Clinical trials: Analgesia, Postoperative
Surgery
The Study of Perioperative Intravenous Infusion of Lidocaine on Postoperative Analgesia in Patients Undergoing Single-port Thoracoscopic
The purpose of this study is to evaluate the effect of intravenous lidocaine infusion on pain and opioid dosage in patients undergoing single-port thoracoscopic surgery,and to evaluate the effects of perioperative catecholamine…
- Trial name
- NCT04043624
- Testing
- Lidocaine, Saline
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Surgery, Pain, Postoperative
2% Lidocaine Gel in Reducing Postoperative Pain Following Haemorrhoidectomy
The study is a randomized, double-blind, controlled trial evaluating the efficacy of 2% lidocaine gel in reducing postoperative pain and analgesic consumption after haemorrhoidectomy.
- Trial name
- NCT06420388
- Testing
- 2% Lidocaine Gel, Water-based Lubricant Gel (K-Y Gel), Standard Postoperative Analgesics
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- E-DA Hospital
Pain, Postoperative, Obesity
TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia
Cesarean deliveries are the most commonly performed surgery in the United States and account for 32.9% of all births.8,9 The ASA recommends the use of neuraxial opioids of post-cesarean analgesia partly because respiratory…
- Conditions
- Pain, Postoperative, Obesity, Respiratory Insufficiency
- Trial name
- NCT03282669
- Testing
- Intrathecal Morphine, Intravenous hydromorphone
- Sponsor
- Northwestern University
Pain
Pharmacokinetics, Safety, and Efficacy of SPRIX in 12 to 17 Year Old Patients vs. Adult Patients Undergoing Open Surgical Procedures
A SPRIX trial in pediatric subjects vs. adults undergoing open surgical procedures resulting in at least a moderate pain level. Subjects will receive SPRIX and blood samples will be collected for pharmacokinetic (PK) assessment.
- Trial name
- NCT01819610
- Testing
- SPRIX
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- American Regent, Inc.
Postoperative Pain, Nerve Block
Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy
This study aims to evaluate and compare the analgesic efficacy of two ultrasound-guided regional anesthesia techniques, the serratus anterior plane (SAP) block and the serratus posterior superior intercostal plane (SPSIP) block…
- Conditions
- Postoperative Pain, Nerve Block, Mastectomy, Patient Outcome Assessment
- Trial name
- NCT07510269
- Testing
- SAP Block, SPSIP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Uludag University
Hip Osteoarthritis
Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty
This clinical trial aims to assess the analgesic efficacy of ultrasound-guided FIB using different analgesic combinations administered into the iliac fascia compartment.
- Trial name
- FIB-PAIN (NCT06534697)
- Testing
- Naropin, 0.2% Injectable Solution in Sodium chloride, Naropin, 0.2% Injectable Solution in dextrose 5%, Dextrose 10 % in Water
- Volunteers
- 210 people
- Sponsor
- Foisor Orthopedics Clinical Hospital
Serratus Anterior Plane Block, Acute Pain
Combined SAPB in MICS
Minimally invasive cardiac surgery (MICS) has begun to be performed frequently in recent years. Compared to sternotomy, MISC reduces the risk of mediastinitis, leaves a more aesthetic scar, facilitates postoperative…
- Conditions
- Serratus Anterior Plane Block, Acute Pain, Postoperative Analgesia, Minimal Invasive Cardiac Surgery
- Trial name
- NCT06326320
- Testing
- Combined SAPB
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara City Hospital Bilkent
Butorphanol
Study on Gynecological Laparoscopy Under Total Intravenous Anesthesia
To investigate the effect of preemptive analgesia with tartaric acid butorphanol on postoperative pain in gynecological laparoscopy under total intravenous anesthesia with remifentanil.This randomised, double-blind…
- Trial name
- NCT06524596
- Testing
- tartaric acid butorphanol, normal saline, propofol and remifentanil
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Wuhan Children's Hospital
Pain After Photorefractive Keratectomy, VAS Will be Used to Assess Pain Postoperative
Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study
The current study aims at assessing the efficacy and safety of oral Gabapentin alone versus Diclofenac Potassium drugs for postoperative analgesia in patients undergoing surface ablation.
- Trial name
- NCT06752486
- Testing
- Giving post photorefractive keratectomy for pain relief
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Anesthesia, Analgesia
Genetic Variants and Perioperative Morbidity and Mortality
Prospective association study to analyse perioperative patients' outcome. Outcome comprises intraoperative and postoperative complications e.g.
- Conditions
- Anesthesia, Analgesia, Surgical Procedure, Operative
- Trial name
- NCT02124499
- Where
- Switzerland
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee
Clinical Application Observation on the Evaluation of Phantom Limb Pain With the Suralis System
This study tests whether a vibration-based feedback device (Suralis) can reduce phantom limb pain in people with lower-leg amputations over 3 weeks.
- Conditions
- Phantom Limb Pain After Amputation, Lower Limb Amputation Above Knee, Lower Limb Amputation Below Knee, Lower Limb Amputation Knee
- Trial name
- NCT07324109
- Testing
- Vibrotactile sensory feedback
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Median
Paraumbilical Hernia
Comparison of Extended Totally Extra-peritoneal Repair (ETEP) and Subcutaneous On-lay Endoscopic Approach (SCOLA) for Para-umbilical Hernia (PUH).
The goal of this clinical trial is to learn if one of two surgical techniques works better for treating paraumbilical hernias in adult men and women between 18 and 65 years old.
- Trial name
- NCT07434687
- Testing
- Extended Totally Extra Peritoneal Repair, Subcutaneous On-Lay Endoscopic Approach
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- King Edward Medical University
Post Operative Analgesia
Non-opioid Analgesic Combination With Morphine for Postoperative Analgesia.
The combination of different analgesic drugs and/or analgesia techniques is part of the standard management of postoperative analgesia.
- Trial name
- OCTOPUS (NCT01882530)
- Testing
- Paracetamol, Nefopam, Ketoprofen
- Where
- 19 sites in France
- Volunteers
- 223 people
- Sponsor
- Rennes University Hospital
Pain, Postoperative, Patient Comfort
Effect of Virtual Reality on Pain, Comfort and Satisfaction
The goal of this clinical trial is to examine the effect of virtual reality application on pain management, comfort, and care satisfaction in patients undergoing thyroidectomy-parathyroidectomy.
- Conditions
- Pain, Postoperative, Patient Comfort, Patient Satisfaction, Thyroidectomy
- Trial name
- NCT06199687
- Testing
- Use of Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Trakya University
Laparoscopic Abdominal Surgery
Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery
This clinical trial aims to investigate the impact of multimodal analgesia regimens on postoperative pain management and gastrointestinal function recovery following laparoscopic abdominal surgery.
- Trial name
- NCT06772545
- Testing
- Epidural Analgesia, Paravertebral Block, Transversus Abdominis Plane Block
- Volunteers
- 120 people
- Sponsor
- Xiaguang Duan
Nerve Block, Analgesia
ESPB vs TPVB for Postoperative Analgesia After the Nuss Procedure
This is a prospective randomized double-blind non-inferiority trial designed to test the hypothesis that erector spinae plane block (ESPB) is non-inferior to thoracic paravertebral block (TPVB) in postoperative pain control after…
- Conditions
- Nerve Block, Analgesia, Pectus Excavatum
- Trial name
- NCT05034601
- Testing
- ESPB group, TPVB group
- Where
- China
- Volunteers
- 68 people
- Sponsor
- West China Hospital
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Nausea, Vomiting
Effect of Dexamethasone Combined With Ondansetron on Postoperative Nausea and Vomiting in Patients With Patient-controlled Analgesia After Video-assisted Thoracoscopic Surgery
The purpose of this study is to study the effect of dexamethasone combined with ondansetron on postoperative nausea and vomiting in patients with patient-controlled analgesia after video-assisted thoracoscopic surgery.
- Trial name
- NCT01007500
- Testing
- Dexamethasone, Ondansetron
- Where
- South Korea
- Volunteers
- 123 people
- Sponsor
- Yonsei University
Analgesia
Efficacy and Safety of Erector Spinal Plane Block (ESPB) for Analgesia in Laparoscopic Cholecystectomy
Purpose: to evaluate the efficacy and safety of erector spinal block (ESB) for analgesia in laparoscopic cholecystectomy（LC）. Method: This study is a randomized, single-blind, controlled clinical trial.
- Trial name
- NCT04648345
- Testing
- Erector spinal plane block
- Volunteers
- 90 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Postoperative Pain
Peripheral Nerve Block Techniques During Cleft Palate
Regional blocks are commonly used in pediatric anesthesia to achieve adequate postoperative analgesia. Suprazygomatic Maxillary nerve block (SMN) and Greater Palatine nerve block (GPN) are regional blocks described for use during…
- Trial name
- NCT04467463
- Testing
- peripheral nerve block by 0.25% levobupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
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