Clinical trials: Appetite Loss
Appetite Suppression, Weight Loss
Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
This 18 week, randomized, double blind, placebo controlled trial will examine the effects of thick dietary fibre (PGX) supplementation of a low calorie diet (LCD) on appetite, weight loss, body composition, and compliance in…
- Trial name
- NCT01109199
- Testing
- PolyGlycopleX (PGX), Rice flour
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Anorexia Nervosa, Adipokines
Adipokines and Ghrelin Concentrations in Different Stages of Anorexia Nervosa
The aim of this study is to determine serum concentrations of adiponectin (ApN), leptin and ghrelin in different stages of anorectic patients and to evaluate their relationships between biochemical, hormonal and anthropometric…
- Trial name
- NCT00602264
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Protein-Energy Malnutrition, Anorexia
Energy Dense Formula to People Living in Old Peoples Home
Dietary intake in frail elderly is often lower than estimated needs due to the combined effects of the anorexia of ageing, frailty and the presence of acute and chronic disease.
- Conditions
- Protein-Energy Malnutrition, Anorexia, Weight Change
- Trial name
- NCT01259999
- Testing
- Calogen extra strawberry
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska University Hospital
Anorexia Nervosa
rTMS for Aneroxia Nervosa in Youth
This study will examine the feasibility of off-label multilocus repetitive transcranial magnetic stimulation (rTMS) for symptoms of Anorexia Nervosa in participants between the ages of 14-24.
- Trial name
- MULTI-REX (NCT04846517)
- Testing
- Transcranial Magnetic Treatment
- Volunteers
- 45 people
- Sponsor
- University of California, Los Angeles
Eating Disorder, Anorexia Nervosa
Imaginal Exposure II Study: In-Vivo
The purpose of this study is to test if imaginal exposure therapy can decrease symptoms of eating disorders and anxiety.
- Conditions
- Eating Disorder, Anorexia Nervosa, Bulimia Nervosa, Exposure
- Trial name
- In-vivo IE II (NCT03934697)
- Testing
- imaginal exposure therapy
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Louisville
Anorexia Nervosa
Microbiome-mediated Weight, Anxiety, and Stress Dysregulation in Anorexia Nervosa
The purpose of this research study is to analyze the microorganisms residing in the gut of patients with anorexia nervosa. Research has begun to link changes in the intestinal microbiota with diseases such as inflammatory bowel…
- Trial name
- Microbiome (NCT03119272)
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anorexia, Cachexia
Olanzapine for Cancer Related Anorexia-cachexia Syndrome
Cancer anorexia-cachexia syndrome is one of the common conditions in cancer patients. Olanzapine has been demonstrated to reduce chemotherapy-induced anorexia.
- Trial name
- NCT06517199
- Testing
- Olanzapine 2.5 MG, Olanzapine 5 MG
- Where
- 2 sites in Thailand
- Volunteers
- 138 people
- Sponsor
- Mahidol University
Appetite
Survey of Prevalence of Loss of Appetite in Subject With Health Disorders
The study is an epidemiological survey to find out the incidence of loss of appetite in Indian patients suffering from various health disorders.
- Trial name
- SPLASH (NCT01592149)
- Testing
- No Drug
- Where
- India
- Volunteers
- 16,629 people
- Sponsor
- Bayer
Advanced Pancreatic Ductal Adenocarcinoma, Cancer Anorexia-Cachexia Syndrome
Nano-Megestrol Acetate for Cancer Cachexia in Advanced Pancreatic Cancer
Cancer anorexia-cachexia syndrome is a common and severe complication in patients with advanced cancer, with a particularly high prevalence in pancreatic cancer.
- Trial name
- NCT07408505
- Testing
- Nano-crystalline megestrol acetate, First-line Chemotherapy
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shandong Cancer Hospital and Institute
Body Dysmorphic Disorders, Anorexia
Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study
The place of opioid system in anorexia nervosa (AN) physiopathology is still unclear. Conflicting results were published on cerebral spinal fluid or peripheral levels in anorexia nervosa.
- Trial name
- NCT02524301
- Testing
- Positron Emission Tomography using [11C]diprenorphine
- Where
- 3 sites in France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cancer, Cachexia
Neurobehavioural and Cognitive Changes in Cancer Cachexia (CANCOG)
The goal of this observational study is to to look for changes within the brain, and changes in body-to-brain signals in people with cancer and people who do not have cancer. The main questions it aims to answer are: 1.
- Conditions
- Cancer, Cachexia, Cachexia-Anorexia Syndrome, Appetite Loss
- Trial name
- CANCOG (NCT06112964)
- Testing
- MRI/ Functional MRI, Self-reported questionnaires, Computer based tasks
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Cachexia-Anorexia Syndrome
Feasibility Study for Repurposing RET Inhibitors
The purpose of this study is to assess the effects of selpercatinib on cachexia and anorexia in patients diagnosed with NSCLC, colorectal cancer, or pancreatic cancer.
- Trial name
- FEATHER (NCT07146893)
- Testing
- Selpercatinib, Strength Assessment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Oklahoma
Anorexia Nervosa
Transcranial Magnetic Stimulation (TMS) in the Treatment of Anorexia Nervosa
Anorexia nervosa is a severe psychiatric disorder associated with food avoidance and body image distortion, that is feeling fat despite being underweight.
- Trial name
- NCT05368844
- Testing
- rTMS treatment using BrainsWay Model 104 system with H1-Coil
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Diego
Anorexia Nervosa, Bulimia Nervosa
Neurobiology of Eating Disorders Treatments
Background. Treatments of eating disorders result too often in partial psychological and physical remission, chronic course, dropout, relapse and death, with no fully known explanations for this failure.
- Trial name
- NEDT (NCT01990755)
- Testing
- CBT (Cognitive Behavioral Therapy), IBPP (individual psychology brief psychotherapy), CBT + OLANZAPINE
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- University of Turin, Italy
Weight Loss
ELIRA 2: Safety and Effectiveness of TENS Assisted Weight Loss and Appetite Suppression
The objectives of this study are to demonstrate safety and effectiveness of a wearable patch TENS system (Appendix 2) in driving weight loss and appetite suppression when coupled with an integrated weight loss reduction strategy.
- Trial name
- ELIRA_2 (NCT03936699)
- Testing
- Transcutaneous Nerve Stimulator (TENS), Diet & Exercise
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Elira Therapeutics, Inc.
Anorexia Nervosa, Metabolic Syndrome
Does Metabolic Syndrome Exist in Anorexia Nervosa?
The purpose of this study is to examine whether body fat distribution changes that occur with weight gain in women recovering from anorexia nervosa are transient or persistent, and if they are associated with other features of…
- Trial name
- NCT00271921
- Testing
- Calorie controlled diet
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Anorexia
Body Image Disorder in Anorexia Nervosa and Virtual Reality
Evaluation of the tolerance and acceptability of the virtual representation of its body image.
- Trial name
- REVAM (NCT03118921)
- Testing
- Virtual reality
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Brest
Bulimia Nervosa, Anorexia Nervosa
Repetitive Transcranial Magnetic Stimulation of the DMPFC for Anorexia and Bulimia: an Open-Label Case Series
This project proposes to perform a pilot study of fMRI targeted Dorsomedial Prefrontal Cortex repetitive transcranial magnetic stimulation (DMPFC-rTMS) on individuals diagnosed with Bulimia Nervosa (BN) and Anorexia Nervosa (AN).
- Trial name
- NCT04409704
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Periodontal Diseases, Eating Disorder
Periodontal Impact of Eating Disorders (the PERIOED Study)
This study evaluated the periodontal status of patients suffering from eating disorders (anorexia nervosa and bulimia nervosa). The work hypothesis is that eating disorder patients have a higher risk for periodontal diseases than…
- Conditions
- Periodontal Diseases, Eating Disorder, Anorexia Nervosa, Bulimia Nervosa
- Trial name
- PERIOED (NCT02960152)
- Testing
- diagnostic
- Where
- 2 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Paris 7 - Denis Diderot
Non Small Cell Lung Cancer
Circulating and Molecular Markers Involved in the Processes of Cachexia, Anorexia and Sarcopenia in Patients With NSCLC
The study aim to evaluate whether some substances produced by muscle or adipose tissue may play a role in the course of the disease by interfering with the effectiveness of therapies.
- Trial name
- SARCLUNG (NCT06808113)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna