Clinical trials: Anesthesia Morbidity
Morbidity, Mortality
Outcome of Patients After Total Knee Replacement: A Comparison of Femoral Nerve Block and Epidural Anesthesia
Total knee replacement is very common in Germany. After surgery patients have severe pain in the knee; initiation of the physiotherapy, however, is important in the first three days after surgery.
- Conditions
- Morbidity, Mortality, Complications, Function
- Trial name
- NCT01631799
- Testing
- Femoral catheter, Epidural catheter
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University of Rostock
Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block
Comparison of the Effects of Interscalene Block and Superior Trunk Block on Pulmonary Functions
The interscalene block (ISB) is one of the peripheral nerve blocks providing surgical anesthesia and postoperative analgesia in shoulder arthroscopy, eliminating the need for general anesthesia.
- Conditions
- Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block, Phrenic Nerve Paralysis
- Trial name
- NCT06703281
- Testing
- Interscalene Nerve Block, Superior trunk block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Gazi University
Postoperative Complications
Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity
In General anesthesia, two main ways of pain control are used intra-operatively, one is opioids, the other is epidural. Many colleges prefer using epidural analgesia because it is potent and more effective , and also the benefits…
- Trial name
- NCT01884298
- Where
- China
- Sponsor
- Peking University First Hospital
Regional Anesthesia Morbidity
Effect of Modified 45-degree Head-up Tilt Position in Cesarean Operation to the Success of Spinal Anesthesia
The success of the application of spinal block in 3 different application as the sitting position, side decubitus position and 45 degrees head upside side decubitus position will be evaluated.
- Trial name
- cesarean (NCT03740399)
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Trakya University
Carotid Atherosclerosis, Regional Anesthesia Morbidity
Anterior Ultrasound-guided Cervical Plexus Block for Carotid Endarterectomy
The aim of this study is to describe technique, efficiency, safety and satisfaction of ultrasound guided intermediate cervical plexus block for carotid endarterectomy.
- Trial name
- NCT01640613
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Hôpital Edouard Herriot
Anesthesia Morbidity
HIFLO ENDO-High Flow Nasal Cannula in GI Endoscopy
Millions of patients undergo upper GI endoscopy in the United States each year. A large number of these patients have anesthesia to assist with their comfort during the procedure.
- Trial name
- NCT03028688
- Testing
- High flow nasal cannula oxygen
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Opioid Use, Anesthesia Morbidity
Paragastric Autonomic Neural Blockade as Part of Combined Anesthesia.
To evaluate the effect of early autonomic blockade on the consumption of remifentanil and halogenated anesthesia in the intraoperative period during laparoscopic sleeve gastrectomy.
- Trial name
- NCT05668845
- Testing
- PG-ANB performed at the outset of LSG, PG-ANB performed at the end of the LSG
- Where
- Colombia
- Volunteers
- 79 people
- Sponsor
- Universidad Simón Bolívar
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
Mastectomy; Lymphedema, Chronic Pain
Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy
The goal of this clinical trial is to learn if the erector spinae block can reduce the incidence of chronic pain compared to the paravertebral block in adult patients undergoing total mastectomy.
- Conditions
- Mastectomy; Lymphedema, Chronic Pain, Regional Anesthesia Morbidity, Opioid Use
- Trial name
- NCT07561411
- Testing
- Paravertebral block, Erector Spinae block
- Where
- Lebanon
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Foot Deformities, Regional Anesthesia Morbidity
Impact of Virtual Reality Hypno-sedation on Functional Recovery and Anxiety in Foot Surgery With Regional Anesthesia
This prospective study aims to evaluate whether the implementation of a virtual reality hypnosedation (VRH)protocol reduces preoperative anxiety and increases patient comfort before, during, and after outpatient foot surgery.
- Conditions
- Foot Deformities, Regional Anesthesia Morbidity, Valgus; Hallux, Analgesia
- Trial name
- NCT05558449
- Testing
- Hypnosedation, Midazolam injection, Virtual reality
- Where
- Belgium
- Volunteers
- 57 people
- Sponsor
- University of Liege
Anesthesia, Regional Anesthesia Morbidity
Motor Sparing Supraclavicular Block
This study aims to compare MS-SCBPB and SCBPB in the duration of postoperative analgesia, time to first analgesic request (VAS ≥40 mm), pain scores, motor power, and side effects.
- Trial name
- NCT06074471
- Testing
- ultrasound guided supraclavicular brachial plexus block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Post Operative Pain, Regional Anesthesia Morbidity
Does ESP Block Reduce Pain and Opiates Consumption After Surgery
The patients will be randomly assigned to standard therapy or standard therapy+ESP nerve block. After surgery pain level and narcotic consumption will be measured, and vital signs and side effects will bo monitored for up to 72…
- Conditions
- Post Operative Pain, Regional Anesthesia Morbidity, Opioid-Related Disorders, Chronic Pain
- Trial name
- NCT05512897
- Testing
- erector spinea plane block
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michael Dubilet MD
All Conditions Requiring Non-cardiac Surgery
Impact of Training on the Use of Software and Digital Monitoring Tools During General Anesthesia for Intermediate/Major-risk Surgery on Morbidity and Mortality at 28 Days
Tools such as surgical plethysmographic index, state entropy, train-of-four monitors exist to optimize the conduct of general anesthesia in intermediate and major risk surgery as defined by the 2022 European Society of Cardiology…
- Trial name
- AoA QUALITY (NCT06111248)
- Testing
- Training
- Where
- France
- Volunteers
- 1,028 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Anesthesia Morbidity, Sore Throat
Postoperative Sore Throat in the Pediatric Population.
Endotracheal tubes (ETT) and laryngeal mask airways (LMA) are devices used to help breathing whilst patients are asleep for surgery.
- Trial name
- POST (NCT03389776)
- Testing
- Anesthesia
- Where
- United Kingdom
- Volunteers
- 197 people
- Sponsor
- Istituto Giannina Gaslini
Coronary Artery Disease
The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial
To investigate the safety of nitrous oxide (N2O) anaesthesia in patients with risk factors for coronary artery disease undergoing major surgery.
- Trial name
- NCT00430989
- Testing
- Nitrous Oxide, No Nitrous Oxide
- Where
- Australia
- Volunteers
- 7,112 people
- Sponsor
- Bayside Health
Postoperative Pain, Postoperative Complications
Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
The aim of this prospective randomized study was to compare the effectiveness of subcostal transversus abdominis plane block or rectus sheath block applied in addition to posterior transversus abdominis plane block for…
- Conditions
- Postoperative Pain, Postoperative Complications, Analgesia, Regional Anesthesia Morbidity
- Trial name
- NCT06342076
- Testing
- Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block, Patients undergoing rectus sheat block and posterior transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Perioperative/Postoperative Complications, Morbidity, Multiple
Machine Learning Modeling of Intraoperative Hemodynamic Predictors of Postoperative Outcomes
With population aging and limited resources, strategies to improve outcomes after surgery are ever more important. There is a limited understanding of what ranges of hemodynamic variables under anesthesia are associated with…
- Conditions
- Perioperative/Postoperative Complications, Morbidity, Multiple, Surgery, Anesthesia
- Trial name
- NCT04014010
- Testing
- Blood pressure, Heart rate, Use of hemodynamic medications (i.e. special medications for blood pressure)
- Volunteers
- 35,000 people
- Sponsor
- Janny Xue Chen Ke
Anesthesia Morbidity, Anesthesia; Adverse Effect
Comparison of CLSB With Sedation Versus General Endotracheal Anesthesia on Postoperative Outcomes in Elderly Patients Undergoing Hip Fracture Surgery
Hip fracture is a global public health problem. The postoperative mortality and disability rate of hip fracture is high, and early surgery is still the most effective treatment method, but these patients are often associated with…
- Trial name
- NCT03318133
- Testing
- anesthesia
- Where
- China
- Volunteers
- 1,086 people
- Sponsor
- Shanghai 6th People's Hospital
Pregnancy Complications, Cesarean Section Complications
A Quality Improvement Project - Peripartum Operating Room Leveling System
Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach.
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Morbidity;Perinatal
- Trial name
- NCT03552419
- Volunteers
- 1,380 people
- Sponsor
- Johns Hopkins University
Hypoxia, Endoscopy
Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
This study is a randomized controlled trial comparing oxygen delivery by nasal mask with continuous positive airway pressure versus standard care (nasal cannula or standard facemask) during propofol-based sedation for…
- Conditions
- Hypoxia, Endoscopy, Anesthesia Morbidity
- Trial name
- NCT03369197
- Testing
- Nasal Mask, Control: Nasal Cannula
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University