Clinical trials: Anemia, Iron-deficiency
Iron Deficiency Anemia
Efficacy Study of Intravenous Iron Preparation to Iron Deficiency Anemia
The purpose of this study is to confirm the non-inferiority of Z-213 compared to Saccharated Ferric Oxide using the maximum change in Hb from baseline over 12 weeks in patients with Iron-deficiency Anemia (IDA)
- Trial name
- NCT02731534
- Testing
- Z-213, Saccharated Ferric Oxide
- Where
- Japan
- Volunteers
- 238 people
- Sponsor
- Zeria Pharmaceutical
Iron Deficiency
Strategies to Reduce Iron Deficiency
The prevalence of iron deficiency in blood donors has been demonstrated to be a direct consequence of repeat blood donations. Given the adverse effects of iron deficiency, it is priority to implement programs to remediate iron…
- Trial name
- STRIDE (NCT02245321)
- Testing
- Ferrous gluconate- 19 mg, Ferrous gluconate- 38 mg, Letter Group- Information Provided
- Where
- 4 sites in United States
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- Westat
Anemia, Iron Deficiency
Effectiveness of Iron-Fortified Milk on Iron Status and Anemia in Young Children in Mexico
Iron deficiency and anemia in infants and young children impair neurodevelopment. Efficacious interventions for reducing the prevalences of iron deficiency and anemia, under controlled conditions, are available.
- Conditions
- Anemia, Iron Deficiency, Stunting
- Trial name
- NCT00508131
- Testing
- Whole Cows Milk
- Where
- Mexico
- Volunteers
- 798 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Iron Deficiency Anaemia, Iron Deficiency Anemia
Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose or Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia
The trial was designed to evaluate the incidence of unintended hypophosphatemia (low level of phosphate in the blood) in subjects with iron deficiency anaemia (IDA).
- Trial name
- NCT03237065
- Testing
- Iron isomaltoside/ferric derisomaltose, Ferric carboxymaltose
- Where
- 15 sites in United States
- Volunteers
- 122 people
- Sponsor
- Pharmacosmos A/S
Pulmonary Arterial Hypertension, Iron Deficiency
IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients
This study will establish whether intravenous iron replacement has clinical benefit in idiopathic pulmonary arterial hypertension.
- Trial name
- NCT01447628
- Testing
- Saline, Ferinject or CosmoFer
- Where
- 5 sites in China, Germany and 1 more
- Volunteers
- 56 people
- Sponsor
- Imperial College London
Anemia, Iron-Deficiency
Non-invasive Optical Detection of Iron Deficiency
This study aims to evaluate a prototype device detecting zinc protoporphyrin-IX fluorescence non-invasively from the intact oral mucosa. Zinc protoporphyrin-IX is an established indicator of iron deficiency.
- Trial name
- NCT02310607
- Testing
- Not an interventional study
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Klinikum der Universitaet Muenchen, Grosshadern
Anemia of Chronic Kidney Disease
PBF-1681 (Ferric Citrate) for the Treatment of IDA in Patients With NDD-CKD
To assess the safety and effectiveness of PBF-1681 for the treatment of Iron Deficiency Anemia in patients with Non-Dialysis Dependent Chronic Kidney Disease.
- Trial name
- NCT04543812
- Testing
- Ferric citrate
- Where
- 12 sites in Taiwan
- Volunteers
- 141 people
- Sponsor
- Panion & BF Biotech Inc.
Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF)
IRONICA: IRON Repletion In Heart Failure - A Comparison of Oral and IV Approaches
The goal of this clinical trial is to learn which iron treatment works better for adults with congestive heart failure and low iron levels: intravenous (IV) iron given through a vein or oral (PO) iron taken by mouth.
- Conditions
- Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF), Heart Failure With Preserved Ejection Fraction (HFPEF), Iron Deficiency
- Trial name
- IRONICA (NCT07053475)
- Testing
- Ferric Carboxymaltose, Ferrous Sulfate
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Syed Hamza Mufarrih
Iron-deficiency
EXPLorative Data Collection for Patient chAracterIzation, treatmeNt Pathways and Outcomes of IRON Preparations
By describing the characteristics of iron deficiency (ID) patients treated with various oral or intravenous iron formulations and their outcomes, this registry will provide the medical community with important information to…
- Trial name
- EXPLAIN-IRON (NCT03382275)
- Testing
- Iron Supplement
- Where
- 2 sites in Germany
- Volunteers
- 51 people
- Sponsor
- GWT-TUD GmbH
Anemia
Iron Dextran Versus Oral Iron for Treating Iron Deficiency Anemia in Pregnant Women
Iron deficiency is the most prevalent nutritional deficiency and the most common cause of anemia .It is characterized by a defect in hemoglobin synthesis, resulting in red blood cells that are abnormally small (microcytic) and…
- Trial name
- NCT03212781
- Testing
- Iron dextran, Ferrous Fumarate
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Iron Deficiency Anemia, Inflammatory Bowel Disease
Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With IBD
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) characterized by chronic inflammation limited to the mucosal layer of the colon. Anemia is a consistent clinical feature of IBD.
- Trial name
- NCT02774057
- Testing
- Captafer®, Iron Sulfate
- Where
- Lebanon
- Volunteers
- 20 people
- Sponsor
- American University of Beirut Medical Center
Iron Deficiency Anemia, Malaria
Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum
The purpose of this study is to perform laboratory based studies to determine if the growth and development of the malaria parasite is effected by iron status of its host (the person infected with the malaria parasite).
- Trial name
- NCT01027663
- Testing
- Iron Supplement
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Iron Deficiency
Iron and the Breast-Fed Infant: Iron Status and Two Regimens of Iron Supplementation
Normal breastfed infants can develop iron deficiency by 6 months of age. This trial tested the hypothesis that regular provision of a source of iron beginning at 4 months of age improves iron status and could prevent iron…
- Trial name
- BFe01B1 (NCT00760890)
- Testing
- Fer-In-Sol (ferrous sulfate), Iron fortified cereal
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health (NIH)
Anemia, Iron Deficiency, Pregnancy Anemia
Iron Deficiency Anemia in the Second and Third Trimester of Pregnancy
Iron deficiency is the most frequent cause of anemia during pregnancy and of maternal blood transfusion during the post-partum period.
- Trial name
- PESO (NCT07163390)
- Testing
- Sideral Folico
- Volunteers
- 82 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Iron Deficiency Anemia
A Study Comparing Two Ferric Carboxymaltose Formulations in Patients With Iron Deficiency Anemia
This study will evaluate bioequivalence of two formulations of Ferric Carboxymaltose as measured by serum total iron, in adult patients with iron deficiency anemia.
- Trial name
- NCT03399084
- Testing
- Ferric carboxymaltose
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Sandoz
Iron Deficiency, Iron Deficiency Anemia
Effect of Iron Fortified Wheat Flour on Cognition and Iron Status in Indian School Children
This study is designed to evaluate the efficacy of NaFeEDTA-fortified whole wheat flour in improving cognition, hemoglobin, iron status and total body iron among school children in urban Bangalore.
- Conditions
- Iron Deficiency, Iron Deficiency Anemia, Cognition
- Trial name
- NCT00741143
- Testing
- Fortification of wheat flour with NaFeEdta
- Where
- India
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- St. John's Research Institute
Acute Myocardial Infarction
Iron Deficiency in Acute Myocardial Infarction: Prevalence Pilot Study
Acute Myocardial Infarction (heart attacks) affect about 86000 people each year in the UK. Given this large number of people, it is important that health teams look at ways to ensure the best care to improve outcomes after a…
- Trial name
- IDAMI Pilot (NCT06457815)
- Where
- 2 sites in United Kingdom
- Volunteers
- 70 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Iron-deficiency, Hypersensitivity Reactions
Characteristics of Patients With Hypersensitivity Reactions to Intravenous Iron Infusions
This study aims to evaluate characteristics of patients with previous hypersensitivity reaction grades I-IV to intravenous ferric carboxymaltose (Ferinject) or to iron sucrose (Venofer) including age, atopy status, previous…
- Trial name
- NCT04359368
- Testing
- collection of patient data
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University Hospital, Basel, Switzerland
Anemia, Iron Deficiency, Colorectal Surgery
Impact of Iron Infusion in Anemic Patients on Their Postoperative Outcome After Colorectal Surgery
In 2005, colorectal surgery in France represented nearly 40,000 procedures per year, of which 80% were scheduled and 70% were for carcinological purposes.
- Trial name
- IRON_PREHAB (NCT05522790)
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Iron Deficiency Anemia
Fermented Iron-rich Supplement in Reducing Anemia
The consequences of iron deficiency anemia in women are enormous, and especially in developing countries, as the condition adversely affects both their productive and reproductive capabilities.
- Trial name
- FISRA (NCT02037724)
- Testing
- supplement containing 60 mg iron sulfate, iron rich food supplement (60 mg iron), iron rich food supplement (10 mg iron)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Ghana