Clinical trials: Anesthesia Outcomes
Cesarean Section Complications, Postpartum Hemorrhage
Perioperative Outcomes of Postpartum Hemorrhage in Patients Undergoing Cesarean Delivery
Postpartum haemorrhage is the common cause of maternal death worldwide. The primary purpose of this study is to identify the maternal outcomes after PPH.
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Anesthesia Complication, Blood Transfusion Complication
- Trial name
- NCT04833556
- Where
- Thailand
- Volunteers
- 649 people
- Sponsor
- Mahidol University
Brain Tumor
Influences of Propofol and Sevoflurane Anesthesia in Brain Tumor
In the preoperative waiting area, the patients are randomly assigned and divided into two groups according to the allocation sequence table (corresponding to 1:1 randomization) generated by the computer.
- Trial name
- anesthetics (NCT05141877)
- Testing
- Propofol, Sevoflurane
- Where
- Taiwan
- Volunteers
- 706 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Colorectal Neoplasms, Anesthesia
Effects of Anesthetic Techniques on Time to Start of Adjuvant Chemotherapy Following Surgery for Colorectal Cancer
Colorectal cancer (CRC) is the third most common cancer in the world with a high postoperative mortality (2 - 6%) as well as a low 5-year survival (40%).
- Conditions
- Colorectal Neoplasms, Anesthesia, Drug Therapy, Surgery
- Trial name
- ENCORE (NCT04493905)
- Where
- Sweden
- Volunteers
- 5,500 people
- Sponsor
- European Society of Anaesthesiology
Postoperative Delirium, Postoperative Stroke
Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery
This international, multicentre prospective cohort study will assess whether perioperative duration and magnitude of mean arterial pressure (MAP) outside of an individual's cerebral autoregulation (CA) limits using near-infrared…
- Conditions
- Postoperative Delirium, Postoperative Stroke, Postoperative Cognitive Dysfunction
- Trial name
- PRECISION (NCT05595954)
- Testing
- Preoperative data collection, Intraoperative NIRS, Intraoperative TCD
- Where
- 4 sites in Switzerland, United Kingdom
- Volunteers
- 500 people
- Sponsor
- University Hospital, Basel, Switzerland
Pericardial Effusion, Inflammatory Response After Surgery
Anesthesia Management, Inflammatory Response and Recovery After Non-intubated VATS Pericardial Window
Non-intubated video-assisted thoracoscopic surgery (NIVATS) is performed under spontaneous ventilation and avoids tracheal intubation and one-lung mechanical ventilation.
- Conditions
- Pericardial Effusion, Inflammatory Response After Surgery, Postoperative Complications, Procedural Sedation and Analgesia
- Trial name
- RNIVATS (NCT07800767)
- Testing
- Systemic opioid-based analgesia during NIVATS, Thoracic regional analgesia during NIVATS
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Koşuyolu Kartal Heart Training and Research Hospital
Gallbladder Disease
Effect IV Ibuprofen and Inflammatory Responses
This study is being done because the investigators wish to study ways to improve recovery after surgery. Injury, including surgical injury, causes inflammation.
- Trial name
- NCT01938040
- Testing
- ibuprofen
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Kidney Stone, Anesthesia
Anesthesia Type on Percutaneous Nephrolithotomy in Aging Male
The aim of this study is to compare the anesthesia methods in percutaneous nephrolithotomy in terms of safety and effectiveness in elderly men.
- Trial name
- NCT05431049
- Testing
- Percutaneous nephrolithotomy surgery (PNL)
- Where
- Turkey (Türkiye)
- Volunteers
- 184 people
- Sponsor
- Sedat Önen
Parkinson's Disease
DBS Under General Anesthesia: Comparison To The Standard Technique
There is a growing trend in functional neurosurgery toward direct anatomical targeting for deep brain stimulation (DBS). This study describes a method and reports the initial experience placing DBS electrodes under general…
- Trial name
- NCT01997398
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Simulation
Effect of an Observer Tool on Learning Outcomes During High Fidelity Simulation
The increasing use of high-fidelity simulation is limited by the imbalance between the growing number of students and the human resources available in such a way that all residents cannot play a role during scenarios.
- Trial name
- NCT03356717
- Testing
- educational intervention with observer tool, educational intervention
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Université Paris-Sud
Sugammadex, Pregnant, Anesthesia
Sugammadex Administration in Pregnancy
In this study, the investigators aimed to evaluate the maternal and fetal effect of sugammadex in pregnant patients undergoing a non-obstetric surgery.
- Trial name
- NCT05708469
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Sakarya University
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction
Tau/P-Tau and Neurocognitive Outcomes in Children
The proposed studies are aimed to measure Tau and P-Tau levels in pre- and postoperative blood, urine, feces and saliva, as well as to assess pre- and postoperative neurocognitive function in children (3 to 5 years old) who will…
- Conditions
- General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
- Trial name
- NCT03511729
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Anesthesia, Postoperative Complications
South African Paediatric Surgical Outcomes Study (SAPSOS)
There are few data of paediatric peri-operative morbidity and mortality in South Africa. There is little information on the burden or profile of surgical disease in the paediatric population, the level of anaesthesia or surgical…
- Conditions
- Anesthesia, Postoperative Complications, Child Mortality, Hospital Mortality
- Trial name
- SAPSOS (NCT03367832)
- Where
- South Africa
- Volunteers
- 2,025 people
- Sponsor
- University of KwaZulu
Perioperative/Postoperative Complications, Morbidity, Multiple
Machine Learning Modeling of Intraoperative Hemodynamic Predictors of Postoperative Outcomes
With population aging and limited resources, strategies to improve outcomes after surgery are ever more important. There is a limited understanding of what ranges of hemodynamic variables under anesthesia are associated with…
- Conditions
- Perioperative/Postoperative Complications, Morbidity, Multiple, Surgery, Anesthesia
- Trial name
- NCT04014010
- Testing
- Blood pressure, Heart rate, Use of hemodynamic medications (i.e. special medications for blood pressure)
- Volunteers
- 35,000 people
- Sponsor
- Janny Xue Chen Ke
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Mortality, Surgical Complication
Clinical Outcomes in Adult Patients Undergoing Laparoscopic Surgery Under Neuraxial Anesthesia
The goal of this observational study is to learn about postoperative mortality and postoperative length of stay outcomes after abdominal laparoscopic major surgery.
- Conditions
- Mortality, Surgical Complication, Neurological Complication, Respiratory Complication
- Trial name
- NEURAX (NCT06360666)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Asst Melegnano e Martesana
Children, Hernia, Inguinal
Comparing Inhalation and Total Intravenous Anesthesia Methods
This study compares the effects of anesthesia using target-controlled infusion (TCI) and inhalation methods on pediatric patients undergoing inguinal hernia repair.
- Trial name
- TIVA-IHA (NCT06467279)
- Testing
- Target Controlled İnfusion, Inhalation anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
General Anesthesia, Laparotomy
Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy
The effects of anesthesia and surgery can lead to stress responses that result in hormonal and metabolic changes in the body. The immune system and the nervous system communicate both ways, and it was found that nociception and…
- Conditions
- General Anesthesia, Laparotomy, Inflammation
- Trial name
- PRO-Ketamine (NCT04462094)
- Testing
- Ketamine 0.3 mg/kg at end-of-surgery, Ketamine 0.3 mg/kg at anesthesia induction
- Where
- Indonesia
- Volunteers
- 68 people
- Sponsor
- Udayana University
Outcome
Norepinephrine and Phenylephrine for Spinal Anesthesia-induced Hypotension.
This study aims to explore the effects of different application modes (prophylactic and rescue strategy) of norepinephrine and norepinephrine on neonate umbilical artery pH undergoing cesarean section.
- Trial name
- NCT06508359
- Testing
- Norepinephrine, Phenylephrine
- Where
- China
- Volunteers
- 700 people
- Sponsor
- General Hospital of Ningxia Medical University
Acute Kidney Injury, Surgery Complications
Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial
This investigator-initiated, pragmatic trial evaluates whether displaying a machine learning (ML)- derived perioperative AKI risk score-alone or paired with an interruptive Best/Our Practice Advisory (BPA/OPA)-improves…
- Conditions
- Acute Kidney Injury, Surgery Complications, Anesthesia
- Trial name
- ML-AKI (NCT07604662)
- Testing
- EHR-Embedded AKI Risk Score, EHR-Embedded AKI Risk Score with Best Practice Advisory
- Where
- United States
- Volunteers
- 25,518 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain Syndrome, Analgesia
Erector Spinae Plane Block Versus Paravertebral Block for Analgesia After Cardiac Surgery (PEPS)
The purpose of this randomized double-blind study is to compare the analgesic efficacy of the bilateral Erector Spinae Plane (ESP) block versus the bilateral Thoracic Paravertebral block (TPVB), by ultrasound-guided single…
- Conditions
- Pain Syndrome, Analgesia, Anesthesia, Local
- Trial name
- PEPS (NCT04546113)
- Testing
- Ultrasound-guided Bilateral Paravertebral Block performed with a 20 ml injection of Ropivacaine 3,75 mg/ml/side, Ultrasound-guided Bilateral Erector Spinae plane Block performed with a 20 ml injection ropivacaine 3,75 mg/ml/side
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Institut Mutualiste Montsouris