Clinical trials: Antibiotic-Associated Diarrhea
Antibiotic-associated Diarrhea
The Effect of a Multispecies Probiotic on Reducing the Incidence of Antibiotic-associated Diarrhoea in Children.
In this trial, the investigators aim to assess the effectiveness of a multispecies probiotic consisting of 2 strains of Bifidobacterium (B. bifidum W23, B. lactis W51) and 6 strains of Lactobacillus (L. acidophilus W37, L.
- Trial name
- NCT03334604
- Testing
- Multispecies probiotic
- Where
- 6 sites in Netherlands, Poland
- Volunteers
- 350 people
- Sponsor
- Medical University of Warsaw
Antibiotic-associated Diarrhea, Diarrhea
The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran
The Impact of Zinc and Probiotics in Preventing Pediatric Antibiotic-Associated Diarrhea in Southern Iran
- Trial name
- AAD (NCT06665503)
- Testing
- Zinc Supplement, probiotic
- Where
- Iran
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Hormozgan University of Medical Sciences
Antibiotic-Associated Diarrhea
Effect of a Fresh Fermented Dairy Drink Product Consumption on Antibiotic Associated Diarrhea and Gastro-Intestinal Disorders
The purpose of this clinical study is to evaluate the effect of a four-week consumption of a fresh fermented dairy drink containing probiotic strains on Antibiotic-Associated Diarrhea and Gastro-Intestinal disorders in adult…
- Trial name
- NCT02900196
- Testing
- 1 - Fermented dairy drink, 2 - Acidified dairy drink
- Where
- Germany
- Volunteers
- 136 people
- Sponsor
- Danone Global Research & Innovation Center
Antibiotic-associated Diarrhea
Bacillus Particles Prevent Children Antibiotics Associated Diarrhea
This prospective, multicenter, randomized, double-blind, placebo-controlled clinical study, into the group of children in the hospital that use clinical antibiotics from one month to three years old，by observing the given…
- Trial name
- NCT02993419
- Testing
- Bacillus licheniformis Intervention
- Volunteers
- 480 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
Antibiotic-associated Diarrhea
Mechanisms of Probiotics and Antibiotic-Associated Diarrhea
The focus of the study is to better understand the mechanisms causing antibiotic-associated diarrhea (AAD) and how probiotics may prevent some of the iatrogenic effects of antibiotic medications.
- Trial name
- OURBIOTIC (NCT04414722)
- Testing
- Amoxicillin-Clavulanate 875 Mg-125 Mg Oral Tablet, BB-12, Control Yogurt
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Human Gut Microbiota
Effects of Pre-, Pro- & Anti-biotics on Gut Microbiota
The purpose of this study is to compare and contrast the effects of a prebiotic (Trametes Versicolor), a probiotic (Saccharomyces boulardii) and an antibiotic (amoxicillin) on the gut microbiota of healthy volunteers.
- Trial name
- NCT01414010
- Testing
- Trametes versicolor extract, Saccharomyces boulardii, Amoxicillin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Antibiotic Associated Diarrhea
Effect of a Lacidofil® STRONG in Healthy Adults Taking Antibiotic Treatment
The objectives of this study are to evaluate stool consistency and stool frequency during and up to 8 weeks following a 7 day antibiotic treatment with Amoxicillin/Clavulanic Acid 875mg BID.
- Trial name
- NCT01941160
- Testing
- Lacidofil® STRONG
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Antibiotic-associated Diarrhoea
Effect of Probiotic Formula on Reducing the Risk for Antibiotic-associated Diarrhoea
Antibiotic treatment disturbs the balance of the intestinal microbiota and predisposes to antibiotic associated diarrhea. Previous studies have shown that the risk of developing diarrhea during a course of antibiotics may be…
- Trial name
- NCT01596829
- Testing
- Probiotic
- Where
- Finland
- Volunteers
- 258 people
- Sponsor
- Danisco
Diarrhea, Clostridium Difficile
Probiotics in the Prevention of Antibiotic Induced Diarrhea and Clostridium Difficile Associated Diarrhea.
The objective of this study is to determine the efficacy of probiotics containing 25Bn (billion) CFU (colony-forming unit) of Lactobacillus rhamnosus, Sacchromyces boulardii and Bifidobacterium breve in the prevention of…
- Trial name
- NCT03647995
- Testing
- Probiolife by Green Made (Pharma M)
- Where
- Lebanon
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yara El Helou
Nosocomial Pneumonia, Ventilator Associated Pneumonia
Characteristics of Lower Respiratory Tract Escherichia Coli Isolates in Mechanically Ventilated Intensive Care Patients
Prospective, multicenter observational study to collect Escherichia coli (E. coli) isolates originating from mechanically ventilated intensive care unit (ICU) patients; in order to characterize phenotype and genotype of E.
- Conditions
- Nosocomial Pneumonia, Ventilator Associated Pneumonia, Escherichia Coli Infections, Escherichia Coli Pneumonia
- Trial name
- COLOCOLI (NCT03303937)
- Volunteers
- 289 people
- Sponsor
- Hôpital Louis Mourier
Diarrhea
Recombinant Human Lactoferrin Administered Orally for the Prevention of Antibiotic Associated Diarrhea in Adult Patients
The purpose of the study is to Evaluate the Efficacy and Safety of Recombinant Human Lactoferrin Administered Orally for the Prevention of Antibiotic Associated Diarrhea in Adult Patients.
- Trial name
- NCT01382199
- Testing
- Lactoferrin
- Volunteers
- 340 people
- Sponsor
- Ventria Bioscience
Clostridium Difficile
Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain
The aim of this study was to analyze whether the use of the LP299v strain reduces the risk of Clostridium difficile infection (CDI) among patients receiving antibiotics and hospitalized in the nephrology and transplantation ward.
- Trial name
- NCT03368105
- Testing
- Prevention of C. difficile infections using LP299v strain
- Volunteers
- 300 people
- Sponsor
- Medical University of Silesia
Antibiotic-associated Diarrhea
Dose Response Effect of Probiotics for the Prevention of Antibiotic-associated Diarrhea in Chinese Adults
The purpose of this study is to determine the dose response effect of probiotic capsules for the prevention of antibiotic-associated diarrhea (AAD).
- Trial name
- NCT01143623
- Testing
- Probiotic
- Where
- China
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Ventilator Associated Pneumonia, Infections
Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial
Probiotics are commercially available live bacteria thought to have health benefits when ingested. A literature review of probiotic studies in the intensive care unit (ICU) found that in patients who receive probiotics, there is…
- Conditions
- Ventilator Associated Pneumonia, Infections, C-Difficile, Antibiotic-associated Diarrhea
- Trial name
- PROSPECT (NCT02462590)
- Testing
- L. rhamnosus GG - Probiotic
- Where
- 44 sites in United States, Canada and 1 more
- Volunteers
- 2,650 people
- Sponsor
- McMaster University
Antibiotic-Associated Diarrhea, Clostridium Difficile
Efficacy of Loperamide for C. Difficile Colitis and Other Diarrheal Diseases Associated With Antibiotic Therapy
To determine whether symptomatic treatment of the diarrhea in CDAD reduces morbidity and mortality of this serious nosocomial infection in patients who have antibiotic-associated diarrhea. Both C.
- Trial name
- loperamide (NCT00591357)
- Testing
- loperamide
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Fecal Microbiota Transplantation, Antibiotic-associated Diarrhea
Clinical Study of Fecal Microbiota Transplantation in the Treatment of Antibiotic-associated Diarrhea
Antibiotic-associated diarrhea (AAD) refers to the occurrence of other unexplained diarrhea symptoms after the use of antibiotics, often combined with abdominal pain, bloating and bloody stool.
- Trial name
- NCT05990972
- Testing
- Fecal Microbiota Transplantation
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Shanghai 10th People's Hospital
Antibiotic-associated Diarrhea, Clostridium Difficile
Probiotic Saccharomyces Boulardii for the Prevention of Antibiotic-associated Diarrhoea
When patients in hospitals receive antibiotics they often develop diarrhoea. The consequences may be grave for the patient. Thus far, no preventive measure is available.
- Conditions
- Antibiotic-associated Diarrhea, Clostridium Difficile, Diarrhea
- Trial name
- SacBo (NCT01143272)
- Testing
- Saccharomyces boulardii
- Where
- 14 sites in Germany
- Volunteers
- 477 people
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Antibiotic-Associated Diarrhea
Probiotics at the Treatment of Antibiotic Associated Diarrhea
The purpose of this study is to know the efficacy of the treatment with probiotics, Lactobacillus casei and Bifidobacterium breve, on clinical evidences and occurence of relapses on antibiotic-associated diarrhea.
- Trial name
- NCT00700557
- Testing
- Probiotics - Lactobacillus casei and Bifidobacterium breve, Maize starch
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of Uberlandia
Antibiotic Associated Diarrhea, Upper Respiratory Tract Infection
Effectiveness of Saccharomyces Boulardii in Prevention of Antibiotic Associated Diarrhea
Antibiotic-associated diarrhea (AAD) is a common adverse effect in pediatric patients receiving broad-spectrum antibiotics such as co-amoxiclav for upper respiratory tract infections (URTI).
- Trial name
- NCT07785206
- Testing
- Co-amoxiclav, Saccharomyces boulardii
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Clostridium Difficile
AssessmeNT of the Incidence of Clostridium Difficile Infections in Hospitalized Patients on Antibiotic TrEatment
During or after antibiotic treatment, antibiotic residues impair the intestinal microbiota (gut flora) and lead to adverse effects such as the emergence of bacterial resistance or the occurrence antibiotic-associated diarrhoea…
- Trial name
- ANTICIPATE (NCT02896244)
- Testing
- no intervention
- Where
- 34 sites in France, Germany and 4 more
- Volunteers
- 1,007 people
- Sponsor
- MJM Bonten