Clinical trials: Angioplasty, open to volunteers
Takayasu Arteritis With Pulmonary Artery Involvement, Percutaneous Transluminal Pulmonary Angioplasty
Treatment of Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
1. Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement 2.
- Conditions
- Takayasu Arteritis With Pulmonary Artery Involvement, Percutaneous Transluminal Pulmonary Angioplasty, PAH Targeted Medication
- Trial name
- NCT05388682
- Testing
- Percutaneous transluminal pulmonary angioplasty
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Renal Artery Obstruction, Hypertension, Renovascular
A Prospective Danish National Registry of PTRA in Patients With Renovascular Hypertension
A prospective Danish national registry of percutaneous transluminal renal angioplasty (PTRA) in high-risk patients with renal artery stenosis selected on the basis of common national criteria, and with a common follow-up protocol…
- Conditions
- Renal Artery Obstruction, Hypertension, Renovascular, Cardiovascular Diseases, Kidney Diseases
- Trial name
- DAN-PTRA (NCT02770066)
- Testing
- Percutaneous transluminal renal angioplasty
- Where
- 5 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- University of Aarhus
Coronary Artery Disease
The PICCOLETO IX PHENO Study
To investigate whether pre-procedural OCT-derived de novo coronary lesion phenotype (lipid-rich, fibrotic, calcific; and ACS mechanisms such as plaque rupture/erosion/calcified nodule) is associated with clinical outcomes after…
- Trial name
- PIX-PHENO (NCT07390994)
- Volunteers
- 600 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
Peripheral Arterial Disease, Vascular Diseases
Road Mapping Guided Puncture Versus Ultrasound Guided Puncture During Retrograde Angioplasty Feasibility and Safety
The study aims to compare the technical feasibility and safety of road mapping-guided versus ultrasound-guided retrograde arterial puncture in patients with (CLTI) as measured by: Puncture success rate Access-related complication…
- Trial name
- NCT07427108
- Testing
- Road-map guided versus US guided retrograde access
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Sohag University
Peripheral Arterial Disease
Comparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal Lesions
This study is an investigator-initiated, prospective, single-center, 1:1 randomized pilot study. The trial evaluates the safety and efficacy of intravascular lithotripsy in comparison to standard lesion preparation using standard…
- Trial name
- CRACK-IT (NCT06112171)
- Testing
- Intravascular lithotripsy, Standard lesion preparation
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Leipzig
Tear Film Alteration
Effect of Dexmedetomidine on Tear Production in Angioplasty Patients
During medical procedures performed under local anesthesia with sedation, such as angioplasty, the eyes may become dry because normal blinking and tear production can be reduced.
- Trial name
- NCT07326332
- Testing
- Dexmedetomidine, Sedation with Midazolam, Fentanyl, and Propofol
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Benha University
Severe Lower Limb Ischemia
The Endovascular Plus GENe Therapy Versus Only EndoVascular Therapy for Severe Limb ischaemiA Trial
GENEVA is the world's first multicenter, randomized, prospective, controlled trial of the clinical effectiveness of best endovascular treatment versus best endovascular treatment combined with gene therapy for severe lower limb…
- Trial name
- NCT06473740
- Testing
- Deoxyribonucleic acid supercoiled plasmid pCMV-VEGF165 (Neovasculgen)
- Where
- Russia
- Volunteers
- 386 people
- Sponsor
- Amur State Medical Academy
Arteriovenous Fistula, Angioplasty, Balloon
DRug-coAted Balloon Compared With cuttinG balloON in Treatment of Arteriovenous Fistula Stenosis
The purpose of this clinical trial is to compare the efficacy and safety of cutting balloons versus drug-coated balloons in treating venous stenosis of autologous arteriovenous fistulas.The main questions it aims to answer are…
- Conditions
- Arteriovenous Fistula, Angioplasty, Balloon, Hemodialysis Access Failure
- Trial name
- Dragon (NCT06527963)
- Testing
- Endovascular therapy
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- RenJi Hospital
Coronary Artery Disease, Acute Coronary Syndrome
KOMATE Registry: Korean Multicenter Angioplasty Team
The investigators will enroll the patients who underwent PCI and was based on real world clinical practice to collect the data regarding demographic, clinical, procedural information and clinical outcome using case report forms.
- Conditions
- Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction, Percutaneous Coronary Intervention
- Trial name
- NCT03908463
- Testing
- Percutaneous coronary intervention
- Where
- South Korea
- Volunteers
- 20,000 people
- Sponsor
- Yonsei University
Chronic Thromboembolic Disease
BPA in CTEPD Without PH
The goal of this clinical trial is to assess the effect of Balloon Pulmonary Angioplasty (BPA) on quality of life and exercise capacity in patients with chronic tromboembolic pulmonary disease (CTEPD) without pulmonary…
- Trial name
- BALLOON (NCT06090838)
- Testing
- Balloon Pulmonary Angioplasty (BPA)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Amsterdam UMC, location VUmc
Frail Elderly Syndrome, Coronary Heart Disease
Frailty Syndrome in Daily Practice of Interventional Cardiology Ward
The impact of frailty on immediate and long term outcomes of invasive treatment of coronary artery disease is not fully characterized.
- Conditions
- Frail Elderly Syndrome, Coronary Heart Disease, Acute Coronary Syndrome, Coronary Artery Bypass Grafting
- Trial name
- FRAPICA (NCT03209414)
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Silesia
Coronary Disease, Heart Diseases
Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)
This international, multicenter, open-label, randomized clinical trial evaluates the safety and efficacy of single antiplatelet therapy (SAPT) compared to dual antiplatelet therapy (DAPT) in elderly or high bleeding risk patients…
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Myocardial Ischemia
- Trial name
- PIV-EPIC (NCT06535568)
- Testing
- Drug-coated balloon, Single antiplatelet therapy (SAPT), Dual antiplatelet therapy (DAPT)
- Where
- Italy
- Volunteers
- 576 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
Arterial Disease of Legs, Below-the-knee Obstruction
Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease
This is a Pivotal, Prospective, randomized, two arm, placebo controlled, single-blind, multicenter trial that will be conducted at approximately 80 sites; approx.
- Conditions
- Arterial Disease of Legs, Below-the-knee Obstruction, PAD - Peripheral Arterial Disease
- Trial name
- MAGICAL BTK (NCT06182397)
- Testing
- MagicTouch PTA Sirolimus drug coated balloon
- Where
- 29 sites in United States
- Volunteers
- 368 people
- Sponsor
- Concept Medical Inc.
Ischemic Stroke
Balloon angiopLasty for Intracranial Atherosclerotic Minor Stroke/TIA
The objective of this study was to evaluate the safety and efficacy of early submaximal balloon angioplasty combined with medical therapy vs medical therapy alone for minor stroke/transient ischemic attack with intracranial…
- Trial name
- NCT06014723
- Testing
- Submaximal balloon angioplasty
- Where
- China
- Volunteers
- 416 people
- Sponsor
- Shouchun Wang, MD, PhD
Interventional, Cardiology
France PCI Registry : National Observatory of Interventional Cardiology
Rigorous clinical practice assessment is a key factor to improve patient's care and prognosis in interventional cardiology (IC).
- Conditions
- Interventional, Cardiology, Angioplasty, Coronary
- Trial name
- NCT02778724
- Where
- 15 sites in France
- Volunteers
- 40,000 people
- Sponsor
- Club Régional des Angioplasticiens de la région Centre
Peripheral Artery Disease, Atherosclerosis
Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease
This study aims to conduct a randomized, double blind, randomised controlled multicentre trial of sirolimus drug coated balloon versus standard percutaneous transluminal angioplasty for the treatment of superficial and popliteal…
- Conditions
- Peripheral Artery Disease, Atherosclerosis, Arterial Disease
- Trial name
- FUTURE-SFA (NCT04511234)
- Testing
- MagicTouch PTA sirolimus drug coated balloon (DCB), POBA standard balloon
- Where
- 20 sites in Singapore, Taiwan and 1 more
- Volunteers
- 279 people
- Sponsor
- Concept Medical Inc.
PTA (Percutaneous Transluminal Angioplasty), Femoropopliteal Artery Disease
One-Year Results of GENOSS PCB Real-World Study in Femoropopliteal Artery Disease
The purpose of this study is to evaluate the long-term safety and efficacy of GENOSS PCB by enrolling and tracking patients who underwent percutaneous transluminal angioplasty using GENOSS PCB in patients with femoropopliteal…
- Trial name
- NCT07431437
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Genoss Co., Ltd.
In-Stent Coronary Artery Restenosis, Coronary Artery Disease
The PICCOLETO XI A-PREP Study
To compare the angiographic and clinical outcomes of aggressive versus standard balloon preparation during drug-coated balloon (DCB) angioplasty for in-stent restenosis (ISR).
- Trial name
- PICCOLETO-XI (NCT07391033)
- Volunteers
- 500 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
CTEPH, Pulmonary Hypertension (PH)
Arterial Wave Energy Flux and Multidimensional Recovery in Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Balloon Pulmonary Angioplasty
The goal of this observational study is to learn if advanced heart pressure wave analysis (called WIA and REPA) can help track and predict clinical improvement in adults (aged 18-85) with Chronic Thromboembolic Pulmonary…
- Trial name
- WE FIX BPA (NCT07522203)
- Testing
- Balloon Pulmonary Angioplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul Mehmet Akif Ersoy Educational and Training Hospital
Coronary Artery Disease, Percutaneous Transluminal Coronary Angioplasty
Evaluation of the First, Second, and New Drug-Eluting Stents in Routine Clinical Practice
The objective of this study is to evaluate effectiveness and safety of the new drug-eluting stent (DES), as compared with the first-,second-,third-, and fourth-generation DES, in the "real world" daily practice.
- Trial name
- IRIS-DES (NCT01186133)
- Where
- South Korea
- Volunteers
- 50,000 people
- Sponsor
- Seung-Jung Park