Clinical trials: Anesthesia Morbidity
Stroke, Endovascular Repair
GA vs. CS for Endovascular Stroke Therapy
After a stroke caused by a blockage (clot) in a blood vessel in the brain, patients may have the clot removed by threading a catheter from the groin up to the affected area of the brain.
- Conditions
- Stroke, Endovascular Repair, Anesthesia
- Trial name
- NCT03247998
- Testing
- General Anesthesia, Conscious Sedation with Remifentanil
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Rupture of Anterior Cruciate Ligament, Infiltration
Local Infiltration Analgesia vs Adductor Canal Block for Analgesia After Anterior Cruciate Ligament Reconstruction
Early rehabilitation after anterior cruciate ligament reconstruction is of paramount importance and requires optimal pain control based on a multimodal concept, including injection of local anaesthetics.
- Conditions
- Rupture of Anterior Cruciate Ligament, Infiltration, Regional Anesthesia Morbidity
- Trial name
- NCT02524652
- Testing
- Ropivacaine 0.5% 20 mLs
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Anesthesia, Bariatric Surgery Candidate
EOI Block Versus ESP Block in Laparoscopic Bariatric Surgery
This study aims to compare a single shot of bilateral ultrasound-guided EOI block and ESPB in terms of intraoperative opioid consumption, postoperative pain control in the first 24 hours, and the need for rescue analgesics.
- Conditions
- Anesthesia, Bariatric Surgery Candidate, Regional Anesthesia Morbidity
- Trial name
- NCT06168903
- Testing
- Ultrasound guided EOI block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Anesthesia, Perinatal Morbidity
General Anesthesia for Cesarean Section, Maternal and Perinatal Outcomes
To evaluate the maternal and perinatal outcomes that occur in obstetric patients undergoing cesarean section surgery under general anesthesia at the Fray Antonio Alcalde Civil Hospital of Guadalajara.
- Conditions
- Anesthesia, Perinatal Morbidity, Maternal-Fetal Relations
- Trial name
- NCT06160583
- Where
- Mexico
- Volunteers
- 5,000 people
- Sponsor
- Hospital Civil de Guadalajara
Regional Anesthesia Morbidity
M-TAPA vs Intraperitoneal Bupivacain vs Intraperitoneal Bupivacain +Dexmedetomidin
Laparoscopic cholecystectomy is a common abdominal surgery in Western countries, favored for its minimal invasiveness, leading to less pain, smaller scars, and quicker recovery.
- Trial name
- NCT06482229
- Testing
- application for postoperative analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Sivas State Hospital
Regional Anesthesia Morbidity, Arthropathy of Hip
Comparison of PENG Associated with LFCN Block Versus FICB for Multimodal Analgesic Management in THA
Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation. Fascia iliaca compartment block (FIC) has been recommended since it offers the best pain control with low…
- Conditions
- Regional Anesthesia Morbidity, Arthropathy of Hip, Hip Arthropathy, Post Operative Pain
- Trial name
- NCT06147401
- Testing
- PENG plus LFCN block, FIC Block
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- Ospedale Edoardo Bassini
Regional Anesthesia Morbidity
Does Use of Ultrasound Reduce the Rate of Sham Caudal Block in Children
Caudal blocks are one of the most commonly performed regional anesthetics in children and are performed daily for a host of infra-umbilical surgical procedures.
- Trial name
- NCT03283865
- Testing
- Ultrasound guidance for caudal block
- Where
- United States
- Sponsor
- Baylor College of Medicine
Regional Anesthesia Morbidity, Pain, Postoperative
Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery
Minimally Invasive Thoracic Surgery (MITS) is a surgical method used to perform lung surgery through small incisions between the ribs and includes both Video-Assisted Thoracic Surgery (VATS) and Robotic assisted Thoracic Surgery…
- Conditions
- Regional Anesthesia Morbidity, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04729712
- Testing
- Anaesthesiologist-administered ultrasound guided Erector Spinae block with catheter insertion, Surgeon-administered video-assisted Paravertebral block with catheter insertion
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Frail Elderly Syndrome
The Importance of Anesthesia Method in Fragile Patients
The aim of this study is to comparatively evaluate the effects of different anaesthesia methods (spinal anaesthesia and general anaesthesia) administered to frail elderly patients scheduled for transurethral surgery (e.g.
- Trial name
- NCT07191769
- Testing
- general anaesthesia, regional anaesthesia
- Volunteers
- 180 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Cesarean Section Complications, Regional Anesthesia Morbidity
Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Jugular vein collapsibility index and shock indices (Shock index, Modified Shock Index, Diastolic Shock Index) may be useful in estimating post spinal hypotension in cesarean section operations.
- Conditions
- Cesarean Section Complications, Regional Anesthesia Morbidity, Hemodynamic Instability, Shock
- Trial name
- NCT05953129
- Testing
- Right Jugular Vein Collapsibility Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Postoperative Morbidity, Postoperative Mortality
Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study)
The primary purpose of the study is to evaluate whether the type of fluid (0.9% saline or 6% Hydroxyethyl starch 130/0.4) in the context of an individualized goal-directed fluid therapy is associated with a difference in…
- Trial name
- FLASH (NCT02502773)
- Testing
- Hydroxethyl starch
- Where
- France
- Volunteers
- 826 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anesthesia, Regional Anesthesia Morbidity
Pericapsular Nerve Group Block vs Interscalene Block for Shoulder Arthroscopy
This study aims to compare PENG block and LV-ISBP block in the incidence of phrenic nerve block, duration of postoperative analgesia, time to first analgesic request (VAS > 30 mm), pain scores, and side effects.
- Conditions
- Anesthesia, Regional Anesthesia Morbidity, Shoulder Pain, Arthroscopy
- Trial name
- NCT06208774
- Testing
- Ultrasound-guided PENG or ISBP block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Tracheal Intubation Morbidity
Videolaryngoscopy vs. Direct Laryngoscopy for Elective Airway Management in Pediatric Anesthesia
Videolaryngoscopy can lead to superior airway conditions and to the possible higher success compared to standard direct laryngoscopy.
- Trial name
- Videoscopy (NCT03747250)
- Testing
- Videolaryngoscopy, Direct laryngoscopy
- Where
- Czechia
- Volunteers
- 501 people
- Sponsor
- Brno University Hospital
Adult, Regional Anesthesia Morbidity
How Do We Ultrasound-Guided Popliteal Approach Sciatic Nerve Block?
The aim of this prospective, randomized, observer-blind study to compare subparaneural approach injection with interneural approach injection in popliteal sciatic nerve blocks.
- Conditions
- Adult, Regional Anesthesia Morbidity, Anesthesia Injection Site
- Trial name
- NCT06372691
- Testing
- Subparaneural Injection (Grup S), Block, Interneural Injection (Grup I), Block
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Airway Morbidity
Comparison of Ease of I-gel Insertion With Two Different Techniques in Adults
Study will evaluate the I-gel airway device standard insertion technique versus interventional (modified jaw thurst) insertion technique in adult patients.
- Trial name
- NCT04109898
- Testing
- Supraglottic airway device (I-gel) insertion
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Regional Anesthesia, Regional Anesthesia Morbidity
Impact of Communication Delays on Anesthesia Response to Medical Emergencies and Ultrasound-Guided Regional Anesthesia
Hypotheses The investigators hypothesize that a communication delay of 80 seconds compared to no delay will be associated with longer procedural times and decreased quality during brachial plexus block scanning.
- Conditions
- Regional Anesthesia, Regional Anesthesia Morbidity, Regional Anesthesia Success, Remote Consultation, Teleconsultation
- Trial name
- ICARUS (NCT07675863)
- Testing
- Real-time communication, Delayed communication
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Coronary Artery Disease
The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial
To investigate the safety of nitrous oxide (N2O) anaesthesia in patients with risk factors for coronary artery disease undergoing major surgery.
- Trial name
- NCT00430989
- Testing
- Nitrous Oxide, No Nitrous Oxide
- Where
- Australia
- Volunteers
- 7,112 people
- Sponsor
- Bayside Health
Bupivacaine Adverse Reaction, Regional Anesthesia Morbidity
Sequential and Mixture Injection of Opioids and Hyperbaric Bupivacaine
Neuraxial anesthesia, especially the subarachnoid block, is the preferred method for LSCS. The intrathecal spread of local anesthetic drugs is unpredictable.
- Conditions
- Bupivacaine Adverse Reaction, Regional Anesthesia Morbidity, Cesarean Section Complications
- Trial name
- NCT04403724
- Testing
- Bupivacaine-fentanyl-Morphine.
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Assiut University
Regional Anesthesia Morbidity
Serratus Anterior Plane Block and Costotransverse Block for Analgesia Following Modified Radical Mastectomy Surgeries
Adequate pain management following modified radical mastectomy (MRM) is crucial for early ambulation and patient satisfaction. Breast cancer is the most common malignancy in females, with an increasing incidence in recent years.
- Trial name
- NCT06260397
- Testing
- serratus anterior plane block, costotransverse block, patient controlled analgesia
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain, Regional Anesthesia Morbidity
Rhomboid Intercostal and Subserratus Plane Block
This clinical trial will be conducted at Tanta University Hospitals, General Surgery Hospitals on female patients undergoing radical mastectomy . All the patients will receive general anesthesia.
- Trial name
- NCT04085263
- Testing
- Control group, Rhomboid intercostal and subserratus plane block group
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- Tanta University