Clinical trials: Analgesia Disorder
Regional Anesthesia
A Randomized Clinical Trial
Acute postoperative pain is a common problem faced by the patient after surgery, most frequently occurring in first 24 hours. Our primary objective was to assess pain score in first 24 hours in PECS block group undergoing…
- Trial name
- NCT03947463
- Testing
- PECS block
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Endometriosis
Letrozole vs Danazol for Endometriosis-Related Pain: Randomized Trial
Background: Endometriosis is a chronic gynecological condition defined by the ectopic presence of endometrial glands and stroma outside the uterine cavity, most commonly diagnosed via laparoscopy.
- Trial name
- LET-DAN RCT (NCT07183787)
- Testing
- Letrozole, danazol
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sidra Salman
Traumatic Injury
Ketamine Low dOse Evaluation on Morphine Consumption in Traumatic Patient
The aim of this study is to demonstrate a significant reduction of at least 25% in opioid consumption at 48 hours of management of severe trauma, while demonstrating non-inferiority in terms of analgesia, in a group of patients…
- Trial name
- KLOE (NCT04833816)
- Testing
- Administration of drug
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Fusion of Spine, Lumbar Region
The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion
Simple explanation and rationale: Recovery after spine surgery is usually accompanied by severe pain which has traditionally been managed with opioids.
- Trial name
- NCT03104816
- Testing
- Acetaminophen IV Soln 10 MG/ML, Acetaminophen, Hydromorphone
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Phantom Limb Pain, Pain, Chronic
Continuous Sciatic Nerve Block vs Epidural Analgesia in Lower Limb Amputation for Postoperative Pain
Controlled clinical trial of two parallel groups, with random assignment 1:1, non-inferiority, blinded for the patient, for who administers the intervention and for who analyzes the data. 112 participants
- Trial name
- Ampupain (NCT05608733)
- Testing
- Epidural catheter, Continuous sciatic nerve block
- Where
- Colombia
- Volunteers
- 112 people
- Sponsor
- Universidad de Antioquia
Elderly, Hip Fracture Surgery
Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery
Delirium is common in the elderly after hip fracture surgery, and is associated with worse outcomes. The investigators hypothesize that, for elderly patients after hip fracture surgery, dexmedetomidine supplemented analgesia can…
- Conditions
- Elderly, Hip Fracture Surgery, Patient-controlled Analgesia, Dexmedetomidine
- Trial name
- NCT04955249
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Peking University First Hospital
Bone Metastases
A Randomized Trial Evaluating Rapid Delivery of Dose Escalated Hypofractionated Radiotherapy for Patients Diagnosed With Bone Metastases for Effective Palliation of Symptoms
The goal of this clinical research study is to learn if 1 large dose of radiation therapy is better at controlling pain from cancer that has spread to the bones than 10 smaller doses of radiation.
- Trial name
- NCT02163226
- Testing
- Hypofractionated Radiation Treatment, One Radiation Treatment, Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 167 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Postoperative, Thoracic Diseases
Liposomal Bupivacaine for Pain Control Following Thoracic Surgery.
The aims of the study are to compare the effectiveness and postoperative outcomes of liposomal bupivacaine vs plain bupivacaine following video-assisted thoracoscopic surgery.
- Conditions
- Pain, Postoperative, Thoracic Diseases, Local Anesthetics Causing Adverse Effects in Therapeutic Use, Opioid Dependence
- Trial name
- NCT03036085
- Testing
- Liposomal bupivacaine, Bupivacaine, Epinephrine
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Endometriosis, Endometriosis Related Pain
Efficacy of Physical Therapy Treatment in Endometriosis and Its Relationship to Adherence Rates.
The main objective of this study is to know if the application of both therapies, neuroscience pain education plus therapeutic exercise will modify pain, catastrophizing and quality of life in endometriosis.
- Conditions
- Endometriosis, Endometriosis Related Pain, Endometriosis, Pain, Endometriosis-related Pain
- Trial name
- NCT06795243
- Testing
- PAIN NEUROSCIENCE EDUCATION AND THERAPEUTIC EXERCISE PROGRAM, USUAL CARE
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- University of Seville
Chronic Pain
The Influence of Therapeutic Tactics of Analgesia on the Long-term Results of Pain Treatment in Patients With Gunshot and Mine-explosive Wounds
Considering that in 82.1% of cases it is not possible to achieve a positive result of treatment, the data of our study will play an important role in the treatment of such patients.
- Trial name
- ITTAL-TRPT (NCT05485116)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 2,215 people
- Sponsor
- Bogomolets National Medical University
Interscalene Block, Suprascapular Nerve Block
Ultrasound Guided Interscalene, Suprascapular and Anterior Glenoid Nerve Blocks on Diaphragmatic Excursion and Analgesia Following Arthroscopic Shoulder Surgery
This study aims to evaluate the diaphragmatic movement and postoperative analgesia following anterior glenoid, suprascapular, and interscalene nerve blocks in patients undergoing elective arthroscopic shoulder surgery.
- Conditions
- Interscalene Block, Suprascapular Nerve Block, Anterior Glenoid Nerve Block, Diaphragmatic Excursion
- Trial name
- NCT07090733
- Testing
- Interscalene brachial plexus block, Suprascapular nerve block, Anterior glenoid block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Pelvic Pain
Lidocaine Injection and Ischemic Compression on Chronic Pelvic Pain Treatment
Our hypothesis is that with comparison of effectiveness of two most common techniques of treatment for myofascial pain syndrome (injection of local anesthesia and ischemic compression) we could choice the most adequate to treat…
- Trial name
- NCT00628355
- Testing
- lidocaine, Ischemic compression
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Chronic Pain
Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance
Dual medication (guanfacine and morphine) as a standard treatment for chronic pain.
- Trial name
- NCT01681264
- Testing
- Morphine, Guanfacine 1mg, Guanfacine 2mg
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Massachusetts General Hospital
Sedation and Analgesia
Effect of Mild Sedation and Analgesia on Radial Artery Cannulation in Novice Residents
The aim of this study is to conduct a prospective, single-center randomized controlled study to investigate the effect of mild midazolam combined with sufentanil on radial artery cannulation in novice operators.
- Trial name
- NCT05863455
- Testing
- mild sedation and analgesia, control
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Affiliated Hospital of Jiaxing University
Hip Dysplasia
Can PLIA Reduce Early Post-operative Pain After PAO Surgery?
The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: 1.
- Trial name
- PILA PAO (NCT06519955)
- Testing
- Ropivacaine, Epinephrine, Ketorolac, NaCl (Saline)
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Michael C Willey
Nursing Caries, Pain, Postoperative
Effect of Foot Bath on Postoperative Sleep Quality and Pain
One of the most common problems in patients in the postoperative period is pain and the associated deterioration in sleep quality. Deterioration in sleep quality can cause pain to be perceived more severely.
- Conditions
- Nursing Caries, Pain, Postoperative, Sleep Deprivation
- Trial name
- NCT05705908
- Testing
- Hot Foot Bath 1, Hot Foot Bath 2
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Analgesia
Effect of Higher Volume and Lower Dose on Analgesic Quality During Labor Analgesia With Dural Puncture Epidural
It is aimed in this study to compare the effect of using local anaesthetics in a higher volume and lower dose on the total anesthetic consumption and quality of labor analgesia with dural puncture epidural technique.
- Trial name
- NCT06156709
- Testing
- Group I: Lower Volume with Higher Anaesthetic Concentration, Group II: Higher Volume with LowerAnaesthetic Concentration
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pain Management, Hemodialysis
Virtual Reality Distraction During Arteriovenous Fistula Puncture
The cannulation of arteriovenous fistula is a painful procedure in hemodialysis patients. Previous studies have shown the effectiveness of virtual reality in reducing pain during needle-related procedures
- Conditions
- Pain Management, Hemodialysis, Virtual Reality
- Trial name
- NCT05399199
- Testing
- virtual reality distraction
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University
Laparoscopic Colon Resection, Perioperative Analgesia
Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections
The aim of this study is to investigate the analgesic effects of intraperitoneal lignocaine (IPL) compared with intravenous lignocaine (IVL) after laparoscopic colon resections.
- Trial name
- NCT03105193
- Testing
- IV Saline bolus and infusion, IP Saline bolus and infusion, IV lignocaine bolus and infusion
- Where
- New Zealand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
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