
- Trial name
- NCT06568770
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sahiwal medical college sahiwal
Labor Pain, Analgesia, Epidural
A Study on the Effect of Position on Walking Labour Epidural Efficacy
This study is being done to better understand how patient positioning can affect pain relief after an epidural. In addition to pain, the investigators will assess how position affects epidural spread, and its effects on maternal…
- Trial name
- NCT04469101
- Testing
- Lumbar Epidural
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia
The purpose of this study is to investigate the efficacy and safety of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556357
- Testing
- Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypotension Drug-Induced, Cesarean Section Complications
Spinal Anesthesia in Caesarean Section
Spinal anesthesia is a safe technique, widely used and tested in the gynecological field, so as to be considered the first choice technique in cesarean section, which allows to quickly obtain a valid sensor and motor block.
- Conditions
- Hypotension Drug-Induced, Cesarean Section Complications, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Bradycardia
- Trial name
- NCT03743870
- Testing
- Levobupivacaine, Bupivacaine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele
Hypotension During Surgery
Study on the Safety and Effectiveness of Remimazolam Tosilate for Injection for Short-term Elective Surgery in Adults
Research objective: To explore the safety and dose exploration of Remimazolam Tosilate for Injection for induction and maintenance of general anesthesia in elective short-term surgery in adults.
- Trial name
- NCT04908553
- Testing
- Remimazolam Tosilate for Injection 0.1mg/kg, Remimazolam Tosilate for Injection 0.15mg/kg, Remimazolam Tosilate for Injection 0.2mg/kg
- Where
- China
- Volunteers
- 650 people
- Sponsor
- Tongji Hospital
Spinal Hypotension, Vasopressor
Caffeine and Prophylactic Noradrenaline Requirement During Cesarean Delivery
Spinal anesthesia is the preferred regional technique in obstetric practice because it provides high maternal satisfaction and eliminates the need for airway manipulation.
- Trial name
- NCT07655245
- Testing
- Caffeine (200 mg)
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Cairo University
Post-Dural Puncture Headache, Hypotension
Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section
The goal of this clinical trial is to compare different approaches of spinal anesthesia in pregnant females who are having cesarean section.
- Conditions
- Post-Dural Puncture Headache, Hypotension, Spinal Shock, Hematoma
- Trial name
- NCT05637645
- Testing
- Midline Approach, Paramedian Approach, Taylors approach
- Where
- 4 sites in Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bahawal Victoria Hospital Bahawalpur
Shy-Drager Syndrome, Multiple System Atrophy
Water and Sudafed in Autonomic Failure
The specific aim of this study is to determine whether water ingestion potentiates the pressor response to pseudoephedrine in patients with primary disorders of autonomic failure.
- Trial name
- NCT02149901
- Testing
- Pseudoephedrine + 480 ml water, Pseudoephedrine + 50 ml water
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Vanderbilt University
Orthostatic Hypotension, Falls
Orthostatic Hypotension Treatment on Rehab Unit
For patients recovering from acute illness, the ability to stand, walk, climb stairs, and participate in therapy are critical to their recovery and eventual discharge to the least restrictive environment.
- Trial name
- NCT01030874
- Testing
- Medication review, Nutrition/Salt intake, Education
- Where
- United States
- Volunteers
- 356 people
- Sponsor
- VA Office of Research and Development
Hypotension, Cesarean Section
Comparison of Hypotension During Spinal Anaesthesia for C-section
Maternal hypotension during C section has been reported due to aortocaval compression (ACC) by full term uterus in supine position. This study aimed at reporting the effect of left tilt on maternal hemodynamics.
- Conditions
- Hypotension, Cesarean Section, Aortocaval Compression
- Trial name
- NCT05427968
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Rawalpindi Medical College
Hemodialysis Complication
Coffee in Hemodialysis and Headache
Coffee is the most consumed drink worldwide, sometimes needed to boost energy and other times to entertain social connectivity. Caffeine is mostly present unbound in the plasma, only 10 to 30% of caffeine binds to plasma…
- Trial name
- CoffeeHD (NCT04057313)
- Testing
- Coffee
- Where
- Lebanon
- Volunteers
- 156 people
- Sponsor
- Saint-Joseph University
Anesthesia, Hypotension
Preoperative Ultrasound-based Protocol for Optimization of Fluid Therapy to Prevent Early Intraoperative Hypotension
Background: Intraoperative hypotension increases 30-day mortality and the risks of myocardial injury and acute renal failure. Patients with inadequate volume reserve before the induction of anesthesia are highly exposed.
- Conditions
- Anesthesia, Hypotension, Lung Ultrasound, Echocardiography
- Trial name
- NCT05171608
- Testing
- Ultrasound-based protocol based fluid therapy
- Where
- Hungary
- Volunteers
- 80 people
- Sponsor
- Semmelweis University
Hypotension in Pregnant Women, Headache in Pregnant Women
Prediction of Hypotension and Postdural Puncture Headache by Carotid Artery Corrected Flow Time
Anesthesia for cesarean delivery can be provided through general or neuraxial anesthesia (spinal or epidural). Hypotension is a common complication of both methods.
- Trial name
- NCT07372313
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
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