Clinical trials: Appropriateness
Chronic Low Back Pain, Chronic Neck Pain
RAND Center of Excellence for the Study of Appropriateness of Care in CAM
The RAND approach to appropriateness makes it feasible to take the best of what is known from research and apply it-using the expertise of experienced clinicians-over the wide range of patients and presentations seen in…
- Trial name
- CERC (NCT03162952)
- Where
- United States
- Volunteers
- 2,025 people
- Sponsor
- RAND
Peripheral Venous Catheter
Assessing the Effect of Staff Education on Unused Peripheral Venous Catheter Rates in Emergency Departments.
The placement of peripheral venous catheters (PVC) is a common procedure, estimated at 25 million per year in France according to SF2H in 2005.
- Trial name
- ED-Cath 2 (NCT07449455)
- Testing
- Medical staff educational intervention
- Where
- France
- Volunteers
- 516 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patients Under Antimicrobial Therapy
Impact of Infectious Diseases Specialists on the Appropriateness of Antimicrobial Therapy in Emergency Wards
CONTEXT: Antibiotics are frequently used in hospital but the appropriateness of prescriptions ranged between 25-50%. The intervention of infectious disease specialists (IDS) could improve the appropriateness of prescriptions and…
- Trial name
- ATBREFEMERG (NCT01137864)
- Testing
- Infectious disease specialist advice
- Where
- France
- Volunteers
- 255 people
- Sponsor
- Henri Mondor University Hospital
HIV, PrEP
The ACT-PrEP Study
AIM: To evaluate the integration of point-of-care etiological STI testing, cognitive behavioral counselling (CBC), and sexual partner engagement strategies to improve STI management, PrEP uptake and 3-month PrEP persistence among…
- Conditions
- HIV, PrEP, Acceptability, Appropriateness
- Trial name
- NCT07867990
- Testing
- POC STI testing, CBC, and partner self-testing to improve PrEP uptake and persistence among pregnant and postpartum women., Standard of Care
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Children,Hospitalized, Vascular Access Devices
Implementation and Evaluation of the Selection Scheme of Peripheral Venous Infusion Devices for Hospitalized Children
This study is a stepped wedge cluster randomized trial design. The object is to evaluate the influence on patient outcomes, medical staff's evidence-based practice behavior and hospital context after implementation of the…
- Trial name
- NCT05378568
- Testing
- the selection scheme of peripheral venous access devices, the existing nursing routine
- Where
- China
- Volunteers
- 4,652 people
- Sponsor
- Children's Hospital of Fudan University
Acquisition of Literacy Skills for All Children, Including Those With SLDs, Appropriateness of Referrals for SLD Assessment for Accurate Early Detection of SLDs
Literacy Skills Improvement and Early Diagnosis of Specific Learning Disorders (SLD) Using a New Phono Syllabic Program
Scientific evidence shows that systematic phonological approaches are more effective than other methods in teaching children to read and should therefore be adopted in schools.
- Trial name
- ALFABETO (NCT07510126)
- Testing
- Alfabeto program, Other literacy teaching methods
- Where
- Italy
- Volunteers
- 1,407 people
- Sponsor
- IRCCS Burlo Garofolo
Inappropriate Prescribing, Primary Health Care
Deprescribing in Primary Health Care
Medications can help older adults but can also harm them. Frail older adults tend to have many health problems that require treatment, but are also at risk of harm from the medications prescribed.
- Conditions
- Inappropriate Prescribing, Primary Health Care, Polypharmacy
- Trial name
- NCT03903484
- Testing
- Deprescribing toolbox and intervention
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Healthy
Prevention of Potentially Inappropriate Prescribing in Late Life Using Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP) and Screening Tool to Alert Doctors to Right Treatment (START) Criteria
Potentially inappropriate prescribing is common in older patients and encompasses overuse, misuse and underuse of medications. Potentially inappropriate prescribing is associated with negative outcomes including adverse drug…
- Trial name
- NCT00915824
- Testing
- STOPP/START criteria
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
Behavior Problem, Behavior, Child
Effectiveness of an Online Parenting Training
Child and adolescent behavioral health problems are related to the leading causes of youth morbidity and mortality. Parent-focused preventive interventions, such as GenerationPMTO (GenPMTO), effectively prevent behavioral health…
- Conditions
- Behavior Problem, Behavior, Child, Parents, Parent-Child Relations
- Trial name
- NCT05111886
- Testing
- Communication Skills Training, eHealth GenPMTO, Written Referral Process
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Endometrial Cancer
Trial Between Two Follow up Regimens With Different Test Intensity in Endometrial Cancer Treated Patients
This study aims to compare two different follow up regimens with different test intensity in endometrial cancer treated patients.
- Trial name
- TOTEM (NCT00916708)
- Testing
- Intensive/Low-Risk follow up (IA G1; IA G2), Intensive/High-Risk follow up (≥ IA G3), Minimalist/Low-Risk follow up (IA G1; IA G2)
- Where
- Italy
- Volunteers
- 1,884 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms
Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails
Opioid overdose is the leading cause of death among people recently released from incarceration. Recent evidence also shows a rise in stimulant use among justice-involved populations, as well as growing rates of concurrent opioid…
- Conditions
- Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder
- Trial name
- HOPE (NCT07490717)
- Testing
- Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- University of Arkansas
Appropriate Startup of Acid Suppressive Therapy
Acid Suppressive Therapy - Review of Appropriateness
Acid suppressive therapy (AST) is used in a variety of indications in prevention and treatment of gastric acid related disorders. In recent years, an increase in the use of acid suppressive therapy has been documented.
- Trial name
- ASTRA (NCT02259270)
- Testing
- Record review, AST-history
- Where
- Belgium
- Volunteers
- 600 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Inguinal and Ventral Hernia Repair by Sublay, Underlay and IPOM Mesh Fixation
Effectiveness, Appropriateness and Safety of GLUTACK-Glubran Tiss 2 Surgical Glue Compared to GLUTACK-Glubran 2 Device System for Mesh Fastening in Laparoscopic and Robotic Hernia Surgery
This pre-market, prospective, randomized, non-inferiority clinical study was designed to evaluate the safety and performance/effectiveness of Glutack-Glubran® Tiss 2 system compared to Glutack-Glubran® used for mesh fixation in…
- Trial name
- AGluTHeMFix (NCT06462066)
- Testing
- Experimental medical device, Comparator medical device
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- GEM SRL
Colorectal Cancer Control and Prevention
Appropriateness of Colonoscopy Indication: an Evaluation of the Clinical and Economic Impact.
The aim of the study is to evaluate the appropriateness of colonoscopy prescription and the impact of colonoscopies in diagnostic performance in order to develop and validate a predictive model for selecting patients most likely…
- Trial name
- PROMOTE (NCT06775951)
- Where
- 2 sites in Italy
- Volunteers
- 1,410 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Severe Mental Illness, Schizophrenia
Reduction of Cardiovascular Risk in Severe Mental Illness
Background: Patients with severe mental illness (SMI) have a higher prevalence of cardiovascular risk factors (CVRF) than the general population and a control of these risk factors poorer.
- Conditions
- Severe Mental Illness, Schizophrenia, Bipolar Disorder, Affective Disorders
- Trial name
- RISCA-TMS (NCT01182012)
- Testing
- Lifestyle counseling
- Where
- Spain
- Volunteers
- 391 people
- Sponsor
- Consorci Hospitalari de Vic
Heart Failure
Drug Management in Heart Failure
Aim of the proposal is to create an interactive AI-based multicentre prospective database to provide information on how to improve the QoC for pts with HF.This will provide detailed information on pts characteristics,treatment…
- Trial name
- DRUM-HF (NCT06915584)
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- IRCCS San Raffaele Roma
Cardiac Arrest, Out-Of-Hospital
Validity of ICU Clinician's Appraisal of Proportionality in CPR
The VICAP-CPR study investigates whether doctors and nurses working in Intensive Care can determine neurological outcome and future quality of life after six months in patients treated for cardiac arrest outside the hospital…
- Trial name
- VICAP-CPR (NCT07026773)
- Where
- 9 sites in Austria, Belgium and 6 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Excessive Amount of Blood / Fluid Transfusion
Blood Management Program in the Post - Operative Period.
A care path in the field of transfusion medicine was creates at ASMN - IRCCS addressed to patients undergoing complex surgical procedures.
- Trial name
- NCT02149069
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Elderly (People Aged 65 or More), Polypharmacy (People Under Treatment With 5 or More Drugs)
Inappropriate Prescription in Elderly and Polypharmacy Patients in Primary Care (PHARM-PC) Trial
PHARM-PC study is based on identify potentially inappropriate prescriptions (PIP) and delivery therapeutic appropriateness recommendations from the pharmacist to the physician and about drugs prescribed for elderly and…
- Trial name
- PHARM-PC (NCT02224833)
- Testing
- Pharmacist intervention
- Where
- Spain
- Volunteers
- 549 people
- Sponsor
- Hospital Comarcal de Inca
Depression in Adults
Pilot Study of Brief Culturally Adapted Behavioral Activation for Adults With Depression in Primary Care Setting
This is a pilot study of culturally adapted behavioral activation for adults with depression in primary care setting. As a pilot study following systematic cultural adaptation process, the purpose of this clinical trial is to…
- Trial name
- NCT07120893
- Testing
- brief culturally adapted behavioral activation
- Where
- Indonesia
- Volunteers
- 12 people
- Sponsor
- Gadjah Mada University