Clinical trials: Aphthous Ulcer
Stomatitis, Aphthous Ulcer
Non-Thermal Plasma vs. Low-Level Laser Therapy for Recurrent Oral Ulcers
The goal of this clinical trial (pilot study) is to evaluate the feasibility and preliminary effectiveness of Non-Thermal Plasma (NTP) in treating pain and accelerating healing in 50 patients with Recurrent Oral Ulcers (ROUs).
- Trial name
- NCT07322666
- Testing
- Non-Thermal Plasma (NTP), Low-Level Laser Therapy (LLLT)
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Aphthous Stomatitis
Therapeutic Effects of "Ibuprofen, Diphenhydramine and Aluminium MgS" on Recurrent Aphthous Stomatitis
The intention of the study is to study the effects of Ibuprofen, Diphenhydramine and Aluminium MgS in decreasing the signs of recurrent aphthous stomatitis (RAS)
- Trial name
- NCT01293968
- Testing
- Ibuprofen, Diphenhydramine and Aluminium MgS, Diphenhydramine and Aluminium MgS
- Where
- 2 sites in Iran
- Volunteers
- 37 people
- Sponsor
- Qazvin University Of Medical Sciences
Recurrent Mouth Ulcers
Omega-3 and Quality of Life in Recurrent Aphthous Stomatitis Patients
The study aims at evaluating the effect of omega-3 on patients suffering recurrent oral aphthous ulcers
- Trial name
- NCT01831453
- Testing
- omega-3
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- October 6 University
Recurrent Aphthous Stomatitis
Clinical Evaluation of Fluid Extract of Chamomilla Tincture for Oral Aphthae
Recurrent aphthous stomatitis is a difficult to treat and quite common chronic inflammatory disease of the oral mucosa. This study evaluates the fluid extract from Chamomilla recutita's safety and effectiveness in treatment of…
- Trial name
- NCT01122147
- Testing
- chamomilla tincture mouthwash
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Mashhad University of Medical Sciences
Aphthous Stomatitis, Recurrent, Aphthous Stomatitis
Effect of Alum Stone Containing Mucosal Adhesive Patches on Healing of Recurrent Aphthous Stomatitis
The evaluation of recurrent aphthous stomatitis (RAS) was performed by an oral medicine specialist, who relied on the clinical manifestations of the condition.
- Conditions
- Aphthous Stomatitis, Recurrent, Aphthous Stomatitis, Aphthous Ulcer
- Trial name
- NCT06960278
- Testing
- Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5., Control, ALUMSTONE
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Of Anbar
Aphthous Stomatitis
Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous Ulcers
The purpose of this study is to evaluate the effectiveness of mucoadhesive film with or without Acmella oleracea extract compared to standard treatment by using 0.1% triamcinolone acetonide in pain relief, promoting wound…
- Trial name
- NCT06622213
- Testing
- mucoadhesive film with Acmella oleracea extract, Triamcinolone Acetonide 0.1% Oromucosal Paste, mucoadhesive film without Acmella oleracea extract
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Recurrent Aphthous Stomatitis
A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous Stomatitis
This is a randomized, double blind, placebo controlled trial of the use of pentoxifylline (oxpentifylline) for the treatment of recurrent mouth ulcers.
- Trial name
- NCT00315679
- Testing
- Pentoxifylline (also known as oxpentifylline)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases
This study evaluates the effectiveness of topical NAVS naphthalan in the treatment of oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS).
- Trial name
- NCT02920658
- Testing
- NAVS Naphthalan, 0.05% Betamethasone dipropionate
- Where
- Croatia
- Volunteers
- 57 people
- Sponsor
- Ivan Alajbeg
Recurrent Aphthous Stomatitis
Efficacy and Safety Study of Yunnan Baiyao on Minor Recurrent Aphthous Stomatitis
Recurrent aphthous stomatitis (RAS) is a common recurrent oral disorder with no curative treatment available to date. The challenge remains in patients that do develop drug resistance and/or secondary infection, although topical…
- Trial name
- NCT01652625
- Testing
- Yunnan Baiyao toothpaste
- Volunteers
- 227 people
- Sponsor
- Peking University
Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood.
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea, Tonsillitis, Tonsil Disorder
- Trial name
- NCT05656365
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Recurrent Aphthous Stomatitis
Effect of Sodium Lauryl Sulfate on Recurrent Aphthous Stomatitis
Sodium lauryl sulfate (SLS) is an anionic detergent that has been used as the major or sole surfactant in most dentifrices. But it is known to local irritating factor to oral mucosa and skin and results in many side effects.
- Trial name
- NCT01501409
- Testing
- sodium lauryl sulfate
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Aphthous Stomatitis, Burning Mouth Syndrome
Evaluation and Treatment of Oral Soft Tissue Diseases
This study offers evaluation and treatment of patients with diseases of the mouth or systemic diseases that involve the mouth. The protocol is not designed to test new treatments; rather, patients will receive current standard of…
- Conditions
- Aphthous Stomatitis, Burning Mouth Syndrome, Lichen Planus, Mouth Disease
- Trial name
- NCT00001601
- Testing
- Electrocardiogram, Biopsies, Diagnostic imaging
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Treatment of Minor Aphthous Ulcers
Evaluation of Topical Probiotic Gel Versus Triamcinolone in Minor Recurrent Aphthous Ulcers
This study looks at a new way to treat minor recurrent aphthous ulcers. These ulcers are painful, round or oval sores that show up on the soft, non-chewing surfaces of the mouth (like the inside of the cheeks or lips).
- Trial name
- NCT07672730
- Testing
- Probiotic gel, Triamcinelone acetonide
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Aphthous Ulcer Recurrent
Corchorus Olitorius Buccal Films for the Treatment of Recurrent Minor Aphthous Ulcerations
A methanol extract of Corchorus olitorius edible plant was perpared for extration of glycosideal compounds. the extract was tested for its efficacy as antiinflammatory and analgesic activity invitro and approved by the…
- Trial name
- NCT05392842
- Testing
- Corchorus Olitorius Buccal fast dissolving Films, plain mucoadhesive fast dissolving film
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Deraya University
Recurrent Aphtous Stomatitis
Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis
The objective of the study is to assess the superiority of apremilast in comparison with placebo to achieve Complete Remission (CR) of oral ulcers at Week 12, in patients with severe Recurrent aphtous stomatitis resistant or…
- Trial name
- PREMS (NCT04227314)
- Testing
- Apremilast
- Where
- 21 sites in France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Rouen
Recurrent Aphthous Stomatitis
Apremilast for RAS
Determination of treatment efficacy and safety of Apremilast in patients with RAS
- Trial name
- NCT03690544
- Testing
- Apremilast 30mg
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Aphthous Stomatitis
Efficacy and Safety of BALI Association in the Treatment of Aphthous Ulcerations
The purpose of this study is to evaluate the efficacy and safety of BALI association in the treatment of aphthous ulceration.
- Trial name
- NCT05542173
- Testing
- BALI association
- Where
- Brazil
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- EMS
Behcet's Syndrome
Colchicine Randomized Double-Blind Controlled Crossover Study in Behcet's Disease
Colchicine was first used in Behcet's Disease (BD), in 1977. There are controversial reports of the efficacy of Colchicine in BD.
- Trial name
- NCT00700297
- Testing
- Colchicine
- Where
- Iran
- Volunteers
- 169 people
- Sponsor
- Tehran University of Medical Sciences
Drug Effect, Drug Effect Prolonged
Niosomal Propolis as Oromucoadhesive Film: In-vitro, Ex-vivo & In-vivo Investigations
A total of 24 patients suffering from RAU, they were divided into two groups each included 12 patients. The first group was treated by the propolis mucoadhesive film and the second group received the film without the active…
- Trial name
- NCT03615820
- Testing
- Niosomal PPE oromucoadhesive film, Oromucoadhesive film
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- British University In Egypt
Aphthous Stomatitis
Hyaluronic Acid in Counteracting Aphthous Stomatitis
Oral mucosal ulcers can determine a real worsening of the quality of life. Conventional therapy usually lasts not less than 2-3 weeks, and carries a high risk of serious side effects; furthermore, ulcers often recur.
- Trial name
- NCT04884464
- Testing
- Hyaluronic acid-based gel, Chlorhexidine Gluconate
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Urbino "Carlo Bo"