Clinical trials: Aneurysmal Subarachnoid Haemorrhage
Aneurysmal Subarachnoid Hemorrhage
The Optimal Dose of Mannitol for Intraoperative Brain Relaxation During the Operation of Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) tended to lead to a sudden increase in intracerebral pressure (ICP), which can cause decreased cerebral perfusion and transient global cerebral ischemia.
- Trial name
- ODAS (NCT04135456)
- Testing
- Mannitol
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Hemorrhage, Subarachnoid Hemorrhage, Aneurysmal
Prevention of Vasospasm in SAH Through CSF Treatment
The pathophysiological mechanisms of aneurysmal subarachnoid haemorrhage (aSAH) involve early brain injury (EBI) and delayed cerebral ischemia (DCI).
- Conditions
- Subarachnoid Hemorrhage, Subarachnoid Hemorrhage, Aneurysmal, Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- PREVAIL (NCT04490161)
- Testing
- intravenous reinstallation of cerebrospinal fluid
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University Innsbruck
Subarachnoid Hemorrhage, Aneurysmal, Emergency Medical Services
A Registry Study for Emergency Medical Service of Aneurysmal Subarachnoid Hemorrhage in China
This is a staged registry study of early treatment strategy management of acute aneurysmal subarachnoid hemorrhage(aSAH) among different economic development levels areas in China.
- Trial name
- CIAP-5 (NCT03115905)
- Where
- 2 sites in China
- Volunteers
- 6,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Cerebral Vasospasm
Safety Study of Nicardipine to Treat Cerebral Vasospasm
The purpose of this study is to determine if intrathecal nicardipine is safe for the treatment of cerebral vasospasm.
- Trial name
- NCT01810302
- Testing
- Nicardipine hydrochloride, Preservative-free normal saline
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Subarachnoid Hemorrhage, Cerebral Vasospasm
Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage
This study will evaluate the hypothesis that the administration of intraventricular tPA reduces the rates of cerebral vasospasm and ventriculoperitoneal shunt-dependent hydrocephalus in patients with aneurysmal subarachnoid…
- Conditions
- Subarachnoid Hemorrhage, Cerebral Vasospasm, Cerebral Aneurysm, Hydrocephalus
- Trial name
- NCT01878136
- Testing
- Tissue Plasminogen Activator
- Where
- United States
- Sponsor
- Rush University Medical Center
Aneurysmal Subarachnoid Hemorrhage
Human Albumin for Clinical Outcome in Aneurysmal Subarachnoid Hemorrhages
Aneurysmal subarachnoid hemorrhage (aSAH) is a dreadful acute neurological condition with overwhelmingly high rate of associated morbidities and mortality.
- Trial name
- HASH (NCT06548477)
- Testing
- Human albumin
- Where
- Qatar
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Subarachnoid Hemorrhage, Aneurysmal
Artificial Intelligence in Subarachnoid Hemorrhage
The overall aim of this study is to, with the help of computer/data scientist and machine learning processes, analyse collected heart rate variability data in order to evaluate whether specific patterns could be found in patients…
- Trial name
- AISAH (NCT04415736)
- Testing
- No intervention, observational study
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Göteborg University
Subarachnoid Hemorrhage, Aneurysmal
Induced Suppression of Platelets Activity in Aneurysmal SAH Management (iSPASM)
This is a phase 1/2a, randomized, double blind, single-center study comparing standard care alone to standard care with Aggrastat in patients diagnosed with aneurysmal subarachnoid hemorrhage.
- Trial name
- NCT03691727
- Testing
- tirofiban hydrochloride (AGGRASTAT®), MRI, Neurological Exam
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- David Hasan
Aneurysmal Subarachnoid Hemorrhage
Application of Magnesium-rich Artificial Cerebrospinal Fluid in Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) is a common type of acute hemorrhagic stroke. One of its complications, cerebral vasospasm (CVS), is the main cause of death and disability, with an incidence of up to 30%-90%.
- Trial name
- NCT04358445
- Testing
- Magnesium-Rich Artificial Cerebrospinal Fluid
- Where
- China
- Volunteers
- 70 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Aneurysmal Subarachnoid Hemorrhage
Astragalus Membranaceus on Aneurysmal Subarachnoid Hemorrhage
This research is trying to see if AM can enhance the clinical prognosis for spontaneous aneurysm ruptured subarachnoid hemorrhage patients.
- Trial name
- AMASH (NCT03271697)
- Testing
- Astragalus Membranaceus
- Volunteers
- 120 people
- Sponsor
- China Medical University Hospital
Aneurysmal Subarachnoid Hemorrhage
Dome-Only Aneurysm Coiling in Severe Aneurysmal Subarachnoid Hemorrhage
The DOME study is a clinical trial exploring a new treatment approach for patients who suffered a severe brain bleed due to an aneurysm.
- Trial name
- DOME (NCT07250958)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Louisville
Subarachnoid Hemorrhage of Aneurysmal Cause
Observational Study on Mortality and Outcome of Patients Hospitalized for Subarachnoid Hemorrhage of Aneurysmal Origin in Martinique Between 2013 and 2021
The aim of our study is to analyze mortality and sequelae of subarachnoid hemorrhage of aneurysmal origin in hospitalized patients in Martinique. Predictive factors of poor prognosis will also be analyzed.
- Trial name
- HSA Rankin (NCT06525012)
- Testing
- Usual patient care for patients hospitalized for subarachnoid hemorrhage of aneurysmal origin
- Where
- Martinique
- Volunteers
- 122 people
- Sponsor
- University Hospital Center of Martinique
Subarachnoid Hemorrhage, Aneurysmal, Cognitive Dysfunction
Gamma Entrainment Stimulation for Cognitive Dysfunction After aSAH
The goal of this clinical trial is to Explore and verify whether 40Hz audio and binaural beat 40Hz audio can improve the postoperative cognitive dysfunction seen in patients with aneurysmal subarachnoid hemorrhage.
- Trial name
- GES-aSAH (NCT06346015)
- Testing
- Gamma Entrainment Stimulation
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Subarachnoid Hemorrhage, Aneurysmal
Evaluation of Neuroinflamation of SAH
The investigators are planning that can these markers be used a predictive marker at SAH and for this aim we will study both patiens' blood sample and their CT image.
- Trial name
- BAP (NCT03822260)
- Testing
- Bezmialem VAkif Unv. Ethical board
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University