Clinical trials: Antioxidant Status
Parkinson Disease
Effect of Aerobic Training on Oxidative Stress Markers in Patients With Parkinson's Disease
Parkinson's disease is a chronic, neurodegenerative disorder characterized with the loss of dopamine-producing neurons. This loss is likely to be related with several environmental and genetic factors.
- Trial name
- NCT05511402
- Testing
- Exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Saglik Bilimleri Universitesi
Chronic Spontaneous Urticaria (CSU)
Effects of Diet and Oxidative Stress on Disease Severity and Response to Omalizumab in Chronic Spontaneous Urticaria
Chronic spontaneous urticaria (CSU) is an immune-mediated skin disorder characterized by pruritic wheals and/or angioedema. This study aims to evaluate the relationship between diet-derived antioxidant capacity and oxidative…
- Trial name
- NCT07431658
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Asthma, Wheezing
Evaluation of Toxic Metals, Trace Elements and Total Antioxidant Activity in Children With Recurrent Wheezing
The purpose of this study is to evaluate hair trace elements and toxic metals and plasma total antioxidant activity in children with recurrent wheezing and to evaluate whether these toxic metals and trace elements have any impact…
- Trial name
- NCT00749528
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Kecioren Education and Training Hospital
Vitamin D Deficiency
Effects of Vitamin D3 Supplementation on Antioxidant Enzymes Status in Vitamin D3 Deficient Asthma COPD Overlap (ACO) Patients
Asthma-COPD overlap (ACO) is a new entity in the world of respiratory ailments. The respiratory tract of these patients are continuously exposed to oxidants (due to cigarette smoking) causing oxidative stress.
- Trial name
- NCT03931889
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Oxidative Stress
Monitoring Antioxidant/Redox Status at Concordia (MARS-C)
The European Space Agency (ESA) runs a research centre in Antarctica as an earth-based model for long duration deep-space missions.
- Trial name
- MARS-C (NCT04197193)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Metabolic Syndrome
A 4-month Intervention of Antioxidant Supplementation in Overweight Children
In obese children, low antioxidant vitamin intake and reduced antioxidant capacity are common. Weight reduction reduces subclinical inflammation in obese subjects, and, similarly, antioxidant vitamins have been shown to reduce…
- Trial name
- NCT01316081
- Testing
- Vitamin C Vitamin E Selenvital all from Burgerstein Vitamine
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Swiss Federal Institute of Technology
Healthy
Effects of Water-soluble Olive Extract Supplementation
Six weeks of supplementation of an olive extract will: Improve antioxidant status Reduce inflammation Reduce muscle damage Improve exercise performance Improve exercise recovery as compared to a placebo.
- Trial name
- NCT01113827
- Testing
- Olive Extract
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Contraception
Oral Versus Patch Hormonal Contraceptive Effects on Metabolism, Clotting, Inflammatory Factors and Vascular Reactivity
The purpose of this study is to compare the effects of oral versus patch administration of hormonal contraception on hormone sensitive proteins such as lipoproteins, clotting factors and inflammatory proteins as well as blood…
- Trial name
- NCT00439972
- Testing
- Ortho-Cyclen (R), Ortho Evra (R), extended use of Ortho Evra (R)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Washington
Age Related Macular Degeneration
The Potential Role of Dietary Antioxidant Capacity on Age-Related Macular Degeneration
Including eye health, nutrition plays a vital role for the sustainability of individuals health life. There is an increasing global concern about the issues related with eye health.
- Trial name
- NCT03326401
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Hacettepe University
Muscle Damage, Oxidative Stress
The Effect of Antioxidant Vitamin Supplementation on Muscle Performance and Redox Status After Eccentric Training
Consumption of vitamin supplements is a common practice among athletes or people participating in health promoting exercise programs.
- Conditions
- Muscle Damage, Oxidative Stress, Hemolysis
- Trial name
- NCT01290458
- Testing
- Antioxidant vitamins
- Where
- Greece
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Overweight , Obesity, Antioxidant Status
Impact of Antioxidant-rich Supplementation on Skin Carotenoids Status, Antioxidant Status and Cardiometabolic Health in Overweight and Obese Individuals
This study aims to evaluate the effects of antioxidant-rich supplementation on skin carotenoid status, antioxidant status, and cardiometabolic health in overweight and obese individuals.
- Trial name
- NCT07748468
- Testing
- Antioxidant-rich supplementation Element, Antioxidant-rich supplementation Optimal
- Where
- Singapore
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Sleeping Disorders
Effects of Sesamin on Sleep Quality and Antioxidative Status
Sesame recognized as a common healthy food. Sesamin is extracted from sesame and has high antioxidant capacity which is commonly added in functional foods.
- Trial name
- NCT05678439
- Testing
- sesame extract
- Where
- 2 sites in Taiwan
- Volunteers
- 33 people
- Sponsor
- Taipei Medical University
Hepatitis C, Oxidative Stress
Blood Antioxidant Status in Chronic Hepatitis C Patients Before and After Antioxidant Supplementation: a Randomized Clinical Trial
The objective of the present study is to evaluate the antioxidant status in the blood of HCV patients treated with pegylated interferon (2a 1.5 ug/kg; 2b 180 ug) combined with ribavirin (1000 to 1250 mg) before and after…
- Trial name
- HepCAntSup (NCT00983164)
- Testing
- Antioxidant Supplementation
- Where
- 3 sites in Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade do Sul de Santa Catarina
Immune Surveillance, Stem Cell Surveillance
Rapid Effects on Antioxidant Status, Immune Alertness, and Regenerative Activity
This clinical study aims at documenting rapid effects after consuming single doses of test product, when compared to consuming a placebo. A double-blind, placebo-controlled, cross-over study design will be used.
- Trial name
- NCT07142720
- Testing
- A low dose of seaweed extract, A high dose of seaweed extract
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Natural Immune Systems Inc
Blood Transfusion Complication, Oxidative Stress
Study the Effect of Blood Transfusion on Oxidant-antioxidant Status in Term and Near-term Neonates
Primary aim is to evaluate the effect of blood transfusion on oxidant-antioxidant status in premature neonates. Secondary aim is to assess the effect of the age of transfused red blood cells on the biological markers of oxidative…
- Trial name
- NCT03767361
- Testing
- packed red blood cells transfusion
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Rania Ali El-Farrash
Thyroidectomy, Oxidative Stress
Opioid-Free Versus Opioid-Based Anesthesia in Thyroid Surgery
This study will compare opioid-free anesthesia and opioid-based anesthesia in adult euthyroid patients undergoing elective thyroidectomy.
- Conditions
- Thyroidectomy, Oxidative Stress, Anesthesia
- Trial name
- OFA-OBA (NCT07864155)
- Testing
- Fentanyl (IV), Dexmedetomidine and lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Malatya Egitim Ve Arastirma Hastanesi
Immune Thrombocytopenia
Oxidant Status and Effect of Antioxidant in Immune Thrombocytopenia
Oxidative stress occurs as a result of increased activity of free radical-producing enzymes, decreased activity of free radical-removing enzymes, and insufficient levels of antioxidants.
- Trial name
- ITP (NCT01763658)
- Testing
- Antox tablets(Mepaco), drug therapy for ITP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Amyotrophic Lateral Sclerosis
Mitochondrial Functions and Oxidative Stress in ALS Patients
In Amyotrophic Lateral Sclerosis (ALS), malnutrition is frequent (16 to 50 % of the patients) and is an independent prognostic factor.
- Trial name
- NCT00331812
- Testing
- Mitochondrial functions and oxidative stress
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Coronary Artery Disease, Diabetes
Benefits of Eggs in Combination With a Plant-based Diet
The main objective of the study is to demonstrate that the inclusion of eggs to a plant-based diet will not increase the risk for heart disease but will increase the concentration of lutein and zeaxanthin, two important…
- Conditions
- Coronary Artery Disease, Diabetes, Metabolic Syndrome
- Trial name
- NCT04234334
- Testing
- Consume 2 eggs with spinach per day, Egg Subsitute with spinach per day
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Iron Deficiency (Without Anemia)
Effect of Ferrous iROn and cUrcumin sTatus on Inflammatory and Neurotrophic markErs
INTRODUCTION: Iron is a vital nutrient for many physiological processes including DNA production, oxygen transport and neuronal processes.
- Trial name
- Fe-ROUTINE (NCT04465851)
- Testing
- Ferrous Sulphate 65 mg, Curcumin, Ferrous Sulphate 18mg
- Where
- United Kingdom
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Westminster