Clinical trials: Appetite Regulation, open to volunteers
Overweight
Physical Inactivity and Appetite Regulation
The goal of this parallel-group, two-arm, assessor-blinded, randomised clinical trial is to investigate the effects of reducing physical activity on food intake and satiety in physically active and healthy males, 40-55 years of…
- Trial name
- NCT06240208
- Testing
- Inactivity
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Obesity, Childhood
Development of an Eating Behavior Risk Score
This study will explore how children's eating behaviors are connected to brain activity and body fat levels. Researchers are especially interested in a behavior pattern called the PACE phenotype, which includes how much children…
- Trial name
- PACE (NCT07266506)
- Testing
- Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Penn State University
Appetite Regulation, Healthy Young Adults
Satiety Evaluation of Mature Okra Flour-incorporated Biscuit
This study aims to evaluate whether eating biscuits made with mature okra flour can help young adults feel fuller (enhance satiety) and change certain blood markers compared to eating standard biscuits.
- Trial name
- MOFB (NCT07631663)
- Testing
- Mature Okra Flour-incorporated Biscuit (MOFB), Control Biscuit
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Glycemic Response to Feeding in Healthy Participants, Postprandial Amino Acid Concentrations
Comparison of Dairy and Plant-based Alternatives in Adolescents and Older Adults
The purpose of the Dairy vs Plant study is to compare the effects of dairy and plant-based alternative products on blood sugar regulation and nutrient quality in adolescents and older adults.
- Conditions
- Glycemic Response to Feeding in Healthy Participants, Postprandial Amino Acid Concentrations, Appetite Regulation
- Trial name
- NCT06874400
- Testing
- Dairy, Plant-based alternative
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity & Overweight, Cardiometabolic Health Indicators
Tirzepatide Impact Assessment Study
This study examines how two different weight-loss strategies affect heart and metabolic health, as well as changes at the molecular level in the body.
- Conditions
- Obesity & Overweight, Cardiometabolic Health Indicators, Addiction, Eating Disorders
- Trial name
- TIA (NCT07740291)
- Testing
- GLP-1 Receptor Agonist Therapy, Structured Lifestyle Intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Energy Balance, Physiology - Regulation of Appetite and Food Intake
The Role of Estradiol and Progesterone on Appetite Regulation and Energy Balance
The goal of this study is to determine if estradiol and progesterone are involved in appetite regulation and energy balance. The study aims to complete a 13 day randomized controlled trial (RCT) where oral supplementation of…
- Trial name
- E2 & P4 in EB (NCT07620587)
- Testing
- Estradiol Only, Progesterone Only, Estradiol and Progesterone Combination
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wilfrid Laurier University
Healthy, Overweight (BMI > 25)
Effect of Probiotics on Appetite Regulation in Adults With Overweight/Obesity
The goal of this 16-week randomised, placebo-controlled parallel study is to investigate the effect of a newly formed probiotic supplement on satiety and gut microbiota composition in healthy men and women with overweight or…
- Conditions
- Healthy, Overweight (BMI > 25), Overweight , Obesity, Male
- Trial name
- ProBiSat (NCT07715955)
- Testing
- Probiotic supplementation
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Malnutrition Elderly, Protein Malnutrition
The Effect of a Plant-based, Protein-dense Sauce on Essential Amino Acid Concentrations and Gut Fullness in Older Adults
The goal of this clinical trial is to determine whether meals fortified with plant-based high protein sauce (ProSauce) provide better metabolic availability of essential amino acids compared to meals with standard lower-protein…
- Trial name
- ProSauce (NCT06965699)
- Testing
- ProSauce, low-protein sauce
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Energy Balance, Energy Expenditure
Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females
There is growing evidence that males and females may exhibit different acute responses and long-term adaptations to exercise training.
- Conditions
- Energy Balance, Energy Expenditure, Males and Females, Resistance Exercise
- Trial name
- NCT07444021
- Testing
- resistance exercise (males), resistance exercise (females)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Obesity, Emotional Eating
Evaluation of Anhedonia and Emotional Eating in Individuals Using GLP-1 Receptor Agonists
This prospective observational study evaluates the longitudinal changes in anhedonia levels and emotional eating behaviors among adult individuals initiating glucagon-like peptide-1 (GLP-1) receptor agonist therapy for weight…
- Conditions
- Obesity, Emotional Eating, Anhedonia
- Trial name
- NCT07803185
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Obesity (Disorder), Weight Change
Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination
Semaglutide is a medication from the class of drugs called glucagon-like peptide-1 agonists that promote weight loss. There is little clinical data on the best strategy to achieve weight maintenance following weight reduction…
- Conditions
- Obesity (Disorder), Weight Change, Blood Pressure Monitoring, Appetite Regulation
- Trial name
- REST (NCT07294950)
- Testing
- Gradual dose reduction of semaglutide, Abrupt cessation of semaglutide
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- Mount Sinai Hospital, Canada
Type 2 Diabetes Mellitus
Incretin Therapy and Exercise in Type 2 Diabetes
This study will examine changes in brain and physical health in adults with type 2 diabetes who are initiating incretin-mimetic therapy (e.g., Ozempic, Mounjaro), and determine whether adding structured exercise provides…
- Trial name
- BIOM (NCT07833813)
- Testing
- Structured Exercise Program
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- University of Regina
Healthy Participants, Healthy Adult Subject
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Acute Postprandial Study
The goal of this clinical trial is to learn how eating different snack foods affects acute hunger, energy intake and eating behaviour in healthy adults. The study will be conducted remotely over 5 days.
- Conditions
- Healthy Participants, Healthy Adult Subject, Healthy Subjects, Healthy Adult Volunteer
- Trial name
- SMARTEATS-PP (NCT07776418)
- Testing
- High-fibre plant-based snack bar, Control snack bars
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Obesity & Overweight, Metabolic Disorders
Diet and WB-EMS Effects in Obesity
Obesity is a major global health problem associated with metabolic dysfunction, altered adipokine signaling, and impaired appetite regulation.
- Conditions
- Obesity & Overweight, Metabolic Disorders, Electrotherapy
- Trial name
- DEMO-OB (NCT07562724)
- Testing
- Energy-Restricted Diet, Whole-Body Electromyostimulation (WB-EMS)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Firat University
Type 2 Diabetes, Appetite Regulation
GLycaemic Outcomes With Whey Protein in ageING
The goal of this placebo-controlled, partial crossover design study is to identify the impact of consuming whey protein before meals on free-living glucose control in older adults living with type 2 diabetes.
- Conditions
- Type 2 Diabetes, Appetite Regulation, Whey Protein, Ageing and Geriatric Health
- Trial name
- GLOWING (NCT07285811)
- Testing
- Glycaemic control with whey protein, Glycaemic control with different doses of whey protein
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Obesity & Overweight
Fuzzle System for Appetite Control and Weight Management
This study is evaluating whether the Fuzzle intraoral device can help adults with obesity lose weight when used alongside standard lifestyle counseling.
- Trial name
- NCT07527559
- Testing
- Fuzzle Intraoral Device, Lifestyle Management
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Fuzzle Operating Co.
Healthy Participants, Healthy Adult Subject
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Chronic Study
The goal of this clinical trial is to learn how eating different snack foods affects long term hunger and gut health in healthy adults. The study will be conducted remotely over 7 weeks.
- Conditions
- Healthy Participants, Healthy Adult Subject, Healthy Subjects, Healthy Adult Volunteer
- Trial name
- SMARTEATS-RCT (NCT07782593)
- Testing
- High-fibre plant-based snack bar, Control snack bars
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Circadian Misalignment, Sex Differences
Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?
This study will test whether biological sex influences how the body responds to circadian misalignment-a mismatch between the internal body clock and the timing of sleep and eating (as can occur with shift work or jet lag).
- Trial name
- NCT07441265
- Testing
- Day shift, Night shift
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Polycystic Ovarian Syndrome (PCOS)
Time Restricted Feeding Model in Women With Polycystic Ovary Syndrome
This study aims to evaluate the effects of a 16:8 time-restricted feeding (TRF) model on anthropometric, metabolic, and hormonal parameters in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT06807775
- Testing
- Dietary Intervention (time-restricted feeding model (16:8)), Dietary Intervention (energy restricted dietary intervention)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Appetite Regulation
APPETE INTAKE: A Study on the Effects of Adding an Appetite Engine to a Nutritional Drink
The aim of this study is to investigate the effect of adding an appetite engine to a high-protein oral nutritional supplement (ONS) on acute dietary intake in older adults.
- Trial name
- APPETE INTAKE (NCT07857590)
- Testing
- Test nutritional drink, Control nutritional drink
- Where
- Poland
- Volunteers
- 68 people
- Sponsor
- Nutricia Research