Clinical trials: Analgesia, Patient-controlled
Pain
Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures
I. Background: Patients with multiple rib fractures are challenging from both pulmonary and analgesia perspectives. Adequate pain management is essential in prevention of complications secondary to decreased inspiratory volume.
- Trial name
- NCT04530149
- Testing
- Acetaminophen, Bupivacain, Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Antonios Likourezos
Urinary Catheterization As the Cause of Abnormal Reaction of Patient, or of Later Complication, Without Mention of Misadventure At Time of Procedure
Lidocaine Spray Use on Patients Comfort in Undergoing Bladder Catheterization
Bladder catheterization is a procedure frequently performed in emergency departments and may cause symptoms such as pain and discomfort in patients.
- Trial name
- NCT06585748
- Testing
- Lidocaine spray
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara City Hospital Bilkent
Acute Pain, Urinary Retention
Incidence of Urinary Retention in Patients Undergoing Unilateral Total Knee Arthroplasty- Comparison Between Continuous Epidural Analgesia and Single Shot Femoral Nerve Block- a Randomized Controlled Study (UriKANE)
This study aims to compare the incidence of urinary retention and requirement of bladder catheterization in patients undergoing total knee arthroplasty while receiving either continuous epidural analgesia or single shot femoral…
- Conditions
- Acute Pain, Urinary Retention, Post Operative Pain
- Trial name
- UriKANE (NCT02689011)
- Testing
- Femoral Nerve Block, Epidural
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Aga Khan University
Pain Management, Postoperative Pain
PCDD Generation 1 Oral Liquid Acetaminophen Delivery Evaluation
This prospective randomized pilot study evaluates the feasibility, acceptability, and preliminary efficacy of the Patient-Controlled Dispenser and Deactivator (PCDD) Generation 1 system for patient-controlled oral liquid…
- Trial name
- NCT07765238
- Testing
- PCDD Generation 1 system
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Postoperative Pain
Caudal Block v/s Local Wound Infiltration for Pain Control in Pediatric Patients After Operation for Inguinal Hernia
This randomized controlled trial aims to compare the analgesic efficacy of local wound infiltration with Ropivacaine versus Caudal Block with Ropivacaine in pediatric patients undergoing surgery for inguinal hernia
- Trial name
- NCT07747038
- Testing
- Caudal Block with Ropivacaine Intervention, Local Wound Infiltration with Ropivacaine Intervention, Intravenous Paracetamol Suspension Intervention
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Fatima Memorial Hospital
Plasma Cell Myeloma
Evaluating Effectiveness of Powered Drill Bone Marrow Biopsy
Since the introduction of the Jamshidi needle in 1971, new advances in bone marrow sampling have not been seen. In 2007, a new battery-powered bone marrow biopsy system was developed.
- Trial name
- NCT03078452
- Testing
- Power drill, Jamshidi needle
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Pain, Postoperative; Anesthesia, Regional
Analgesic Efficacy of Ultrasound Guided Paravertebral Block in Percutaneous Nephrolithotomy Patients
The aim of this study is to investigate the analgesic effects of thoracal paravertebral block in the patients undergoing percutaneous nephrolitotomy. Paravertebral block was applied to the study group.
- Trial name
- NCT04406012
- Testing
- paravertebral block
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Postoperative Analgesia, Hand Strength
Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia
In the study that was conducted from 05.01.2009 - 31.12.2012. 120 patients were examined. By drawing random numbers, the patients were randomized into 3 groups for postoperative analgesia: 1. Diclofenac 2 mg/kg/day - control, 2.
- Conditions
- Postoperative Analgesia, Hand Strength, Health Related Quality of Life, Chronic Shoulder Pain
- Trial name
- NCT05829707
- Testing
- Diclofenac Sodium, Levobupivacaine bolus analgesia, Levobupivacaine PCA group
- Volunteers
- 120 people
- Sponsor
- Osijek University Hospital
Postoperative Pain
A Multicenter Study: Dexmedetomidine Combined With Sufentanil for Patient Controlled Intravenous Analgesia After Caesarean Section
The purpose of this multicenter study is to evaluate the effectiveness and safety of dexmedetomidine combined with sufentanil for patient-controlled analgesia after caesarean section
- Trial name
- NCT02741219
- Testing
- Normal saline, Dexmedetomidine, Sufentanil
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Obstetrics & Gynecology Hospital of Fudan University
Pain, Advanced Cancer
Sativex® for Relieving Persistent Pain in Participants With Advanced Cancer
This 9-week study aimed to determine the efficacy, safety and tolerability of nabiximols (Sativex®) as an adjunctive treatment, compared with placebo in relieving uncontrolled persistent chronic pain in participants with advanced…
- Trial name
- NCT01262651
- Testing
- Nabiximols
- Where
- 72 sites in United States, Belgium and 10 more
- Volunteers
- 397 people
- Sponsor
- GW Pharmaceuticals Ltd
Pain
Patient Controlled Epidural Analgesia Versus Continuous Epidural Infusion: Obstetrical and Neonatal Outcomes
The investigators intend to perform a large randomized trial using standardized obstetrical and anesthetic practice at a single institution to determine the effects of patient controlled epidural analgesia on obstetrical and…
- Trial name
- Epidural (NCT00810914)
- Testing
- bupivicaine epidural, bupivicaine epidural infusion patient epidural, bupivicaine
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Post Operative Pain, Hyperalgesia
Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone
Background: In perioperative period inhibition of N-Methyl-D-Aspartate receptor prevents opioid-induced hyperalgesia and reduce postoperative opioid requirement after abdominal surgery.
- Trial name
- NCT01594047
- Testing
- ketamine infusion, Methadone PCA
- Where
- Italy
- Volunteers
- 113 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Post Operative Analgesia
Interest of Continuous Ropivacaine Administration Through an Elastomeric Pump (Pain Buster) for the Surgery of Latissimus Dorsi and Serratus Micro Anastomotic Flaps
Continuous bupivacaine administration through an elastomeric pump (Pain Buster) has been found effective for post operative analgesia in a large range of surgery.
- Trial name
- NCT00724685
- Testing
- Naropeine (Ropivacaine)
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Nantes University Hospital
Hemorrhoid Pain
Post Hemorrhoidectomy Anorectal Pain
This is a quality assurance trial to evaluate the effectiveness of guided breathing exercises on reducing the symptoms of hemorrhoidal disease in colorectal surgery patients.
- Trial name
- NCT03240185
- Testing
- deep breathing exercises
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Hip Arthropathy
ESP Block vs FIB in Patients Undergoing Hip Arthroplasty
The aim of this study is to compare between the analgesic efficacy of ESP block and FIB in patients undergoing hip arthroplasty.
- Trial name
- NCT05015517
- Testing
- Erector spinae plain block, Fascia Iliaca block
- Volunteers
- 54 people
- Sponsor
- Cairo University
Pain Management
Analgesic Efficacy of Ultrasound-Guided Deep Iliacus Plane Block in Patients Undergoing Hip Fracture Surgery
Hip fracture surgery is commonly associated with moderate to severe postoperative pain, which may delay mobilization and increase the need for opioid analgesics.
- Trial name
- NCT07716540
- Testing
- Ultrasound-Guided Deep Iliacus Plane Block With Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Labor Pain
A Comparison Study of Patient Controlled Epidural Analgesia (PCEA) With and Without Basal Infusion Using Ropivacaine 0,15% and Fentanyl μg/ml for Pain Relief in Labor, Assessment of Efficacy and Maternal Satisfaction.
This is a prospective, randomized, double blind study, in which a comparison of patient controlled epidural analgesia (PCEA) of continuous background infusion with demand dose and demand only, using ropivacaine 0,15% and fentanyl…
- Trial name
- NCT02084589
- Testing
- PCEA with basal infusion and demand dose using ropivacaine 0,15% and fentanyl 2μg/ml for pain relief in labor, PCEA without basal infusion (demand only) using ropivacaine 0,15% and fentanyl 2μg/ml for pain relief in labor
- Where
- Greece
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Total Knee Arthroplasty
Treatment of Postoperative Pain After Total Knee Arthroplasy Using Intravenous Lidocaine Infusion
Total knee replacement is often associated with severe postoperative pain, especially in the first 24 hours. Patient controlled analgesia (PCA) and continuous femoral block with PCA are commonly used to treat postoperative pain…
- Trial name
- NCT00616850
- Testing
- Continuous femoral catheter block, Lidocaine, Preservative free normal saline
- Where
- United States
- Sponsor
- Loma Linda University
Pain, Burning
Ketamine Continuous Infusion on Opioid Consumption and Pain Management in Severe Burned Patients
The purpose of this study is to evaluate the efficacy of ketamine in continuous infusion in the control of pain intensity, the impact on the consumption of opioids and observe the side effect profile in patients suffering from…
- Trial name
- ccimb (NCT02860117)
- Testing
- Ketamine continuous infusion
- Where
- Brazil
- Sponsor
- University of Sao Paulo General Hospital
Morphine Consumption, Postoperative Pain
Ultrasound-Guided Pericapsular Nerve Group Block for Pain Control After Hip Surgery
This study evaluated whether an ultrasound-guided pericapsular nerve group (PENG) block could reduce pain and morphine use during the first 24 hours after hip surgery.
- Trial name
- NCT07906613
- Testing
- Ultrasound-Guided Pericapsular Nerve Group Block with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
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