Clinical trials: Antioxidant Status
Overweight
Whole Grain Polyphenol Bioavailability and Effects on Health
Whole grains (WG) contain numerous physiologically bioactive compounds, a key group being polyphenolic compounds such as ferulic acid (FA).
- Trial name
- NCT01293175
- Testing
- Whole grains
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University
Periodontitis, Obstructive Sleep Apnea
Effect of Non-surgical Periodontal Treatment on Oxidative Stress and Antioxidant Status in OSAS
The main objective of this study is to compare the effect of the non-surgical periodontal treatment on serum and saliva oxidative stress parameters in patients with periodontitis and obstructive sleep apnea syndrome (OSAS) and in…
- Conditions
- Periodontitis, Obstructive Sleep Apnea, OSAS
- Trial name
- OSAS (NCT03268473)
- Testing
- Experimental, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Eczema, Atopic Dermatitis
NPQ Plus Supplementation for Skin Health and Antioxidant Status
This study evaluated the effects of NPQ Plus supplementation on skin health, antioxidant status, fatigue, and self-perceived well-being in healthy adults with skin concerns.
- Conditions
- Eczema, Atopic Dermatitis, Skin Health, Fatigue Symptom
- Trial name
- NCT07703215
- Testing
- NPQ Plus
- Where
- Malaysia
- Volunteers
- 55 people
- Sponsor
- N REMEDIER (M) SDN BHD
Chronic Subclinic Inflammation, Redox Status
Anti-inflammatory and Antioxidant Effects of Resveratrol on Healthy Adults.
This research will investigate the hypothesis that resveratrol when given orally to healthy adult smokers induces a decrease in the inflammatory and oxidative mediators which characterize the low-grade systemic inflammatory state…
- Trial name
- NCT01492114
- Testing
- Resveratrol
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Oxidative Stress, Endothelial Function
Tahini, Antioxidant Status and Endothelial Function
Cardiovascular disease (CVD), a cluster of disorders that affect heart and blood vessels, is the leading cause of morbidity and mortality around the world and is responsible for 17.9 million deaths annually worldwide.
- Conditions
- Oxidative Stress, Endothelial Function, Blood Pressure, Arterial Stiffness
- Trial name
- NCT04608747
- Testing
- Tahini
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Periodontal Diseases, Gingival Diseases
Asprosin and Total Antioxidant/Oxidant Status in Diabetes and Periodontal Disease
The goal of this observational study is to learn about how different periodontal health status affects the levels of asprosin (a hormone) and total oxidant/antioxidant status in the gingival crevicular fluid and blood serum of…
- Conditions
- Periodontal Diseases, Gingival Diseases, Type 2 Diabetes
- Trial name
- NCT07691060
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
MAFLD, Fatty Liver
Impact of Ganoderma Lucidum on NRF2 Levels and Antioxidant Status in Metabolic Asscociated Fatty Liver Disease (GL-MAFLD-NRF2 Study)
This RCT investigates the impact of Ganoderma lucidum on antioxidant staus, NRF2 levels and lipid metabolism in individuals with Metabolic Associated Fatty Liver Disease.
- Conditions
- MAFLD, Fatty Liver, Fatty Liver, Non-alcoholic Fatty Liver Disease, NAFLD, Fatty Liver, Nonalcoholic
- Trial name
- GL-MAFLD-NFR2 (NCT07564947)
- Testing
- Ganoderma lucidum
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Agriculture, Peshawar
Athletic Performance, Oxidative Stress
Ergogenic and Antioxidant Effects of Corinthian Currant
The purpose of the present study is to investigate the effect of pre-exercise supplementation of Corinthian currant on metabolism, performance and blood redox status during, and after an acute bout of prolonged exercise.
- Conditions
- Athletic Performance, Oxidative Stress, Inflammation
- Trial name
- NCT03288064
- Testing
- Corinthian currant, Glucose drink, Water ingestion
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Interstitial Lung Diseases, Sarcoidosis
The Occurence of Inflammation and Oxidative Stress in Lung Diseases
Reactive oxygen species (ROS) are suggested to play a pivotal role in ILD. Little is known, however, about the endogenous antioxidant levels in ILD that can offer protection against ROS.
- Conditions
- Interstitial Lung Diseases, Sarcoidosis, Idiopathic Pulmonary Fibrosis, COPD
- Trial name
- NCT00512967
- Where
- Netherlands
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Antioxidant Capabilities, Inflammation Biomarkers
Effects of Opuntia Ficus-indica Supplementation on Antioxidant Status and Inflammation Levels
The goal of this clinical trial is to learn if supplementation Opuntia ficus-indica improve the antioxidant status and inflammation levels of the participants. The main questions it aims to answer are: 1.
- Trial name
- NCT06657963
- Testing
- Opuntia ficus-indica Supplementation
- Where
- Malaysia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- LifeTree Asia Sdn Bhd
Burns
Antioxidant Status During Burn Rehabilitation
It is believed that children with a prior history of significant burn injury continue to manifest low levels of antioxidants well into their convalescence.The purpose of this study is to examine malondialdehyde (an oxidative…
- Trial name
- NCT00536822
- Sponsor
- Shriners Hospitals for Children
Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation
NAC Supplementation and Soccer Specific Performance
In this investigation the investigators utilized NAC supplementation to boost GSH availability during an one-week-microcycle consisting of three soccer games, in order to test the hypotheses that: i) antioxidant supplementation…
- Conditions
- Skeletal Muscle Damage, Exercise-induced Aseptic Inflammation, Skeletal Muscle Performance, Antioxidant Status
- Trial name
- NCT04523675
- Testing
- N-acetylcysteine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Oxidative Stress, Atherosclerosis
Effect of Short-term Annatto Carotenoids Supplementation on Oxidative Stress Status in Healthy Individuals
Low-density lipoprotein (LDL) oxidation has a pivotal role in atherosclerosis development. There is a relationship between carotenoids serum concentration and cardiovascular (CV) benefits, mainly in oxidized LDL (oxLDL)…
- Trial name
- NCT03820245
- Testing
- Bixin, Norbixin, Lycopene
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Oxidative Stress
Comparison of Oxidants and Antioxidants in Breastmilk Under Different Anesthesia Protocols
The goal of this observational study is to determine in women undergoing cesarean section if total oxidant status and total antioxidant status in breastmilk taken at the 6th hour postoperatively changes between general and…
- Trial name
- NCT06811714
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duzce University
Satellite Cells, Redox Status
Redox Regulation of Satellite Cells and Skeletal Muscle Healing
Skeletal muscle stem cells (Satellite cells) are indispensable for muscle growth and remodeling following myofibril damage. Skeletal muscle trauma is present in numerous catabolic conditions, characterized by elevated proteolysis…
- Conditions
- Satellite Cells, Redox Status, Exercise-induced Muscle Trauma, Aseptic Inflammation
- Trial name
- NCT03711838
- Testing
- N-Acetylcysteine
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Total Knee Arthroplasty, Tourniquet-Induced Ischemia-Reperfusion Injury
The Effect of Propofol Infusion on Total Antioxidant Status During Tourniquet-Induced Ischemia-Reperfusion Injury
The release of tourniquet produces reactive oxygen species which can cause injury. Propofol is chemically similar to phenol-based free radical scavengers.
- Trial name
- NCT01638624
- Testing
- Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Diskapi Teaching and Research Hospital
Opioid Addiction
MEDiterranean Diet-driven Detoxification of OPioid Addicted patiEnts (MED-DOPE)
The MED-DOPE (MEDiterranean diet-driven Detoxification of OPioid addicted patiEnts) study is a randomized controlled trial that aims to investigate the role of a nutritional intervention based on the principles of Mediterranean…
- Trial name
- MED-DOPE (NCT07022782)
- Testing
- A nutritional intervention based on the principles of Mediterranean diet
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristidis Veskoukis
VATS, Video Assisted Thoracoscopic Surgery
Oxidative Stress Effects of TIVA, CIVA, and Balanced Anesthesia in VATS
The primary objective of our study is to compare the effects of total intravenous anesthesia (TIVA), combined intravenous-volatile anesthesia (CIVA), and balanced anesthesia (BAL) methods on perioperative oxidative stress…
- Trial name
- NCT07271472
- Testing
- Total Intravenous Anesthesia (TIVA) Group, Balanced Anesthesia (BAL) Group, Combined Intravenous Volatile Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Menopause, Nutritional Intervention
Short-term Supplementation, Bone Turnover and Antioxidant Status in Menopause
This is a 8-week, double-blinded, placebo-controlled, randomized intervention trial to investigate the effects of Mg and Zn supplementation on antioxidant status and bone hormonal parameters.
- Conditions
- Menopause, Nutritional Intervention, Bone Diseases
- Trial name
- NCT03672513
- Testing
- Zinc Supplement, Magnesium supplement
- Where
- Spain
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Male Infertility
Effect of Two Doses of Coenzyme Q10 on Seminal Fluid and Semen Antioxidant Status
The study was conducted to assess the impact of two doses of coenzyme Q10 on seminal fluid parameters and antioxidant status in infertile men.
- Trial name
- NCT03850561
- Testing
- Coenzyme Q10 200, Coenzyme Q10 400
- Where
- Iraq
- Volunteers
- 65 people
- Sponsor
- University of Sumer