Clinical trials: Aphakia
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of Monofocal Toric Intraocular Lens (IOL)
This study is a prospective, multicenter, randomized, double masked trial comparing an investigational Monofocal Toric intraocular lens (IOL) (PODEYE TORIC CYL 1.5 D) and a commercially available non-toric monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT06399211
- Testing
- PODEYE TORIC Monofocal IOL, Alcon AcrySof SA60AT Monofocal IOL
- Volunteers
- 261 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract Senile
Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)
Extended depth of focus (EDF) intraocular lens (IOL) versus Monofocal intraocular lens (IOL)
- Trial name
- NCT07092020
- Testing
- EDF, Monofocal IOL
- Where
- 14 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 220 people
- Sponsor
- Carl Zeiss Meditec AG
Aphakia, Presbyopia
Evaluation of AcrySof IQ Vivity Extended Vision Intraocular Lenses
The purpose of this post-market study is to describe the long-term safety and performance of AcrySof IQ Vivity and AcrySof IQ Vivity Toric intraocular lens (IOL) models in a real-world setting through routine clinical practice.
- Conditions
- Aphakia, Presbyopia, Residual Refractive Cylinder
- Trial name
- NCT06541795
- Testing
- AcrySof IQ Vivity Extended Vision IOL
- Where
- United States
- Sponsor
- Alcon Research
Aphakia, Postcataract, Cataract; Eye Disease
Safety and Efficacy of a Trifocal Intraocular Lens (IOL) POD L GF in Comparison With a Multifocal and a Monofocal IOL
The objectives of the Post-Market Follow-up (PMCF) clinical investigation are to determine the safety and performance of a hydrophobic trifocal intraocular lens POD L GF in comparison with two comparator lenses: another…
- Trial name
- NCT04005651
- Testing
- POD L GF IOL, Symfony® IOL, AcrySof® IOL
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Aphakia Cataract
Clinical Evaluation of the Adaptilens Accommodating IOL
The goals of this feasibility study are to learn more about the performance of the intraocular lens (IOL), if the IOL is safe for use, and what the best surgical techniques are for implanting the IOL in patients who require…
- Trial name
- NCT07607860
- Testing
- Accomodating Intra Ocular Lens, Monofocal Intra Ocular Lens
- Volunteers
- 100 people
- Sponsor
- Adaptilens, Inc.
Aphakia, Cataract
Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT03895034
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- RxSight, Inc.
Aphakia, Corneal Astigmatism
Evaluation of the Safety and Performance of the HARMONI® Toric Lens
The purpose of this study was to evaluate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic (HMTIOL) in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Aphakia, Corneal Astigmatism, Cataract
- Trial name
- NCT03050697
- Testing
- HARMONI® Modular Toric Intraocular Lens, Cataract extraction with intraocular lens (IOL) implantation
- Where
- New Zealand
- Volunteers
- 16 people
- Sponsor
- ClarVista Medical
Aphakia, Cataract
Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism
The objective of this study is to evaluate uncorrected distance vision and quality of vision as measured by the McAlinden QoV questionnaire 3 months following the final lock-in treatment of the implanted RxSight Light Adjustable…
- Trial name
- NCT03729024
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 21 people
- Sponsor
- RxSight, Inc.
Pediatric Cataract, Congenital Cataract
Toric Intraocular Lens Implantation for Pediatric Aphakia
Here, we conducted a nonrandomized clinical trial aims to evaluate and compare the prognosis of visual function in children of these two types of IOL implantation over a three-year postoperative period.
- Trial name
- NCT07088796
- Testing
- Toric IOL implantation, Non-toric IOL implantation
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Aphakia, Cataract
Single Center Exploratory Study To Evaluate The Use Of The RxSight Light Adjustable Lens (LAL) And The Light Delivery Device (LDD) To Improve Visual Outcomes
The objective of this study is to evaluate, for the visual correction of aphakia, whether the RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) can be used to improve visual outcomes after performing adjustments…
- Trial name
- NCT04529616
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- Mexico
- Volunteers
- 79 people
- Sponsor
- RxSight, Inc.
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Cataracts
Accuracy of Holladay 2 Formula in the Absence of Lens Thickness
Hypothesis: Holladay 2 formula is still accurate even used without lens thickness data.
- Trial name
- NCT01846078
- Testing
- optical biometric measurement (IOLMaster)
- Where
- Thailand
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Aphakia
Bicentric Clinical Investigation to Assess Safety and Performance of LuxBoost IOL
The study purpose is to demonstrate safety and performance of bilateral implantation of LuxBoost intraocular lenses compared with the LuxGood Monofocal lens.
- Trial name
- LuxBoost (NCT06258707)
- Testing
- LuxBoost IOL, LuxGood IOL
- Where
- 2 sites in France
- Volunteers
- 58 people
- Sponsor
- Cutting Edge SAS
Aphakia, Presbyopia
Real-World Study of Vivity Intraocular Lenses (IOLs)
The primary objective of this clinical study is to assess the clinical performance of the AcrySof IQ Vivity Extended Vision IOL in a Chinese population.
- Trial name
- NCT04800016
- Testing
- AcrySof IQ Vivity Extended Vision IOL, Cataract surgery
- Where
- China
- Sponsor
- Alcon Research
Aphakia Cataract
Long-Term Clinical Outcomes Of Subjects Enrolled In The RxSight Light Adjustable Lens (LAL) And Light Delivery Device (LDD) New Enrollment Study
This is an observational, follow up study of subjects previously enrolled in the "RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) New Enrollment Study".
- Trial name
- NCT07347379
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- 6 sites in United States
- Volunteers
- 108 people
- Sponsor
- RxSight, Inc.
Aphakia, Astigmatism
Evaluation of Long-term Safety and Performance of PanOptix Trifocal Intraocular Lens (IOL)
The purpose of this Post-Market Clinical Follow-up (PMCF) study is to describe the long-term safety and performance of the AcrySof IQ PanOptix IOL toric and non-toric models in subjects bilaterally implanted with these IOLs for 3…
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT06166901
- Testing
- AcrySof IQ PanOptix IOL Toric, AcrySof IQ PanOptix IOL Non-Toric
- Where
- 7 sites in Spain
- Volunteers
- 211 people
- Sponsor
- Alcon Research
Absence of Capsule Support, Aphakia
Clinical Observation of the Transscleral Suture Fixation of Posterior Chamber Intraocular Lens in Eyes With Inadequate Capsule Support
To present the follow-up outcomes of transscleral suture fixation of posterior chamber intraocular lens (PCIOL) in eyes with inadequate capsule support.
- Trial name
- NCT03817151
- Testing
- posterior chamber intraocular lens implantation
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Congenital Cataract, Microphthalmos
Biometric Characteristics of the Eye With Microcornea/Microphthalmia and Congenital Cataract Before And After Cataract Extraction
Early cataract surgery in microcornea/microphthalmia eyes is essential to prevent amblyopia and improve visual outcomes, including stereopsis.
- Conditions
- Congenital Cataract, Microphthalmos, Microcornea
- Trial name
- NCT04759560
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Alexandria University
Normal Non-fluency, Cataract
Comparative Study of the Optical Biometer for Measurements of the Eye
The primary purpose of this comparative clinical study is to collect clinical data to demonstrate the equivalence of the investigational device to the predicate device for measurements of the eye.
- Conditions
- Normal Non-fluency, Cataract, Aphakic Eye, Eyes With Corneal Abnormality
- Trial name
- NCT01729962
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Cataract, Aphakia
Evaluation of the Safety & Effectiveness of the Bausch & Lomb AKREOS® TL Intraocular Lens
This study is to evaluate the safety and effectiveness of the Bausch \& Lomb Akreos TL (thin lens) intraocular lens (IOL) following implantation in adults requiring cataract surgery.
- Trial name
- NCT00838045
- Testing
- The Bausch & Lomb Akreos TL IOL (MI60) posterior chamber IOL
- Where
- Germany
- Volunteers
- 125 people
- Sponsor
- Bausch & Lomb Incorporated