Clinical trials: Anal Incontinence
Urinary Incontinence, Fecal Incontinence
Pilot: Mind Over Matter: Healthy Bowels, Healthy Bladder
The study is to pilot-test an innovative, combined urinary/bowel continence workshop in two Wisconsin communities. Between 8-15 women with incontinence will be enrolled in each of the two pilot communities and will complete three…
- Conditions
- Urinary Incontinence, Fecal Incontinence, Accidental Bowel Leakage
- Trial name
- NCT02671747
- Testing
- Mind Over Matter; Healthy Bowels, Healthy Bladder
- Volunteers
- 56 people
- Sponsor
- University of Wisconsin, Madison
Fecal Incontinence
Percutaneous Tibial Nerve Stimulation for Patients With Fecal Incontinence
Percutaneous tibial nerve stimulation is introduced as regular treatment option for fecal urge continence at the Cantonal Hospital St. Gallen.
- Trial name
- NCT01162525
- Testing
- Percutaneous tibial nerve stimulation (pTNS)
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- Cantonal Hospital of St. Gallen
Incontinence-associated Dermatitis, Nursing Care
Developing Of A New Incontinence Care Product
The aim of this randomized controlled clinical trial, prospective study is to developing a new incontinece care product for containing the fecal incontinence and to examine the effect of this new product on prevention of perineal…
- Trial name
- NCT02991833
- Testing
- A New Incontinence Care Product, Diaper
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Ege University
Fecal Incontinence
Efficacy, Safety, and Performance Study of a Novel Device Designed to Manage Fecal Incontinence in Hospitalized Bedridden Patients With Liquid to Semi-formed Stool.
The purpose of this study is to evaluate the safety, efficacy, and functionality of the Consure 120 Stool Management System in hospitalized bedridden patients suffering from fecal incontinence.
- Trial name
- NCT02208258
- Testing
- Consure 120 Stool Management System
- Where
- United States
- Sponsor
- Consure Medical Pvt. Ltd.
Faecal Incontinence With Faecal Urgency, Rectal Cancer
Efficacy of a Novel High Intensive Percutaneous Tibial Nerve Stimulation on Faecal Incontinence in Patients With Low Anterior Resection Cancer Syndrome After Rectal Cancer Surgery
This study aims to assess and evaluate the clinical efficacy of an intensified form of Percutaneous tibial nerve stimulation (PTNS) compared to standard conservative treatment for low anterior resection syndrome (LARS).
- Conditions
- Faecal Incontinence With Faecal Urgency, Rectal Cancer, Radiotherapy Side Effects, Low Anterior Resection Syndrome (LARS>20)
- Trial name
- HiPLARS (NCT07862673)
- Testing
- Percutaneous Tibial Nerve Stimulation
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Fecal Incontinence
Autologous Myoblast Intrasphincteric Injection for Fecal Incontinence
This project aims to offer autologous muscle-derived progenitor cell injection as an efficient mini-invasive surgical therapy that would be simple for the patient and could be used in a majority of cases, including in young women…
- Trial name
- MIAS (NCT01523522)
- Testing
- Myoblast injection, saline solution injection
- Where
- 2 sites in France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Rouen
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)
UCon is a medical device for treatment of the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Fecal Incontinence, Fecal Incontinence With Fecal Urgency
- Trial name
- NCT06091566
- Testing
- UCon-Bar
- Where
- 3 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- InnoCon Medical
Fecal Incontinence
Sacral Neuromodulation as Treatment for Fecal Incontinence
The objective of this study is to investigate if low level laser therapy will do more good than harm for patients with severe refractory fecal incontinence. It is a proof of concept study without a placebo arm.
- Trial name
- LLLT-FI (NCT03825575)
- Testing
- Low level laser therapy (LLLT)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Multiple Sclerosis, Constipation
Symptoms and Treatment Assessment of Ano-Rectal Disorders in Multiple Sclerosis Patients : STAR-Q
Multiple sclerosis (MS) is known to cause urinary disorders, sexual and bowel dysfunction. Urinary symptoms due to MS are well known and profit of multiple questionnaire or tool developed in MS patients.
- Conditions
- Multiple Sclerosis, Constipation, Fecal Incontinence
- Trial name
- STAR-Q (NCT04996186)
- Testing
- Clinical interviews
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Pierre and Marie Curie University
Fecal Incontinence
Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence
The purpose of this study is to evaluate and compare treatment with fiber and loperamide for fecal incontinence.
- Trial name
- FIRM (NCT00727649)
- Testing
- Psyllium powder, Loperamide
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- US Department of Veterans Affairs
Rectal Prolapse, Fecal Incontinence
Clinical Outcomes of Rectopexy for Rectal Prolapse
This study evaluates the clinical outcomes of patients who underwent rectopexy for rectal prolapse, ODS or FI. Rectopexy is a surgical procedure used to restore and fix the rectum in its normal position.
- Conditions
- Rectal Prolapse, Fecal Incontinence, Rectopexy, Obstructive Defecation Syndrome
- Trial name
- NCT07848308
- Testing
- anterior mesh rectopexy
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- Lukas Marti
Fecal Incontinence
A Feasibility Study of a Fecal Incontinence Management System for Medical Use
The purpose of this feasibility study is to evaluate the performance and skin-friendliness of the barrier of the Fecal Incontinence Management System.
- Trial name
- NCT00556972
- Testing
- Fecal Incontinence Management System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Coloplast A/S
Anus Cancer, Fecal Incontinence
Function Following Laser for Anal Intraepithelial Neoplasia (FLAN)
High-grade squamous intraepithelial lesions (HSIL) and anal cancer are rising in incidence and at highest risk are HIV positive men who have sex with men (MSM).
- Conditions
- Anus Cancer, Fecal Incontinence, Anal Intraepithelial Neoplasia, Post Operative Pain
- Trial name
- FLAN (NCT04109573)
- Testing
- high resolution anal manometry
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Homerton University Hospital NHS Foundation Trust
Fecal Incontinence, Irritable Bowel Syndrome With Diarrhea
The Role of Fiber in the Prevention and Treatment of Fecal Incontinence
The purpose of this study is to determine the effect of fiber supplementation on the fecal metagenome and metabolome in relation to symptoms and anorectal physiology in post-menopausal women with irritable bowel syndrome with…
- Trial name
- NCT04806386
- Testing
- Psyllium
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Massachusetts General Hospital
Fecal Incontinence
Clinical Study to Investigate the Effectiveness of the TOPAS System to Treat Fecal Incontinence
The purpose of this study is to demonstrate that the TOPAS System effectively treats fecal incontinence in women as measured by a 50% reduction in the number of FI episodes in a 14 day bowel diary at 12 months.
- Trial name
- TRANSFORM (NCT01090739)
- Testing
- TOPAS Treatment for Fecal Incontinence
- Where
- 14 sites in United States
- Volunteers
- 207 people
- Sponsor
- ASTORA Women's Health
Low Anterior Resection Syndrome, Malignant Anal Neoplasm
Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study
This phase II trial studies how well sacral nerve stimulation works in treating low anterior resection syndrome or fecal incontinence (the body's passage of stool without control) in patients with rectal cancer that has spread to…
- Conditions
- Low Anterior Resection Syndrome, Malignant Anal Neoplasm, Malignant Bladder Neoplasm, Malignant Cervical Neoplasm
- Trial name
- NCT04066894
- Testing
- Explantation, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Perianal Fistula, Fistula-in-Ano
Open Fistulectomy vs. Laser Closure for Low Perianal Fistula
Perianal fistula is an abnormal tunnel connecting the anal canal to the perianal skin, frequently causing chronic pain, discharge, and impaired quality of life.
- Conditions
- Perianal Fistula, Fistula-in-Ano, Low Perianal Fistula
- Trial name
- NCT07797842
- Testing
- Fistula-tract Laser Closure (FiLaC), Open Fistulectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Urinary Incontinence, Anal Incontinence
Tridimensional Pelvic Floor Ultrasound and Quality of Life Scores Questionnaires in Nulliparous or Parous Women
Evaluation of the impact of the delivery in the system of suspension and sustentation of pelvic floor, by 3D ultrasound and quality of life questionnaires.nt
- Conditions
- Urinary Incontinence, Anal Incontinence, Sexual Dysfunction, Self Esteem
- Trial name
- NCT03656601
- Testing
- 3D pelvic ultrasound
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colonic Neoplasms, Rectal Neoplasms
Endoscopically Assisted Colostomy With Colopexy for Critically Ill Patients Without General Anesthesia or Laparotomy
Indications for colostomy are rectal or anal cancer, diverticular disease, radiation enteritis, complex perirectal fistulas, anorectal trauma, severe incontinence, motility and functional disorders.
- Conditions
- Colonic Neoplasms, Rectal Neoplasms, Fecal Incontinence
- Trial name
- EACC (NCT02308631)
- Testing
- ENDOSCOPICALLY ASSISTED COLOSTOMY WITH COLOPEXY
- Where
- Brazil
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo