Clinical trials: Ankle Fracture
Foot Fusion
Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions
STUDY OBJECTIVES: Demonstrate equivalent clinical and radiologic outcomes to the "gold standard" (ABG) in a representative clinical model (hindfoot and ankle fusions) STUDY HYPOTHESIS: Augment® Bone Graft is an equivalent bone…
- Trial name
- NCT00583375
- Testing
- Augment® Bone Graft, Standard of Care
- Where
- 37 sites in United States, Canada
- Volunteers
- 414 people
- Sponsor
- BioMimetic Therapeutics
Hip Fractures, Tibial Fractures
Go Fit Fast, Recovery Trajectory Using PROMIS®, Linking PROMIS®
Prospective data will be collected in approximately 3500 patients (700 per 5 injury groups). Patients will be followed up according to the standard (routine) for up to 1 year after the treatment.
- Conditions
- Hip Fractures, Tibial Fractures, Ankle Fractures, Humeral Fracture, Proximal
- Trial name
- NCT04113044
- Testing
- All treatments will remain the standard (routine) care procedures based on individual clinician's judgment and the patient characteristics.
- Where
- 15 sites in United States, Austria and 4 more
- Volunteers
- 1,500 people
- Sponsor
- AO Innovation Translation Center
Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar
Use of Weightbearing Radiographs to Determine Treatment of bi- and Trimalleolar Ankle Fractures
The aim of this study is to evaluate the outcomes after non-operative treatment of weightbearing stable bi-and trimalleolar ankle fractures.
- Trial name
- NCT05765929
- Testing
- Non-operative treatment
- Where
- Norway
- Volunteers
- 29 people
- Sponsor
- Ostfold Hospital Trust
Postieror Malleolar Fracture, Treatment
Comparative Study of Postieror Ankle Fracture
To compare the clinical efficacy of open reduction and internal fixation (ORIF) with plate and screw for postieror malleolar fractures.
- Trial name
- NCT03064386
- Testing
- Plate fixation, Screw fixation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Fracture of Ankle
Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block
Patients scheduled to have foot and ankle surgery will typically receive a single shot sciatic nerve block to serve as the primary anesthetic and as part of a multi-modal post-operative analgesic plan.
- Trial name
- NCT01616173
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Ankle Fractures
Intramedullary Nailing Versus Plate Fixation of Ankle Fractures. A Prospective, Randomized Controlled Trial.
The purpose of this study is to make a survey of functional outcome, radiological outcome and complication rate after intramedullary nailing (IMN) and plate fixation of Weber B ankle fractures in elderly patients, and contribute…
- Trial name
- NCT03377205
- Testing
- Compression screws and neutralization plate, Acumed Fibular Rod System
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Ankle Fractures, Posterior Malleolus Fractures
Single-Window Versus Two-Window Posterolateral Approach for Malleolar Fractures
The purpose of this prospective clinical trial is to compare the clinical outcomes and early complication rates of two different surgical techniques used during the posterolateral approach for ankle fractures.
- Conditions
- Ankle Fractures, Posterior Malleolus Fractures, Lateral Malleolus Fracture
- Trial name
- NCT07481266
- Testing
- Single-Window Posterolateral Approach, Two-Window Posterolateral Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- muhammed kılıç
Edema
Effective Treatment of Posttraumatic and Postoperative Edema
Edema control after ankle- and hindfoot fractures is important. Multi-layer compression bandages or A-V Impulse compression may are more effective in reducing edema than ice.
- Trial name
- NCT01389089
- Testing
- ice gel pack, Multi-layer compression bandage, A-V Impulse compression
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- Luzerner Kantonsspital
Syndesmotic Injury of the Ankle
Tightrope or Screw Fixation of Acute Tibiofibular Syndesmotic Injury
Syndesmotic injuries are common and often associated with unstable ankle fractures. The most common treatment is with a syndesmotic screw through the fibula and tibia which is later removed, usually after 10-12 weeks.
- Trial name
- TIGHTROPE-SS (NCT01275924)
- Testing
- Tightrope Syndesmosis Repair Kit, Syndesmotic screw
- Where
- 2 sites in Norway
- Volunteers
- 97 people
- Sponsor
- Sykehuset Asker og Baerum
Ankle Fractures
RCT Comparing Non-operative vs Operative Treatment of Suprasyndesmotic Ankle Fractures.
Weight-bearing radiographs will be used to evaluate the stability of suprasyndesmotic ankle fractures. Patients with stable fractures will be randomised to operative or non-operative treatment.
- Trial name
- NCT04615650
- Testing
- Surgical treatment, Ankle orthosis
- Where
- 4 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
Ankle Injuries
Intraoperative Three Dimensional Fluoroscopy Compared to Standard Fluoroscopy for the Assessment of Reduction of Ankle Fractures With Syndesmosis Disruption
Ankle fractures are common injuries that are being operated routinely. In order to restore the long term function and prevent arthritis of the ankle the broken fragments should be put in place precisely.
- Trial name
- NCT00556010
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
Open Tibia Fracture, Open Dislocation of Ankle
Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries
The goal of this randomized controlled trial is to determine if accelerated flap coverage compared to standard flap coverage timing leads to improved infection-related complications in patients with open fractures and/or…
- Conditions
- Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
- Trial name
- FLAP ATTACK (NCT07828613)
- Testing
- Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
- Where
- 31 sites in United States
- Volunteers
- 356 people
- Sponsor
- Johns Hopkins University
Ankle Fractures, Surgery
Immediate Weight-Bearing Ankle Study
This single-centre historical control group comparative study will compare outcomes of surgically-treated rotational ankle fractures and the current routine practice of early protected weightbearing and range of motion with…
- Trial name
- NCT03032653
- Testing
- Late Rehabilitation, Early Rehabilitation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Fraser Orthopaedic Research Society
Ankle Fracture - Lateral Malleolus
Surgical Versus Conservative Treatment of Weber B1 Fracture: Functional Outcome Using Gait Analysis
The decision whether to operate an ankle fracture or not is often highly dependent on the surgeon's individual judgment. There is consensus that non-displaced Weber A-type fractures rarely require operative treatment, and that…
- Trial name
- WEBER (NCT03539029)
- Testing
- Surgery, Conservative treatment
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University Hospital, Basel, Switzerland
Ankle Fractures
Cryotherapy Reduces Time to Surgery and Local Complication in Patients With Ankle Fractures
Ankle fractures are common injuries and cryotherapy is routinely used to reduce pain, swelling and local skin complications, both before and after surgery. However, the results on ankle surgery are contradictory.
- Trial name
- Cryotherapy (NCT06396364)
- Testing
- Cryotherapy
- Where
- 2 sites in Italy
- Volunteers
- 169 people
- Sponsor
- Azienda Ospedaliera San Camillo Forlanini
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Ankle Fracture
Early Weight Bearing for Unstable Ankle Fractures Undergoing Operative Stabilization
The purpose of this randomized, controlled trial is to estimate the safety of early weight bearing on post ankle surgery. Patients who are indicated to have surgery for unstable ankle fractures by an attending trauma physician…
- Trial name
- NCT02779244
- Testing
- Early Weight bearing + Cam Boot, Non-Weight Bearing + Cam Boot
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- NYU Langone Health
Ankle Fracture Requiring Internal Fixation
Midds Ankle Fracture
The geko™ device is indicated for the prevention and treatment of oedema. The aim of this study is to show that recruiting, and performing study assessments in ankle fracture patients requiring surgery to fix their ankle…
- Trial name
- NCT02841007
- Testing
- geko neuromuscular electrostimulation device
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Firstkind Ltd
Distal Fibula Fracture
Fibular Fixation in Ankle Fractures:Plate Verses Nail.
The primary objective of this study will be to evaluate the functional outcome of patients who present with a distal fibula fracture who were treated with either intermedullary nail (IMN) fixation or plate fixation.
- Trial name
- NCT02507193
- Testing
- Open reduction internal fixation, Intermedullary Nail
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Orlando Health, Inc.
Post Operative Treatment After Unstable Malleolar Fractures
Early Protected Full Weight-bearing vs. Partial Weight-bearing After Surgical Fixation of Unstable Ankle Fractures, Monitored With Bio-feedback Insoles.
The purpose of this study is to compare the postoperative results after ORIF (Open Reduction Inner Fixation) with a partial weight-bearing protocol versus an early full weight-bearing protocol.
- Trial name
- NCT06023979
- Testing
- Full weight bearing, Partial weight bearing
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen