Clinical trials: Aneurysm Aortic, open to volunteers
Heart Failure, Liver Fibrosis
Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
Magnetic resonance elastography is a novel non-invasive MRI technique to obtain stiffness of soft tissues such as liver, heart, kidneys, etc.
- Conditions
- Heart Failure, Liver Fibrosis, Cardiac Transplant Rejection, Aortic Aneurysms
- Trial name
- MRE (NCT01757730)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Arunark Kolipaka
Abdominal Aortic Aneurysm
Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms
The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA).
- Trial name
- AAA-MRE (NCT02387255)
- Testing
- Resoundant Driver System
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Abdominal Aortic Aneurysm
Screening for Abdominal Aortic Aneurysms in the General Practice by Ultraportable Ultrasound
Abdominal aortic aneurysm (AAA) is a localized dilatation of a segment of the aorta artery in its abdominal portion. It affects 1.7% of men aged 65 years and older.
- Trial name
- DACEP (NCT05617326)
- Testing
- AAA screening by a GP, AAA screening by a radiologist
- Where
- 6 sites in France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Descending Aortic Aneurysm, Ultrasound
TransThoracic Ultrasound for Descending Aortic Aneurysms
The goal of this observational study is to assess the applicability of non-invasive ultrasound in aneurysms of the descending thoracic aorta.
- Conditions
- Descending Aortic Aneurysm, Ultrasound, Accuracy, Feasibility
- Trial name
- THORUS (NCT07752654)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Rare Diseases, Thoracic Aortic Aneurysm (TAA)
Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aortic Diseases
The aim of the present study is to characterise the phenotype of fibroblasts and to classify different mechanisms involved in the onset and progression of TAAD in syndromic and non-syndromic subjects in order to evaluate…
- Conditions
- Rare Diseases, Thoracic Aortic Aneurysm (TAA), Marfan Syndrome
- Trial name
- FIBRA (NCT06786754)
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Abdominal Aortic Aneurysm
Molecular Imaging of the Underlying Mechanism of Vessel Wall Inflammation Using Positron Emission Tomography (PET/CT)
This research study is being conducted to test how an imaging drug called 64Cu-DOTA-ECL1i can be used to image an abdominal aortic aneurysm.
- Trial name
- NCT07548099
- Testing
- 64Cu-DOTA-ECL1i
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Aortic Valve Disease, Aortic Aneurysm
Aortopathy Relationship To Imagery and Kinocardiography Features (ARTIK)
Kinocardiography (KCG) is a portable measurement technique developed to estimate cardiac mechanical performance by studying the vibrations produced by myocardial contraction during each heartbeat and transmitted to the body…
- Trial name
- ARTIK (NCT06286358)
- Testing
- Kinocardiography
- Where
- Belgium
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Aortic Aneurysm, Aortic Dissection
Cardiovascular Health Improvement Project
The goal of this project is to establish a biobank of clinical information, DNA, plasma, and aortic tissue samples from patients with cardiovascular disease as well as healthy controls.
- Conditions
- Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure
- Trial name
- CHIP (NCT02306200)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Aortic Aneurysm, Aortic Aneurysm Abdominal
AI-CARE: Artificial Intelligence for Cardiovascular Analysis and Risk Evaluation
This study will test how well an artificial intelligence (AI) software called Aorta AIM measures the size of the aorta (the body's main blood vessel) from CT scans.
- Conditions
- Aortic Aneurysm, Aortic Aneurysm Abdominal, Aortic Aneurysm and Dissection, Aortic Aneurysm, Thoracoabdominal
- Trial name
- AI-CARE (NCT07438327)
- Testing
- Aorta AIM Automated Measurement, Expert Radiologist Manual Measurement
- Where
- 3 sites in United States, Brazil
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Aiatella Oy
Aorta Disease, Aorta Aneurysm
Assess Abdominal Aortic Diameter in Females
Female subjects aged 50 years or older will be enrolled. Biometric data (measurements) of the aorta and iliac vessels, demographic data, pathophysiological history, and data relating to menarche, pregnancy/infertility, and…
- Trial name
- AFRODITE (NCT07487961)
- Where
- Italy
- Volunteers
- 652 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Abdominal Aortic Aneurysm
PET Imaging of MMP Activation in AAA: Clinical Component
A first-in-human evaluation of [64Cu]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale)…
- Trial name
- PET AAA (NCT07473102)
- Testing
- Cu-64-RYM2, PET imaging using Cu-64
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Aortic Aneurysm, Aortic Aneurysm and Dissection
Multidisciplinary Analysis by Morphological and Mechanical Evaluation of the Aortic Wall in Patients Undergoing Cardiac Surgery.
Surgical indication in patients suffering from Ascending aorta aneurysm is currently based mainly on the maximum diameter of the aortic dilatation and on the yearly growth rate.
- Trial name
- NCT07422129
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Aortic Aneurysm, Aortic Dissection
Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease
The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenotype associated with these…
- Conditions
- Aortic Aneurysm, Aortic Dissection, Aortic Diseases
- Trial name
- MAC:H-TAD (NCT04005976)
- Where
- 20 sites in United States, Australia and 4 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Aortic Aneurysm
Exercise Physiology in Patients With Aortic Aneurysm and Its Correlation With Mechanical Properties of Aortic Tissue
Aortic aneurysm patients benefit from exercise yet patients and physicians do not know a safe level. Cardiac MRI (CMR) is the most comprehensive imaging modality for phenotypic evaluation of patients with cardiac disease but it…
- Trial name
- NCT06789809
- Testing
- Exercise MRI
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Renal Cell Carcinoma (Kidney Cancer), Kidney Cancers
Targeted Abdominal CT in Conjunction With Lung Cancer Screening
Early detection through screening can improve cancer survival by identifying it when it's most treatable. The NHS now offers Lung Cancer Screening (LCS) assessments to people aged 55-74 who have ever smoked.
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Kidney Cancers, AAA - Abdominal Aortic Aneurysm, Renal Stones
- Trial name
- TACTICAL1 (NCT07171190)
- Testing
- Lung Cancer Screening Invitation Intervention, Abdominal scan intervention
- Where
- United Kingdom
- Volunteers
- 6,272 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Incisional Hernia, Aortic Aneurysm
Prophylactic Mesh Reinforcement After Open Aortic Aneurysm Repair
The goal of this retrospective observational study is to evaluate whether prophylactic mesh reinforcement during abdominal wall closure can prevent incisional hernias (IH) in patients undergoing open abdominal aortic aneurysm…
- Trial name
- NCT06762561
- Testing
- Prophylactic retromuscular mesh reinforcement
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hôpital Fribourgeois
Breast Cancer, Bowel Cancer
EQUITA - A Feasibility Trial of a Faith-placed Intervention to Increase Screening Uptake in Black Adults
The goal of this randomised feasibility trial is to examine feasibility and acceptability of a co-produced and faith-placed intervention to increase uptake of breast, cervical, bowel, and abdominal aortic aneurysm (AAA) screening…
- Conditions
- Breast Cancer, Bowel Cancer, Cervical Cancer, Abdominal Aortic Aneurysm
- Trial name
- EQUITA (NCT06981182)
- Testing
- Faith-placed intervention to promote breast, cervical, bowel, and AAA screening uptake in Black communities.
- Where
- 3 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sunderland
Abdominal Aortic Aneurysm, Erectile Dysfunction
Screening for Aortic Aneurysms in Inland Norway
The number of AAA-surgeries performed per capita is 3-4 times higher in Innlandet county, as compared to Oslo. The last three years the annual incidence of AAA requiring treatment has been 21.5 / 100 000 inhabitants in Innlandet…
- Conditions
- Abdominal Aortic Aneurysm, Erectile Dysfunction, Quality of Life
- Trial name
- NOR-AORTA (NCT06403423)
- Where
- Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sykehuset Innlandet HF
Aortic Aneurysm, Abdominal, Renal Insufficiency
Renal Function After Stentgraft Treatment Of Abdominal Aortic Aneurysm
This randomized controlled trial aim to determine the impact on renal function after treatment for infrarenal abdominal aortic aneurysm (AAA) with stentgrafts either with active supra- or infrarenal fixation.
- Conditions
- Aortic Aneurysm, Abdominal, Renal Insufficiency, Stent-Graft Thrombosis
- Trial name
- RENOFIX (NCT04754659)
- Testing
- Stentgraft
- Where
- Sweden
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region