Clinical trials: Aphthous Ulcer
Recurrent Aphthous Stomatitis
Influence of Different Doses of the Vitamin B12 on Recurrent Aphthous Stomatitis
Background: The frequency of recurrent aphthous stomatitis (RAS), the most common oral mucosa lesions seen in primary care, is up to 25% in the general population.
- Trial name
- NCT01127724
- Testing
- vitamin B12 treatment
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Meir Medical Center
Recurrent Aphthous Stomatitis
Effect of Sodium Lauryl Sulfate on Recurrent Aphthous Stomatitis
Sodium lauryl sulfate (SLS) is an anionic detergent that has been used as the major or sole surfactant in most dentifrices. But it is known to local irritating factor to oral mucosa and skin and results in many side effects.
- Trial name
- NCT01501409
- Testing
- sodium lauryl sulfate
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Aphthous Ulcer
Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients
The purpose of this study is to compare the efficacy of laser photobiomodulation and "Magic Mouthwash" for treatment of pain in pediatric patients with aphthous ulcers , to assess how photobiomodulation influences the rate of…
- Trial name
- NCT06819033
- Testing
- PBM Therapy, Maalox plus Benadryl
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Canker Sore
Luminance RED for Canker Sores
Canker sores, also called aphthous ulcers, are small, shallow lesions that develop on the soft tissues in your mouth or at the base of your gums.
- Trial name
- NCT04914533
- Testing
- Luminance RED Low Level Laser Therapy Device
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ProofPilot
Aphthous Stomatitis
Systemic Zinc Sulphate in Treatment of Recurrent Aphthous Ulcerations:A Doubleblind, Placebo Controled Study
Recurrent aphthous stomatitis (RAS) is one of the most common of oral mucosa diseases that affects approximately 20% of the general population.
- Trial name
- NCT01210014
- Testing
- zinc sulphate 220mg/day in one dosage
- Where
- Iran
- Volunteers
- 14 people
- Sponsor
- Qazvin University Of Medical Sciences
Aphthous Stomatitis (Major) (Minor), Treatment Compliance
Efficacy of Thyme Honey in The Management of Oral Aphthous Ulcers
Recurrent aphthous stomatitis (RAS) is considered the most common oral mucosal lesion, present first in childhood or adolescence.
- Trial name
- NCT06421038
- Testing
- Thyme honey, Kenalog
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- British University In Egypt
Stomatitis, Aphthous Ulcer
Non-Thermal Plasma vs. Low-Level Laser Therapy for Recurrent Oral Ulcers
The goal of this clinical trial (pilot study) is to evaluate the feasibility and preliminary effectiveness of Non-Thermal Plasma (NTP) in treating pain and accelerating healing in 50 patients with Recurrent Oral Ulcers (ROUs).
- Trial name
- NCT07322666
- Testing
- Non-Thermal Plasma (NTP), Low-Level Laser Therapy (LLLT)
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Recurrent Aphtous Stomatitis
Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis
The objective of the study is to assess the superiority of apremilast in comparison with placebo to achieve Complete Remission (CR) of oral ulcers at Week 12, in patients with severe Recurrent aphtous stomatitis resistant or…
- Trial name
- PREMS (NCT04227314)
- Testing
- Apremilast
- Where
- 21 sites in France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Rouen
Oral Ulcer, Oral Mucositis
A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers
The goal of this clinical trial is to learn if a new 1% Phenytoin mucoadhesive film is safe and works to treat oral ulcers in healthy adult volunteers and patients with oral ulcers.
- Conditions
- Oral Ulcer, Oral Mucositis, Aphthous Stomatitis
- Trial name
- PHENO-FILM (NCT07890428)
- Testing
- 1% Phenytoin Mucoadhesive Film, Blank Mucoadhesive Film
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Recurrent Aphthous Stomatitis, Mouth Ulcer
The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral Mucosa
This is a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the efficacy and safety of spirulina supplementation in patients with radiation-induced oral mucositis (RIOM) receiving…
- Trial name
- NCT07723612
- Testing
- Spirulina Tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Photobiomodulation, Stomatitis, Aphthous
Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous Stomatitis
Photobiomodulation (PBM) is a therapy that stimulates repair, pain relief, and reduces inflammation. The aim of this study is to evaluate the effectiveness of a new PBM protocol in the treatment and pain relief of RAS lesions.
- Trial name
- NCT06416046
- Testing
- Gemini laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Cutaneous Manifestations, Skin Manifestations
Cutaneous Manifestations of Coronavirus Disease 2019(COVID-19).
An outbreak of Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-coV-2) occurred in Wuhan city, Hubei province, China in December 2019.
- Conditions
- Cutaneous Manifestations, Skin Manifestations, COVID-19, COVID-19 Pneumonia
- Trial name
- NCT05094687
- Where
- Pakistan
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Recurrent Aphthous Stomatitis
α-Mangostin Hydrogel Film With Chitosan Alginate Base for Recurrent Aphthous Stomatitis (RAS)
Recurrent Aphthous Stomatitis (RAS) is experienced by almost everyone and appears suddenly. Even though the risk of death due to the condition is small, its presence can make a person feel uncomfortable eating, drinking, and…
- Trial name
- AM-RAS (NCT06039774)
- Testing
- α-Mangostin Hydrogel Film With Chitosan Alginate Base
- Where
- Indonesia
- Volunteers
- 48 people
- Sponsor
- Universitas Padjadjaran
Oral Ulcer, Aphthous Recurrent Ulcers
Treatment of Aphtous Ulcers With Photodynamic Therapy
The search for methods that can shorten the treatment process of aphthous ulcers, the etiology of which is not fully understood, continues.
- Trial name
- NCT06379438
- Testing
- Photodynamic therapy (indocyanine green+laser)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Periodic Fever, Aphthous Stomatitis
Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)
The purpose of study is to see if adding probiotics to corticosteroid treatment for children with PFAPA could improve the health and daily of patients through reduction in febrile period frequency and length, along with…
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis
- Trial name
- PFAPA (NCT02535962)
- Testing
- Lactobacillus acidophilus and Bifidobacterium lactis
- Sponsor
- Connecticut Children's Medical Center
Recurrent Mouth Ulcers
Omega-3 and Quality of Life in Recurrent Aphthous Stomatitis Patients
The study aims at evaluating the effect of omega-3 on patients suffering recurrent oral aphthous ulcers
- Trial name
- NCT01831453
- Testing
- omega-3
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- October 6 University
Recurrent Aphthous Stomatitis
Effect of Zinc Oxide Ointment on Recurrent Aphthous Stomatitis
This randomized placebo-controlled trial evaluated the effectiveness of zinc oxide ointment in the treatment of recurrent aphthous stomatitis (RAS).
- Trial name
- ZO-RAS (NCT07565181)
- Testing
- zinc oxide, Placabo
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Faculty of Dental Medicine for Girls
Aphthous Ulcer
The Efficacy of Nigella Sativa Oil Mouth Rinse in the Management of Recurrent Minor Aphthous Ulcer
This research aims to investigate the effectiveness of Nigella Sativa Oil Mouth Rinse application both clinically and biochemically as a suitable affordable treatment modality for Management of Recurrent Minor Aphthous Ulcer
- Trial name
- NCT06013202
- Testing
- Nigella Sativa Oil Mouth Rinse, isotonic (normal saline) with concentration 0.90% of sodium chloride (NaCl)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nada Sherif
Oral Ulcer
Basil Extract (Ocimum Basilicum) in the Management of Recurrent Aphthous Stomatitis
A randomized double-blind placebo controlled trial will be carried out on 20 patients complaining from aphthus ulcer and 10 patient healthy control 10 patients treated with mucoadhesive gel containing 2% of basil extract 4 times…
- Trial name
- RCT (NCT04710888)
- Testing
- use of basil extract gel in treatment of aphthus ulcer, no treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tanta University