Clinical trials: Anastomotic Leakage
Blood Loss, Intensive Care
D2 Versus D3 Dissection in Laparoscopic Right Hemicolectomy
Evaluating the differences between D2 and D3 lymphadenectomy in laparoscopic right hemicolectomy in patients with right cancer colon post-operative outcome, intra-operative blood transfusion, post-operative ICU admission…
- Conditions
- Blood Loss, Intensive Care, Anastomotic Leakage, Lymph Node Disease
- Trial name
- NCT06049758
- Testing
- LAPAROSCOPIC RIGHT HEMICOLECTOMY procedure (intervention), Enoxaparin 40 Mg/0.4 mL Injectable Solution, Levofloxacin 500mg
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Rectum Cancer, Stoma Colostomy
Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer
RATIONALE: Colorectal cancer is one of the most common cancers. However, approaches to minimize surgical trauma, preserve anal function, avoid abdominal stoma, and improve quality of life for patients with ultralow rectal cancers…
- Conditions
- Rectum Cancer, Stoma Colostomy, Faecal Incontinence, Leakage, Anastomotic
- Trial name
- NCT05245565
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai 10th People's Hospital
Anastomotic Leakage
The Relationship Between Drainage Fluid and Anastomotic Leakage After Colorectal Cancer Surgery
A prospective and analytical study on the detection of early anastomotic leakage by abdominal drainage fluid after colorectal cancer surgery. pay attention to indicators including bilirubin
- Trial name
- NCT05191602
- Testing
- drainge fluid
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Southwest Hospital, China
Anastomotic Leakage, Colorectal Cancer
Predictive Factors for Anastomotic Leakage After Colorectal Surgery
Rationale: Colorectal cancer is the fourth most common cause of cancer death worldwide, estimated to be responsible for almost 610,000 deaths in 2008.
- Conditions
- Anastomotic Leakage, Colorectal Cancer, Anastomotic Leak, Colorectal Neoplasms
- Trial name
- REVEAL (NCT02347735)
- Testing
- No interventions, only data collection
- Where
- 4 sites in Netherlands
- Volunteers
- 774 people
- Sponsor
- Maastricht University Medical Center
Postoperative Peritonitis, Anastomotic Leakage
Delayed Small-Bowel Anastomosis in Patients With Postoperative Peritonitis
Surgical management results for 114 patients with postoperative peritonitis due to small-bowel perforations, necrosis, and anastomotic leakage were comparatively analyzed.
- Conditions
- Postoperative Peritonitis, Anastomotic Leakage, Intestinal Perforation Small
- Trial name
- Peritonitis (NCT03690687)
- Testing
- Primary anastomosis, Delayed anastomosis, Enterostomy
- Volunteers
- 114 people
- Sponsor
- Andrey Nikolayevich Zharikov
Anastomotic Leakage, Rectal Neoplasms
Use of the TDT for Prevention of Anastomotic Leakage After Laparoscopic Anterior Resection for Rectal Cancer
The rate of anastomotic leakage after laparoscopic anterior resection（LAR） for medium \& low rectal cancer is still high. the transanal drainage tube (TDT) was thought to be useful for deduce the rate.
- Trial name
- NCT02686567
- Testing
- with TDT, without TDT
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Third Military Medical University
Anastomotic Leakage
Drainage Fluid Biomarkers and Anastomotic Leakage in Colorectal Surgery. A Monocentric Prospective Observational Study
Anastomotic leakage (AL) is one of the most feared intra-abdominal septic complications (IASC) after colorectal surgery. It is defined as the leak of intestinal content due to an anastomotic dehiscence.
- Trial name
- ALbiomarkers (NCT04846283)
- Testing
- Elective or emergency colorectal surgery for cancer, diverticular disease, inflammatory bowel-disease or reversal of Hartmann's procedure
- Where
- Italy
- Volunteers
- 207 people
- Sponsor
- University of Palermo
Microdialysis, Ischemia
Local Metabolism of the Gastric Tube Reconstruction After Esophagectomy
Postoperative surveillance of local metabolism of the surgical reconstruction after esophagectomy by means of Microdialysis. Dialysate is collected continuously for seven postoperative Days.
- Conditions
- Microdialysis, Ischemia, Anastomotic Leakage
- Trial name
- NCT04319835
- Testing
- OnZurf Probe
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Anastomotic Leakage
Anastomotic Leakage Following Laparoscopic Resection for Rectal Cancer
Anastomotic leak (AL) is a breakdown of a suture line in a surgical anastomosis with a subsequent leakage of the luminal content.
- Trial name
- NCT02718729
- Testing
- Laparoscopic resection for rectal cancer
- Where
- 2 sites in Egypt, Italy
- Volunteers
- 59 people
- Sponsor
- Mansoura University
Ileostomy - Stoma, Ileostomy; Complications
Laparoscopic Surgery of Rectal Cancer and Ileostomy
Elective diverting ileostomy may reduce consequences of anastomotic failure in laparoscopic TME. Aiming to evaluate the effectiveness of elective diverting ileostomy, its impact on the incidence and clinical behavior of…
- Conditions
- Ileostomy - Stoma, Ileostomy; Complications, Leakage, Anastomotic
- Trial name
- NCT04169425
- Testing
- elective diverting ileostomy
- Volunteers
- 150 people
- Sponsor
- Campus Bio-Medico University
Anastomotic Leakage
SEAL Registry - European Registry for the Effectiveness of LifeSeal® Kit
This study will assess the effectiveness of commercially available LifeSeal® Kit as measured by the incidence of post-operative clinical anastomotic leak rates in subjects undergoing low and ultralow anterior resection with an…
- Trial name
- NCT02881359
- Testing
- LifeSeal® Kit
- Where
- 8 sites in Belgium, Netherlands
- Volunteers
- 200 people
- Sponsor
- LifeBond Ltd.
Anastomotic Leakage in Colon Surgery
Predictive Value of Procalcitonin, CRP, Drain Fluid Culture, Il-6 and Tnf-α in Anastomotic Leakage
Evaluating predictive value of serum procalcitonin, C-Reactive Protein, drain IL-6 and TNF-alpha for anastomotic leakage in post-operative period.
- Trial name
- NCT02361918
- Testing
- Colon surgery
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Anastomotic Leakage, Esophageal Cancer
Mediastinal Microdialysis in Patients With Oesophageal or Cardia Cancer Treated by Resection
Postoperative anastomotic leakage is a serious complication in patients with oesophageal or cardia cancer. Early diagnosis and treatment are mandatory.
- Trial name
- NCT00686569
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Odense University Hospital
Anastomotic Leakage
The Optimal Width of Gastric Conduit for Minimally Invasive Esophagectomy: Wide or Narrow?
The study hypothesized that a narrow gastric conduit(less than 3cm in width) would minimize anastomotic leakage following minimally invasive esophagectomy.
- Trial name
- NCT01696682
- Testing
- Narrowed Gastric Conduit, Widened Gastric Conduit
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Mediastinitis, Esophageal Neoplasms
Endoscopic-vacuum Assisted Closure of Intrathoracic Postsurgical Leaks
The purpose of this study is to determine the short and long term outcome of endoscopic vacuum assisted closure of intrathoracic postsurgical leaks.
- Conditions
- Mediastinitis, Esophageal Neoplasms, Anastomotic Leakage
- Trial name
- EVACoIL (NCT00876551)
- Testing
- Endoscopic vacuum assisted closure
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Hannover Medical School
Anastomotic Leakage
Oral Anti-Infective Agent for Esophageal Anastomotic Leakage
Anastomotic leakage is still to be a major cause of considerable morbidity and mortality after esophagectomy and gastric pull up for esophageal carcinoma.
- Trial name
- NCT00942526
- Testing
- Mycostatin oral suspension, Water
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Esophageal Cancer, Anastomotic Leakage
Detection of Anastomotic Leakage After Esophageal Surgery
Anastomotic leakage is a major complication in esophageal surgery. Although contrast swallow is the current standard to exclude anastomotic leakage postoperatively, endoscopy may be superior.
- Trial name
- NCT00642525
- Testing
- Contrast swallow radiography, endoscopy
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Heidelberg University