Clinical trials: Analgesic
Trigeminal Neuralgia
Analgesic Effect of Ultrasound Guided Maxillary Nerve Block in Trigeminal Neuralgia
This is a study about the dynamics and effects of ultrasound guided maxillary nerve block in trigeminal neuralgia
- Trial name
- NCT06129071
- Testing
- US guided block of maxillary nerve
- Where
- Croatia
- Sponsor
- Varazdin General Hospital
Rib Fractures, Pain, Acute
Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma
The main goal of this clinical trial is to learn if light therapy improves pain and inflammation in adults with painful rib fractures.
- Trial name
- BLAASTT (NCT06626334)
- Testing
- Bright Blue Light, Bright Full-Spectrum (White) Light, Usual Ambient Light
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Rebecca E Kotcher, MD
Lumbar Microdiscectomy Surgery, Lumbar Erector Spinae Plane Block
Comparison of the Analgesic Efficacy of Erector Spinae Plane Block in Lumbar Microdiscectomy Surgeries
Comparison of the Analgesic Efficacy of Lumbar Erector Spinae Plane Block and Sacral Erector Spinae Plane Block in Lumbar Microdiscectomy Surgeries
- Conditions
- Lumbar Microdiscectomy Surgery, Lumbar Erector Spinae Plane Block, Sacral Erector Spinae Plane Block, Postoperative Pain
- Trial name
- NCT07652177
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Video Assisted Thoracoscopic Surgery, Lobectomy
SERRATHOR TRIAL : Interest of the Novel Serratus Plane Block in Post Operative Analgesia After Video-Assisted Thoracoscopic Lobectomy
Pain after thoracic surgery remains a challenge for anesthetists. Although VATS for lobectomy is associated with fewer complications compared to thoracotomy, pain after VATS needs to be treated with opioids.
- Conditions
- Video Assisted Thoracoscopic Surgery, Lobectomy, Pain Post Operative, Regional Anesthesia
- Trial name
- SERRATHOR (NCT03867695)
- Testing
- Ropivacaine, sterile saline
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Inguinal Hernia, Postoperative Pain
Comparing Erector Spinae Plane (ESP) and Transversus Abdominis Plane (TAP) Block in Inguinal Hernia
The Erectore Spinae Plane Block (ESP Block) is a recently described technique for regional anesthesia that has shown promising results in the treatment of pain after thoracic surgery.
- Conditions
- Inguinal Hernia, Postoperative Pain, Anesthesia, Local, Anesthesia Complication
- Trial name
- TAPESP (NCT04750512)
- Testing
- ESP block, TAP block
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ghielmini Enea
Infertility
Optimizing Patient Analgesic Experience During IVF
This study is for patients undergoing In Vitro Fertilization (IVF). The investigators are studying the best way to control pain during the egg retrieval process.
- Trial name
- NCT01814657
- Testing
- Lidocaine hydrochloride (HCl) 1% solution, Sterile Normal Saline%
- Where
- Canada
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Pain
Analgesic Efficacy of Local Anesthetic Transversus Abdominis Plane (TAP) Blocks in Abdominal Surgery
The aim of the study is to establish the efficacy of local anaesthetic TAP (transversus abdominis plane) blocks in providing pain relief in the first 24hrs following open or laparoscopic elective abdominal colorectal operations.
- Trial name
- NCT00682136
- Testing
- US-Guided Ropivacaine TAP Block
- Where
- 4 sites in Australia
- Volunteers
- 206 people
- Sponsor
- Hunter Colorectal Research
Surgery, Individuality
The Realtime Detection for Individual Variation of Analgesic ：A Comparison of Sufentanil vs Fentanyl
Purpose: This study aimed to find a quick and timely way to investigate the individual variation of efficacy of opioid analgesic in Chinese patients undergoing elective surgeries.
- Trial name
- NCT01748071
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huazhong University of Science and Technology
Opioid Dependency
A Six-Month Randomized Controlled Trial (RCT) of Probuphine Safety and Efficacy in Opioid Addiction
Probuphine (buprenorphine implant) is an implant placed just below the skin containing buprenorphine (BPN). BPN is an approved treatment for opioid dependence. This study will confirm the efficacy of Probuphine vs.
- Trial name
- NCT01114308
- Testing
- Probuphine (buprenorphine implant), Buprenorphine
- Where
- 20 sites in United States
- Volunteers
- 287 people
- Sponsor
- Titan Pharmaceuticals
Quadratus Lumborum Block, Erector Spinae Plane Block
Analgesic Efficacy of Quadratus Lumborum Block Against Erector Spinae Plane Block in Laparoscopic Sleeve Gastrectomy
The current investigation aimed to assess the postoperative analgesic efficacy of quadratus lumborum block against erector spinae plane block in sleeve gastrectomy surgeries
- Conditions
- Quadratus Lumborum Block, Erector Spinae Plane Block, Sleeve Gastrectomy
- Trial name
- NCT06828497
- Testing
- Technique of posterior quadratus lumborum block (QL 2 block):, Technique of erector spinae plane block:
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Port Said University hospital
Pain
Analgesic Strategies in Newborns Receiving Prostaglandin Therapy
This is a randomised trial comparing the efficacy of 3 different analgesic strategies in newborns on prostaglandin for ductus dependent congenital heart disease.
- Trial name
- NCT00200590
- Testing
- acetaminophen and nalbuphine, acetaminophen and morphine, acetaminophen and reduced dosage of prostaglandin
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Pain, Postoperative
Intraoperative Methadone vs Morphine for Postoperative Pain Control in Patients Undergoing Surgery of the Tibia
The purpose of this study is to determine whether, for surgery of the tibia, one dose of methadone provides better control of pain afterward as compared to morphine, which is the usual drug given to control pain after surgery.
- Trial name
- NCT01430182
- Testing
- Methadone, Morphine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Back Pain, Osteoarthritis
Strategies for Prescribing Analgesics Comparative Effectiveness Trial
Chronic musculoskeletal pain conditions are among the most prevalent conditions in VA primary care. Over the past two decades, improved clinical attention to pain has been associated with exponentially greater use of long-term…
- Trial name
- SPACE (NCT01583985)
- Testing
- Opioid-intensive prescribing strategy, Opioid-avoidant prescribing strategy
- Where
- United States
- Volunteers
- 265 people
- Sponsor
- VA Office of Research and Development
Pain Level, Sleep Quality and Analgesic Consumption in Open Heart Surgery
The Effect of Progressive Relaxation Exercise on Pain Level, Sleep Quality and Analgesic Consumption
Coronary artery bypass graft (CABG) surgery is the process of providing re-oxygenation of the myocardium by anastomosis to the occluded heart coronary with the graft created using certain vessels of the body.
- Trial name
- NCT05727280
- Testing
- Progressive Relaxation Exercise Practices
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Suleyman Demirel University
Rheumatoid Arthritis
Exploiting Leading Edge 7T MRI Brain Imaging to Decipher Olumiant's Mode of Analgesic Action in Rheumatoid Arthritis
The revolution in treatments for rheumatoid arthritis (RA) has transformed patient outcomes, but many patients continue to experience life disabling pain.
- Trial name
- SOAR (NCT05112120)
- Testing
- Olumiant
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- NHS Greater Glasgow and Clyde
Single-level Lumbar Arthrodesis
Intravenous Lidocaine Versus Erector Spinae Plane Block After Lumbar Arthrodesis (LIBERA)
The hypothesis of this study is that intraoperative intravenous lidocaine infusion provides postoperative analgesia and opioid-sparing effects that are at least equivalent to those achieved with a bilateral erector spinae plane…
- Trial name
- LIBERA (NCT07895368)
- Testing
- Single-level posterior lumbar arthrodesis
- Where
- France
- Volunteers
- 90 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Premature Birth, Newborn
Pain Management in Neonatal Intensive Care Units by Studying the Autonomic Balance
Fight against the pain caused by the disease or by the diagnostic and therapeutic procedures is a daily and essential concern for the caregiver neonatologist.
- Trial name
- NIPE-DOL (NCT02764424)
- Testing
- NIPE (MDoloris®)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Fibroadenoma
Analgesic Efficacy of Pulsed Radiofrequency in Non-cyclic Mastalgia
Background: Breast pain, mastalgia or mastodynia, is recognized as an organic benign breast disease. Mastalgia may be bilateral, may be in only one breast or part of one breast, and may radiate to the axilla and down the medial…
- Trial name
- NCT03715413
- Testing
- pulsed radiofrequency of 2nd , 3rd and 4th thoracic dorsal root ganglia., Tamoxifen
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Knee Osteoarthritis (OA), Postoperative Pain
Effect of Adding a Biceps Femoris Short Head Block to Adductor Canal Block for Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is frequently associated with moderate to severe postoperative pain, which may delay mobilization, increase opioid consumption, and impair functional recovery.
- Trial name
- BiFeS-TKA (NCT07803887)
- Testing
- Ultrasound-Guided Adductor Canal Block, Ultrasound-Guided Biceps Femoris Short Head Block
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Antalya Training and Research Hospital
Postoperative Pain
The Analgesic Effect of Transversus Abdominis Plane (TAP) Block Following Radical Prostatectomy
This study is conducted to evaluate different analgesic treatments effect following operation where the prostate gland is surgically removed. The different treatments the investigators wish to investigate is: 1.
- Trial name
- NCT01317368
- Testing
- Naropine
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet