Clinical trials: Anal Fistula
Anal Fistula
"Feasibility and Safety of the Calcium Alginate Hydrogel Sealant for the Treatment of Cryptoglandular Fistula-in-ano: Phase I/IIa Clinical Trial"
Background: Complex perianal fistulas pose a challenge to surgeons since the fistulous tract must be eliminated without impairing continence.
- Trial name
- NCT04740086
- Testing
- Calcium alginate hydrogel
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Anal Fistula
Endoscopic Treatment of Complex Anal Fistulas
This is a randomised controlled trial to evaluate the outcome of treatment of complex perianal fistula by Video-assisted anal fistula treatment (VAAFT) compared to fistulectomy and sphincter reconstruction as standard surgical…
- Trial name
- VAAFT (NCT02585167)
- Testing
- operation, VAAFT
- Where
- Denmark
- Volunteers
- 47 people
- Sponsor
- University of Southern Denmark
Anal Fistula, Perianal Fistula
Comparison Of Surgical Outcomes Between Ligation Of Intersphincteric Fistula Tract And Fistulotomy With Seton In Perianal Fistula
This study aims to compare two commonly used surgical techniques for the treatment of perianal fistula: Ligation of the Intersphincteric Fistula Tract (LIFT) and fistulotomy with seton.
- Conditions
- Anal Fistula, Perianal Fistula, Fistula-in-ano
- Trial name
- LIFT-SETON (NCT07579715)
- Testing
- Ligation of Intersphincteric Fistula Tract (LIFT), Fistulotomy with Seton Placement
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Islamabad Medical and Dental College
Anal Fistula
Treatment of Complex Anal Fistulas Using Centrifuged Adipose Tissue Containing Progenitor Cells
In the treatment of complex anal fistulas transplant of freshly collected autologous adipose tissue mechanically fragmented or centrifuged adipose tissue (CAT) might be an alternative to in vitro expanded autologous or allogeneic…
- Trial name
- CAT (NCT04326907)
- Testing
- Autologous centrifuged adipose tissue (CAT) injection after anal fistulectomy
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Anal Cancer
Drainage Seton With Flap Versus EAS Preserving Seton in Treatment of Transsphincteric Anal Fistula
Patients with high trans-sphincteric anal fistula will be randomized to one of two equal group: group 1 will have drainage seton with mucosal advancement flap and group 2 will undergo external anal sphincter sparing seton
- Trial name
- NCT03983174
- Testing
- Drainage seton with flap, EAS sparing seton
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Hemorrhoids, Fissure in Ano
Multi-Drug Analgesia vs. Standard Solution for Anal Surgery
The primary aim is to test the magnitude and duration of analgesia provided by single dose multi-drug analgesia administered for perianal block, and compare with standard solution (Marcaine \& Lidocaine in 1:1 mixture - Total 60…
- Conditions
- Hemorrhoids, Fissure in Ano, Fistula;Rectal
- Trial name
- NCT03105674
- Testing
- Multi-drug local anesthetics (Combination), Standard local anesthetics (Combination)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Anal Fistula
Do Antibiotics Prevent Anal Fistulae Formation?
Purpose: This randomized study assesses the effects of antibiotics on the formation of fistulae after drainage of anorectal abscesses.
- Trial name
- NCT01012843
- Testing
- Amoxicillin-Clavulanate
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Ankara University