Clinical trials: Anesthesia,General
Mechanical Ventilation, Surgeries Undergoing General Anesthesia
Preoperative Characteristics and Outcomes of Neonates Undergoing Surgical Procedures in the NICU
This retrospective observational study evaluates neonates who underwent surgical procedures during admission to a neonatal intensive care unit (NICU).
- Trial name
- NeoSurg-Resp (NCT07793812)
- Testing
- Surgical Procedures
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Ayberk Ozkavakli
Laryngeal Masks
Comparative Evaluation of Ambu AuraGain Laryngeal Mask and Proseal Laryngeal Mask Airway
Comparison of two different supraglottic airway devices i.e., the ProSeal Laryngeal Mask Airway (PLMA) and Ambu AuraGain, a third generation laryngeal mask Airway.
- Trial name
- NCT03139292
- Testing
- ProSeal Laryngeal Mask Airway, AmbuAuraGain Laryngeal Mask Airway
- Where
- India
- Volunteers
- 160 people
- Sponsor
- Tata Main Hospital
Laryngeal Disease, Pharyngeal Diseases
Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
The purpose of this study is to compare the effects of remimazolam and propofol on postoperative recovery time, complications, and safety in patients undergoing ambulatory upper airway surgery under general anesthesia.
- Conditions
- Laryngeal Disease, Pharyngeal Diseases, Oral Cavity Disease, Nasal Disease
- Trial name
- NCT06507202
- Testing
- Remimazolam, Propofol
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- Chung-Ang University Gwangmyeong Hospital
Trauma, General Anaesthetic Drug Overdose
Modulation of General Anesthesia Using Entropy and Surgical Pleth Index
The critically ill polytrauma patient is one of the most complex cases with regard to the optimization of the intensive care, anesthesia, as well as postoperative management.
- Trial name
- ESPTR (NCT03095430)
- Testing
- Monitoring
- Volunteers
- 72 people
- Sponsor
- Romanian Society of Anesthesia and Intensive Care
Anesthesia,General, Neuromuscular Blockade
MONITORING NEUROMUSCULAR BLOCK IN PAEDIATRIC ANAESTHESIA
To date there is still little scientific evidence regarding neuromuscular block monitoring in pediatric anesthesia and indications for safe reversal.
- Conditions
- Anesthesia,General, Neuromuscular Blockade, Tracheal Intubation
- Trial name
- MOTOR (NCT06331611)
- Testing
- TOF monitoring
- Volunteers
- 200 people
- Sponsor
- Istituto Giannina Gaslini
Brain Neoplasms
Dexmedetomidine and Intelligence Development in Pediatric Patients Undergoing Craniotomy
The purpose of this randomized, double-blind and placebo-controlled pilot study is to investigate whether dexmedetomidine when used as an adjuvant to general anesthesia can decrease the harmful effects of anesthesia and surgery…
- Trial name
- NCT02810899
- Testing
- dexmedetomidine, normal saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University First Hospital
Visual Analogue Scale
Neural Therapy in Cesareans
In the management of pain after Caesarean section (C/S), opioid or nonsteroidal anti-inflammatory parenteral drugs are applied. These drugs are insufficient in some cases and may cause pain attacks during the day.
- Trial name
- NCT06999200
- Testing
- neural therapy
- Volunteers
- 156 people
- Sponsor
- Haseki Training and Research Hospital
Postoperative Pain, General Anesthesia
ANI-Guided Anesthetic Desflurane Consumption
General anesthesia requires precise titration of inhaled anesthetics like desflurane and opioids like remifentanil to balance sedation, analgesia, and hemodynamic stability.
- Conditions
- Postoperative Pain, General Anesthesia, Laparoscopic Cholecystectomy
- Trial name
- NCT06982209
- Testing
- Analgesia/Nociception Index (ANI)
- Where
- South Korea
- Volunteers
- 125 people
- Sponsor
- Wonkwang University Hospital
Anesthesia, ASA Physical Status I
Descriptive Observational Study of Patient-performed Pre-oxygenation
The aim of this research would be to determine the efficacy and effects of preoxygenation when performed by the patient (mask held by the patient). This is the concept of "self-preoxygenation".
- Conditions
- Anesthesia, ASA Physical Status I, ASA Physical Status II
- Trial name
- ApréOx (NCT06361693)
- Testing
- Auto-preoxygenation, APAIS scale, Visual analog anxiety scale (VAS-A)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lumbar Disc Disease
SPI-directed Analgesia for Lumbar Discectomy
The aim of this randomized trial is to assess the efficacy of analgesia for lumbar discectomy and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively.
- Trial name
- SPI (NCT02971540)
- Testing
- Metamizol, Tramadol, Bupivacaine
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Silesia
General Surgery With Endotracheal Intubation
The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation Under Propofol-remifentanil Anesthesia in Elderly Patients
To find out the effect site concentration of remifentanil for preventing QTc interval prolongation during intubation under propofol-remifentanil anesthesia in elderly patients
- Trial name
- NCT01720498
- Testing
- remifentanil
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Severance Hospital
Post-induction Hypotension (PIH), Hypertension (HTN)
Hemodynamic Effects of Lithotomy Position in Surgical Patients (PH-LITHO)
Anesthesia-induced hypotension is a common occurrence in elderly hypertensive patients and is closely associated with increased postoperative morbidity This study aims to investigate whether the lithotomy position, a…
- Conditions
- Post-induction Hypotension (PIH), Hypertension (HTN), Geriatric Anesthesia
- Trial name
- PIH-LITHO (NCT07549152)
- Testing
- Pre-induction Lithotomy Position, Standard Supine Position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trabzon Karadeniz Teknik Universitesi
Pain Management, Dexmedetomidine
Dexmedetomidine Different Doses as Adjuvant to Entropy-assisted General Anesthesia During Functional Endoscopy Sinus Surgery.
The aim of work to assess the effect of different doses of Dexmedetomidine when used as an adjuvant to entropy-guided general anesthesia on the intraoperative surgical field quality, inhaled anesthesia consumption and…
- Conditions
- Pain Management, Dexmedetomidine, Anesthesia
- Trial name
- NCT05226325
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Cairo University
Obesity, Bariatric Surgery
Swap Anesthetic Versus Continuous Desflurane in Adults Undergoing Bariatric Surgery
This randomized, parallel-group, non-inferiority clinical trial aims to evaluate whether an anesthetic swap strategy consisting of sevoflurane followed by desflurane 30 minutes before the end of surgery is non-inferior to…
- Trial name
- SWAP (NCT07748247)
- Testing
- Desflurane, Sevoflurane-Desflurane
- Where
- Chile
- Volunteers
- 82 people
- Sponsor
- Clínica Dávila
Hypotension
TAPSE/PASP Anesthesia
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function.
- Trial name
- TAPSE/PASP (NCT06237543)
- Testing
- hypotension
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Aydin Adnan Menderes University
Postoperative Complications
Korean Version of the "Quality of Recovery 15" After General Anesthesia
The aim of this study is to test the Korean version of QoR-15 for its validity and clinical acceptability and feasibility.
- Trial name
- NCT04169087
- Testing
- QoR-15
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Change of Tempromandibular Joint Function With Supra Glottic Airway Devices
Effect Of Supraglottic Airway Devices On The Tempromandibular Joint Function Following Prolonged General Anesthesia
Effect Of Supraglottic Airway Devices On The Tempromandibular Joint function Following Prolonged General Anesthesia
- Trial name
- NCT05204914
- Testing
- Supra glottic airway devices
- Volunteers
- 60 people
- Sponsor
- Sohag University
Airway Management, Learning Curve
Comparison Between the I-gel and Protector Supraglottic Airway Devices
This study aims to compare the learning curves of two different laryngeal mask airway devices, by evaluating their placement in adult patients performed by anesthesiology residents
- Trial name
- NCT06938308
- Testing
- LMA Igel, LMA Protector
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nikolopoulou Maria Zozefin
General Anesthetics Toxicity, Neurodevelopment
Neurodevelopment of Infants Exposed to General Anesthesia: a Multi-center Investigation
Numerous preclinical evidence has confirmed that most commonly-used general anesthetics can affect neurodevelopment of young animals adversely, causing both structural defect of brain and cognitive impairment.
- Conditions
- General Anesthetics Toxicity, Neurodevelopment, Infant
- Trial name
- GENIUS (NCT03629093)
- Testing
- General Anesthetics
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Huashan Hospital
Anesthesia
The Efficacy of Isocapnic Hyperpnoea to Accelerate Recovery After General Anesthesia With Sevoflurane
The twilight phase between being asleep and awake during recovery from anesthesia is a precarious time fraught with risks to the post-operative patient.
- Trial name
- NCT00242671
- Testing
- Isocapnic Hyperponea
- Where
- Canada
- Sponsor
- University Health Network, Toronto