Clinical trials: Arm Paralysis
Stroke, Hemiparesis
Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke
To determine whether treatment with transauricular vagus nerve stimulation (taVNS) during the training of an affected upper limb of a patient with chronic stroke on a robotic motor task alters the motor impairment.
- Trial name
- VaNSaRTS (NCT05339893)
- Testing
- In Motion Rehabilitation Robot
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Hemiplegic Cerebral Palsy
Sensorimotor Training and Constraint Induced Movement Therapy on Upper Extremity Function in Children With Hemiplegic CP
The aim of the work was to find out the effects of sensorimotor training and constraint induced movement therapy on upper extremity function in children with hemiplegic cerebral palsy.
- Trial name
- NCT05490758
- Testing
- sensorimotor training, constraint induced movement therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Unilateral Spastic Cerebral Palsy
"Be an Airplane Pilot": A Bimanual 3D Motion Analysis in Children With Unilateral Cerebral Palsy
Cerebral Palsy, in particular in its unilateral spastic form (uCP), is the main cause of motor disability in children, with a prevalence of 2/1000 births.
- Trial name
- BE-API (NCT03888443)
- Testing
- Bimanual 3D Motion Analysis " Be-API "
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Cerebral Palsy, Children With Brain Injury
The Effect of Digital Rehabilitation System With Wearable Multi-IMU (Inertial Measurement Unit) Sensors on Upper Limb Functions in Children With Brain Injury
This study was designed to establish the clinical evidence for effect of video-game based rehabilitation therapy system using IMU sensors as a game interface, newly-developed in Korea, on upper limb function of children with…
- Trial name
- NCT02949817
- Testing
- digital rehabilitation system with wearable multi-IMU(inertial measurement unit) sensors (Rapael kids), Conventional OT group
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Stroke, Hemiplegia
Combined Robotic Hand Rehabilitation and Conventional Rehabilitation for Post-stroke Rehabilitation
Objective: The investigators compared the effectiveness of individual and combined application of conventional rehabilitation and robotic hand rehabilitation in post-stroke hemiplegia.
- Trial name
- NCT06184191
- Testing
- Robotic hand rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Hemiplegic Cerebral Palsy
Action Observation Versus Mirror Therapy in Children With Spastic Hemiplegic Cerebral Palsy
The goal of this clinical trial is to compare the effects of Action Observation therapy and Mirror therapy on hand grip strength and upper extremity function in children with hemiplegic cerebral palsy.
- Trial name
- NCT07739069
- Testing
- Mirror Therapy, Action Observation Therapy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Cerebral Palsy, Diplegic Cerebral Palsy
The Relationship Between Upper Extremity Functionality, Trunk Control and Balance in Children With Cerebral Palsy
The aim of this study is to examine the relationship between trunk control, upper extremity functionality and balance in children with cerebral palsy and to compare this relationship with healthy sedentary children.This study is…
- Conditions
- Cerebral Palsy, Diplegic Cerebral Palsy, Balance; Distorted
- Trial name
- NCT06378723
- Testing
- Balance Tests
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Neurological Injury, Hemiplegia
Camp High 5: Evaluation of the Effect on Upper Limb Function
Randomized control trial to evaluate uni-manual and bimanual upper limb function as well as compare outcomes of varied cast wear in children with hemiplegic cerebral palsy (CP) following a hybrid camp model of modified constraint…
- Trial name
- NCT02875054
- Testing
- Constraint induced movement therapy (CIMT), Hand-arm bimanual intensive training (HABIT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
Tetraplegia, Spinal Cord Injuries
Nerve Transfer After Spinal Cord Injury- Multi-center
Current treatment strategies of acute cervical spinal cord injuries remain limited. Treatment options that provide meaningful improvements in patient quality of like and long-term functional independence will provide a…
- Conditions
- Tetraplegia, Spinal Cord Injuries, Quadriplegia Flaccid
- Trial name
- NCT04023591
- Testing
- Surgery/Occupational Therapy
- Where
- 9 sites in United States, Canada
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Cerebral Palsy
Effect of HABIT-ILE on the Body Function and Structures of Children With Cerebral Palsy
There is strong evidence that recent intensive interventions based on motor skill learning principles are efficient on functional and neuroplastic changes of children with cerebral palsy (CP).
- Trial name
- NCT04403490
- Testing
- HABIT-ILE, Conventional intervention
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Université Catholique de Louvain
Neurological Rehabilitation, Stroke
Evaluation of Hand Strength and Spasticity in Hemiplegic Patients
The aim in this study is to evaluate spasticity and hand grip strength with a finger hand robot in the Turkish population.
- Conditions
- Neurological Rehabilitation, Stroke, Upper Extremity Problem
- Trial name
- NCT05662878
- Testing
- Assessment of Hand Strength and Spasticity
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Cerebral Palsy, Hemiplegic Cerebral Palsy
The Effect of Music Therapy on Upper Extremity Functions and Quality Of Life in Individuals With Cerebral Palsy
The main purpose of this study is to investigate the effect of music therapy on the upper extremity functions and quality of life of individuals with Cerebral Palsy (CP).
- Conditions
- Cerebral Palsy, Hemiplegic Cerebral Palsy, Music Therapy
- Trial name
- NCT06209840
- Testing
- Control Group, Study (Music) Group
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Ankara Yildirim Beyazıt University
Hemiparetic Cerebral Palsy
Using Neurotechology to Help Children With Physical Disability Due to Cerebral Palsy
Hemiparetic cerebral palsy is a condition in which one side of a child's body becomes weak due to brain injury occurring around birth, often caused by stroke.
- Trial name
- NCT07269353
- Testing
- Brain Computer Interface - Functional Electrical Stimulations
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Stroke, Hemiplegia
Tele-rehabilitation in the Home With Gaming as a Method of Improving Upper Extremity Function After Stroke
The purpose of the study is to determine whether a novel computer gaming hand exercise regimen would improve hand and arm function and be feasible in people with hemiplegia after Stroke affecting the hand.
- Trial name
- NCT02494362
- Testing
- Computer gaming hand exercise regimen.
- Where
- 2 sites in Canada
- Volunteers
- 15 people
- Sponsor
- University of Manitoba
Spastic Hemiplegic Cerebral Palsy
Modified Constraint-Induced Movement Therapy in Children With Hemiparetic Cerebral Palsy
Cerebral palsy (CP) is defined as a non-progressive lesion of the developing foetal or infant brain and causes variety of motor, sensory and cognitive impairments.
- Trial name
- NCT04064788
- Testing
- Consecutive Modified Constraint-Induced Movement Therapy, Traditional physiotherapy, Intermittent Modified Constraint-Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy
Functional Effects and Impact on Motor Neuronal Activity of Early and Intensive Motrice (Hand and Arm Bimanual Intensive Therapy Including Lower Extremities: HABIT-ILE) Reeducation in Children With Pre-school Bilateral Cerebral Palsy
One of the urgent priorities in the field of pediatric neuro-rehabilitation is the development of efficient early motor interventions for children with cerebral palsy (CP).
- Trial name
- MOOV (NCT04362800)
- Testing
- MRI, Electro-Encephalography-High Density, 3D and EMG analysis
- Where
- 2 sites in France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Brest
Stroke, Ischemic, Stroke Hemorrhagic
Utility of CC7 Transfer in Stroke Subtypes
The purpose of this study is to evaluate the limb functional improvement after contralateral C7 root transfer in stroke patients.
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Spastic Hemiparesis
- Trial name
- NCT06001736
- Testing
- Contralateral C7 root transfer for the treatment of spastic hemiparesis.
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hereditary Spastic Paraplegia Type 50
Phase 3 Efficacy Study With Concurrent Control of IT MELPIDA in SPG50.Concurrent Controls.
Phase 3, open-label study to assess the efficacy and safety of a single lumbar intrathecal administration of MELPIDA in individuals with Hereditary Spastic Paraplegia Type 50 (SPG50).
- Trial name
- SPG50 (NCT06692712)
- Testing
- MELPIDA
- Where
- 2 sites in United States, Spain
- Volunteers
- 24 people
- Sponsor
- Elpida Therapeutics SPC
Cerebral Palsy Spastic Hemiplegic
tSCS in Children and Young People With HCP
This work will examine if a technique called Transcutaneous Spinal cord stimulation (tSCS), when used with concurrent specific arm and hand exercises, helps improve arm and hand movements in CYP with HCP.
- Trial name
- NCT07247812
- Testing
- Digimer DS8R
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Leeds
Stroke, Hemiplegia
Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction
Upper limb paralysis following stroke is a very common problem. Only 30% of stroke patients who suffer from upper limb paresis experience a full recovery of function.
- Trial name
- VibMirror (NCT01010607)
- Testing
- Vibration and Mirror, Mirror therapy
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization