Clinical trials: Angle-Closure Glaucoma
Angle-closure Glaucoma, Minimally Invasive Glaucoma Surgery
Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study
The drainage angle in the anterior chamber of the eye mediates the outflow of aqueous humor, and pathological changes here can lead to high intraocular pressure and glaucoma.
- Conditions
- Angle-closure Glaucoma, Minimally Invasive Glaucoma Surgery, Goniosynechialysis, Goniotomy
- Trial name
- NCT06492538
- Testing
- various types of angle interventions
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Acute Ocular Hypertension Glaucoma, Intraocular Hypertension
Effect of Infusion Warming on Mannitol Infusion Pain in Patients With Acute Ocular Hypertension
Acute ocular hypertension is a common ophthalmic emergency that often requires rapid reduction of intraocular pressure. Intravenous mannitol is widely used for this purpose, but infusion-related pain and local venous irritation…
- Conditions
- Acute Ocular Hypertension Glaucoma, Intraocular Hypertension, Primary Angle-Closure Glaucoma
- Trial name
- NCT07495449
- Testing
- Infusion Warming Device, Routine Non-Warmed Mannitol Infusion
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Primary Open-angle Glaucoma, Primary Angle-Closure Glaucoma
Prevalence of Ocular Surface Disease in Malaysian Glaucoma Patients
This is a prospective, multi-centre, cross sectional observational study to determine the prevalence of ocular surface disease (OSD) in glaucoma patients, nationwide.
- Conditions
- Primary Open-angle Glaucoma, Primary Angle-Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigment Dispersion Glaucoma
- Trial name
- NCT04609345
- Volunteers
- 400 people
- Sponsor
- Santen Pharma Malaysia Sdn Bhd
Acute Primary Angle-closure Glaucoma
Corneal Densitometry in Acute Primary Angle Closure Glaucoma
Purpose: Our purpose was to investigate the laser peripheral iridotomy (LPI) induced changes in corneal densitometry in acute primary angle closure glaucoma (PACG) cases during the post-laser 1 month period.
- Trial name
- NCT04254458
- Testing
- Corneal densitometry
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ulucanlar Eye Training and Research Hospital
Glaucoma
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma
There is increasing evidence that there are genetic risk factors for several forms of glaucoma, such as glaucoma caused by pseudoexfoliation syndrome (PXF) ,primary angle closure glaucoma (PACG) and primary open-angle glaucoma…
- Trial name
- NCT03423758
- Testing
- Blood sample
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Primary Angle Closure Glaucoma
Comparison of Phaco Surgery With Goniosynechialysis Versus Trabeculectomy in Glaucoma Treatment
The goal of this clinical trial is to learn whether phacoemulsification combined with goniosynechialysis (Phaco-GSL) is as effective and safe as trabeculectomy in treating patients with primary angle-closure glaucoma.
- Trial name
- NCT06952153
- Testing
- Phacoemulsification with Goniosynechialysis, Trabeculectomy with 5FU
- Where
- Vietnam
- Volunteers
- 82 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Primary Angle Closure Glaucoma
Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy
The purpose of this study is to analysis changes in anterior segment morphology after laser peripheral lrldotomy measured by optical coherence tomography, and to evaluate treatment effectiveness
- Trial name
- NCT02279472
- Testing
- Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Xiangya Hospital of Central South University
Glaucoma, Angle-Closure
Comparison of Superior vs Nasal/Temporal Laser Peripheral Iridotomy in Primary Angle Closure
The purpose of this study is to determine if location of laser peripheral iridotomy (LPI) that is the standard of care treatment for angle closure glaucoma is related to changes in post-operative intraocular pressure (IOP)…
- Trial name
- NCT03187821
- Testing
- Laser peripheral iridotomy
- Volunteers
- 1,000 people
- Sponsor
- Venkatesh Rengaraj
Glaucoma Open-Angle, Glaucoma Eye
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register
The study is an observational analysis of patients' medical data recorded in a large-scale register, both retrospective (for patients operated and data recorded before 2018) and prospective (for data collected after 2018) in…
- Conditions
- Glaucoma Open-Angle, Glaucoma Eye, Glaucoma; Drugs, Glaucoma, Angle-Closure
- Trial name
- NCT04381611
- Where
- Switzerland
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Dr. Kaweh Mansouri
Glaucoma, Glaucoma, Open-Angle
Long Term Outcome of Combined Phacoemulsification and Excisional Goniotomy With the Kahook Dual Blade
Purpose: Characterize changes in intraocular pressure (IOP), IOP-lowering medications, and visual acuity (VA) through 3 years in patients undergoing combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Cataract, Angle Closure Glaucoma
- Trial name
- NCT04476810
- Testing
- kahook dual blade
- Where
- Saudi Arabia
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ahmed Al Habash
Ophthalmopathy, Glaucoma
Phaco-Trabeculotomy Vs Phaco-Trabeculectomy
A prospective, randomized comparative study on adult patients with synechial angle closure glaucoma.
- Conditions
- Ophthalmopathy, Glaucoma, Glaucoma, Angle-Closure
- Trial name
- PDT vs PT (NCT04683055)
- Testing
- Phacoemulsification combined with trabeculectomy, Phacoemulsificaiton combined with ab-externo trabeculotomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma
Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure Glaucoma
This study evaluates whether combining cataract surgery (phacoemulsification) with incisional goniotomy effectively lowers intraocular pressure (IOP) and reduces the need for glaucoma medications in patients with coexisting…
- Conditions
- Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma, Cataract
- Trial name
- NCT07821827
- Testing
- Combined Phacoemulsification and Goniotomy
- Volunteers
- 70 people
- Sponsor
- Assiut University
Primary Angle-Closure Glaucoma
Predicting the Risk of Partial Ciliary Block After Cataract and Goniosynechialysis Surgery in Primary Angle-Closure Disease
Primary angle-closure disease (PACD) is a major cause of vision loss, often treated with a combined surgery that removes the eye's natural lens (cataract surgery) and physically opens the eye's drainage system…
- Trial name
- PCB-Risk (NCT07549438)
- Volunteers
- 1,150 people
- Sponsor
- Peking University People's Hospital
Primary Open Angle Glaucoma (POAG), Juvenile Open Angle Glaucoma
Testing a Reading Module to Improve Reading Skills and Quality of Life in Glaucoma Patients
The goal of this interventional study is to test the effectiveness of reading rehabilitation module towards reading speed and error, and quality of life in glaucoma patients.The main questions it aims to answer are: 1.
- Conditions
- Primary Open Angle Glaucoma (POAG), Juvenile Open Angle Glaucoma, Normotensive Glaucoma, Primary Angle Closure Glaucoma
- Trial name
- NCT07741812
- Testing
- Reading Rehabilitation Module
- Where
- Malaysia
- Volunteers
- 100 people
- Sponsor
- Universiti Sains Malaysia
Glaucoma
Argon Laser Peripheral Iridoplasty for Primary Angle Closure Glaucoma
Glaucoma is the leading cause of irreversible blindness worldwide. With ageing of the population, glaucoma morbidity will rise, causing increased health care costs and economic burden for a condition in which visual loss, once…
- Trial name
- ALPI (NCT00980473)
- Testing
- Argon Laser Iridoplasty, Travatan/ Timolol/Azopt
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- Singapore National Eye Centre
Glaucoma, Acute Primary Angle-closure Glaucoma
Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma
The investigators wanted to reported the results of immediate anterior chamber paracentesis (ACP), compared to Mannitol infusion, in patients with acute primary angle-closure glaucoma (PACG).
- Trial name
- NCT01266343
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube
The investigators hypothesize that KeraSys is a safe as Tutoplast to cover the tube of the Molteno 3 glaucoma drainage device during surgery
- Conditions
- Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
- Trial name
- NCT01301378
- Testing
- Molteno 3 glaucoma drainage shunt
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wills Eye
Glaucoma, Angle-Closure
Outcome of GATT Combined With Goniosynechiolysis in Glaucoma Patients With Secondary Synechial Angle Closure.
To evaluate the intraocular pressure reduction effect of combined gonioscopy-assisted transluminal trabeculotomy (GATT) with goniosynechialysis in eyes with secondary synechial angle closure glaucoma.
- Trial name
- NCT06445634
- Testing
- Gonioscopy-Assisted Transluminal Trabeculotomy Combined with Goniosynechiolysis
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Kasr El Aini Hospital
Chronic Angle Closure Glaucoma, Primary Angle Closure
Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study
Sequential Laser Iridotomy uses argon and Nd:yag laser in the first and second steps, respectively. Using q-switched 532 nm laser in the second step is hypothesized to be as good and effective as the conventional Nd:yag laser…
- Conditions
- Chronic Angle Closure Glaucoma, Primary Angle Closure, Primary Angle Closure Suspect, Fellow Eyes of Acute Angle Closure Glaucoma
- Trial name
- NCT00452998
- Testing
- Q-switched fd Nd:yag in Laser Iridotomy
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Angle Closure Glaucoma, Glaucoma
Anterior Segment Changes by Optical Coherence Tomography (OCT) in Phaco- Trabeculectomy
1. Develop a measurement protocol by OCT imaging and characterization of the anterior chamber change in glaucoma patients before and after surgery. 2. Show the effect of combined surgery in control of intra ocular pressure.
- Conditions
- Angle Closure Glaucoma, Glaucoma, Cataract Secondary
- Trial name
- NCT03626675
- Testing
- phaco- trabeculectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University