Clinical trials: Anesthesia, Local
Photobiomodulation Therapy
Reversal of Anaesthesia with Diode Laser
Background: After local anesthesia, which is frequently used in pediatric dentistry, long-term soft tissue numbness can cause various problems.
- Trial name
- NCT06841120
- Testing
- Actual laser application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Pain Management, Local Anaesthesia
Effectiveness of DentalVibe in Reducing Injection Pain and Anxiety During Local Anaesthesia in Children
The aim of this study is to determine the effectiveness of DentalVibe (DV) in reducing injection pain and anxiety associated with local anaesthesia in paediatric patients.
- Trial name
- NCT03445182
- Testing
- Local anaesthesia with conventional syringe, Local anaesthesia with conventional syringe + Dentalvibe
- Where
- Bulgaria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Regional Anesthesia Morbidity, Cesarean Section Complications
Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia
General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn.
- Conditions
- Regional Anesthesia Morbidity, Cesarean Section Complications, Local Anesthetic Complication
- Trial name
- RAMCES (NCT05233462)
- Testing
- standardized dose, adjusted dose
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Caen
Pain Management
Pain Reduction Using Vibration and Topical Anesthesia
The goal of this clinical trial is to study if a powered toothbrush providing vibrations compared with 20% benzocaine topical gel is more effective in reducing pain before local anesthetic injections in children aged 6-12 years…
- Trial name
- TG-EB-Eff (NCT06804616)
- Testing
- 20% benzocaine Gel, Powered Toothbrush
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Anesthesia, Local
Comparing Analgesic Effects of Three Ultrasound Guided Regional Anesthetic Techniques in Pediatrics
This study evaluates analgesic effects of ultrasound-guided (USG) regional anesthetic techniques; caudal block , transversus abdominis plane (TAP) block and quadratus lumborum block (QLB) by comparing postoperative pain scores […
- Trial name
- NCT03780790
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Istanbul University
Molar-Incisor Hypomineralization
Evaluation of Different Anesthesias in Children With Molar Incisor Hypomineralization
In children with molar-incisor hypomineralization (MIH), insufficient depth of anesthesia can lead to increased anxiety and behavior management problems, which may negatively affect the quality of restorations.
- Trial name
- NCT07268157
- Testing
- Computer-controlled anesthesia device (SleeperOne), Conventional injection technique
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Canan Bayraktar Nahir
Serratus Anterior Plane Block, Pain, Postoperative
Effect of Different Local Anesthetic Volumes of Serratus Anterior Plan Block After Video-Assisted Thoracoscopic Surgery
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Serratus Anterior Plane Block, Pain, Postoperative, Thoracic Surgery, Video-Assisted, Local Anesthetic
- Trial name
- NCT05255536
- Testing
- Serratus Anterior Plan Block with 20 ml, Serratus Anterior Plan Block with 30 ml
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Pain, Postoperative
Preemptive Local Anesthesia in Vaginal Surgery
Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a…
- Trial name
- NCT00318292
- Testing
- bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Regional Anesthesia, Hypospadias
Ultrasound-guided PNB and DPNB for Pediatric Distal Hypospadias Surgery
Hypospadias repair is a urological surgical operation that is very painful in the postoperative period and requires long-term analgesia.
- Trial name
- NCT04668183
- Testing
- Pudendal nerve block group, Dorsal penile nerve block group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Healthy
EEG and Auditory Evoked Potentials During Local Anesthesia
The aim of the present study was to investigate the sensitivity of AEP (auditory evoked potentials) to muscular artefacts using sedation and local anesthesia.
- Trial name
- NCT00408941
- Testing
- Propofol, Prilocaine
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Postoperative Pain
Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery
Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a…
- Trial name
- NCT05743231
- Testing
- interpectoral area block + serratus anterior area block group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Underdosing of Local Anesthetics, Initial Encounter
Formulations of Liposomal Local Anesthetics
This blinded cross-over study aim to evaluate the efficacy of liposome-encapsulated ropivacaine formulation for dental anesthesia.
- Trial name
- NCT01307969
- Testing
- Ropivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Lumbar Spinal Fusion
Efficacy of TLIP Block for Postoperative Analgesia of Lumbar Spinal Fusion
Spinal surgery is associated with severe pain in the immediate postoperative period. In a recent study evaluating pain intensity on the first day after surgery in a large range of surgical procedures, among the six most painful…
- Trial name
- ETLA (NCT04593953)
- Testing
- TLIP
- Where
- 2 sites in France
- Volunteers
- 94 people
- Sponsor
- CMC Ambroise Paré
Bladder Injury
Preventing the Obturator Nerve Reflex
The key objective of this study is to compare success rates of ultrasound guided obturator nerve block and anatomic landmark guided obturator nerve block as determined by neuromonitoring endpoints and surgeon observations.
- Trial name
- NCT01547637
- Testing
- Obturator nerve block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Anesthesia Education
Expert Behaviors USGRA
Expert-performance begins by focusing specifically on the end-product of training and experience in the hands of the expert. By defining expert behaviors and techniques, investigators can guide learners and non-expert…
- Trial name
- NCT04454801
- Volunteers
- 190 people
- Sponsor
- University Health Network, Toronto
Discharge Time, Ambulatory Surgery
Different Local Anesthetic Volumes for Unilateral Spinal Anesthesia
Varicose veins are irreversible and abnormal enlargement of the veins. These veins appear and there are curled swellings under the skin in the feet and legs. Complaints increase when standing and sitting for long periods.
- Conditions
- Discharge Time, Ambulatory Surgery, Spinal Anesthesia
- Trial name
- NCT06527430
- Testing
- 4 mg bupivacaine, 6 mg bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Methemoglobinemia
Methemoglobinemia After Liposuction - Diagnostic by Pulse Oximetry and Blood Gas Analysis.
Tumescent local anesthesia is a procedure which is frequently performed for plastic cosmetic surgical procedures such as liposuction.
- Trial name
- NCT01766999
- Volunteers
- 133 people
- Sponsor
- University Hospital Schleswig-Holstein
Perfusion Index, Upper Extremity Surgery
Comparison of 90° and 120° Arm Positions in Costoclavicular Block
The costoclavicular approach of the infraclavicular brachial plexus block is widely used for upper extremity surgeries due to its reliable anatomy and high success rates.
- Conditions
- Perfusion Index, Upper Extremity Surgery, Brachial Plexus Block, Regional Anaesthesia
- Trial name
- COSTO-RCT (NCT07586670)
- Testing
- Costoclavicular Brachial Plexus Block
- Volunteers
- 106 people
- Sponsor
- Ankara Etlik City Hospital
Carpal Tunnel Syndrome
WALANT Versus Local Anesthesia With Tourniquet for Carpal Tunnel Decompression
This multicenter, randomized, double-blinded controlled trial compared two local anesthetic techniques for open carpal tunnel decompression in adults.
- Trial name
- WALANT vs LA-T (NCT07617064)
- Testing
- WALANT technique for carpal tunnel decompression, Local anesthesia with tourniquet for carpal tunnel decompression
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Misr University for Science and Technology