Clinical trials: Aphthous Stomatitis
Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis
Curcumin and Nanocurcumin in Oral Aphthous Ulcer
Recurrent aphthous ulcer is a painful inflammatory lesion with a high prevalence. Since the etiology is not clear, several strategies have been proposed to reduce pain and severity of its symptoms.
- Trial name
- NCT04385979
- Testing
- Gel
- Where
- Iran
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Recurrent Aphthous Stomatitis
Topical Hyaluronic Acid and Recurrent Aphthous Stomatitis.
This study was conducted to estimate the hypothesis that the topical hyaluronic acid mouthwash have no role in the treatment of recurrent aphthous stomatitis
- Trial name
- NCT04265001
- Testing
- Hyaluronic acid in the form of hyaluronan sodium 25 mg/100 ml as a mouthwash
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Aphthous Stomatitis
Tokushima Night Guard for Recurrent Aphthous Stomatitis
The investigators will investigate whether the night guard can suppress the development of recurrent aphthous stomatitis (RAS). The investigators will record the patients' oral condition for 60 days before and after intervention…
- Trial name
- NCT02890524
- Testing
- night guard
- Where
- 2 sites in Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Tokushima
Drug Effect, Drug Effect Prolonged
Niosomal Propolis as Oromucoadhesive Film: In-vitro, Ex-vivo & In-vivo Investigations
A total of 24 patients suffering from RAU, they were divided into two groups each included 12 patients. The first group was treated by the propolis mucoadhesive film and the second group received the film without the active…
- Trial name
- NCT03615820
- Testing
- Niosomal PPE oromucoadhesive film, Oromucoadhesive film
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- British University In Egypt
Recurrent Aphthous Stomatitis
A Trial of Pentoxifylline for the Treatment of Recurrent Aphthous Stomatitis
This is a randomized, double blind, placebo controlled trial of the use of pentoxifylline (oxpentifylline) for the treatment of recurrent mouth ulcers.
- Trial name
- NCT00315679
- Testing
- Pentoxifylline (also known as oxpentifylline)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Manchester University NHS Foundation Trust
Intense-exuberant Stomach Fire Syndrom, Acute Pericoronitis
Effectiveness and Clinical Mechanism of Huanglian-Jiedu Decoction in Patients With Intense-exuberant Stomach Fire Syndrome
This clinical research focus on evaluating the effectiveness of Huanglian-Jiedu Decoction in patients with intense-exuberant stomach fire syndrome (one of the common TCM syndrome)of acute pericoronitis,minor recurrent aphthous…
- Conditions
- Intense-exuberant Stomach Fire Syndrom, Acute Pericoronitis, Recurrent Aphthous Stomatitis, Recurrent Herpes Simplex Labialis
- Trial name
- NCT03469232
- Testing
- Huanglian-Jiedu Decoction
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- China Academy of Chinese Medical Sciences
Periodic Fever, Aphthous Stomatitis
Probiotics and Corticosteroids for Treating Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis (PFAPA)
The purpose of study is to see if adding probiotics to corticosteroid treatment for children with PFAPA could improve the health and daily of patients through reduction in febrile period frequency and length, along with…
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, Cervical Adenitis
- Trial name
- PFAPA (NCT02535962)
- Testing
- Lactobacillus acidophilus and Bifidobacterium lactis
- Sponsor
- Connecticut Children's Medical Center
Autoimmune Connective Tissue Disorder, Immune System Diseases
Anakinra for Behcet s Disease
Background: Behcet's disease (BD) is an autoimmune disease where the immune system attacks the body. People with BD may develop oral or genital ulcers, skin problems, and eye disease.
- Trial name
- NCT01441076
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Stomatitis, Aphthous
Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation
The aim this study was to investigate the efficacy of Er,Cr:YSGG laser irradiation in reducing pain and on healing rate of recurrent aphthous stomatitis 40 patients with RAS were included to the study.
- Trial name
- NCT02925182
- Testing
- Er,Cr:YSGG Laser
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Oral Lichen Planus, Recurrent Aphthous Stomatitis
Topical "Non-Aromatic Very Rich in Steranes" (NAVS) Naphthalan for the Treatment of Oral Mucosal Diseases
This study evaluates the effectiveness of topical NAVS naphthalan in the treatment of oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS).
- Trial name
- NCT02920658
- Testing
- NAVS Naphthalan, 0.05% Betamethasone dipropionate
- Where
- Croatia
- Volunteers
- 57 people
- Sponsor
- Ivan Alajbeg
Canker Sore
Salivary Catecholamines in Aphthous Stomatitis (Canker Sores)
The purpose of this study is to examine how compounds produced in patients with canker sores affect wound healing.
- Trial name
- NCT00556686
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Recurrent Aphthous Stomatitis
Influence of Different Doses of the Vitamin B12 on Recurrent Aphthous Stomatitis
Background: The frequency of recurrent aphthous stomatitis (RAS), the most common oral mucosa lesions seen in primary care, is up to 25% in the general population.
- Trial name
- NCT01127724
- Testing
- vitamin B12 treatment
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Meir Medical Center
Minor Recurrent Aphthous Stomatitis Lesions
The Effect of 2-DeNT Oral Topical Powder on Minor Recurrent Aphthous Ulcer
This is a prospective, randomized, blinded, placebo-controlled, crossover clinical trial to evaluate the efficacy of 2-DeNT oral topical powder in the treatment of recurrent aphthous stomatitis (RAS).
- Trial name
- NCT02142543
- Testing
- 2-DeNT powder
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Recurrent Mouth Ulcers
Omega-3 and Quality of Life in Recurrent Aphthous Stomatitis Patients
The study aims at evaluating the effect of omega-3 on patients suffering recurrent oral aphthous ulcers
- Trial name
- NCT01831453
- Testing
- omega-3
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- October 6 University
Recurrent Aphthous Stomatitis
Efficacy and Safety Study of Yunnan Baiyao on Minor Recurrent Aphthous Stomatitis
Recurrent aphthous stomatitis (RAS) is a common recurrent oral disorder with no curative treatment available to date. The challenge remains in patients that do develop drug resistance and/or secondary infection, although topical…
- Trial name
- NCT01652625
- Testing
- Yunnan Baiyao toothpaste
- Volunteers
- 227 people
- Sponsor
- Peking University
Aphthous Stomatitis
Therapeutic Effects of "Ibuprofen, Diphenhydramine and Aluminium MgS" on Recurrent Aphthous Stomatitis
The intention of the study is to study the effects of Ibuprofen, Diphenhydramine and Aluminium MgS in decreasing the signs of recurrent aphthous stomatitis (RAS)
- Trial name
- NCT01293968
- Testing
- Ibuprofen, Diphenhydramine and Aluminium MgS, Diphenhydramine and Aluminium MgS
- Where
- 2 sites in Iran
- Volunteers
- 37 people
- Sponsor
- Qazvin University Of Medical Sciences
Recurrent Aphthous Stomatitis
Effect of Sodium Lauryl Sulfate on Recurrent Aphthous Stomatitis
Sodium lauryl sulfate (SLS) is an anionic detergent that has been used as the major or sole surfactant in most dentifrices. But it is known to local irritating factor to oral mucosa and skin and results in many side effects.
- Trial name
- NCT01501409
- Testing
- sodium lauryl sulfate
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Recurrent Aphthous Stomatitis
Clinical Evaluation of Fluid Extract of Chamomilla Tincture for Oral Aphthae
Recurrent aphthous stomatitis is a difficult to treat and quite common chronic inflammatory disease of the oral mucosa. This study evaluates the fluid extract from Chamomilla recutita's safety and effectiveness in treatment of…
- Trial name
- NCT01122147
- Testing
- chamomilla tincture mouthwash
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Mashhad University of Medical Sciences
Aphthous Stomatitis
Systemic Zinc Sulphate in Treatment of Recurrent Aphthous Ulcerations:A Doubleblind, Placebo Controled Study
Recurrent aphthous stomatitis (RAS) is one of the most common of oral mucosa diseases that affects approximately 20% of the general population.
- Trial name
- NCT01210014
- Testing
- zinc sulphate 220mg/day in one dosage
- Where
- Iran
- Volunteers
- 14 people
- Sponsor
- Qazvin University Of Medical Sciences
Recurrent Aphthous Stomatitis
Oral Vitamin B12 as Potential Treatment of Recurrent Aphthous Stomatitis
Background: Recurrent aphthous stomatitis is a common phenomenon in Primary Medicine.Frequency of the phenomenon can be as high as 25% of the general population and the recurrence of the problem can be up to 50%.Different…
- Trial name
- NCT00288769
- Where
- Israel
- Sponsor
- Soroka University Medical Center