Clinical trials: Appetite Loss
Anorexia, Generalized Anxiety
Overgeneralization of Conditioned Fear as a Pathogenic Marker of Anorexia Nervosa
Anorexia nervosa is a chronic mental health condition characterized by maladaptive food consumption (i.e., hypophagia) and distorted body image.
- Trial name
- NCT02148042
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity, Osteoporosis
Milk Supplementation and Energy Balance.
The aim of the project is to determine if milk supplementation during a caloric restriction program facilitates the lost of weight, improves the appetite control and attenuates the decrease of bone mineral content in low-calcium…
- Trial name
- NCT00729170
- Testing
- Supplementation of milk (35% more calcium)
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Laval University
Bulimia Nervosa, Anorexia Nervosa
Avoidance-driven Decision Making and Learning in Anorexia Nervosa and Bulimia Nervosa
The purpose of this study is to investigate areas of the brain responsible for avoidance learning in adults with eating disorders using brain imaging techniques, computer tasks, and self-report questionnaires and interviews.
- Trial name
- NCT06566612
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa
Active Lifestyle Intervention in Anorexia Nervosa: a Comprehensive Study
The goal of this study is to perform a comprehensive analysis of varied health markers and analyze the impact of lifestyle interventions on the prognosis of anorexia nervosa (AN) patients.
- Trial name
- DiANa (NCT06866301)
- Testing
- Progressive Resistance Exercise
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Anorexia Nervosa
Microbiome Shifts in Adolescent Anorexia Nervosa
The aim of this study is to evaluate the effect of starvation and recovery in adolescent anorexia nervosa patients in regard to microbiome activity and composition and to elucidate potential connections between weight gain…
- Trial name
- MaAN (NCT02962726)
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Obesity
Effects of Grapefruit or Grapefruit Juice on Anthropometry, Dietary Intakes, Appetite, and Metabolic Profile in Overweight and Obese Young and Middle-Aged Adults
This trial examines the effects of grapefruit or grapefruit juice on anthropometry, dietary intakes, appetite, and metabolic profile in overweight and obese young and middle-aged adults.
- Trial name
- GJW (NCT00581074)
- Testing
- diet (grapefruit or grapefruit juice)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Appetite Suppression, Weight Loss
Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
This 18 week, randomized, double blind, placebo controlled trial will examine the effects of thick dietary fibre (PGX) supplementation of a low calorie diet (LCD) on appetite, weight loss, body composition, and compliance in…
- Trial name
- NCT01109199
- Testing
- PolyGlycopleX (PGX), Rice flour
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Anorexia Nervosa
A Randomised Controlled Trial on the Networks Integrating Anxiety and Metabolism in Anorexia Nervosa
Anorexia nervosa (AN) is known as the psychiatric disorder with the highest mortality rate as long-term calorie restriction causes medical complications and suicide risk.
- Trial name
- NAMA (NCT06814002)
- Testing
- Meal with 400 kilocalories, Meal without calories
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umeå University
Obesity
The Energy Balance Study
Very low carbohydrate diets and high-complex carbohydrate, low-fat diets are popular weight-loss methods in the United States. The purpose of the Energy Balance Study is to explore how extreme differences in diet affect eating…
- Trial name
- EBS (NCT01029483)
- Testing
- Low carbohydrate diet, High-carbohydrate ad libitum intervention, High carbohydrate diet-energy matched intervention
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Anorexia Nervosa, Bulimia Nervosa
Neurobiology of Anorexia and Bulimia Nervosa
The purpose of this study is to investigate areas of the brain responsible for appetite regulation. More specifically, the investigators would like to study changes in brain activation, e.g., changes in blood flow and oxygen use…
- Trial name
- NCT04626219
- Testing
- Imaging, fast, regulated meals
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa
Effectiveness of Enhanced Cognitive Behavioral Therapy (CBT-E) in the Treatment of Anorexia Nervosa
The primary objective of this study is to gain knowledge about the effectiveness of enhanced cognitive behavioral therapy (CBT-E) for anorexia nervosa (AN).
- Trial name
- NCT02745067
- Testing
- enhanced cognitive behavioral therapy
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Obesity
Inter Individual Variation in Weight Loss Response to Exercise
The identification and characterization of individuals who vary in their response to exercise-induced weight loss is important. Weight loss in response to exercise is variable and it remains unknown who will succeed, why, and…
- Trial name
- NCT00773214
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Anorexia Nervosa, Eating Disorder
Severe Anorexia Nervosa Personal Recovery
A growing qualitative literature about personal recovery process in mental disorders emerges. However in Anorexia Nervosa (AN), it remains few understood, especially in severe AN during adolescence.
- Trial name
- ANAPR (NCT03712384)
- Testing
- Semi structured face to face interview
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Institut Mutualiste Montsouris
Anorexia
Oxytocin and Incitement to Use Olfactory Stimuli in Restrictive Anorexia Nervosa
This prospective pilot study will compare adolescents with restrictive anorexia nervosa who participated for 3 months at olfactory workshops, patients who did not, and healthy patients.The groups will be evaluated before the…
- Trial name
- NCT02333500
- Testing
- olfactory workshop, other workshop, No intervention
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondation Lenval
Obesity
Safety and Efficacy of APD356 in the Treatment of Obesity
This is a research study of an investigational drug, APD356, a novel, selective 5-HT2c receptor agonist, in clinical development as a potential treatment for obesity.
- Trial name
- NCT00104507
- Testing
- APD356
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Overweight and Obese Women
Impact of Beta-glucan Supplementation During Calorie and Carbohydrate-restricted Diet on Body Weight and Body Fat Loss, Appetite, and Gastrointestinal Appetite Hormones.
This study will investigate whether beta-glucan supplementation, when added to an energy and carbohydrate-restricted diet, facilitates body weight and body fat loss, and leads to less detrimental changes in subjective appetite…
- Trial name
- NCT07299942
- Testing
- Beta-glucan addition to a restricted calorie of meal replacements and carbohydrate diet.
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Anorexia Nervosa
PET Imaging Study of Recovered Anorexics
Several studies in the past suggest that individuals who have or had anorexia nervosa may have alterations in brain serotonin. Serotonin seems to play an important role in regulating anxiety, mood, and other symptoms found in…
- Trial name
- NCT00603018
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Anorexia Nervosa
Anorexia Nervosa Genetics Initiative
The Anorexia Nervosa Genetics Initiative (ANGI) is the largest and most rigorous genetic investigation of eating disorders ever conducted.
- Trial name
- ANGI (NCT01916538)
- Where
- United States
- Volunteers
- 22,445 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill