Clinical trials: Aortic Disease
Aortic Stenosis, Severe
Predictive Value of Pre-TAVI Infrahissian Conduction Time in the Occurrence of Complete Atrioventricular Block
The purpose of the study is implantation of a Pacemaker at 30 days for occurrence of a high-grade conduction disorder per- or post-procedure (yes/no)
- Trial name
- TAVHIS (NCT05714579)
- Testing
- Transcatheter Aortic Valve Implantation
- Where
- France
- Volunteers
- 35 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Aortic Valve Stenosis
The Multidisciplinary, Multimodality, But Minimalist Approach to Transfemoral Transcatheter Aortic Valve Replacement
The primary objective of this study is to determine the efficacy, safety and feasibility of next day discharge home in patients undergoing balloon-expandable transfemoral TAVR utilizing the Vancouver 3M Clinical Pathway in low…
- Trial name
- 3MTAVR (NCT02287662)
- Testing
- Vancouver 3M Clinical Pathway
- Where
- Canada
- Volunteers
- 411 people
- Sponsor
- BC Centre for Improved Cardiovascular Health
Aortic Stenosis
TAVI Without On-Site Cardiac Surgery in Poland: A Randomized Multicenter Trial Protocol
Aortic stenosis (AS) represents the most prevalent acquired valvular heart disease in European populations, and transcatheter aortic valve implantation (TAVI) has become the dominant treatment modality for patients with…
- Trial name
- NOSCAR-TAVI (NCT07515768)
- Testing
- transcathter aortic valve implantation
- Volunteers
- 404 people
- Sponsor
- Medical University of Warsaw
Thromboembolism, Bleeding
Anticoagulant After Implantation of Biological Aortic Valve Comparing With Aspirin
The optimal medical strategy for prevention of thromboembolic events after bioprosthetic aorta valve replacement (BAVR) remains controversial.
- Trial name
- NCT01452568
- Testing
- Aspirin, Warfarin
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Removal of Femoral Arterial Sheath in ICU Patients, Complete Hemostasis
Preliminary Exploration of Factors Affecting Complete Hemostasis and Supine Time After Removal of Femoral Arterial Sheath in ICU Patients
Background:Following cardiac catheterization and arterial sheath removal, manual compression is applied until bleeding stops, after which a compression belt is used.
- Conditions
- Removal of Femoral Arterial Sheath in ICU Patients, Complete Hemostasis, Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- NCT07469397
- Testing
- Direct Inspection, medical records browsing
- Where
- Taiwan
- Volunteers
- 157 people
- Sponsor
- National Taiwan University Hospital
Aortic Stenosis
The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery
This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress response: Patients undergoing aortic…
- Trial name
- NCT00348920
- Testing
- High Spinal and General Anesthesia
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Abdominal Aortic Aneurysm
TriVascular Post-Market Registry
This is a prospective observational post-market study of subjects receiving the Ovation™ or Ovation Prime™ Abdominal Stent Graft System ("Ovation™ or Ovation Prime™ Abdominal Stent Graft System Post-Market Study") in the…
- Trial name
- NCT01372709
- Testing
- Ovation™ or Ovation Prime™ Abdominal Stent Graft System
- Where
- 30 sites in Austria, Belgium and 6 more
- Volunteers
- 501 people
- Sponsor
- TriVascular, Inc.
Abdominal Aortic Aneurysm
Carbon Dioxide Guided Angiography in Endovascular Abdominal Aortic Aneurysm Repair
Endovascular aneurysm repair (EVAR) has lower short-term morbidity and mortality than open surgery. Intra-arterial contrast agents are an important component of successful EVAR as the tool of choice for preoperative evaluation of…
- Trial name
- NCT04444999
- Testing
- Carbon Dioxide Angiography
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Aortic Stenosis, Elderly Gravida
Aortic Stenosis in Elderly : Determinant of Progression
Aortic stenosis (AS) is AS is caused by calcium deposits in the aortic valve. Calcification is progressive and eventually leads to reduced leaflet motion with obstruction of the left ventricular outflow.
- Trial name
- NCT00338676
- Where
- France
- Volunteers
- 273 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aortic Aneurysm, Thoracic, Aortic Dissection
REgistRy BRAnch goRE EndopRosthEsis
Multicenter registry on patients treated by the new Gore thoracic branched endoprosthesis
- Trial name
- REBRA (NCT06276413)
- Testing
- GORE TAG Thoracic Branch Endoprosthesis
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University Hospital Padova
Cardiovascular Diseases, Heart Diseases
Aortic Calcium: Epidemiology and Progression -- Ancillary to MESA
To study the epidemiology of aortic calcium.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atherosclerosis, Coronary Arteriosclerosis
- Trial name
- NCT00059124
- Volunteers
- 1,980 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Abdominal Aortic Aneurysm
Korean Registry of Percutaneous EVAR With INCRAFT Stent Graft for the Treatment of Abdominalaortic Aneurysm (K-INCRAFT)
The sudy purpose is to investigate efficacy and safety of percutaneous endovascular aortic aneurysm repair using INCRAFT stent graft for Korean patients with abdominal aortic aneurysm.
- Trial name
- NCT03952780
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yonsei University
Abdominal Aortic Aneurysms
Endurant Bifurcated and Aorto-Uni-Iliac (AUI) Stent Graft System
To demonstrate safety and effectiveness of the Endurant Stent Graft in the treatment of Abdominal Aortic or Aorto-Uni-Iliac Aneurysms.
- Trial name
- NCT00705718
- Testing
- Endurant Stent Graft System
- Where
- 30 sites in United States
- Volunteers
- 194 people
- Sponsor
- Medtronic Cardiovascular
Cardiomyopathy, Hypertrophic
The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency
This research study is being conducted to find out how heart function and energy use differ among healthy endurance athletes, individuals who do not exercise regularly, and patients with hypertrophic cardiomyopathy.
- Trial name
- NCT04580693
- Testing
- PET Scan
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Massachusetts General Hospital
Hypertrophic Cardiomyopathy
Comparison of Data Obtained by Echocardiography and Magnetic Resonance Imaging in Hypertrophic Cardiomyopathy
Compare data (structural and functional) obtained by transthoracic rest echocardiography and magnetic resonance imaging (with gadolinium) in 30 patients with hypertrophic cardiomyopathy
- Trial name
- NCT00315783
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bicuspid-related Aortopathy, Aortic Stenosis
PRogression Of bicuSPid-rElated aoRtOpathy in Patients Undergoing Transcatheter Aortic Valve Implantation (PROSPERO-TAVI)
Transcatheter aortic valve implantation (TAVI) is being offered to younger patients affected by severe aortic stenosis as an alternative to surgery.
- Trial name
- PROSPERO-TAVI (NCT06248294)
- Testing
- CT follow-up
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Catania
Intrauterine Growth Restriction, Small-for-gestational Age
Ultrasound Evaluation of Fetal Hemodynamics and Perinatal Complications
In case of fetal weight below the 10th centile for gestational age, it is important to distinguish SGA and IUGR. SGA is defined as a fetal weight below the 10th centile.
- Trial name
- PTI'DOP (NCT03865628)
- Volunteers
- 1,200 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Aortic Stenosis
Feasibility And Safety of Early Discharge After Transfemoral Transcatheter Aortic Valve Implantation
The hypothesis behind this study is that there is a proportion of patients considered high or intermediate risk for surgery, but relatively low risk for TAVI, which can be discharged early after the procedure (within the first…
- Trial name
- FAST-TAVI (NCT02404467)
- Testing
- TF TAVI
- Where
- 10 sites in Italy, Netherlands and 1 more
- Volunteers
- 502 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
ENDOBARC-S Study: "Endovascular Branched Stent-grafts for Aortic ARCh Pathologies in Spain"
The ENDOBARC-S post-market clinical follow-up study is undertaken to evaluate the prevention of death related to aortic arch pathologies when treated by branch stent graft systems (Nexus stent-graft system®, Relay Branch® or…
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Stent-Graft Endoleak, Stent-Graft Stenosis
- Trial name
- NCT05309707
- Testing
- Endovascular exclusion
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery
Aortic Disease
Endovascular Repair of Descending ThoracoAbdominal Aortic Pathologies Using Physician Modified Endovascular Prosthesis
This is an early feasibility study that investigates the outcome of selected patients with complex thoracoabdominal aortic lesions who are suitable for endovascular (within the vessel) repair with a physician-modified Medtronic…
- Trial name
- NCT02524834
- Testing
- Exclusion of thoracoabdominal lesion, Endovascular Device Implant
- Where
- United States
- Sponsor
- Rodney A. White, MD