Clinical trials: Anger
Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders
Study of Children at Risk for Disruptive Behavior Disorders
A conduct disorder is characterized by repetitive and persistent patterns of behavior where the basic rights of others and rules are violated.
- Conditions
- Attention Deficit and Disruptive Behavior Disorders, Child Behavior Disorders, Passive-Aggressive Personality Disorder
- Trial name
- NCT00001233
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
TBI, Suicide Prevention
A Mixed Methods Pilot Trial of the STEP Home Workshop to Improve Reintegration and Reduce Suicide Risk for Recently Transitioned Veterans
Risk of Veteran suicide is elevated during the first year of transition from military service to civilian life. Most Veteran suicides occur among Veterans who are not connected to VA healthcare.
- Conditions
- TBI, Suicide Prevention, Veterans, PTSD
- Trial name
- SH-SP (NCT05995678)
- Testing
- STEP-Home-SP, Transition Assistance Program, VA Solid Start
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colonic Diseases
A Clinical Phase I Study on GIC-1001 in Healthy Volunteers
The objectives of this single center, randomized, double-blinded, placebo-controlled Phase I clinical study are to evaluate the safety and tolerability of five (5) single and four (4) multiple increasing oral doses of GIC-1001…
- Trial name
- NCT01738425
- Testing
- GIC-1001; 125 mg oral tablets
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- gicare Pharma Inc.
Healthy Volunteers
QG101-23-0 Capsules SAD and MAD Study in Healthy Subjects
The study will consist of three parts: a single-dose ascending (SAD) phase (Part A) enrolling a total of five ~ six cohorts of healthy participants, a multiple-dose ascending (MAD) phase (Part B) enrolling 3 cohorts of healthy…
- Trial name
- NCT05650528
- Testing
- QG101-23-0 capsules
- Where
- Australia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Amckaus PTY LTD.
Positional Obstructive Sleep Apnea
Economic Evaluation of Treatment Modalities for Position Dependent Obstructive Sleep Apnea
OBJECTIVES: To evaluate the effect and cost-utility of a combination therapy of SPT+MAD compared with continuous positive airway pressure (CPAP) in patients with moderate positional obstructive sleep apnea (POSA).
- Trial name
- NCT02553902
- Testing
- Sleep position trainer, Mandibular advancement device, Continuous positive airway pressure
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 200 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Chemotherapy-induced Diarrhea
A Sequential Single and Multiple Ascending Dose (SAD/MAD) Study of SK10 Powders in Healthy Adult Subjects
The purpose of this study is to assess the safety and tolerability of orally administered SK10 powders in healthy adult subjects at three dose levels, following single and multiple doses.
- Trial name
- NCT06026397
- Testing
- SK10
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Guangzhou Zhiyi Biotechnology Co., Ltd.
Depression, Anxiety
A Pychoeducational Intervention for Women With Diabetes
This proposal describes a small randomized study to determine whether usual medical care (UMC) for diabetes combined with a psychoeducational program is more effective than UMC for diabetes alone.
- Conditions
- Depression, Anxiety, Anger
- Trial name
- SWEEP (NCT01185561)
- Testing
- Psychoeducational intervention
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Loyola University
Depression, Anxiety, Anger
Building Emotional Awareness and Mental Health (BEAM) 2024-2027
Children are highly sensitive to adversity during their first five years of life, with exposure to chronic parental mental illness (MI) consistently linked to socio-emotional impairments and mental health problems in children.
- Conditions
- Depression, Anxiety, Anger, Parenting, Stress, Psychological
- Trial name
- BEAM (NCT06455397)
- Testing
- The Building Emotional Awareness and Mental Health (BEAM) Program
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Leslie E. Roos
Pain
Safety and Pharmacokinetics of SAD/MAD Oral Doses of SRP-3D (DA)
This is a two-part randomized, double-blind, placebo-controlled study.
- Trial name
- NCT05484414
- Testing
- SRP-3D (diethylamide)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South Rampart Pharma, Inc.
Healthy Volunteers
Phase 1, SAD/MAD of Verasone™ Administered by Sinonasal Irrigation in Healthy Participants
Verasone™ is an aqueous suspension of the combination of two marketed drugs to be dosed by sinonasal irrigation in the treatment of Chronic Rhinosinusitis (CRS).
- Trial name
- NCT06147921
- Testing
- Verasone
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Diceros Therapeutics
Obstructive Sleep Apnea Syndrome, Temporomandibular Disorders
Side Effects of Mandibular Advancement Devices
Sleep-related breathing disorders (SBAS) are one of the most common causes of non-restorative sleep. Sleep therapy options include positive pressure ventilation with continuous positive airway pressure (CPAP) masks, mandibular…
- Trial name
- NCT04050514
- Testing
- H-MAD with a hinge system according to Herbst
- Where
- 9 sites in Germany
- Volunteers
- 65 people
- Sponsor
- University Medicine Greifswald
Healthy
Single and Multiple Ascending Dose Study for NKTR-118 and Cross-over Study to Investigate the Effect of Food for NKTR-118 in Japanese Healthy Subjects
The purpose of this study is to evaluate the safety and tolerability of NKTR-118 with healthy subjects.
- Trial name
- Japan SMAD (NCT01318655)
- Testing
- NKTR-118
- Where
- Japan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Posttraumatic Stress Disorder
Telemedicine and Anger Management Groups With PTSD Veterans in the Hawaiian Islands
Telemedicine has the potential to profoundly influence the delivery of specialized care to the remote veteran population suffering with PTSD.
- Trial name
- NCT00122109
- Testing
- 12 sessions Anger Management Therapy.
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- US Department of Veterans Affairs
Healthy Volunteers
A Study of Orally Administered ZM-H1505R to Evaluate Safety, Tolerability and Pharmacokinetics After Single and Multiple Ascending Doses in Healthy Participants
ZM-H1505R is an investigational drug developed by Shanghai Zhimeng Biopharma Inc. for the treatment of Chronic Hepatitis B. The purpose of this study is to see how safe the study drug is and how well it is tolerated after dosing.
- Trial name
- NCT04220801
- Testing
- ZM-H1505R
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhimeng Biopharma, Inc.
Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis
A Phase 1, MAD Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LY03017
This is a phase 1，randomized, double-blind, placebo-controlled, MAD study to evaluate the safety, tolerability and pharmacokinetics of oral LPM526000133 Fumarate Capsules (LY03017) in healthy adult subjects
- Conditions
- Hallucinations and Delusions Associated With Alzheimer's Disease Psychosis, Hallucinations and Delusions Associated With Parkinson Disease Psychosis, Negative Symptoms of Schizophrenia
- Trial name
- NCT06980207
- Testing
- LY03017
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Luye Pharma Group Ltd.
Anger, Intermittent Explosive Disorder
A Pilot Study Comparing the Efficacy of Group Versus Individual Anger Management in Subjects With IED
The purpose of this study is to see how different forms of "Anger Management" compare in reducing anger and impulsive aggressive symptoms in people.
- Trial name
- NCT00127400
- Testing
- anger management therapy
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Chicago
OSA - Obstructive Sleep Apnea
BioMAD - A Non-inferiority Study
Evaluation of the effectiveness of a new mandibular advancement device (BioMAD) in the treatment of obstructive sleep apnea.
- Trial name
- BioMAD (NCT07845331)
- Testing
- BioMAD
- Volunteers
- 20 people
- Sponsor
- University of Lausanne Hospitals
Inflammatory Bowel Disease, Colitis, Ulcerative
LMT503 First-in-human SAD, MAD, and FE Study
This is a double-blind, randomized, placebo-controlled study, consisting of a single ascending dose (SAD) part with integrated food effect (FE) arm, and a multiple ascending dose (MAD) part to assess the safety, tolerability, and…
- Conditions
- Inflammatory Bowel Disease, Colitis, Ulcerative, Crohn Disease
- Trial name
- NCT05659953
- Testing
- LMT503
- Where
- Netherlands
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Lmito Therapeutics Inc.
SARS Cov 2 Vaccination in Adolescents With Juvenile Idiopathic Arthritis
SARS Cov 2 Vaccination in Adolescents With Juvenile Idiopathic Arthritis
Since june 2021, vaccination against the SARS-Cov2 virus is recommanded in France to all children from 12 to 18 years old. In the specific population of teenagers living with juvenile arthritis, the vaccine seems to be safe and…
- Trial name
- VACOVAJI (NCT05547451)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
General Population
Trait Injustice, Social Exclusion, and Anger
Participants will be randomly allocated to one of two experimental conditions: social exclusion or social inclusion. Participants, but not experimenters will be blind to the assignment. Pre- and post-tests will be administered.
- Trial name
- NCT04288908
- Testing
- Cyberball experimental task
- Where
- Spain
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I