Clinical trials: Analgesia, Postoperative
Surgery
Quadratus Lumborum Block for Analgesia Following Hip Arthroscopy
Evaluate difference in postoperative opiate consumption when patients do or do not receive a quadratus lumborum block preoperatively for hip arthroscopy.
- Trial name
- NCT03557125
- Testing
- QL Block, Saline Skin Wheel
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Postoperative Pain, Cesarean Delivery
Comparison of Intrathecal Bupivacaine With and Without Morphine for Post-operative Analgesia in Parturients Undergoing Elective Cesarean Section: A Randomized Controlled Trial
The goal of this clinical trial is to compare intrathecal bupivacaine with or without morphine for postoperative analgesia in patients undergoing elective cesarean section.
- Conditions
- Postoperative Pain, Cesarean Delivery, Analgesia, Obstetrical
- Trial name
- NCT07094802
- Testing
- Intrathecal morphine with bupivacaine, Hyperbaric Bupivicaine
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Pelvic Organ Prolapse (POP), Postoperative Pain
Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management
The goal of this clinical trial is to determine whether suzetrigine, when added to standardized multimodal postoperative analgesia improves pain control and reduces opioid consumption after apical suspension surgery for pelvic…
- Conditions
- Pelvic Organ Prolapse (POP), Postoperative Pain, Urogynecology
- Trial name
- SUSI (NCT07856654)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aditi Talkad
Current Smokers, Past Smokers
A Study on Analgesia and Related Outcomes for Patients With Tabacco Smoking
Numbers of postoperative PCA(Patient-Controlled Analgesia) related side effects among current, past and non smokers are determined by comparing and analyzing frequency distributions.
- Conditions
- Current Smokers, Past Smokers, Never Smokers
- Trial name
- NCT02266212
- Testing
- 5 ml arterial blood
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Neuropathic Pain, Chronic Pain
Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
- Conditions
- Neuropathic Pain, Chronic Pain, Thoracic Cancer
- Trial name
- NCT05909007
- Testing
- thoracic epidural insertion
- Where
- Greece
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Postoperative Pain, Nerve Block
Pain-relieving Methods After Laparoscopic Hemicolectomy
Effects of Transabdominal Plain Block and Quadratus Lumborum Block After Laparoscopic Hemicolectomy. The pain relief, bowel function and discharge.
- Trial name
- NCT05273281
- Testing
- Transabdominal plane block, Quadratus lumborum block
- Where
- Finland
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Third Molar Surgery, Post Operative Analgesia
'Propolis Versus Chlorhexidine Gluconate on Wound Healing After Third Molar Surgery: a Randomized Controlled Trial'
The goal of this study is to examine the effects of propolis gargle on wound healing following third molar surgery and to compare it with chlorhexidine gluconate.
- Trial name
- NCT07364253
- Testing
- Third molar Surgery with propolis gargle, Third molar surgery with chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Block
Retrolaminar Block Versus Tab Block in Abdomioasty
The aim of the study is to compare the analgesic efficacy of Us guided retrolaminar block versus transversus abdominis plane block in patient under going abdominal plastic surgery
- Trial name
- NCT06265402
- Testing
- Tab block versus retrolaminar block in abdominal plastic surgery
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tanta University
Postoperative Pain
TAP Block With Liposomal Bupivacaine Versus Pre-incisional Wound Infiltration With Bupivacaine for Postoperative Pain
In this randomized, controlled, double-blinded trial we plan to evaluate post-operative pain relief after laparoscopic-assisted Transversus Abdominis Plane (TAP) block using liposomal bupivacaine plus bupivacaine versus…
- Trial name
- LATAP (NCT02400645)
- Testing
- Pre-incisional wound infiltration, Laparoscope to place TAP block with liposomal bupivacaine, Liposomal bupivacaine
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Postoperative Pain
Caudal Block With Bupivacaine and Dexmedetomidine Versus TAP Block With Bupivacaine Alone for Postoperative Analgesia in Pediatric Undergoing Infraumbical Surgeries
Acute pain management for pediatric surgical patients intraoperatively and postoperatively is important for their comfort and psychological impact.
- Trial name
- NCT06183073
- Testing
- caudal block, Dexmedetomidine, TAP
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post-operative Pain Management
TAP Block , Intrathecal Morphine Or Their Combination For Post Operative Analgesia Following TAH
This randomized controlled clinical trial designed to evaluate the efficacy of transversus abdominis plane (TAP) block, intrathecal morphine, or their combination in postoperative pain relief, as assessed by time to first…
- Trial name
- NCT06882369
- Testing
- TAP Block, Intrathecal morphine injection, spinal anesthesia
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Minia University
Pain, Postoperative
Continuous Thoracic Epidural Versus Erector Spinae Plane Block for Postoperative Analgesia in Donar Hepatectomies.
Introduction Adult living related donor hepatectomy is associated with pain due to the sub-costal j-shaped incision, rib retraction using Thompson retractor, and diaphragm irritation1.
- Trial name
- NCT04151511
- Testing
- Continuous Erector Spinae Plane Block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa Clinical Research Center
Pain, Postoperative
Comaprison Between QLB and ESPB in Patients for PCNL Operation
comparing the subcostal oblique Quadratus Lumborum block and the Erector Spinae plane block in patients undergoing percutaneous nephrolithotomy operation to get the best and longest postoperative analgesic effect.
- Trial name
- NCT04277611
- Testing
- Subcostal Oblique Quadratus Lumborum Block and Erector Spinae Plain Block.
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Post Operative Pain
Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy
This study will help to answer the question, "Does injecting local anesthetic before laparoscopic instrument ports are placed decrease pain after surgery?" Patients participating will be randomly assigned to receive local…
- Trial name
- NCT01452633
- Testing
- 0.25% bupivicaine will be injected at the study port site prior to incision, Saline will be injected at the study port site prior to incision, Saline will be in injected into the port site prior to closure
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Postoperative Pain
Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia
The aim of this study is to compare the postoperative analgesic effect of intrathecal dexmedetomidine combined with bupivacaine and midazolam combined with bupivacaine in high tibial osteotomy.
- Trial name
- NCT06082232
- Testing
- Dexmedetomidine, Midazolam, Bupivacain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Old Age
Clinical Study of G Protein Biased Μ - Opioid Receptor Agonist Oliceridine for Optimizing Postoperative Analgesia Under General Anesthesia
Traditional opioid analgesia is a treatment method for moderate to severe pain. However, the use of opioid drugs is not without risks.
- Trial name
- NCT06668298
- Testing
- Oliceridine, Sulfentanil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Spinal Fusion, Adolescent Idiopathic Scoliosis
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients…
- Trial name
- NCT06067893
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nichole Doyle
Pain After Surgery
RISS Versus Lower Thoracic ESP Block for Analgesia After Laparoscopic Abdominal Surgery: A Randomized Trial
The goal of this clinical trial is to investigate the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block versus lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal…
- Trial name
- NCT07593300
- Testing
- Group A (n=35): Ultrasound-guided RISS block (RISS):, Group B (n=35): Ultrasound-guided lower thoracic ESP block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Nerve Block, Pain, Postoperative
Pudendal Nerve Block in Vaginal Surgery
The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared…
- Conditions
- Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse
- Trial name
- NCT04198714
- Testing
- Pudendal block
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center