Clinical trials: Angioplasty
Myocardial Infarction
Senior PAMI: Primary Angioplasty Versus Thrombolytic Therapy for Acute Myocardial Infarction in the Elderly
This is a prospective, randomized, multi-center, international trial comparing two reperfusion strategies in elderly (age >= 70 years) patients with acute myocardial infarction: primary percutaneous coronary intervention (PCI)…
- Trial name
- NCT00136929
- Testing
- Thrombolytic therapy, Percutaneous coronary intervention (PCI)
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- PAMI Coordinating Center
Contrast Induced Nephropathy
Oral Versus Intravenous Hydration to Prevent Contrast Induced Nephropathy
The increased risk for contrast-induced nephropathy (CIN) in patients with chronic kidney disease (CKD) undergoing coronary angiography (CAG) has been established.
- Trial name
- HYDRATE (NCT01093131)
- Testing
- Oral hydration, Oral sodium bicarbonate, Intravenous Hydration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Western Pennsylvania Hospital
Critical Limb Ischaemia, Claudication
Peripheral Vascular Disease and Nerve Stimulation
A study to see what effect the geko™ device has on blood flow in patients with lower limb vascular disease.
- Conditions
- Critical Limb Ischaemia, Claudication, Ulcers, Varicose Veins
- Trial name
- CCLINS (NCT01942941)
- Testing
- geko™ electrical stimulation
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Acute Myocardial Infarction, Ischemia-reperfusion Injury
Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.
Background: Acute myocardial infarction (AMI) has remained a leading cause of mortality and disability worldwide. Although percutaneous coronary angioplasty (PCA) is the best treatment for these patients, paradoxically this…
- Conditions
- Acute Myocardial Infarction, Ischemia-reperfusion Injury, Reperfusion Injury, Myocardial, Reperfusion Arrhythmias
- Trial name
- NCT05215743
- Testing
- Antioxidant therapy, NaCl 0.9%
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Chile
Coronary Artery Disease
Clinical and Angiographic Outcomes of Post-drug-coated Balloon Angioplasty in Native Coronary Lesions
The progression of cardiac revascularization techniques, starting with standard balloon angioplasty (POBA) and progressing to the creation of drug-coated balloons (DCB) and drug-eluting stents (DES).
- Trial name
- NCT06340373
- Testing
- DCB Angioplasty
- Where
- Bangladesh
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiovascular Diseases, Bangladesh
Nephropathy
A Randomized Trial of Rosuvastatin in Elective Angioplasty to Prevent Contrast-induced Nephropathy (CLEAR-CIN).
The investigators analyzed the HMG-CoA reductase inhibitor, rosuvastatin, for the prevention of contrast-medium-induced nephropathy in patients undergoing primary angioplasty.
- Trial name
- CLEAR-CIN (NCT02737319)
- Testing
- Rosuvastatin
- Where
- Brazil
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Coronary Artery Disease
Anti Ischemic Effects of Abciximab in Angioplasty and Stenting Patients
AIR STUDY TITLE: Anti-Ischemic effects of Abciximab(Reopro) PATIENT POPULATION: Patients undergoing PCI(an interventional procedure placing a small stent/metallic tube to keep a narrowed artery in your heart open) and either on a…
- Trial name
- AIR (NCT00379418)
- Testing
- Abciximab
- Where
- 2 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Emory University
Acute Kidney Injury, Percutaneous Coronary Intervention
Dapagliflozin in the Prevention of Post-Coronary Angioplasty Acute Kidney Injury
To compare the incidence of acute kidney injury (AKI) post percutaneous coronary intervention (PCI) in a Dapagliflozin treated group versus a group managed with the usual standard of care.
- Trial name
- DAPA-PCI-AKI (NCT05435235)
- Testing
- Dapagliflozin 10mg Tab
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Budd-Chiari Syndrome
Budd-Chiari Syndrome in China: Balloon Angioplasty Alone or Combined With Stent Placement?
Budd-Chiari syndrome (BCS) is defined as the hepatic outflow obstruction from the small hepatic veins to the confluence between inferior vena cava and right atrium, which often leads to the life-threatening complications, such as…
- Trial name
- NCT02201485
- Testing
- Stent, Balloon
- Where
- China
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Peripheral Artery Occlusive Disease, Percutaneous Transluminal Angioplasty
Regional Anesthesia for Percutaneous Transluminal Angioplasty
In this study, the effects of regional anesthesia method applied in patients who will undergo percutaneous transluminal angioplasty for lower extremity revascularization will be investigated comparatively.
- Trial name
- NCT05737225
- Testing
- Near Infrared Spectroscopy (NIRS)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gazi University
Coronary Artery Disease
REVEAL Study: Vessel Healing After Angioplasty
To address early vessel healing and thrombus formation after deployment of three distinct groups of stents
- Trial name
- REVEAL (NCT00799344)
- Testing
- Catania Stent
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- CeloNova BioSciences, Inc.
Peripheral Vascular Disease
JET-RANGER Trial - JETStream Atherectomy With Adjunctive Paclitaxel-Coated Balloon Angioplasty vs Plain Old Balloon Angioplasty Followed by Paclitaxel-Coated Balloon
A prospective, multicenter, randomized study evaluating the use of Jetstream Atherectomy (JS) followed by DCB in comparison to the use of plain old balloon angioplasty (POBA) followed by DCB alone in the treatment of complex…
- Trial name
- NCT03206762
- Testing
- Jetstream Atherectomy with randomization to the Ranger or IN.PACT DCB Arm or the POBA+DCB (Ranger or IN.PACT) Arm
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Midwest Cardiovascular Research Foundation
Stent Thrombosis
Long-Term Safety of Drug Eluting Stents in the "Real World" (FReIburger STent Registry)
The FReIburger STent Registry (FRIST) is designed to determine the long term safety and efficacy of Drug Eluting Stents (DES) in a "real-world" patient population requiring stent implantation.
- Trial name
- FRIST (NCT00905008)
- Testing
- transluminal percutaneous coronary intervention, Drug-Eluting and Bare-Metal stents
- Volunteers
- 1,502 people, healthy volunteers welcome
- Sponsor
- University Hospital Freiburg
Angioplasty, Balloon, Disease, Peripheral Artery
Post-market Registry to Assess the Clinical Performance and Safety of the Passeo-18 Lux in Infrainguinal Arteries
The purpose of his study is to collect short term and long term clinical evaluation data of the Passeo-18 Lux Paclitaxel releasing balloon catheter, subject to patients who visit hospital from arteriosclerosis in the…
- Trial name
- NCT05175703
- Testing
- Passeo-18 Lux Paclitaxel releasing Balloon Catheter
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Chronic Limb Threatening Ischemia
Outcomes of Atherectomy and Balloon Angioplasty Compared to Conventional Angioplasty in Infra-popliteal Chronic Limb-Threatening Ischemia
Chronic limb-threatening ischemia (CLTI) represents the most advanced stage of peripheral artery disease (PAD), characterized by rest pain, non-healing ulcers, or gangrene, and is associated with high morbidity and risk of…
- Trial name
- NCT07120555
- Testing
- atherectomy, Percutaneous transluminal angioplasty of infra-popliteal arteries lesions with primary long
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Peripheral Artery Disease
Clinical Study of Focal Implant Used for Lower Extremity Post-angioplasty Dissection
This is a prospective, multicenter, randomized controlled trail using spot stenting to treat lower extremity post-angioplasty dissection.
- Trial name
- PINTO (NCT05562076)
- Testing
- the spot stent(ZENFLEX ® Pinto) system, the bare stent( Everflex) system
- Where
- 12 sites in China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Zhejiang Zylox Medical Device Co., Ltd.
Multiple Sclerosis
Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients
This is a single center, multispecialty, randomized double blind placebo control feasibility clinical trial. The purpose is to evaluate the safety, feasibility and efficacy of percutaneous transluminal angioplasty in treating…
- Trial name
- NCT01089686
- Testing
- Venoplasty
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Manish Mehta, MD
Myocardial Infarction, Unstable Angina
Evaluation of an Introductory Videotape Intervention to Improve Cardiac Rehabilitation Participation
The purpose of this study is to determine whether a pre-discharge videotape introducing the concept and benefit of a Cardiac Rehabiliation \& Secondary Prevention (CRSP) program will increase intent to participate in a CRSP…
- Conditions
- Myocardial Infarction, Unstable Angina, Coronary Angioplasty, Coronary Artery Bypass Surgery
- Trial name
- NCT00372671
- Testing
- Survey, Survey and videotape
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease
The ATLANTA First in Man Study of the Catania Stent
To evaluate the short-term and mid-term safety and efficacy of the Catania coronary stent for the treatment of up to two de novo lesions in native coronary arteries.
- Trial name
- ATLANTA (NCT00799032)
- Testing
- PCI
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- CeloNova BioSciences, Inc.
Radial Artery
Oximetry Guided Versus Traditional Rapid Deflation Technique for Achieving Hemostasis After Radial Procedures
After performing a radial angiography/percutaneous coronary intervention (CAG/PCI), the sheath is removed and a compression device is used to achieve hemostasis.
- Trial name
- ACCESS-III (NCT03626129)
- Testing
- Oximetry guided deflation
- Where
- Denmark
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital Skejby