Clinical trials: Anemia, Iron-deficiency
Iron-deficiency Anemia
Umbilical Cord Clamping and Infant Iron Status
The aim of the study was to determine whether delayed umbilical cord clamping, as compared to early umbilical cord clamping, improves infant iron status at 6 months of age.
- Trial name
- NCT00298051
- Testing
- Delayed umbilical cord clamping
- Where
- Mexico
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Anemia, Iron Deficiency
Effect of Timing of Umbilical Cord Clamping on Anaemia at 8 and 12 Months and Later Neurodevelopment
The investigators plan a study to randomize 540 children in Nepal to early (≤30 seconds) or late (≥180 seconds) clamping of the umbilical cord at birth.
- Conditions
- Anemia, Iron Deficiency, Neonatal Jaundice
- Trial name
- NCT02222805
- Testing
- Early (≤30 seconds) cord clamping, Delayed (≤180 seconds) cord clamping
- Where
- Nepal
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Anemia, Iron Deficiency, Uterine Bleeding
IV Iron Trial for Anemia Related to Uterine Bleeding in Female Patients Presenting to the Emergency Department
The primary aim of this randomized trial is to assess the efficacy of IV Ferric Derisomaltose vs Oral Iron in the management of women with severe Iron Deficiency Anemia due to Uterine Bleeding in the emergency department.
- Trial name
- NCT05304442
- Testing
- Ferric Derisomaltose 1000 Mg in 10 mL INTRAVENOUS SOLUTION [Monoferric], Ferrous Sulfate 65 mg elemental iron (325 mg tablets)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Anemia, Iron Deficiencies
Postoperative Intravenous Ferric Derisomaltose for Prevention of Long-term Anemia After Cardiac Surgery
Postoperative anemia is highly prevalent among patients undergoing cardiac surgery and is associated with delayed functional recovery, increased morbidity, and impaired long-term outcomes.
- Conditions
- Anemia, Iron Deficiencies, Iron Deficiency Anemia, Cardiac Surgery
- Trial name
- NCT07238972
- Testing
- Ferric derisomaltose
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Yonsei University
Obesity, Iron Deficiency
Study of Sleeve Gastrectomy on Iron Intestinal Absorption in Morbidly Obese Patients
Subject: Evaluation of the impact of obesity surgery by sleeve gastrectomy on intestinal iron absorption of morbid obese subjects.
- Trial name
- FORBES (NCT01483768)
- Testing
- Sleeve gastrectomy for morbid obesity
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Iron Deficiency
Improving Iron Levels in Female Endurance, Intermittent, and Power/Strength Athletes Aged 16-35
The goal of this clinical trial is to learn if different types and doses of oral iron supplements can improve iron levels, athletic performance, and gut health in young female athletes with low iron stores.
- Trial name
- FeSc2 (NCT06942208)
- Testing
- Low-dose iron (ferrous sulfate), Yeast-bound iron (ferrous sulfate), High-dose iron (ferrous sulfate)
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Calgary
IDA in the Post-bariatric Surgical Patient
Intravenous (IV) Versus Oral Iron Treatment of Iron Deficiency Anemia in the Post-operative Bariatric Surgical Patient
The aim of the study is to compare two accepted treatments for iron deficiency anemia (oral ferrous sulfate and intravenous ferumoxytol) for efficacy and speed of response in the treatment of iron deficiency anemia (IDA) in the…
- Trial name
- NCT03777514
- Testing
- Ferumoxytol, Ferrous sulfate, Oral vitamin C
- Sponsor
- Johns Hopkins University
Anemia of End Stage Renal Disease
Prospective Observational Study of Erythropoietin-Iron Interaction in Anemia of Renal Disease
The purpose of this study is to prospectively collect data on doses of Erythropoietic Stimulating Agents (ESA) and Intravenous Iron, and the markers of erythropoietic activity and iron status.
- Trial name
- NCT01719146
- Testing
- Specimen collection
- Where
- 3 sites in United States
- Volunteers
- 134 people
- Sponsor
- University of Louisville
ADHD, Iron-deficiency
Impact of Iron Supplementation Treatment on Brain Iron Concentrations
The goal of the present study is to provide novel data to evaluate brain iron concentration as a mediator of the association between iron supplementation treatment and improvement in symptoms of ADHD and RLS in children…
- Conditions
- ADHD, Iron-deficiency, Restless Legs Syndrome, Periodic Limb Movement Sleep Disorder
- Trial name
- NCT04144790
- Testing
- ferrous sulfate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Iron-deficiency, Colorectal Cancer
Effects of Intravenous Administered Iron in Non-anemic Iron Deficient Patients With Colorectal Cancer
This double-blinded clinical randomized trial with a 1:1 recruitment ratio between placebo and the active group will aim to investigate the effects of intravenously administered iron in non-anemic iron deficient patients on…
- Trial name
- NAIDIC (NCT05220800)
- Testing
- Iron(III)isomaltoside
- Where
- 3 sites in Denmark
- Volunteers
- 134 people
- Sponsor
- Zealand University Hospital
Iron-deficiency
Prevalence Study of Iron Deficiency in Patients With Cancer
Despite its high prevalence, a recent study conducted by Prof. Cacoub (unpublished) on the french national health insurance database showed that iron deficiency was an underdiagnosed and under-treated co-morbidity.
- Trial name
- CARENFER ONCO (NCT03924271)
- Testing
- Iron deficiency testing
- Volunteers
- 1,200 people
- Sponsor
- VIFORFRANCE
Iron-deficiency
Iron Absorption From Encapsulated Iron Sulphate in Microspheres
Food fortification has shown to be efficacious to alleviate the burden of micronutrient deficiencies. Ensuring the bioavailability of iron and maintaining the sensory quality and stability of the fortified food and other added…
- Trial name
- NCT03332602
- Testing
- free FeSO4, free FeSO4 and empty microspheres, free FeSO4 and hylauronic acid
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
IDA - Iron Deficiency Anemia, Anemia
Iron Deficiency Anemia (IDA) and the Brain
This is a trial with an observational and an interventional arm, in patients with moderate to severe anemia and control subjects.
- Conditions
- IDA - Iron Deficiency Anemia, Anemia, Iron Deficiency Anemia, Anemia, Iron Deficiency
- Trial name
- IDA (NCT05929729)
- Testing
- Ferric derisomaltose, NovaFerrum
- Where
- 4 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Non-Anemic Iron Deficiency
Risk of Anemia and Effects of Oral Iron Therapy in Non-Anemic Iron-Deficient Women (18-55 Years)
This study investigates the risk of anemia development in women aged 18-55 years with non-anemic iron deficiency and evaluates the clinical effects of oral iron therapy.
- Trial name
- NAID-F (NCT07263529)
- Testing
- Dietary Intervention (2 months), Oral Elemental Iron (Ferrous Sulfate) 80 mg/day
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Anemia, Iron-Deficiency, Cognitive Performance
Iron-fortified Lentils to Improve Iron (Fe) Status in Bangladesh
We designed a double-blind, community-based, cluster-randomized control trial which will test to establish novel evidence on the efficacy of iron-fortified lentil in improving body Fe status of non-pregnant adolescents in rural…
- Conditions
- Anemia, Iron-Deficiency, Cognitive Performance, Iron-deficiency
- Trial name
- NCT03516734
- Testing
- Iron fortified lentils, Non Iron-fortified lentils, Usual Intake
- Where
- Bangladesh
- Volunteers
- 1,252 people, healthy volunteers welcome
- Sponsor
- Carol Henry
Hematologic Pregnancy Complications
Doubling the Iron Dose to Prevent IDA in Twin Pregnant Women
In twin pregnancies, the maternal iron demands are magnified, estimated at 1.8 times more than in singleton pregnancies due to greater maternal red blood cell mass and plasma volume expansion as well as increased fetal and…
- Trial name
- IDA (NCT03836703)
- Testing
- Feroglobin single daily use, Feroglobin twice daily dose
- Where
- Egypt
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pregnancy, Helicobacter Pylori Infection
Effects of Dietary Heme/Non-heme Iron and Helicobacter Pylori (Hp) Infection on Maternal Iron-deficiency Anemia and Fetal Growth Outcomes
Iron deficiency is considered one of the main nutritional deficiency disorders despite the apparent availability of a high-quality diet even in developed countries, and Iron deficiency anemia (IDA) is the most common form of…
- Conditions
- Pregnancy, Helicobacter Pylori Infection, Iron-Deficiency Anemia
- Trial name
- NCT01071759
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- E-DA Hospital
Iron Deficiency, Anemia
Iron Absorption From Rice Fortified With Ferric Pyrophosphate
Ferric pyrophosphate (FePP) is a water-insoluble, food grade iron compound used to fortify rice, infant cereals and chocolate-drink powders as it causes no organoleptic changes to the food vehicle.
- Conditions
- Iron Deficiency, Anemia, Iron Deficiency Anemia
- Trial name
- NCT02176759
- Testing
- Administration of rice fortified with regular FePP, Administration of rice fortified with regular FePP with citrate added during extrusion, Administration of rice fortified with regular FePP and citrate added at consumption
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Heart Failure, Anemia
Oral Iron for the Management of Iron Deficiency Anemia in SGLT2i-Treated Heart Failure Patients
People with heart failure often have anemia caused by low iron levels. Ongoing inflammation in heart failure can impair iron absorption, making oral iron therapy less effective.
- Trial name
- NCT07708025
- Testing
- Oral iron supplementation
- Where
- Portugal
- Volunteers
- 55 people
- Sponsor
- Universidade do Porto
Hypoferritenemia Without Anemia (HWA), Iron Deficiency Without Anemia)
Hypoferritinemia Without Anemia Among Reproductive Age Females
The goal of this randomized controlled trial is to compare the treatment outcomes of oral iron supplementation (Group A) versus Intravenous (IV) iron supplementation (Group B) versus no treatment (Group C) on the serum ferritin…
- Trial name
- NCT06437080
- Testing
- Iron III Hydroxide Polymaltose Complex eq. to Elemental Iron, 100 mg, Ferric Carboxymaltose
- Where
- 4 sites in Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Akram Medical Complex